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Knowledge Base is your tool to finding answers about common questions. Browse all Knowledge Base articles below.
Migrating an Analyst® Software Compound Library to Sciex OS Software To migrate compounds in an Analyst® software library to Sciex OS software, navigate to the Library module in Sciex OS software, and select Analyst Compound Library in the import options. The imported library must be named. Instructions for naming the library are included here.
10/03/2019
SCIEX OS
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Analyst Software
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LibraryView Software
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When setting up MPX 2.0 software's carryover detection feature in the Define limit values screen (step 3), the low limit for each component must be defined using the lower limit of quantitation (LLOQ) or from the cut-off limit determined from the standard curve.
09/29/2019
MPX Software
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Mass tolerance and threshold values for reporting iTRAQ ratios can be tuned by editing a configuration file.
10/07/2016
Academia Omics
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iTRAQ Reagent
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Protocol for Downgrading SCIEX OS 1.4 to 1.3 If downgrading from SCIEX OS 1.4 to 1.3 is required, follow the instructions below.
07/02/2018
SCIEX OS
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What Are the Standard Addition Columns in a SCIEX OS Software Results Table? Sciex OS software allows users to process standard addition results by selecting the Standard Addition option in the Components tab of the processing method in the Analytics mode. What do the new standard addition column headers mean?
11/04/2021
SCIEX OS
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Locating the Most Recent Quantitation Method Used in MultiQuant™ Software To locate the most recently used quantitation methods used in MultiQuant™ software, select the File menu and then select the Recent Quantitation Methods option. This menu option allows for the most recently accessed methods to be viewed.
05/14/2020
MultiQuant Software
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Choosing the Peak Selection Criteria when Using SCIEX OS AutoPeak Integration Algorithm This articles explains what type of peak selection criteria can be used with the SCIEX OS AutoPeak integration algorithm.
02/15/2019
SCIEX OS
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Applying the Saturation Correction when Working with SCIEX OS AutoPeak Integration Algorithm Saturation correction can correct for detector saturation effects. To make these changes in SCIEX OS software when working with the autopeak integration algorithm, select the saturation correction button in the method and specify the threshold value.
02/15/2019
SCIEX OS
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Why Does My Area Ratio Show as N/A in MultiQuant™ Software? Area ratios that give a value of N/A in MultiQuant™ software are likely due to an internal standard not being integrated or only being designated, but not assigned, to an analyte.
05/16/2017
MultiQuant Software
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Analyst® Software Sub-projects Cannot Be Used with Custom Quant Table Settings To create and apply custom results table settings in Analyst® software, sub-projects cannot be in use.
12/27/2018
Analyst Software
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Installing ProteinPilot™ 4.5 and 5.0.x Software on the Same PC For software users who need to view the older group files, maintaining a separate computer with ProteinPilot™ software 4.0 installed is the recommended best approach. Alternatively, both versions, 5.0.x and an older version, can be installed on the same computer, but this is an unsupported configuration.
05/13/2020
ProteinPilot Software
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Unable to Import Batch Files in XLSX Format in the Batch Editor in Analyst® 1.7 Software Importing an XLSX batch file into Analyst® 1.7 software may cause an error, and the batch file import will not be successful. The XLSX format is only available if the version of Microsoft Office that is installed is a 32-bit application. Users with a 64-bit version of Office will see these batch import errors, and must install additional software components to support XLSX type spreadsheets with Analyst software.
03/20/2020
Analyst Software
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How to delete Results Table Settings in Analyst Quantitation Mode Where to find the 'remove' button for the results table settings
10/23/2017
Analyst Software
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On Windows 7 I have the Manually Integrate script installed but when running the script an error message appears saying that the script is not installed.
07/08/2016
Analyst Software
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What File Format Can Report Templates Be Created In? Report templates—used to create reports from results tables generated in Sciex OS, MultiQuant™ and Analyst® software—must always be in the format of a Word document with a file extension .docx. However, the output report itself can be created in several formats including Word, HTML, PDF, and CSV.
10/16/2019
SCIEX OS
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Analyst Software
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MultiQuant Software
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After upgrading Analyst® TF software 1.8 to version 1.8.1, the Eksigent control software no longer displayed the option to chose the ekspert™ nanoLC 400 autosampler. To resolve this issue, in the Eksigent control software, the autosampler driver for the nanoLC 400 must be unregistered and then re-registered.
11/09/2019
Academia Omics
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Pharma CRO
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Analyst Software
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MultiQuant™ Software v2.0 Will Not Launch with a 2.0 License The MultiQuant™ software 2.0 license will not launch the 2.0 version of MultiQuant software. Instead, MultiQuant software 2.0.2, 2.1 or 2.1.1 must be installed.
10/03/2017
MultiQuant Software
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Direct LIMS Transfer in SCIEX OS Software Does Not Require a Template Transferring data to a LIMS system from a results table created in SCIEX OS software does not require a template. Once the results table is saved and locked, under the Reporting menu, select Transfer results to LIMS, and two LIMS export options will appear in the LIMS transfer dialog box.
11/07/2019
SCIEX OS
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How is the GETSTAT Function Used in SCIEX OS Software? The calculated columns for a processing method in SCIEX OS software allow users to add a formula that pulls the statistics pane calculations into the results table as a custom column. This can be done using the GETSTAT function.
04/01/2022
SCIEX OS
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How Does SCIEX OS Software Calculate the Ion Ratio for a Component? SCIEX OS software uses the regression parameter defined for the first component in the results table to calculate the ion ratio for all of the components in the results table.
11/03/2021
SCIEX OS
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Reporting Values for Calculated Concentration that Are Not Equal to N/A from a Results Table To filter results table data in a report based on the calculated concentration not equal to N/A, add the if statement $Calculated_Concentration<>"N/A".
12/04/2020
SCIEX OS
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Analyst Software
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MultiQuant Software
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What Is the Difference Between .wiff and .wiff2 Data Files? There are two data file formats for data sets acquired using SCIEX mass spectrometers: 1) .wiff and 2) .wiff2. Instruments using Analyst® software to acquire data will write data sets in the .wiff format. Instruments acquiring data using SCIEX OS software (version 2.0 or lower) will write data sets in the .wiff2 format. The newer versions of SCIEX OS software (version 2.1 and greater) write data in both the .wiff and .wiff2 format.
10/05/2021
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Shimadzu Pumps Do Not Start when Selecting Equilibrate in Analyst® Software Selecting Equilibrate in Analyst® software does not always turn on the Shimadzu LC pumps. To get the LC pumps to respond, users must follow a specific start up procedure and recognize when the system has gone into standby mode.
05/14/2018
Analyst Software
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How to Setup Standard Addition in SCIEX OS Software If the standard addition feature is enabled in SCIEX OS software, then the results table contains new columns, including Standard Addition Accuracy that compares the Standard Addition Calculated Concentration for a sample to the Standard Addition Actual Concentration. Standard addition is enabled in the quantitation method on the Integration tab under the Options menu.
11/04/2021
SCIEX OS
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Release Notes for Analyst® TF 1.7.1 Software with Components for LC Devices Analyst® TF 1.7.1 Software with Components for LC Devices Release Notes are attached. Please consult this guide for the newly added support for the NanoCell Interface, Exion LC series of devices and the Analyst Device Driver.
05/03/2018
Analyst Software
|
This article describes the different workflows for the iTRAQ® Reagents Application Kit - Protein (4374321) and the iTRAQ Reagents - 4plex or 8plex kits.
10/22/2020
Academia Omics
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Pharma CRO
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iTRAQ Reagent
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LC Methods Not Opening in Analyst® Device Driver Software Sometimes, the LC portion of a method in Analyst Device Driver (ADD) will not open successfully; yet the associated Analyst® software acquisition method file (.dam) is able to be opened, and the LC conditions can also still be viewed. To resolve this issue, avoid copying files between project folders or re-activate the hardware profile.
06/04/2018
Analyst Software
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What Are the Functions Available to Each Security Configuration Role in Analyst® Software? Individual users of Analyst® software can be assigned a particular role in Analyst software in the Security Configuration mode. The various roles are designed to limit a user's access to certain functions within the software depending on the role assigned. Below is a chart that shows how access to these functions decreases for the various default roles.
11/07/2019
Analyst Software
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Analyst® 1.7 Software Installation Error in Windows 10 Upgrading from Analyst® 1.6.3 to Analyst 1.7 software in a Windows 10 environment will cause an installation error, and Analyst 1.7 software will not launch. Analyst 1.7 with Hotfix 1 must be installed alone, and previous versions of Analyst software cannot also be installed concurrently.
03/14/2018
Analyst Software
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Data for Custom Calculations Show as Not Calculated on a Report In reports created from results tables in Analyst® and MultiQuant™ software, queries are used to compute the values for custom calculations, but occasionally the data appears as "Not calculated" on the report. This issue appears when the query file linked to the report template is not saved to the same folder as the report template.
10/11/2019
SCIEX OS
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Analyst Software
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MultiQuant Software
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How Are the Ion Ratio Flagging Rules Set Up in SCIEX OS 1.5 Software? To set up the ion ratio flagging rules in SCIEX OS software, select a processing method and then select edit. The rules can be changed under Flagging Rules and Ion Ratio Acceptance options under this menu.
08/08/2019
SCIEX OS
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LeadScape Software and LeadSampler (LS-1) Compatibility with Exion AD Pumps The Exion AD pumps sold by SCIEX are compatible with Sound Analytics' LeadScape software and the LeadSampler (LS-1) autosampler.
10/07/2019
Analyst Software
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Can I Do Any Data Processing in Keystone™ Viewer Software? No, Keystone™ viewer software provides data viewing capabilities only.
11/02/2021
Software
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Why Is There a .Special File Placed in the SCIEX OS Software Project Folders? SCIEX OS software creates a special placeholder file (with a file extension of .special) and places these files in the root of every known SCIEX OS project sub-folder. SCIEX OS software uses both the project folder names and the .special files to identify its known folders, and it will not recognize the folder if the .special files are removed.
09/26/2019
SCIEX OS
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Equilibration Issue with Exion and Photo Diode Array (PDA) and Analyst® Software When an Exion LC system with a photo diode array (PDA) detector will not communicate with the Analyst® software, reactivate the hardware profile and restart Analyst services.
12/11/2017
Analyst Software
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How to check Operating System Locale on Windows 7 SCIEX software is (unless stated otherwise in release notes) only supported on systems with a Locale of en-US United States. The process to accurately check your system locale is described below.
06/02/2016
Software
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The quantification algorithms for finding and integrating peaks in SCIEX software programs have improved significantly since the Analyst® software classic algorithm was introduced. Users of the SCIEX OS software will see two main advantages when integrating peaks with the new AutoPeak algorithm.
10/07/2021
SCIEX OS
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Analyst Software
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What File Formats Can Be Converted with the Newest Version of ProteoWizard Software? This newest version of ProteoWizard software, version 3.0.20258-97f41f698, can now convert files to the txt format, as well as the three original file types (MGF, mzML and mzXML). For SCIEX software users, the txt file might be a useful option; however, the quality of the output file from ProteoWizard has not tested.
11/06/2020
Academia Omics
|
Can the Pressure Trace Be Monitored or Saved in SCIEX OS 1.4 Software? Currently the pressure traces for many liquid chromatogram instruments can be monitored in real-time in the SCIEX OS software, but not be saved to a specific location.
10/16/2018
SCIEX OS
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Incorrect Argument Error when Adding Standards to a Results Table in SCIEX OS Software When adding multiple standard samples with the same name to a results table in SCIEX OS software, an error was generated: "Incorrect Argument. An item with the same key has already been added." This article explains the workflow that generates this error and provides a workaround.
10/22/2020
SCIEX OS
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When running the RackBuilder.exe, an error message is received: "Failed to open database AutosamplerPoetDb". This error can be cleared by setting the Windows User Account Control (UAC) settings to level 4 (Never notify) and then rebooting the computer.
05/14/2020
Analyst Software
|
For data acquired with the Echo® MS system, peak splitting is performed after acquisition is complete. If a subsequent batch is acquiring data to a file while the system is splitting peaks written to that file during the previous acquisition, then a resource conflict occurs.
