by Roxana McCloskey | Mar 28, 2024 | Biopharma, Blogs, Intabio ZT system, ZenoTOF 7600 system
Read time: 5 minutes Monitoring product quality attributes (PQAs) throughout monoclonal antibody (mAb) development is vital to ensuring drug safety and efficacy. By adopting orthogonal analytical techniques and integrating new technologies that have the potential to...
by Kerstin Pohl | Mar 14, 2024 | Biopharma, BioPhase 8800 system, Blogs, ZenoTOF 7600 system
Read Time: 7 minutes Interviewee: Jane Luo (PhD), Senior Scientist, SCIEX Lipid nanoparticles (LNPs) are widely used vehicles for mRNA-based therapeutics and vaccines. However, ionizable lipids used in LNPs can be susceptible to N-oxide impurities that can cause...
by Pierre Negri | Mar 11, 2024 | Blogs, Forensic, SCIEX OS software, Toxicology, ZenoTOF 7600 system
Read time: 4 minutes LC-MS/MS is a powerful analytical tool in forensic toxicology testing that can support a variety of testing regimes such as screening, confirmation and quantitative workflows. More specifically, analysis of NPS using LC-MS/MS provides many...
by Pierre Negri | Mar 11, 2024 | Blogs, Clinical, Forensic, QTRAP / Triple Quad, Toxicology
The development of analytical methods for the detection and quantitation of drugs and metabolites in a range of biological matrices is a challenging process. Forensic toxicology labs need a reproducible and reliable methodology to ensure the robustness of the data and...
by Garrett Deletti | Mar 7, 2024 | Other, QTRAP / Triple Quad, Questions, SCIEX OS software
When using SciexOS software analytics application: If a filename was accidentally repeated for multiple sample analyses (i.e. copy and paste line items in the batch builder, then forgot to change filename for individual instances), is it possible to change the...
by Rahima Danishmand | Mar 7, 2024 | CE, QA/QC, Questions, SCIEX OS software
How do I set up my processing method to calculate the RRT of the main peak to 10kD in karat 32 software?
by Arielle Cocozza | Mar 7, 2024 | LC, Other, Questions, SCIEX OS software
I have a Exion LC AD fitted with the Exion LC AC PFAS kit – I’m looking into running another application on the instrument alongside PFAS analyses that uses 0.2% Formic Acid in H2O as one of the mobile phases. I can’t find any literature on whether...
by Henriette Krenkel | Mar 7, 2024 | Other, QTRAP / Triple Quad, Questions, SCIEX OS software
Hi, When creating a .csv report in Sciex OS, the file automatically opens up in Excel. Is there a way to change this behaviour, so that reports are just saved without being opened? Kind regards, Henriette
by Henriette Krenkel | Mar 7, 2024 | Other, QTRAP / Triple Quad, Questions
Hi, After updating Analyst to version 1.7.3 we tried to implement the injection counter according to https://sciex.com/kr/support/knowledge-base-articles/how-to-initiate-injection-counter-in-analyst-software-version-1-7-3_en_us. We use a column switching valve...
by WuXi AppTec | Mar 7, 2024 | LC, Other, Questions
When saving data or result table to a network share sometime we get an error 1- no desk space available, “we have 75 GB desk space available” or 2- another error “you don’t have permission”, use have read and wright permission to the...