The United States Environmental Protection Agency (EPA), requires a list of no more than 30 unregulated contaminants to be monitored in public drinking water systems under the 1996 Safe Drinking Water Act (SDWA). Known as the Unregulated Contaminant Monitoring Rule (UCMR), a new list is published every five years. The last rule, UCMR3, was published May 2, 2012, and it is the focus of the following application note, Analysis of perfluoroalkyl acids specified under the UCMR3 using the QTRAP® 6500 LC-MS/MS System, “which can be found in the Environmental Compendium Volume 2.
Using the guidelines laid out by EPA Method 537, “A Determination of Selected Perfluoroalkyl Acids in Drinking Water by Solid Phase Extraction and Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS),” this application note describes the performance of the QTRAP 6500 System to analyze perfluorinated alkyl (or “perfluoroalkyl”) acids, known as PFAAs, in drinking water. Within the scope of EPA Method 537, there are 14 PFAAs, and 6 of these are included in the UCMR3 monitoring list.
For the analysis described in the application note, sample preparation and data processing were carried out according to EPA Method 537 without deviation unless specifically noted. The analysis was performed using the QTRAP 6500 System coupled with the Agilent 1260 HPLC system with an Eksigent® ULC 100 HTC-xt autosampler. Quantification was performed using MultiQuant™ 3.0 Software.
Related to RUO-MKT-03-5359-A
About the author
Philip Taylor has more than 10 years of experience in mass spectrometry. He is currently a Senior Global Marketing Manager at SCIEX and focuses on strategic marketing initiatives to drive applied markets, including food, environmental and forensic LC-MS/MS solutions.