11/03/2021
SCIEX OS
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QTOF Systems
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How to Adjust the Ion Ratio in MultiQuant Software Where are ion ratios modified in a MultiQuant software quantitation method (.qmethod file)?
05/21/2018
MultiQuant Software
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How Do You Convert a Non-scheduled MRM Method to a Scheduled MRM Method in Analyst? Converting a non-scheduled MRM method to a scheduled MRM method requires that the retention time of each transition is updated in the Analyst software method.
04/25/2017
Analyst Software
|
Setting Up Email Notifications and Emailed Reports in Cliquid® Software To set up email notifications in Cliquid® software, launch the software and select the User Profile option. To start email notifications and the option to have reports emailed, the user's email address will need to be entered in the user profile. |
How Very High Concentration Samples Are Handled in MPX 2.0 Software MPX™ 2.0 software contains a feature for automated carryover monitoring, which can identify samples above a certain threshold.
09/26/2019
MPX Software
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How to Save Application and System Event Logs in Windows 10 The Windows event logs often contain crucial data about the performance of SCIEX software. Follow these steps in Analyst® software to save your system and application event logs so that they can be analyzed by the SCIEX support team.
05/05/2022
Software
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Where Can I Find More Information about Software IQ/OQ Testing Plans? More information about software validation services can be found by emailing complianceservices@sciex.com.
06/09/2017
Pharma CRO
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Software
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How do I tell if the source exhaust is blocked or flooded? What is the cause and how do I fix it? Procedures to diagnose exhaust issues.
09/13/2017
Mass Spectrometers
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No, the loops, ForEachSample and ForEachVisibleSample, cannot be used within the same SCIEX OS software report template. Similarly, ForEachAnalyte and ForEachVisibleAnalyte cannot be used together in the same report template.
11/01/2019
SCIEX OS
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What Sample Plate Formats Are Supported on the Echo® MS System? The Echo® MS System is only compatible with specialized, acoustically clear microplates that were specifically designed to ensure the optimal and repeatable performance of droplet ejection. These specialized plates are available in both 384- and 1536-well formats.
05/04/2022
Pharma CRO
|
Software
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Missing Columns when Exporting the Protein Summary from ProteinPilot™ Software 5.0.2? This is a known issue in the ProteinPilot™ software 5.0.2 and was resolved with a patch.
04/16/2020
Academia Omics
|
Pharma CRO
|
ProteinPilot Software
|
Analyst® Software Error: Failed to Write Method to Datafile Caused by Symantic Antivirus Disabling the Sonar technology in the Symantic Antivirus program prevents the Analyst® software error "Failed to write method to datafile".
09/18/2017
Analyst Software
|
How to Print an Acquisition Method in Analyst® Software To print an acquisition method in Analyst® software directly from the .wiff file, open data file under the Explore mode and then click on the i icon in the toolbar for the data file's information. Activate the file info pane by selecting it, and then go to File > Print > Pane.
11/05/2020
Analyst Software
|
What Is the Correct Format for the Client License Text for Software Using a Concurrent License? To create and set up the license on the client PC for software using concurrent license server, the license text should be formatted as follows: SERVER [SERVERNAME.DOMAIN.COM or IP ADDRESS] ANY [PORT NUMBER] VENDOR ScxMSSW0 USE_SERVER
04/28/2020
Software
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Recommendations for Waters Driver Packs with Different Analyst® Software Security Modes When installing Analyst® software with the Waters' Driver Pack 4 (DP4) or the Driver Pack 4 supplemental release (DP4 SR1), consideration must be given to the Analyst security mode setting that is selected.
09/27/2019
Analyst Software
|
Searches of SCIEX libraries with the precursor mass tolerance set to 0.01 Da may not yield any hits. This is due to the fact that some of SCIEX libraries contain spectra that were acquired with inaccurate precursor m/z.
04/19/2019
SCIEX OS
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Unable to Add Users to the Security Database in Analyst® Software When Analyst® or SCIEX OS software is launched under the local admin account, an error message is received: “The current user is not added to the security database.” This error message appears because the software was originally installed under a non-admin account.
11/04/2021
SCIEX OS
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Analyst Software
|
If you receive warnings that your virtual memory is low youll need to increase the minimum size of your paging file
12/07/2016
Software
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MultiQuant™ Software Will Not Launch after Installation After successfully installing MultiQuant™ software and launching the software for the first time, the license activation screen does not appear and the license can not be installed.
06/21/2017
MultiQuant Software
|
Tips for Setting Up a Test in Watson LIMS™ Software for Use with Analyst® Software This article summarizes some helpful hints for setting up a test in Thermo Fisher™ Watson LIMS™ software for use with Analyst® software.
10/01/2019
Analyst Software
|
Changing the Extension on the Analyst® Software Data File Acquired to a Temp Folder If an Analyst® software data file is acquired to a temp or a cache folder, the data file may not have the .wiff or .wiff.scan file extension name. The data file extension name must be changed to .wiff or wiff.scan when the user attempts to move the files to a new location.
12/27/2018
Analyst Software
|
Where Are the Files Containing the Hardware Profiles Stored in Analyst® Software? The hardware profiles created in Analyst® software are stored in the API Instrument project folder in the Configuration sub-directory: C:\Analyst Data\Projects\API Instrument\Configuration.
10/30/2020
Analyst Software
|
How Is the ITC Parameter Accessed in Analyst® TF Software? Changing the ion transmission control (ITC) parameter in Analyst® TF Software helps to assess if the QJet® ion guide on a Triple TOF® system needs to be cleaned. This article explains how to access the ITC parameter within the Analyst software.
12/27/2018
Analyst Software
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QTOF Systems
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How To Create an Unsecured PDF Report in Sciex OS Software In order to create reports in SCIEX OS software in the portable document format (PDF) that are unsecured, the PDF setting in the SCIEX OS config file will need to be updated. Please follow below instructions to edit the config file.
03/20/2020
SCIEX OS
|
Where Can I Find Micro HILIC Columns to Separate Hydrophilic Peptides? Hydrophilic interaction chromatography (HILIC) columns for separating hydrophilic peptides can be found in the SCIEX column catalog (https://sciex.com/products/hplc-products/microlc-products/micro-hplc-columns).
08/03/2017
|
When ordering nucleic acid primers for use in either DNA sequencing or fragment analysis using the GenomeLab™ GeXP Genetic Analysis System or older CEQ genetic analyzers, be sure to select primers that--at the minimum--have been purified via solid phase extraction.
11/30/2018
GenomeLab GeXP Genetic Analysis System
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Can Biologics Explorer Software Be Installed on a PC with One Partition? Biologics Explorer software needs to be installed on a computer with both a C: and D: drive partition; however, it is also possible to install this software on a PC with just one (C: drive) partition if a patch is also installed.
01/24/2022
Academia Omics
|
BioPharmaView Software
|
Applying Results Table Column Settings to Another Results Table in SCIEX OS Software To apply the custom result table column settings from one Sciex OS software results table to another, open a results table in the Analytics mode. Then set the custom column order that you want to be displayed by clicking the More button, and then choose Table Display Settings.
02/15/2019
SCIEX OS
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Sciex OS Software Startup Always Defaults to License Activation Screen Every time Sciex OS software is launched, the license activation screen continues to appear with all fields blank, even though previous launches of the software indicate that the software license was installed successfully. Reinstalling the software as an administrator using a local admin user will resolve this issue.
09/20/2017
SCIEX OS
|
Preventing IP Address Conflicts with SCIEX 5500/6500+ Series MS and Waters' Acquity LC Instruments To eliminate the possibility of any IP address conflict, the Waters IP addresses should be changed when operating with a SCIEX 5500/6500+ series instrument. To change the IP address on a Waters' LC components, use the Waters DHCP configurator located in the following folder: C:\\Program Files\Waters Instruments\Waters DHCP Server Configuration.exe.
09/26/2019
Analyst Software
|
What Fields in DiscoveryQuant™ Software Standard Template Are Default Names? In DiscoveryQuant™ software version 3.0.2 and version 3.0.2 with HotFix 2, default names are generated for the sample, acquisition method, and data file name fields if they are not defined in the imported LIMS file.
11/03/2021
DiscoveryQuant Software
|
Protocols for Protein Precipitation in Samples before Using iTRAQ® Kits To prepare samples prior to iTRAQ® reagent labeling, use the following protocols.
05/01/2018
Academia Omics
|
Pharma CRO
|
iTRAQ Reagent
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Filtering Audit Trail Events Using a Set of Specified Criteria in SCIEX OS Software The audited events in the audit trail can be filtered using a set of specified criteria in SCIEX OS Software by selecting the Filter icon in the upper task bar on the Audit Trail screen.
11/06/2020
SCIEX OS
|
MultiQuant™ Software Report Error: Object Reference Not Set to an Instance of an Object If the MultiQuant™ software error "Object reference not set to an instance of an object" appears when creating a report, then the report template was not selected in the Create Report dialog. Check the file being used in the Report template field is a true report template. If not, replace it with a correctly formatted report template.
10/29/2019
MultiQuant Software
|
Where Is the Data Stored from a Photo Diode Array (PDA) Interfaced wtih Analyst® Software? When using a Waters photo diode array (PDA) with Analyst® software connected through an analog digital converter (ADC) connection, the data is stored in an Analyst data file (.wiff) and can also be viewed and processed in PeakView® software.
07/09/2018
Analyst Software
|
SQLite Exception Error in the Regulated Version of SCIEX OS Software While setting up the regulated version of SCIEX OS software (CFR features activated), the following error message appeared when accessing the Audit Map portion of SCIEX OS software: "System.Data.SQLite.SQLiteException : unable to open database file." To resolve this issue, change the Windows permissions so that the user has full access to Audit Trail files.
10/20/2020
SCIEX OS
|
How to Install Skyline Software on an Off-Line Computer To download Skyline software on a computer that is not connected to the internet, use the Unplugged installer or the Administrator installer:
03/20/2020
Academia Omics
|
Pharma CRO
|
Skyline Software
|
Tracking Pressure in Real-Time for an Exion LC System in Analyst® 1.7 Software The ability to access a real-time report of pressure versus time trace is not available in the Analyst® software for the Exion LC systems. So far, this feature is only available for Agilent LC systems when using the Analyst Device Driver.
12/28/2018
Analyst Software
|
Reporter Template Suite Software: The Summary Table Always Starts on the Second Page When a report is generated from a results table in MultiQuant™, Analyst® or SCIEX OS software, the summary table will only start appearing on the second page of the report, and the first page is left blank after the header. To resolve this issue, open the report template and select and highlight the summary table. In the Microsoft Word Layout menu, select Paragraph. De-select the option Keep with next.
11/14/2021
SCIEX OS
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MultiQuant Software
|
What Causes BioPharmaView™ Software To Stall when Processing Data or Running Batches? BiopharmaView™ software will stall when processing data when more than one instance of the software is open or if there are some corrupted files in the processing queue folder in the BioPharmaView program files folder.
03/21/2019
Academia Omics
|
Pharma CRO
|
BioPharmaView Software
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How To Provide Selective Access to Analyst® Software Projects To set access for select users at the project level in Analyst® software, the security configuration must be updated.
06/11/2020
Analyst Software
|
Reporter: Unable to Report Custom Columns Created in the Analyst® Software Results Table When a user creates a custom column in an Analyst® software results table and creates a report template using a custom tag for the custom column, the data for this custom column is not output to the report. The report template will not read the custom column unless [Custom] is added to the column name in the results table
11/04/2021
Analyst Software
|
Custom Calculations and Flagging Rules for Carryover in SCIEX OS Software This article contains instructions on how to set up a new processing method in SCIEX OS software that has the custom calculations and flagging rules for carryover.
11/04/2021
SCIEX OS
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Why Do I Receive Memory Concerns Warning when Processing Data in MultiQuant™ Software? When processing a large data set in MultiQuant™ software 3.0.3, users may see a Memory Concerns message, "The Results Table you opened may cause out of memory computer issues. To free-up memory close other applications and any other opened results table." This message is a warning, not an error message, regarding the amount of memory required to process and display a large data set.
