The Move to Biologics Bioanalysis is Easier Than You Think
The move to large molecules in Pharma is accelerating, but for those with extensive experience with small molecule bioanalysis, the shift to biologics can be challenging.
The BioBA Solution enables you go from samples to data with confidence. Everything you need in one place: from packaged sample prep kits linked with lab automation to advanced LC-MS/MS systems and software, plus ready-to-use methods and consulting from application experts in biologics bioanalysis. Explore below to learn more about how the BioBA Solution can accelerate your move into large molecule quantitation.
From small peptides to large proteins, biologics requires complex sample preparation techniques that leave little room for error. The BioBA Sample Preparation Kit simplifies your workflow by providing ready-to-use reagents and consumables for every step of the sample prep process with virtually everything you need for your biologics bioanalysis work. Learn more in the video below how the high-capacity sample enrichment beads, digestion enzymes, buffers, and the protocols can get you started right away in large molecule quantitation.
Why Climb when you can Fly - Biologics Bioanalysis Solution (3:39 min)
The BioBA Solution not only provides packaged kits and protocols, it offers automated sample preparation with the Beckman Coulter Biomek Laboratory Automation Workstation. The result: greater productivity with more consistent, dependable results.
The Biomek workstation addresses each aspect of liquid handling – pipetting, dilution, dispending, and integration – into a single automated system that is as powerful as it is flexible. With this solution, you don’t need to be an automation expert. The Biomek Method Launcher software gives operators increased confidence when running the automated BioBA workflow by guiding you through the set-up, and providing progress milestone updates as well as the ability to monitor status remotely.
Together with BioBA lab-tested iMethod™ Applications, the Biomek Workstation makes sample prep easy and efficient.
Automation for Large Molecule Bioanalysis Sample Prep (3:16 min)
The newest addition to our LC family, the SCIEX ExionLC™ System offers exceptional baseline stability, ultra-low carryover performance, and excellent sample injection reproducibility. For high sensitivity with limited sample sizes, the SCIEX M3 MicroLC ensures accurate and reproducible results for peptide quantitation.
With multiple approaches to selectivity improvements, the QTRAP 6500+ System with SelexION+ Technology offers the flexibility to achieve the performance to handle any biologics quantitation challenge.
When you have limited sample volume available and need high-throughput processing, the M3 MicroLC System offers unparalleled sensitivity for biotherapeutic development.
Software That Drives Productivity
DiscoveryQuant™ Software reduces tedious LC-MS method development time with a fast, robust and reliable process that optimizes methods for hundreds of small or large molecules. It expedites the method development process using existing database information, automates on-column optimization, and can easily analyze and process multiple samples simultaneously.
MultiQuant™ Software offers an intuitive user interface and the ability to handle large data sets to effectively address bioanalytical reporting for all molecule types. MultiQuant Software features a robust Watson LIMS link and enhanced compliance features that enable you to ensure data quality, security and compliance.
Ready-to-use, lab-proven iMethod™ Applications can help you get your large molecule studies running. You can select from pre-built methods that map to your compounds of interest, saving significant method development time. Plus, our tested methods ensure consistent results and portability across your labs for maximum productivity. SCIEX offers a full range of verified iMethod Applications for your immediate use:
Download application notes for these iMethod Applications by filling the form to the right.
BioBA Certification Program
We have designed a certification program especially for bioanalytical experts who would like to transition to peptide and protein quantitation. The combination of lecture and hands-on experience will leave you confident in your ability to face the challenges of large molecule bioanalysis.
The training includes three components:
Introductory eLearning module on basics of peptide and protein bioanalysis
A three-day on-site hands-on sample preparation training which includes immunocapture, digestion and signature peptide quantification using SCIEX TripleQuad™ or QTRAP® LC-MS/MS systems.
Follow up remote support and unlimited access to instructional videos at the SCIEXNow website.
Contact our training department for additional information including a detailed course agenda: training.sciex.com