Electroosmotic Flow (EOF) describes the movement of ions through a solute under the control of an applied potential. In CE, the capillary columns consist of silica with silanol groups exposed on the inner surface. The exposed silanol groups are ionized above pH 3, therefore creating a negatively charged inner capillary surface. Cations present in ionic solutions will migrate toward the negatively charged wall forming an electric double layer. Generation of an electrical potential across the column now causes cations to migrate towards the cathode. Electroosmotic flow results as the solvated cations clustered at the capillary walls drag the bulk solution in tow towards the cathode.