10/22/2020
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MultiQuant™ Software: Concentration Upper Limits Flag Incorrectly Assigned when No Peak Detected In Multiquant™ software using a quantitation method with upper limits for concentrations set causes samples with N/A for peak area to be flagged for concentration.
09/16/2022
MultiQuant Software
|
Reporter 3.2: Adding Custom Columns to a Report Template Custom columns can be added to a report template so that custom data values values can be read into a report created with Analyst® Reporter 3.2 (via Analyst software).
02/28/2019
Analyst Software
|
Disulfide bond mapping in BioPharmaView™ software is described in the user guide. However, creating a disulfide bridge table in addition to analyzing cysteine modifications simultaneously is not described and cannot be done.
02/26/2018
Academia Omics
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Pharma CRO
|
BioPharmaView Software
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Is There an Equivalent to Single User Mode in SCIEX OS Software 2.0? Single user mode is a security mode in Analyst® software that allows for any user that is logged in to a PC using any Windows account to access the software as an administrator. However, there is not currently an equivalent to single user mode in the SCIEX OS software. The security mode options in SCIEX OS software are limited to integrated mode and mixed mode.
11/05/2020
SCIEX OS
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Analyst Software
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Do you have any recommendations for the inclusionexclusion lists size for the Analyst TF 1.6 software
07/08/2016
Analyst Software
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How To View Metric Plots in the Analytics Mode in SCIEX OS Software To view trends (such as internal standard peak area) over a range of samples in a results table, a metric plot can be created in the Analytics mode of SCIEX OS software by selecting the column with the values of interest and then selecting Create metric plot from the More menu.
10/14/2022
SCIEX OS
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How To Change Results Table Peak Review Settings in Analyst® Software While reviewing a results table in the Quantitate mode of Analyst® software, the peak review settings can be changed to view more than one chromatogram and to adjust the x-axis and y-axis automatic zoom settings.
09/30/2022
Analyst Software
|
Getting Started with OneOmics™ Suite 3.4 This article describes the required registration, browser setup, software setup, and first steps for uploading data to the Data Store in the web-based and cloud-powered OneOmics™ suite.
03/03/2023
Academia Omics
|
Software
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This article provides some guidance for using a secure network account (SNA) with SCIEX OS software or a special acquisition account (SAA) with Analyst® software.
12/13/2021
SCIEX OS
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Analyst Software
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Setting Up MRM Transitions if Q1 Mass Is Identical to that of a Second Compound To set up a MRM transitions where the Q1 mass for one compound is identical to a second compound in Analyst® software, change the Q1 mass of the second compound by 0.1 -0.05 Da. After making this adjustment, the software will accept the duplicate mass for Q1.
05/31/2018
Academia Omics
|
Environmental Industrial
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Food and Beverage
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Pharma CRO
|
QTRAP Systems
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Triple Quad Systems
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The patch, DiscoveryQuant™ 3.0.2 Patch for Scrollbars and Plot Resize Issue, needs to be installed to resolve the TIC plot not resizing when using DiscoveryQuant software 3.0.2.
11/03/2021
DiscoveryQuant Software
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What Is the Exact Mass that iTRAQ® Reagents Add to Peptides? SCIEX does supply the masses of the labels in the iTRAQ® Reagent 4plex and 8plex kits, but masses with more significant figures can be found at www.unimod.org.
12/18/2019
iTRAQ Reagent
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What SCIEX Mass Spectrometer Data Files Work with Keystone Converter Software? Keystone Converter Software can convert nominal mass (.wiff1) files, but it does not work with SCIEX OS software files or TripleTOF system files.
11/02/2021
Software
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How Is the Full Screen Option Enabled in SCIEX OS Software? Select the Full Screen Mode option to use SCIEX OS as the primary application. Users cannot close the software or access other software programs.
11/04/2021
SCIEX OS
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Can I Install SCIEX OS and Analyst® Software on the Same Computer for Data Acquisition? Analyst® software and SCIEX OS software can be installed on the same PC, but SCIEX does not support workflows that use both the Analyst and SCIEX OS software to acquire data from the same mass spectrometer.
03/03/2023
Software
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The Central Admin Console (CAC) software can support 100 client workstations with the SCIEX OS software installed.
09/16/2022
Pharma CRO
|
Software
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Verifying if the Data File is Acquired with Checksum On or Off in Analyst® Software After opening a data file in Analyst® software in Explore mode, select the Verify Checksum radio button; a new window will appear to indicate whether or not the checksum feature has been turned on for the data file.
11/09/2018
Analyst Software
|
When installing the Analyst® Device Driver with Analyst® software, the order of installation of the programs is important. The Analyst software must be installed first, and then the Analyst Device Driver is installed next.
10/04/2019
Analyst Software
|
What Is the Best Way to Back Up My Library Compounds in LibraryView™ Software? This article provides some guidance on best practices for backing up your library compounds stored in LibraryView™ software. Its recommended that a snapshot is created of the library every time the library is updated or edited.
04/28/2020
LibraryView Software
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Common Project Area Folder Write Access Error in SCIEX OS Software When creating a new project in SCIEX OS software, the following error was received: The current user does not have write access to the requested project. This issue was resolved by copying the common-project-area folder in the SCIEX OS Data folder over from a different PC with an intact root directory.
03/06/2020
SCIEX OS
|
Analyst® Software Freezes when the Hardware Profile Includes a LC System In situations where Analyst® software will only launch acquisition methods successfully with a MS-only hardware profiles, but crashes when a Shimadzu LC autsaompler with a rack controller is added to the hardware profile, check to see if the Rack Controller is checked on the autosampler portion of the hardware profile.
05/11/2018
Analyst Software
|
Agilent Infiniti II HPLC System and SCIEX 6500+ Systems When an Agilent Infinity II HPLC system is experiencing difficulty communicating with a SCIEX QTRAP or TripleQuad 6500+ System while running samples, this procedure must be followed for bringing the HPLC system online and building methods.
03/24/2017
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Cliquid Error Retrieving the COM class factory for component with CLSID Cliquid will run samples successfully but will be unable to process them and will report Error Retrieving the COM class factory for component with CLSID 36977493A67011Dc8Dcc00104BC5f89A at the bottom of the window.
06/02/2016
Cliquid Software
|
Recovering a Lost or Corrupted Acquisition Method in Analyst™ Software To recover or recreate an acquisition method that was lost or corrupted in Analyst™ Software, click in the information pane of an older data file, and then right click and choose Save Acquisition Method.
10/30/2020
Analyst Software
|
How to Group Analytes in an Analyst® Software Results Table To place multiple analytes (or multiple transitions for the same analyte) into a group within a results table in Analyst® software results table, follow the steps outlined in this article.
03/20/2020
Analyst Software
|
Waters Driver and SCIEX Software Compatiblity Guide Please consult the attached guide, "Waters tested Sciex Configuration Guide," to determine if a Waters driver will work with a particular version of Analyst® software. Please make sure Waters UPLC firmware is compatible with the driver pack or ICS version.
05/08/2018
Analyst Software
|
Adding an Arrow in MultiQuant™ Software to Display the Expected Retention Time during Peak Review In MultiQuant™ software, an arrow can be added to the peak review chromatogram window to represent the expected retention time. To do this, right click within the peak review pane and select Options from the list. A Peak Review Options popup window will appear. Check the option Mark Expected RT with Arrow under the Appearance tab. Then select OK.
10/29/2020
MultiQuant Software
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MultiQuant™ Software Error: "Update Column Settings Failed" The MultiQuant™ software error "Update Column Settings Failed. Object reference not set to an instance of an object" is due to a memory leak problem, which can be quickly fixed by closing and reopening the program.
12/13/2017
MultiQuant Software
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How to merge Analyst Acquisition Methods Where to find, how to install and to use the 'Merge MRM' Script in Analyst.
05/31/2017
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Declustering is achieved with the SCIEX Triple Quad 7500 system using a voltage differential between the QJet® ion guide and the IQ0 lens or a voltage differential between IQ0 and Q0 (the quadrupole ion guide before Q1). This article explains how Q0 dissociation is achieved using simple or enhanced modes in the SCIEX OS software and how the D Jet™ ion guide is involved in enhanced-mode dissociation.
06/22/2022
SCIEX OS
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Triple Quad Systems
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Can MarkerView™ 1.3 Software Import T2D Files from the TOF/TOF™ Series of Instruments? MarkerView™ 1.2.1 and 1.3 software and PeakView® 2.2 software can import T2D files generated on the TOF/TOF™ series of instruments.
02/26/2018
Academia Omics
|
MarkerView Software
|
To configure Data Innovations' instrument manager system with the SCIEX LIMS transfer license, SCIEX software users must contact Data Innovations, not SCIEX, for assistance with the data transfer setup. Users who purchased the LIMS license for SCIEX OS or MultiQuant™ software will need to reach out to Data Innovations directly by emailing your region’s specific sales group. This will allow Data Innovations to track your request and provide a response within 48 hr.
10/30/2020
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How Can I Tell if Zeno SWATH Pulsing Is Working Correctly on My ZenoTOF 7600 System? To verify that Zeno SWATH pulsing is working on a ZenoTOF 7600 system, users should run a SWATH® acquisition method with and without additional Zeno pulsing using standards from the SWATH acquisition performance kit.
12/16/2022
Academia Omics
|
Pharma CRO
|
Creating Windows User Groups for Analyst® Software Security Configuration Windows User Groups are established for each role established in the Analyst® software security configuration.
03/08/2018
Analyst Software
|
Multi-Page Printing Subsequent pages identical to the first. A corruption in the local user profile can cause Analyst to print pages incorrectly with multipage documents having all pages as the first.
06/02/2016
Analyst Software
|
Can the ChemoView™ Software LIMS Template Be Edited? Yes, the LIMS template for ChemoView™ software can be edited and customized. Once changes are saved in the report template, the report output will reflect the changes.
10/10/2019
ChemoView Software
|
ProteinPilot™ Search Error: Unhandled Exception: Out Of Memory Exception During a search with ProteinPilot™ Software 5.0, 5.0.1 and 5.0.3, the error "Unhandled Exception: Out Of Memory Exception" appears. This issue is due to the LC/MS reconstruct crashing within the ProteinPilot Software when data sets with a high MS1 scan speed are being processed.
11/06/2020
Academia Omics
|
ProteinPilot Software
|
Creating a New Report Style in Cliquid® Software To create a new report style in Cliquid® software, go to the Administrator Tasks (Home) menu, then select Manage Report Styles and Create a Report Style.
10/10/2019
Cliquid Software
|
SCIEX Software Activation with Offline Workstation How to activate Analyst, MultiQuant or SCIEX OS software with a computer which is not connected to the internet
11/19/2018
Software
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Converting WIFF2 Files from SCIEX OS Software to the mzML and mzXML Format The ProteoWizard tool (http://proteowizard.sourceforge.net/downloads.shtml) for mzML and mzXML conversion has been updated to work with the WIFF2 files that are produced by SCIEX OS software.
05/17/2022
Analyst Software
|
How Are the Correct Solenoid Valves for a Shimadzu Pump Added to an Analyst Hardware Profile? The solenoid valves for Shimadzu pumps can be set up by editing the hardware profile and changing the pump configuration.
06/01/2017
Software
|
How Is the Peptide Score Calculated in BPV Flex™ Software 2.1? The BPV Flex™ Software 2.1 peptide score indicates the probability that the peaks in a given MS/MS spectrum will match those of the theoretical peptide fragments by random chance. Therefore, the score calculation is derived from observed MS/MS fragments and the corresponding intensities, as well as the number of theoretical MS/MS fragments.
03/31/2021
Academia Omics
|
Pharma CRO
|
BioPharmaView Software
|
How Can an Ion Library Group File Generated by ProteinPilot™ Software Be Uploaded to BaseSpace? The procedure for uploading a group file generated by ProteinPilot™ software is described here. The group file is used as an ion library in BaseSpace and is uploaded using the CloudConnect MicroApp within PeakView® software.
08/03/2017
Academia Omics
|
PeakView Software
|
A regular expression (regex), also called a rational expression, is a sequence of alphanumeric and/or special characters that can define a search pattern depending on their context.
