https://sciex.com/content/SCIEX/na/us/en


LC-MS/MS Analysis of Emerging Food Contaminants

Dec 16, 2016 | Blogs, Food / Beverage | 0 comments

Ever wish you had access to the most up to date application methods but don’t know where to find them? The Food and Beverage Compendium is your one-stop resource for research notes ranging from pesticides, allergens, and antibiotics to mycotoxins, vitamins, and packaging. An example of what you can find inside includes the detection of pesticide 1080 (sodium fluoroacetate), as a food contaminant in milk and infant formula, which New Zealand is heavily dependent upon to control its rodent population.

The reason for this research concerns a 2014 threat, in which letters containing milk powder were sent to the New Zealand farming and dairy industry leaders containing a concentrated version of 1080 used for pest control. Accordingly, only cyanide is more powerful when it comes to killing pests, but is also dangerous to humans. Pesticide 1080 is reportedly biodegradable and does not remain in soil or waterways. An alternative to 1080 application is trapping, which is labor intensive and supply driven.

Therefore, to offer labs a viable way to test for the presence of 180, a liquid chromatography method coupled with tandem mass spectrometry (LC-MS/MS) was used as an analytical technique to detect polar analytes in complex food samples. You can find out more about the process in which the-the SCIEX QTRAP® 4500 System with Turbo V™ source was operated using an ESI probe in negative polarity by downloading the entire compendium. It is just one of 16 research notes dedicated to pesticides.Download The Food Compendium >

Supporting new CRISPR gene editing systems

Prime editing (PE) is a next-generation gene editing technology that utilizes a Cas9 protein fused to a prime editing guide ribonucleic acid (pegRNA) to achieve high CRISPR/Cas9 editing efficiency and precision. However, the length requirement of pegRNAs at 120–250 nucleotides (nt) and their high level of secondary structure formation present analytical challenges for the purity analysis of chemically synthesized pegRNAs during development and quality control (QC).

A new approach for comprehensive AAV evaluation including full and empty analysis

Certain next-gen vaccines and gene therapy applications rely on the usage of adeno-associated viruses (AAV) as a delivery vehicle. To ensure the safety and efficacy of viral vector drugs, multiple critical quality attributes (CQAs) need to be well characterized.

The rising tide of food allergies: Common questions and crucial insights

Allergy policies for nut-free commercial flights and nut-free childcare settings are not a rare occurrence nowadays—the reason is a rise in food allergies. Nuts are the most potent allergenic foods in terms of the amount that is required to elicit an allergic reaction and the severity of those reactions.

Posted by

0 Comments

Submit a Comment

Wordpress Social Share Plugin powered by Ultimatelysocial