10/30/2020
|
Does SCIEX OS Software Have Functionality To Help My lab Achieve Compliance with Regulations? Yes. SCIEX OS software has all the key data integrity features required to reduce your regulatory risk, including configurable security, electronic signatures, and audit trails.
11/02/2021
SCIEX OS
|
Analyst® Software: How to Increase the Number of Waiting Samples in the Queue By default the number of samples that can be submitted from the Analyst® Software queue is 100 samples. To change the number of waiting samples shown in the queue, select the Configure mode, and then navigate to the Tools menu. Select Settings and then Queue Options. Type in a desired number for Max Num Waiting Samples, and then click OK.
12/02/2020
Analyst Software
|
During PPG Tuning Some Mass-Charge Ratios Appear as NA While tuning and calibrating the MS in Analyst® software, some masses in the calibration table are showing up as NA in the table despite clearly being present.
10/19/2018
Analyst Software
|
How to Backup or Move Masterview Libraries How to Backup or Move Masterview Libraries
12/07/2016
Environmental Industrial
|
Food and Beverage
|
Forensics
|
MasterView Software
|
Should I Install Windows Updates on My Acquisition Computer? Windows updates should not install automatically on your acquisition workstation, but once you receive notification that there are new updates, these can be installed when Analyst® software is not acquiring data.
09/12/2017
Software
|
Trouble Importing Sample List into Lipidomics Workflow Manager Project In order to import a sample list successfully into Lipidomics Workflow Manager 1.0.5, the following software must be also installed: Microsoft Office 2010 and Access 2007 Runtime.
05/25/2017
Software
|
DiscoveryQuant Cannot set spectrum for experiment X DiscoveryQuant Optimize will not complete optimization with the error message Cannot set spectrum for experiment followed by a number which can be any one of your scan functions.
10/01/2015
Pharma CRO
|
DiscoveryQuant Software
|
How to Check if Unknown Samples Are Within Calibration Curve Range in SCIEX OS Software To check if unknown samples are within the calibration curve range in a SCIEX OS software results table, additional calculated columns will need to be added to the results table.
12/05/2021
SCIEX OS
|
Manage Mode Is Greyed Out in ChemoView 2.0.3 Software After logging into ChemoView software, only the Process pane was accessible. The Manage pane was greyed out. This was resolved by changing all users in Analyst software to administrators in the Security Configuration mode.
10/20/2017
ChemoView Software
|
Can ethanol be substituted for isopropanol when performing iTRAQ protocol for 4Plex and 8Plex Can ethanol be substituted for isopropanol when performing iTRAQ protocol for 4Plex and 8Plex
10/07/2016
Academia Omics
|
iTRAQ Reagent
|
Incorrect Argument Error when Creating MultiQuant™ Software Results Table To resolve the Incorrect Argument error that occurs when creating a MultiQuant™ software results table, data should be transferred within the Analyst® software project folder to a new PC and not as individual .wiff and .wiff.scan files.
09/26/2017
MultiQuant Software
|
How Can Library Hit Results Be Filtered by Score in a SCIEX OS Software Results Table? To filter library hit results in a SCIEX OS software by library score and to remove any results without a proper score (presenting with N/A), a custom filter can be used in the Analytics mode.
10/02/2019
SCIEX OS
|
Chromatograms do not populate on printed reports linked image cannot be displayed When generating large reports after a number of Chromatograms the box will be filled with the text linked image cannot be displayed
07/08/2016
Analyst Software
|
No, the E Lens™ Technology integrated into the SCIEX Triple Quad™ 7500 LC-MS/MS System has been designed for electrospray ionization (ESI) mode of analysis and is not compatible with atmospheric pressure chemical ionization (APCI).
11/06/2020
|
Generating a Service Package in Sciex OS Software To generate a service package in Sciex OS software that contains the event logs, select Configuration, About, and Generate a Support Package.
01/15/2024
SCIEX OS
|
Resolving the PeakView™ 2.2 and MultiQuant™ 3.0.3 Software Error after Upgrading to .NET 4.7.2 After upgrading PeakView™ software to version 2.2 or MultiQuant™ software to version 3.0.3, the following error message was generated: "The procedure entry point nextafterf could not be located in the dynamic link library MSVCR120_CLR0400.dll." The workaround is to remove .NET Framework 4.7.2 and then install the .NET 4.0 software.
09/26/2019
MultiQuant Software
|
PeakView Software
|
Will ProteinPilot™ 5.0.2 Software Function on a Windows 7 64-Bit System? ProteinPilot™ 5.0.2 software has only been tested on Windows 10 SP1 64-bit with Microsoft Office version 2016.
10/17/2018
Pharma CRO
|
ProteinPilot Software
|
What Are the Reasons for Hybrid Electrodes Probe Blockage? Common issue reported with hybrid electrodes probes.
05/15/2018
Academia Omics
|
Mass Spectrometers
|
Top 10 des bonnes pratiques de l’utilisateur pour minimiser les contamination des systèmes LC/MS French Translation of Knowledge Article 000017896
06/21/2021
|
Scheduled MRM not supported in Multiquant you do not have the required license to open files containing scheduled MRM data
07/08/2016
MultiQuant Software
|
Removing Rows Releated to Internal Standards from a MultiQuant™ Software Table If its not desirable to view the internal standard information in a MultiQuant™ software results table, de-select the IS button by clicking on the binoculars icon in the Components & Groups column.
05/14/2020
MultiQuant Software
|
How Inclusion or Exclusion Lists Are Imported into Analyst® TF Software This article describes how a text file can be created to import an inclusion or exclusion list into Analyst® TF software when building an IDA method.
11/06/2020
Pharma CRO
|
Analyst Software
|
Keystone™ viewer software displays an AnIML file, including those that were not created by Keystone converter software.
11/02/2021
Software
|
Reporter 3.2: Including Only the Results for the Quantifier Ion in a Report To include only the data associated with the quantifier ion in a report, group the quantifier and qualifier ion for a particular analyte, and then use the For Each AnalyteGroup loop around the information to be reported.
11/09/2019
SCIEX OS
|
Analyst Software
|
MultiQuant Software
|
Acquity AAO Service Did Not Start Steps are provided for editing the service properties of the AAO file to resolve the error "Cannot start service from the command line or a debugger." Editing the service properties will direct the AAO file to reopen in the event that it closes.
12/11/2017
Software
|
CAD Gas Setting Displays Incorrectly in the File Information for Analyst® 1.6.x or Higher If a data file was acquired using simplified CAD gas settings and opened in the Analyst® software without the correct hardware profile active, the CAD gas setting in the file information will be displayed incorrectly.
06/01/2018
Analyst Software
|
If data is acquired with one version of SCIEX OS software, and then data is appended to the data file (.wiff) with another version of SCIEX OS software, then the software version recorded in the data file is incorrect. The earlier software version will be shown in the File Info section, and the newer version will not be captured in the file information.
11/03/2021
|
File Locking Prevents Addition of Remaining Injections to Existing Analyst® Software Data Files To add injections to an existing data file, ensure that the Analyst® software data file is not in use or locked by another software program.
10/04/2019
Analyst Software
|
The Peakfinding Algorithm in SimGlycan® Software Improves Search Results on SCIEX Datasets The Peak Detection & Picking feature in SimGlycan® software versions 5.9.2 and higher offer an improved peak-picking algorithm that is faster and more efficient at handling data from SCIEX TripleTOF® LC-MS/MS System instruments.
11/12/2019
Academia Omics
|
SimGlycan Software
|
License File Was Not Emailed when AID Key Was Entered without Dashes When activating a software license key online (at https://licensing.sciex.com/), the license key number must be entered with dashes after every fourth character in the AID- key (e.g., AID-xxxx-xxxx-xxxx-xxxx-xxxx-xxxx-xxxx-xxxx).
07/14/2017
|
Plate Template Used for Tissue Imaging on MALDI TOF/TOF Instruments? To use the Mass Spectrometry Imaging Starter Kit design by LaserBio Labs™, your tissue needs to be mounted onto a blank LC MALDI plate. This blank MALDI plate fits a 123 mm x 81 mm plate holder. A starter template is provided here to create a customized plate for MALDI data acquisition.
10/08/2018
Academia Omics
|
Error Message for National Instruments GPIB Driver Received during Analyst® Software Installation To resolve the error message received for the National Instruments GPIB driver during Analyst® software installation, install the driver from the GPIB folder on the Analyst software installation disk manually.
05/21/2018
Analyst Software
|
How do I debug MultiQuant Queries Often when developing MultiQuant queries it can be useful to see the calculations which are performed during the query. By setting MultiQuant queries to debug mode you can view the files generated in excel allowing you to fix any errors in the calculations
12/22/2015
MultiQuant Software
|
How Many Vials of Each iTRAQ® Reagent Are in the Multiplex Kit? Each iTRAQ reagent multiplex kit (PN 4352135) contains 5 vials of of the following iTRAQ reagent labels: 114, 115, 116, and 117.
02/26/2018
Academia Omics
|
Pharma CRO
|
iTRAQ Reagent
|
This article gives a guidance how to change the typical sample used in MultiQuant software
09/04/2016
MultiQuant Software
|
Why doesn't a TrEMBL FASTA file work for a ProteinPilot search? This is a known issue, and the TrEMBL database is not recommended for use with ProteinPilot software. The TrEMBL database is automatically annotated and not reviewed and could contain redundancies in terms of protein sequences, protein ascension numbers, etc.
03/21/2017
Academia Omics
|
ProteinPilot Software
|
Exporting reports and data graphic from the 32Karat method Procedure to export reports (e.g. % area report, etc.) and data graphics (electropherograms with annotations) from the method.
04/05/2019
PA 800 Plus Pharmaceutical Analysis System
|
Injection volume must be a positive value If the Regional Settings in an Acquisition Computer with Analyst® Software is not set to US English , this can course the Error message: "Batch not submitted-Injection volume must be a positive value" during submitting a Batch.
10/23/2017
Mass Spectrometers
|
Analyst Software
|
What Software Is Supported for Analysis of Data from the Echo® MS System? Once data collection from a well plate has been completed on the Echo® MS System, a .csv file is created for each well, in addition to another file that contains all of the data from the well plate. The .csv files can be imported into any data visualization software for further analysis, or the .wiff2 data can also be reviewed in SCIEX OS software. The data set contains the sample name, well location, component name, peak area, peak height, and peak width.
10/19/2020
|
MultiQuant™ Software Error: Currently Running in Another Windows Session To resolve the MultiQuant™ software error "Currently running in another Windows session on this computer. Switch to the other session and close the software", shut down Analyst® and MultiQuant software and services under both accounts, and then relaunch software under one account.
03/07/2018
MultiQuant Software
|
How to Export Results for Specific Analytes from SCIEX OS Software To report only the results for specific analytes from SCIEX OS Software, a results table will first need to be opened in the Analytics mode. Start by selecting one of the analytes of interest from the Components and Group Tab. If multiple analytes need to be reported, then select additional analytes by holding the Ctrl key down and selecting each additional analyte with the mouse. Then in the Reporting menu, select Export Results > Export and Save Results Table.
11/10/2021
SCIEX OS
|
Using the 25 Micron ESI Electrode with the DuoSpray™ Source? A 25 micron ESI electrode can be used with the IonDrive™ Turbo V source and the DuoSpray™ source.
10/17/2018
Academia Omics
|
Pharma CRO
|
Mass Spectrometers
|
How Many User Roles Are Available in ChemoView™ Software? ChemoView™ software supports two user roles, technician and administrator. Each role allows access to different rights and functions within the software.
09/25/2019
ChemoView Software
|
How to Generate MRM Ratios in Analyst Software This is a known issue in the ProteinPilot™ software 5.0.2 and was resolved with a patch.
03/02/2018
Clinical
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Environmental Industrial
|
Food and Beverage
|
Forensics
|
Pharma CRO
|
Software
|
Reporter Error: Cannot Retrieve Analyte: the Specific Index ("-1") Is Out of Range If the following error is received when creating a report for a results table in MultiQuant™ or SCIEX OS software "Cannot retrieve analyte: the specific index ("-1") is out of range", ensure that the individual tags within the loop are for the same sample type (e.g., use internal standard tags if For Each Internal Standard is used for the loop).
11/22/2021
SCIEX OS
|
Calculating the Theoretical Average Mass for an Intact Protein in BioPharmaView™ Software BioPharmaView™ software uses the isotopic masses published by NIST online at: https://physics.nist.gov/cgi-bin/Compositions/stand_alone.pl. Please note that the results generated will be the same throughout all SCIEX software (e.g., PeakView™ and ProteinPilot™ software).
08/09/2019
Academia Omics
|
Pharma CRO
|
BioPharmaView Software
|
Where Are the Report Templates for BioPharmaView™ Software Stored? The file folder locations of the report templates for BioPharmaView™ software are listed in this article.
03/20/2020
Academia Omics
|
Pharma CRO
|
BioPharmaView Software
|
How do I store iTRAQ® labeled peptides? Store iTRAQ® reagent labeled peptides at -20 or -80 degrees Celsius. Avoid having the peptides undergo multiple freeze/thaw cycles. iTRAQ-labeled peptides can degrade over time.
04/07/2017
Academia Omics
|
Pharma CRO
|
iTRAQ Reagent
|
Can a Method Built in MPX™ Software Be Converted to a Method Used with SCIEX OS Software? No, methods built in MPX™ software cannot be converted for use in SCIEX OS software. Files built in MPX software are not supported in SCIEX OS software. |
Altering Parameters in PPG Tuning Methods Causes Mass Shift and Resolution Issues Changing any of the source or compound parameters in a PPG tuning method (such as Q1PosPPG.dam located in the API Instrument project folder in the Analyst Data folder) causes mass shift and resolution issues in the resulting data file.
04/30/2020
Analyst Software
|
How to Generate a Service Package in Analyst® Software Generating a service package allows the technical support team to pinpoint and resolve software issues more quickly. To diagnose an issue with Analyst® software, download and install the Analyst Diagnostics Tool (ADT).
05/06/2022
Analyst Software
|
Finding the Archived Results in Chemoview™ Software All result reports are archived in Chemoview™ software in the Results Archive tab. Users can browse the report by job date, or search job by date, .wiff file name and sample name.
09/23/2019
ChemoView Software
|
Can You Print a Quantitation Method in MultiQuant™ Software? MultiQuant™ software does not have an option to print the quantiation method. However, the quantitation method can be copied or exported as text file into Excel and printed.
06/06/2017
Software
|
What Are the Peptide Sequences in the Six-Peptide Mixture (PN 4465940)? The six-peptide mixture (part number 4465940) is used for the calibration of mass spectrometers. The kit contains the following six peptides and their mono-isotopic masses: bradykinin (2-9 clip) (904.4681), angiotensin I (1296.6853), glu1-fibrinopeptide (1570.6774), ACTH (1-17 clip) (2093.0867), ACTH (18-39 clip) (2465.1989), and ACTH (7-38 clip) (3657.9294).
12/26/2018
Academia Omics
|
Pharma CRO
|
Standards and Reagents
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Installing SciexOS 1.4 on a PC where Other SCIEX Software Was Previously Installed SciexOS 1.4 uses the LibraryView™ Framework in the background to manage libraries and library searching. Older versions of the framework may be on the PC that can interfere with the installation of 1.4. Also, older version of Microsoft SQL server and .NET Framework can cause the installation process to fail. This article contains information on steps to take to remove older versions of the aforementioned tools.
07/02/2018
SCIEX OS
|
Why it is not recommended to open Audit Trail Archives with Newer Versions of Software Opening/reading Audit Trail files should only be performed with the same version of Analyst software as they were acquired.
09/04/2016
Analyst Software
|
What Integration Algorithms Are Used by SCIEX OS Software? The SCIEX OS software has three integration algorithms that can be used to integrate peaks, and these options are listed in the Project Default Settings in the Analytics module: MQ4, AutoPeak and Summation.
10/22/2019
SCIEX OS
|
Common Issues when Using 32 Karat Software for Peak Integration Peak integration with the 32 Karat software can be improved using the suggestions found here.
11/30/2018
PA 800 Plus Pharmaceutical Analysis System
|
How Does the Quadrupole Transmission Function in the TripleTOF® Systems Work? For TOFMS, all ions pass through Q1 in RF mode. In general, Q1 and Q2 perform "hops" over the mass range, ensuring an appropriate envelope of masses is passed into the TOF analyzer. The general explanation found here for the QSTAR® systems can also be used to explain TripleTOF® systems as well.
01/31/2018
QTOF Systems
|
Switching between Analyst® and SCIEX OS software for acquisition, either on the same or different computers, is not a supported workflow.
05/18/2022
Academia Omics
|
Clinical
|
Environmental Industrial
|
Food and Beverage
|
Forensics
|
Pharma CRO
|
Software
|
Can the SCIEX OS Software Central Administrator Console (CAC) Run on a Citrix Server? The SCIEX OS Software Central Administrator Console (CAC) should run on a Citrix Server, but this configuration has not been tested and is not officially supported.
10/12/2022
Pharma CRO
|
Software
|
How Does the Score in the Peptide Sequencing Section of BioPharmaView™ Software 2.1 Work? Each peptide is displayed in a table after processing the peptide digest in BioPharmaView™ software. A score is given to each peptide after it is compared to the theoretical proteolytic digest.
12/01/2017
Academia Omics
|
Pharma CRO
|
BioPharmaView Software
|
This article describes the cause of this Event which can effect network acquisition
06/02/2016
Analyst Software
|
Re-installing a MPX License by Dropping the License Directly into the Program Files If MPX driver software does not accept a license saved on the desktop during the license installation process, drop the license into the MPX bin folder in the program files.
03/31/2017
MPX Software
|
How to Access the SCIEX OS Software Help Menu To access the SCIEX OS software help menu, click on the question mark in the upper, right-hand corner.
10/16/2019
SCIEX OS
|
How To Enable the New Intact Protein Quant Feature in SCIEX OS 1.7 Software The Intact Quant feature in Sciex OS 1.7 software platform enables the quantitative processing of intact proteins without sample prep and allows for the complete and compliant intact reconstruction of protein data sets. To activate this feature, an additional, add-on software license, SCIEX OS IntactQuant 1.7 (part number 5078597), must be installed in the C:\ Program Files\SCIEX\SCIEX OS folder.
03/17/2020
Academia Omics
|
Pharma CRO
|
SCIEX OS
|
Where Can I Download SCIEX Software? Full versions of many our software programs can be downloaded from the SCIEX website at https://sciex.com/software-support/software-downloads.
03/16/2018
Software
|
How To Reset a QTOF System Mass Spectrometer Power cycling a QTOF mass spectrometer can help resolve communication issues. The The TripleTOF® system, the X500 QTOF system, and the ZenoTOF system instruments (X500-, 5600-, 6600- and 7600-series instruments) are all reset in the same way. This article describes the reset procedure for these instruments.
02/25/2022
QTOF Systems
|
How Do You Obtain a Token for ChemSpider Software? The Formula Finder Settings panel in Sciex OS software requests a ChemSpider security token after selecting the ChemSpider Service. To obtain a token, users will have to register on the ChemSpider website.
11/08/2017
SCIEX OS
|
MarkerView 1.2.1 error Could not get method information for A1_MS_1.t2d when trying to download data MarkerView 1.2.1 error Could not get method information for A1_MS_1.t2d when trying to download data
07/08/2016
Academia Omics
|
MarkerView Software
|
How Do I Activate My SCIEX License Key? To activate a SCIEX license key, log into www.sciex.com with your username and password. Navigate to https://sciex.com/support/activate-software and complete the required fields.
01/24/2019
Software
|
Reporter Templates Cannot Be Edited Due to Missing XML Tags When opening a template, an error was received from the Template Content Control Manager, "Error: Specified argument was out of range of valid values." To resolve this error, the Template Content Control Manager needs to be reinstalled.
11/04/2021
SCIEX OS
|
Analyst Software
|
MultiQuant Software
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Adding Negative Ion Mode Experiment Information to Analyst® Software Quant Methods Adding a negative ion mode experiment to an Analyst® software quantitation methods can be done by opening an older quantitation method in Analyst and then using Save As to save a copy of the older method. The negative ion mode information can be added by toggling the Data Source options in that drop down menu.
05/31/2018
Analyst Software
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Differences between “Find Any” and “Find” in FormulaFinder in SCIEX OS Software In SCIEX OS software, the “Find Any” function in Formula Finder considers just the monoisotopic peak to be within the m/z tolerance. Both odd (in italics) and even electron elemental compositions are provided. When using “Find Any” element ranges “From” and “To” are considered. The “Find” function in Formula Finder uses all constraints, including the mass tolerance for all selected peaks in the isotope pattern and the settings from the Options dialog.
10/22/2020
SCIEX OS
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How Do You Set Up for Manual Tuning Using Tee Infusion? Before setting up your manual tuning method for source/gas optimization, your MS instrument must be set up for continuous infusion with high LC flow.
10/13/2017
Mass Spectrometers
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How Does the Size of a Converted AnIML File Compare to the Original Wiff File Size? The converted AnIML file created using the Keystone™ converter software is 1.6 to 1.8 times bigger for data sets with multiple reaction monitoring (MRM) data. This is because the original .wiff.scan file is compressed, but then it is uncompressed as part of the conversion and storage process when creating the AnIML file.
11/02/2021
Software
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A MS acquisition method built in Analyst® software cannot be opened directly in SCIEX OS software 2.2, but it can be converted to a usable MS method in SCIEX OS software using the Convert file feature in the MS Method workspace.
04/01/2022
Academia Omics
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Clinical
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Environmental Industrial
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Food and Beverage
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Forensics
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Pharma CRO
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Software
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Can the Eksigent Nano III ion source fittings withstand the back pressure when using a UPLC Can the Eksigent Nano III ion source fittings withstand the back pressure when using a UPLC
10/07/2016
Academia Omics
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NanoLC 400
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The ExionLC 2.0 System Status Icon in the Analyst®Software Is Red But Shows as Ready Sometimes when an error occurs on the ExionLC 2.0 system, the LC status icon in the Analyst® software turns red — but the LC status may be listed as Ready. To reset the LC system, deactivate the hardware profile and then activate it again.
11/03/2021
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Differences in Date-Time Stamp for a Results Table Audit Map in Analyst® Software In the Audit Trail Manager in Analyst® software, the audit map associated with a Results Table (accessed under the Results Tables node) might have a modified date-time that is different than the modified date-time shown with the project node (accessed under the Projects node) or in a Windows folder.
11/03/2021
Analyst Software
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What is the Maximum Sampling Speed of the Echo® MS System? There are two modes for the Echo® MS system, normal and fast. The normal mode maximum sampling speed is 1 sample/s. In fast mode, the maximum sampling speed is 3 samples/s.
05/05/2022
Pharma CRO
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Software
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How Can I Set the Integration Algorithm in the SCIEX OS Software? To set the integration algorithm prior to processing quantitation data, select the Project Default Settings option in the Projects menu in the SCIEX OS software under the Analytics tile.
10/14/2022
SCIEX OS
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Adjusting Settings on a New Installation of DiscoveryQuant Software to Trigger a Run A new installation of DiscoveryQuant (DQ) software was not triggering injections with an Acquity UPLC. Adjustments to the settings in DiscoveryQuant included changing the autosampler type, building a new hardware profile, re-establishing communications between the LC and MS, specifying a plate location, and disabling the Look Ahead injection type.
03/31/2017
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PA800 How To - Installing the LIF Aperture and Probe Stabilizer Installing the LIF Aperture and Probe Stabilizer
05/02/2017
Pharma CRO
|
PA 800 Plus Pharmaceutical Analysis System
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How To Generate a List of All Installed Programs and Windows Updates To generate a list of all programs installed on a PC and a list of Windows updates, select the Programs and Features icon in the control panel. A list of all installed Windows updates can be created from the View Installed Updates screen.
02/21/2020
Software
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Checking for Administrator Rights on a Windows 10 PC before Installing Analyst®/SCIEX OS software There are three simple steps to determine which Windows users are listed as administrators before installing SCIEX software.
04/16/2020
Software
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Is Watson LIMS Software 7.6.1 SP1 Compatible with Analyst® Software 1.7.2 on Windows 10? Yes, Watson LIMS software 7.6.1 SP1 is compatible with Analyst® software 1.7.2 on Windows 10. Please run as administer when installing both the Watson and the Analyst software to ensure LIMS integration between the two.
03/11/2022
Pharma CRO
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Software
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Can Report Templates from Analyst® or MultiQuant™ Software Be Used with SCIEX OS? Report templates used previously with Analyst® or MultiQuant™ software should work with SCIEX OS, with the exception of MultiQuant templates that include a table query.
07/03/2018
SCIEX OS
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Starting an Analyst Software Data File (.wiff) with a Space Can an Analyst® software data file name start with a space? The answer is yes. It is not a good practice to start the file name (.wiff) with a space, but Analyst software does allow the user to do that by using the format of "Subfolder name\ Datafile name" in the data column of the batch.
05/25/2018
Clinical
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Analyst Software
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Optimal CE Voltages for Peptide Analysis on TripleTOF® Systems The collision energy (CE) and the collision energy spread (CES) values needed for peptide analysis (during protein IDA identification and SWATH® acquisition) can be optimized using Information in the rolling CE setting embedded in the Analyst® TF software.
05/31/2018
Academia Omics
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Pharma CRO
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Analyst Software
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What Is the Latest Nano Acquity Driver that Is Supported by Windows 7 OS (32 and 64 bit)? The latest Nano Acquity driver that supports the Windows 7 operating system (both 32- and 64-bit) is the ACQUITY UPLC M-Class Driver Pack version 1.55.
10/31/2017
Analyst Software
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Custom Calculations or Flagging Rules Not Working after SCIEX OS Software Upgrade or Reinstall After a reinstall or upgrade of SCIEX OS software, the custom calculations and flagging rules of a processing method may not work properly. A config file for the software will need to be edited to restore functionality.
09/30/2022
SCIEX OS
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A SCIEX technical support agent may ask you to create and send a dump file to provide a snapshot of a SCIEX software application's processes, loaded modules and memory at a certain time point. This article explains how a dump file is created.
03/20/2020
Software
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Adding Users to the SCIEX OS Software Security Database To add users to SCIEX OS software Security Database, the user who installed the software needs to navigate to the User Management section in the Configuration mode and select the plus sign next to the User name or group drop-down menu.
09/23/2019
SCIEX OS
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Compatibility of ProteinPilot Software 4.5 Beta with Microsoft Office 2016 ProteinPilot software 4.5 beta is not compatible with Microsoft Office 2016.
10/16/2018
Academia Omics
|
ProteinPilot Software
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Why Use the Enterprise Edition of SimGlycan® Software? SimGlycan Software (a product of PREMIER Biosoft) predicts glycan and glycopeptide structures from SCIEX mass spectrometer-acquired MS/MS data. Some of the advantages of using the enterprise edition of SimGlycan software include being able to create glycan templates so that novel glycan structures can be added to the database.
11/11/2019
Academia Omics
|
SimGlycan Software
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Enabling and Disabling the Data File Checksum Feature in SCIEX OS Software To enable or disable the data file checksum feature in SCIEX OS software, navigate to the Configuration workspace in SCIEX OS software. Under the Projects tab under Data File Security, select the checkbox for Enable checksum writing for wiff data creation.
03/11/2022
Pharma CRO
|
Software
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Increasing the Maximum Injection Volume for an MPX™ Software System To change the default injection volume in MPX™ 1.2.1 software, the MaxInjectVolume line in the MPX configuration file (Multiplex.INI) can be edited. Additionally, the value added to the injection volume field in the Analyst software batch editor (on the Sample tab) will override the configured MPX injection value during an acquisition run.
10/03/2019
MPX Software
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How Is CEQ/GeXP Data Exported in the ABI Format? This document explains how to export data files acquired with the CEQ/GeXP software into an ABI format for data reprocessing purposes.
04/02/2019
GenomeLab GeXP Genetic Analysis System
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What is the Source of the Atomic Weight Information in BPV Flex Software? BPV Flex software uses the same source of atomic weight information as BioPharmaView™ software. The theoretical value required for the intact workflow uses the average molecular weight; the peptide workflow uses the monoisotopic weight.
11/02/2021
Academia Omics
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Pharma CRO
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BioPharmaView Software
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When setting up an information dependent acquisition (IDA) method, there is an option for including the retention time (RT) for analytes in an inclusion or exclusion list. In the inclusion/exclusion table, users can limit the masses in the list to a certain retention time with a specific width. However, sometimes the retention time is unknown, and its not clear what value to add for RT column.
03/03/2023
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Can the Probes and Electrodes for the OptiFlow® Ion Source Be Used with the OptiFlow Pro Ion Source? The probes and electrodes for the OptiFlow® Ion Source can be used with the OptiFlow Pro Ion Source.
11/06/2020
QTRAP Systems
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Triple Quad Systems
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Where Is Guided Optimization Found in the SCIEX OS Software? The SCIEX OS software offers various guided optimization methods in the MS Method mode.
02/18/2022
SCIEX OS
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Chromatograms Are Not Appearing in Reports Created with Reporter Template Suite When using MultiQuant™ or SCIEX OS software to create a report with Reporter Template Suite software, chromatograms are not appearing in the report. Instead, the report shows the text "This image is not available" where the image should appear. If the tag, Picture: Peak Review, is used, then the Label field must contain a value that matches the name of a column in the results table or it must be blank.
11/22/2021
Analyst Software
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When viewing an analyte's chromatogram in a report, the internal standard peak that is overlaid with the analyte's is not normalized in the report's chromatogram and part of the peak appears out-of-bounds in the peak review image. If you see an internal standard peak in the peak review pane of MultiQuant™ Software or SCIEX OS Software that is not normalized to the analyte's peak size, double click on the x-axis of that particular chromatogram.
12/04/2020
SCIEX OS
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MultiQuant Software
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How to Save Application and System event logs in Windows 7 The Windows event logs often contain crucial data about the performance of SCIEX software. Follow these steps to save your system and Application event logs so that they can be analysed by the SCIEX support team.
06/15/2017
Software
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Troubleshooting Amplifier Reset An Amplifier Reset alert simply means that the pump has emptied and refilled. As the pump has a finite volume then this refilling is expected if running for a long time or at a high flow rate. Note that an Amplifier Reset is an Alert not an Error. If an Amplifier Reset occurs the pump will refill and continue to pump at the programmed rate. An Amplifier Reset will not cause the sample batch or queue to stop. If an Alert message appears indicating that an Amplifier Reset has occurred the first step is to determine if this is a natural reset or not. In the following section are steps described how to determine the cause of an amplifier reset.
09/04/2016
Academia Omics
|
Does ProteinPilot™ Software 5.0.2 Support MALDI TOF/TOF™ Systems? Description of which ProteinPilot™ software versions still support 4800 and 5800 MALDI TOF/TOF™ systems.
07/14/2019
Academia Omics
|
Pharma CRO
|
ProteinPilot Software
|
What is my Source Exhaust and how does it work? Description of the Source Exhaust components and common requirements to maintain optimal performance
09/12/2017
Mass Spectrometers
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SimGlycan® software is a comprehensive glycan and glycopeptide drawing and structure analysis software.
11/11/2019
Academia Omics
|
Pharma CRO
|
SimGlycan Software
|
PA800 How To - Cartridge Removal Video demonstration of Cartridge Removal on the PA800 system
05/02/2017
Pharma CRO
|
PA 800 Plus Pharmaceutical Analysis System
|
Changing Parameter Settings Options in Analyst® Software Changing the options available for individual parameter settings in Analyst® software can be done by selecting Configure or Tune mode and then going to Tools > Settings > Parameter Settings.
02/28/2019
Analyst Software
|
Where Can LIF Emission and UV Bandpass Filters Be Ordered? UV bandpass filters used with the fixed wavelength UV detectors or emission filters for the laser induced fluorescence (LIF) detector can be ordered from common optics companies such as Andover Optics or Newport Optics.
12/26/2018
PA 800 Plus Pharmaceutical Analysis System
|
When Should I Use Retrieve Configuration in Analyst® Device Driver Configure Mode? In Analyst® Device Driver, when adding or changing a CTC PAL3 autosampler configuration, the Retrieve Configuration command must be performed in the Configure mode in the CTC PAL3 LC sampler dialog.
11/10/2020
Analyst Software
|
No, the Installation Repair Tool in SCIEX OS software can not be used to assess the installation of the Central Administrator Console (CAC) software.
03/03/2023
Pharma CRO
|
Software
|
Tuning 4500,5500 and 6500 using Instrument Optimization Walk through of instrument optimization
02/05/2016
Mass Spectrometers
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Can a LIMS System Be Connected Directly to SCIEX OS Software? Yes, SCIEX OS software supports the ability to send results directly to Watson LIMS. Other LIMS connections are possible through a third-party provider, Data Innovations.
11/02/2021
SCIEX OS
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Where Is the Download for the SCIEX All-In-One 2.0 with NIST 2017 Library? To download the SCIEX All-in-One HR-MS/MS library 2.0 and NIST 2017 MS/MS library (PN 5061635), go to the downloads page on the SCIEX website, and select the All-in-One library and the NIST library and download them both. Activate and install the licenses for each library.
07/09/2018
LibraryView Software
|
How to find Computer ID for Win XP Description of how to use the Command Prompt of Windows XP to find the Computer ID used when licensing Sciex software.
04/07/2017
Software
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How To Create a Metric Plot in Analyst® Software In Analyst® software, there are multiple ways to view a metric plot in order to see trends quickly after generating a results table.
12/02/2022
Analyst Software
|
Can Both Analyst® Software and SCIEX OS Software be Used for Acquisition on the Same PC? No, Analyst® and SCIEX OS software cannot be used for acquisition on the same computer. Analyst software will be removed from an acquisition PC if it is upgraded to use SCIEX OS software for acquiring data.
05/18/2022
Academia Omics
|
Clinical
|
Environmental Industrial
|
Food and Beverage
|
Forensics
|
Pharma CRO
|
Software
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Exporting Libraries from MasterView™ Software to a New Computer To use the set of libraries imported into MasterView™ software on another PC – or to switch between two sets of libraries – consider using the command line tools to export the library snapshot.
05/14/2019
MasterView Software
|
Changing the Comparison Sample Assignment in Analytics in SCIEX OS Software When reviewing a results table in the Analytics workspace of SCIEX OS software, users can change the comparison sample assignment from the one that was originally included in the processing method by selecting the option, Use the selected sample as the comparison sample.
04/01/2022
Academia Omics
|
Clinical
|
Environmental Industrial
|
Food and Beverage
|
Forensics
|
Pharma CRO
|
Software
|
How Do I Open a Port in Windows Firewall for the Central Administrator Console (CAC) Software? This article describes how to open the port for the Central Administrator Console (CAC) server when Windows Defender is used as the Windows firewall software.
09/30/2022
Pharma CRO
|
SCIEX OS
|
Adding a New Fragmentation Rule for EAD Data from a ZenoTOF 7600 System to the Mascot Server The steps for adding Mascot server fragmentation rules for an electron activated dissociation (EAD) cell on a ZenoTOF 7600 system are discussed in this article, as well as how to set up these rules in the Mascot Daemon client software version 2.6 or 2.8.
09/14/2022
Academia Omics
|
Mass Spectrometers
|
Overlaying Two or More Extracted Ion Chromatograms (XICs) in Analyst® Software Explore Mode To overlay extracted ion chromatograms (XICs) in Analyst® software Explore mode, click on the first XIC, then select Overlay in the Explore menu, and then select the second XIC. The second XIC will now appear in the same screen as the first XIC.
03/22/2018
Analyst Software
|
MultiQuant™ Software's sMRM Feature May Require an Extension License If an installation of MultiQuant™ software will not process sMRM data, an extension license may be need to be installed.
03/16/2018
MultiQuant Software
|
MPX Softare Error: MPX Driver Is Not in the Active Analyst® Hardware Profile To resolve the MPX software error "MPX driver is not in the active Analyst® hardware profile", remake the Analyst software hardware profile from scratch.
05/21/2018
MPX Software
|
System Error Causing SCIEX OS Software Acquisition Stoppage Resolved by Clearing Data Folder Sample acquisition using Sciex OS 1.5 software was stopped, resulting in a system error. The drive where the SCIEX OS Data folder was stored was full, so backing up and clearing out older data allowed for data acquisition to proceed.
05/13/2019
SCIEX OS
|
Creating a Hardware Profile in Simulation Mode in SCIEX OS Software To create a hardware profile in simulation mode in SCIEX OS software, select Simulate Device under the Settings tab when adding instruments to a hardware profile in the Configuration mode.
05/03/2022
SCIEX OS
|
Two Methods for Finding the Number of Points Collected across a Peak in Analyst® Software Determining the number of points across a peak in Analyst software can be done two ways: 1) View - Graph Information, and 2) Tools - Settings - Appearance Options - Other Graph Option - Yes (with scan number ) under Chromatogram.
01/11/2018
Analyst Software
|
Integrated Syringe Error Message Recieved while Using Manual Tune Mode in Analyst® Software While running Analyst® software in Manual Tune mode during compound optimization, an error message is received: "The current sample cannot be run because the syringe pump has stalled. The syringe plunger may be stalled in the syringe barrel." To resolve this issue, move the syringe holder back and clear error. If this doesn't work, replace the syringe, or if still needed, reset the MS.
12/21/2017
Mass Spectrometers
|
Purpose of the Gel and Water Rinses in the SCIEX Capillary IsoElectric Focusing Shutdown Method The purpose of the gel rinse followed by the water rinse in the SCIEX capillary isoelectric focusing (cIEF) shutdown method is to keep the capillary conditioned for use the next day.
12/05/2018
Capillary Electrophoresis
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Adding a Custom Column to a Results Table in SCIEX OS Software To add a custom column to a results table in SCIEX OS Software, select Add custom column from the More menu. Provide a name for the custom column and then select OK.
11/14/2021
SCIEX OS
|
For SCIEX Triple Quad™ and QTRAP® Systems, the Analyst® software creates backup instrument data parameter setting files when deactivating a hardware profile. Each time the hardware profile is activated, it loads the correct backup file according to the mode of the default instrument data and parameter setting files; because the file is changed, the date on the instrument data file also changes.
11/03/2021
Analyst Software
|
How do I measure Peak Signal to Noise in Analyst Software This article describes how to measure signal to noise using Explore or Quantitate mode with Analyst Software.
10/01/2015
Analyst Software
|
MultiQuant™ Software Feature Unavailable Error Message When installing a MultiQuant™ 2.0 software license, a MultiQuant Feature Unavailable error message is received. Installing the correct version of MultiQuant will resolve this issue.
05/21/2018
MultiQuant Software
|
Can the Lipidyzer™ Platform Be Upgraded to a Windows 10 Compatible Version? Lipidyzer™ platform 1.0.5 is only Windows 7 compatible, and there are no upgrades available that allow the software to be used on a Windows 10 system.
06/22/2022
Academia Omics
|
Pharma CRO
|
LipidView Software
|
Directly Transferring Data from MultiQuant Software to a LIMS System Data Innovation is a third party company that can set up a direct connection from MultiQuant to a LIMS system. http://www.datainnovations.com/support/driver-downloads
12/22/2017
MultiQuant Software
|
Locating the Computer ID(s) on a PC with a Windows Operating System The computer ID, also known as the physical or MAC address, is a number used when activating a software license on Sciex.com and contains a series of 12 characters followed by a space and then another 12 characters. This article explains a few different ways to generate the computer ID on a Windows 10 system. (These same steps apply to a Windows 7 system as well.)
05/06/2022
Software
|
Where Are Acquisition Method Files (Both LC and MS) Saved for SCIEX OS Software Projects? Each SCIEX OS software project has its own, separate MS and LC acquisition method files. This article describes where the method files are typically stored.
02/25/2022
SCIEX OS
|
How to Export UV Data into a Text File in SCIEX OS Software Open a data file that also contains UV data in SCIEX OS software in the Explorer module. Locate the Show menu and select UV/DAD/ADC Channel. Once UV trace is displayed, click Data and Peaks Table under the Show menu to display the table. Export the data by right clicking on the table and selecting Export Data as Text from the menu.
04/14/2020
SCIEX OS
|
What Are the New Visualization Features in the OneOmics Suite for DIA-NN Software Output Files? The DIA Results app, a new software feature in the cloud-based OneOmics suite for processing DIA-NN software output (TSV file), helps visualize proteomics data so that protein quantification results can be interpreted in the Analytics and Browser sections.
03/03/2023
Academia Omics
|
Software
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I am seeing inconsistent HPLC Peak shape. What may be the cause of this? Summary of potential causes of poor HPLC peak shape
12/04/2020
|
Renaming Analyst® Software Data Files Renaming an Analyst® software data file (.wiff and .wiff.scan) after forgetting to do so in the batch may prevent the data file from being reopened later.
10/18/2018
Analyst Software
|
Is Cliquid® 3.4 Software Compatible with MPX™ 2.0 Software? MPX™ Software is compatible with Cliquid® software and can be operated through the Cliquid software console; however, the Cliquid software Walk-up mode is not available.
04/16/2020
Cliquid Software
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MPX Software
|
Does SCIEX OS 1.4 Support Queries? SCIEX OS 1.4 does not support table queries in the Analytics component of the software.
07/02/2018
SCIEX OS
|
Creating an Ion Library for DIA-NN Software Using the Ion Library Generator in OneOmics™ Suite 3.3 This article describes how to create an ion library for DIA-NN in the OneOmics™ suite 3.3 using the Ion Library Generator.
02/10/2023
Academia Omics
|
Software
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Replacing the Sciex OS 1.0 License with a Sciex 1.2 Sciex OS 1.0 users must upgrade to Sciex OS 1.2. New license keys for Sciex OS 1.2 were distributed to Sciex 1.0 users. After removing the Sciex OS 1.0 license from C:/program files/Sciex/Sciex OS, the Sciex OS 1.2 license file should be installed from the desktop using the license activation screen in the Sciex OS 1.2 software.
03/06/2017
|
Transferring the Custom Column Settings from One MultiQuant™ Software Results Table to Another To transfer the custom column settings from one MultiQuant™ software results table to another, select Column Settings and then export the .cset file. Open the new results table and then import the .cset file.
07/02/2018
MultiQuant Software
|
Data Files Should Be Copied at the Project Folder Level in Analyst® Software The best way to copy Analyst® software data and method files is to copy and paste at the project level.
05/14/2018
MultiQuant Software
|
Saving Custom Columns As Default Columns in MultiQuant™ Software To routinely add the same custom columns to each newly generated MultiQuant results table, custom columns can be added to the table in the Batch Editor in Analyst® software that is created before acquiring a data set.
11/14/2019
Analyst Software
|
MultiQuant Software
|
How to Restore the Batch Rack Code in Analyst® Software when Using CTC Autosampler While creating a batch in Analyst® software with a CTC autosampler in the hardware profile, the drop-down menus appear blank for rack position, plate position, and plate code and do not contain the usual text selections. Reselecting the rack code value of 1 will restore the drop-down menu text.
05/03/2022
Analyst Software
|
How To Organize Data Using Sub-Folders in Analyst® Software When setting up a batch in Analyst® software, a sub-folder can be created in the project's data folder to organize data by date or acquisition time. To create the sub-folder, type a backslash next to the data file name in the Data File column.
11/04/2021
Analyst Software
|
Will Software Validation Ensure that Our Lab Is 21CFRpart11 Compliant? The SCIEX software validation service ensures that Analyst® software is configured correctly, that the necessary procedures are documented, and that objective evidence of these activities is provided to ensure 21CFRpart11 compliance.
02/04/2022
Software
|
How Can I Adjust the Dynamic CE Table in SCIEX OS Software? Sometimes the dynamic collision energy (CE) for peptides needs to be adjusted to get better fragmentation of the precursor ion. This article describes how to adjust the dynamic CE table.
10/20/2022
SCIEX OS
|
Chromatograms Are Randomly Missing from the Report after Upgrading Microsoft Office When a report is created using Sciex OS, MultiQuant™, or Analyst® software, one of the chromatograms is randomly missing. This issue is due to Microsoft Office 365 Apps for Enterprise or Business being installed, and this version of Office is not currently compatible with the current versions of SCIEX software.
11/04/2021
SCIEX OS
|
Analyst Software
|
MultiQuant Software
|
How to find Computer ID for Windows XP Description of how to use the Command Prompt of Windows XP to find the Computer ID used when licensing Sciex software.
09/04/2016
Software
|
Issue with Ion Ratio Calculations in MultiQuant™ Software 3.0.3 Resolved with HotFix 2 When removing a standard from the calibration curve of an analyte in MultiQuant™ Software 3.0.3, an error occurs where the ion ratio for analytes farther down the list gets improperly calculated and changed. This issue is resolved by installing HotFix 2.
08/08/2022
MultiQuant Software
|
Removing Server Path Names in the MultiQuant™ Software LIMS Transfer Dialog In order to enter the correct server address to enable LIMS transfers in MultiQuant™ software, delete the FilesFolderOptions.xml file in the folder C:\Users\User.Name\AppData\Roaming\AB SCIEX\MultiQuant3 and then restart the software.
04/14/2020
MultiQuant Software
|
Multiple Period Experiments Cannot Be Processed in BioPharmaView™ Software 2.x and 3.x Data processing for intact proteins and peptide mapping in BioPharmaView™ software versions higher than 2.x do not allow for multiple period experiments.
09/26/2019
Academia Omics
|
Pharma CRO
|
BioPharmaView Software
|
How Are Peptides Named in BPV Flex Software after in Silico Digestion? The general rule for naming peptides in BPV Flex software is: the first peptide resulting from a proteolytic cleavage is named T1 for sequences displayed from the N-terminus to the C-terminus; moving toward the C-terminus, the second proteolytic cleaved peptide is named T2, and so forth.
11/01/2021
Academia Omics
|
Pharma CRO
|
Software
|
What is the Analyst® Diagnostic Tool and How Can It Help Me? Analyst® Diagnostic Tool is an information-gathering program that is designed to provide insight on performance issues with Analyst software and the computer's operating system.
04/17/2020
Analyst Software
|
Power Down and Power Up the TripleTOF® System How to power down and up the TripleTOF systems
02/05/2016
Academia Omics
|
Environmental Industrial
|
Food and Beverage
|
Forensics
|
Pharma CRO
|
Can I Use My Own Calibrant Solution to Tune the QTRAP® or TripleQuad™ LC-MS/MS 7500 System? To tune and calibrate a SCIEX QTRAP® or TripleQuad™ LC-MS/MS 7500 system, a new calibrant, called the MS Tuning Solution, was recently introduced and must be used to tune the new instrument.
11/06/2020
|
Is SCIEX OS Software Compatible with Cliquid® Software? No, SCIEX OS software cannot coexist with the Cliquid® software on the same PC.
11/03/2021
Cliquid Software
|
Installing Analyst® 1.7 Software on a Processing PC with Win 10 Described below are two procedures for installing Analyst® 1.7 software on Windows 10: 1) for a PC with a SCIEX-issued version of Windows 10 and 2) for a PC not purchased from SCIEX.
10/16/2018
Analyst Software
|
Why is my Graph Selection Window in SCIEX OS transparent? Why is my Graph Selection Window in SCIEX OS transparent?
05/31/2017
|
How can I convert .wiff to NetCDF format Explanation of how to convert .wiff files to NetCDF using the Translat.exe program which is included with Analyst software
10/02/2015
Analyst Software
|
Can Multiple Users Log In to Windows while Analyst® MD Software Is Acquiring Data? If a user starts a batch using Analyst® MD Software and then signs out of their Windows account while Analyst Software is acquiring data, the software will close and suspend the run. It is not recommended to sign out of a user's Windows account if Analyst MD Software is acquiring data.
12/02/2020
Clinical
|
Analyst Software
|
Displaying Analytes Horizontally and Samples Vertically on a Report To create a report where the analytes appear horizontally (as column headers) and sample names appear vertically (at the start of a row) in a report, the For Each Analyte tag will need to be nested within the For Each Sample tag.
12/04/2020
SCIEX OS
|
Analyst Software
|
MultiQuant Software
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What Are the New Features in the ProteinPilot™ Software Found in the OneOmics™ Suite 3.3? This article describes the new software features recently implemented in ProteinPilot™ software 5.0.3 in the OneOmics™ suite version 3.3. The version of ProteinPilot software found in the OneOmics suite has nearly the same features as the desktop version of ProteinPilot software.
02/10/2023
Academia Omics
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Software
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General Guidance for Antivirus and Backup Software Used on Acquisition PCs The antivirus or backup software on Analyst® software acquisition workstations should be configured in a manner that will disable real-time scanning and archiving of files in the Analyst Data folder.
12/26/2019
Software
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Can Xcalibur Software 3.x and Eksigent Software 4.3 Operate on Windows 10? SCIEX's Eksigent software and Thermo Scientific's Xcalibur software have not officially been tested together on a Windows 10 operating system. The Eksignet software can be installed on a Windows 10 PC, but then it cannot be configured with any Xcalibur software versions. However, both software types can be configured together on a system running Windows 7, 64-bit.
03/20/2020
Academia Omics
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NanoLC 400
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Location of the Analyst® Software Configuration Files The configuration files contain the processing parameters for library searching in Analyst® software. These parameters can be changed under the ConfirmationLibrarySearch.config or MultipleCandidateLibrarySearch.config files, and these files are typically saved under C:\Program Files (x86)\AB SCIEX\AnalystReporter\Resources\AlgorithmConfigFiles.
11/03/2021
Analyst Software
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Resolving Hexadecimal Errors when Creating Reports in MultiQuant™ Software If the error "Incorrect Argument. Hexidecimal value 0x1F is an invalid character" is received when creating reports with MultiQuant™ software, trailing spaces from the sample name need to be removed.
05/24/2019
MultiQuant Software
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What is the Supported Control Software for the Echo® MS System? The Echo® MS System is controlled by SCIEX OS software, version 1.6.10. This is the only supported software for direct control of this instrumentation. SCIEX OS software supports an open application programming interface (API) for the creation of integrated control through third-party automation software packages.
10/19/2020
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Analyst® Device Driver 1.3 Tutorial The Analyst® Device Driver 1.3 Tutorial is a guide for the device driver usage and contains troubleshooting tips.
05/03/2018
Analyst Software
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Where Are Report Templates Located for MasterView™ Software? Report templates for MasterView™ software are located under the following root directory: C:\Users\Public\Documents\AB SCIEX\MasterView\Templates
10/08/2018
Software
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Searching for ProteinPilot software files using Windows Explorer cannot be done because there are two files acquired under the same file name. This is a long known issue for all ProteinPilot versions that only one file per file name can be searched using ProteinPilot software.
03/07/2018
Academia Omics
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Pharma CRO
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ProteinPilot Software
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MultiQuant™ Software Installation Error Due to Some Prerequisite Components Needing Reinstallation A successful MultiQuant™ software installation requires that the SCIEX Reporter software and a .pdf reader program, PDF Factory, be installed prior to the installation of MultiQuant.
10/18/2018
MultiQuant Software
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What Sample Matrices Are Supported on the Echo® MS System? The sample matrices that can be supported on the Echo® MS system must correspond to one of the supported liquid classes, either AQ or SP.
10/19/2020
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Unable To Change Sample Loop Volume With Analyst® Hardware Configuration For ExionLC™ AD System After replacing the sample loop for a different volume on an ExionLC™ AD system, the volume of the loop can be changed on the LC controller panel but not within Analyst® software hardware configuration.
09/14/2022
ExionLC AD
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Analyst Software
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The SCIEX OS software installation folder path is limited to 118 characters or less.
11/03/2021
SCIEX OS
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Can a WIFF or WIFF2 File from SCIEX OS Software Be Split into Subset Data Files? There is currently no script or software that allows for splitting a multi-sample data file from SCIEX OS software (i.e., .wiff or .wiff2) into individual subset files.
02/18/2022
SCIEX OS
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Please ensure that the path to the installation folder for SCIEX OS software is 118 characters or less. If it is longer, the installation of SCIEX OS software will not proceed.
03/03/2023
Software
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SCIEX Registered Software Webpage Lists All Recently Activated Licenses The SCIEX Registered Software webpage (https://sciex.com/support/registered-software) lists all recently activated licenses.
05/21/2018
Software
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Locating 66-Vial Plates in the Analyst® Software Plate Code Selection Analyst® Device Driver supports 66-vial plates, but they are not initially found in the plate code selection of the Analyst software batch editor. To view this plate option, the rack code needs to be changed to 2 Drawer Plates and then the user can find both of the 66-well plate code options: 66VialGen PlateR and 66VialGenPlateC.
11/07/2018
Analyst Software
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The Analyst® Device Driver 1.3 software includes a Multi-wash section on the Multisampler tab when the LC portion of an Analyst software method is open, but it is grayed out. If the multi-wash hardware accessory is not installed on the autosampler, the Multi-wash screen will not be available for editing.
11/04/2021
Analyst Software
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Where Is the License for a LibraryView™ Software Library Installed? If the LibraryView™ software library cannot be viewed through the software after installing it, the location of the library license needs to be checked. It should be installed to C:\Program Files\AB SCIEX\LibraryView\bin.
03/16/2018
LibraryView Software
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Maximum Setting for Collision Energy (CE) during Compound Optimization The maximum value that can be used for collision energy (CE) during compound optimization in Analyst® software is 130, even though the CE value can be set to 180 in the parameter settings.
12/22/2017
Analyst Software
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PA800 How To - Capillary Removal Capillary Removal
05/02/2017
Pharma CRO
|
PA 800 Plus Pharmaceutical Analysis System
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Unable to Configure a Shimadzu LC System after Upgrading to Analyst® 1.7 Software A Shimadzu LC system may not be recognized and may not be able to be configured after an upgrade to Analyst® 1.7 software if a computer image on the PC was not sourced from SCIEX.
10/04/2019
Analyst Software
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Can I Use the TOMKit Library with SCIEX OS and/or LibraryView™ Software? The TOMKit Libraries are newer library entities, and they are not compatible with SCIEX OS or LibraryView™ software. The TOMKit libraries are for use with Agilent instruments only currently.
12/15/2021
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Building a Quant Method in SCIEX OS Software for DAD Data Peaks from DAD or UV chromatograms that were acquired during an LC/MS experiment can be quantified in SCIEX OS software. Open a new quantitation method in SCIEX OS software, and then select the representative sample. On the Components tab, select the drop down menu in the Experiment Index column. Select the DAD experiment for each transition and add the desired wavelength to quantitate in the Start - Stop (Wavelength) column.
12/15/2021
SCIEX OS
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Which Version of Watson LIMS Is Compatible with SCIEX OS Software 1.7? SCIEX OS software 1.7 has been tested with Watson LIMS server/client version 7.6, Oracle server/client 12.2.0.1.0 SE (64-bit) and 12.2.0.1.0 (32-bit).
04/16/2020
SCIEX OS
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How Do I Import and Export ChemoView Settings ChemoView settings can be Exported so that they can be backed up or transferred between instruments or computers using the Import function.
12/22/2015
Clinical
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ChemoView Software
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Reporter Error: Template Not in Your Trusted Location If a reporter error shows that the template is not in the trusted location when trying to save or move a report template, then the Trusted Locations list in Word must be updated to include locations where SCIEX reports and templates are edited.
11/04/2021
SCIEX OS
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Analyst Software
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MultiQuant Software
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What Default URL Is Used for Configuring the Mascot Server with ProteinPilot™ Software? Configuring the Mascot server from the ProteinPilot™ software requires the default URL to be used.
11/16/2017
Academia Omics
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Pharma CRO
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ProteinPilot Software
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Where Are the SCIEX OS Software Project Audit Trail Archives Stored? The audit trail records for a SCIEX OS software project are stored in the Audit Data sub-folder for the project. The audit trail file name is ProjectAuditEvents.atds.
03/11/2022
Pharma CRO
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Software
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What Curtain Gas Setting Should Be Used on the QTRAP® 6500 System? The QTRAP® 6500 system has a limit of 50 psi for the curtain gas. Curtain gas settings should not be higher than 40-45 psi.
12/21/2017
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Is It Possible To Monitor More MRMs Per Well than Specified for the Echo MS System? Yes. The specified four MRMs per well is based on the peak width from a single droplet ejection.
10/19/2020
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License Error when Launching LipidView™ 1.2 Software on Windows 10 When launching LipidView™ 1.2 software on Windows 10, a license error appears indicating that the license has expired, even when a permanent license has been installed. To resolve this issue, right click on the LipidView software icon and select Run as Administrator to launch the software.
08/09/2019
LipidView Software
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Setting Up Manual Integration (Percentage Rule) in SCIEX OS Software To set up the parameter Manual Integration (Percentage Rule) in SCIEX OS software, a results table and peak review will need to be open in Analytics mode. In the peak review pane, select the Peak review display settings button under the Options menu. Then select the Appearance tab. The manual integration percent rule can be set by clicking the drop down arrow as shown below.
05/03/2022
Academia Omics
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Clinical
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Environmental Industrial
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Food and Beverage
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Forensics
|
Pharma CRO
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SCIEX OS
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Analyst® Software Error: Please Enter Positive Numeric Value Only While attempting to select manual tune mode, users of Analyst® software may see the error message "Please enter positive numeric value only." This error results from commas instead of periods being used as decimal points in non-English based operating systems.
09/01/2022
Software
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To Install MultiQuant™ Software, Log into Windows as an Administrator When installing a MultiQuant™ software license, an error message appears that says "The feature you are trying to access is unavailable. Cannot find license file/License File cannot be opened." To override this error, the software and license need to be installed while logged into Windows as an administrator.
05/31/2018
MultiQuant Software
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Can a Precursor-ion IDA Experiment Be Performed on a SCIEX TripleTOF System? None of the SCIEX TOF instruments, 5600, 5600+, 6600, X500R, or X500B, can do a precursor ion IDA experiment.
04/13/2017
Analyst Software
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QTOF Systems
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General SQL Installation Errors for SCIEX OS and LibraryView™ Software Installing any program with SQL-based software components (e.g., SCIEX OS and LibraryView™ software) requires that a certain rules are observed. These rules are set by Microsoft, and are not covered in the release notes for the SCIEX software installation that includes the additional of SQL components.
05/23/2019
SCIEX OS
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LibraryView Software
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My Annual SCIEX License Suddenly Stopped Working Before It Expired, Why? A new annual SCIEX subscription license stopped working suddenly despite having many months of use remaining.
12/15/2021
Software
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Using 32 Karat Software with a Corporate Network or Domain 32 Karat software can be used with a company network 1) to control user logins and permissions via a Windows operating system (OS) network domain controller and 2) to allow access to network printers and hard drives.
12/26/2018
PA 800 Plus Pharmaceutical Analysis System
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MultiQuant™ Software's Audit Trail and Security Feature Requires a Base and an Extension License When installing MultiQuant™ software with the audit trail and security extension license, the license installs successfully, but MultiQuant software does not launch. Instead, a -5 error code appears and the error message displayed reads, "This feature is not licensed. It cannot be used." MultiQuant requires a base license to be installed alongside its audit trail and security extension license.
12/11/2017
MultiQuant Software
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Users Are Unable to Save or Submit Batches with Long File Paths in Analyst® Software 1.7.2 In Analyst® software 1.7.2, users cannot save or submit an acquisition batch if the project path is longer than 126 characters.
11/02/2021
Analyst Software
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What Are the Advantages of the .wiff2 Data File Format? The .wiff2 meta data file generated by SCIEX OS software is designed to offer users improved security for their data. One of the primary advantages is the .wiff2 meta data file is encrypted, which prevents software users from tampering with results.
10/06/2021
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The Report Option Is Missing from the MultiQuant™ Software File Menu When the Report option is missing entirely from the MultiQuant™ software File menu, check that the version of Microsoft Office installed is correct.
05/04/2017
MultiQuant Software
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Explanation of 32 Karat License Key Program and User License Types 32 Karat software requires a hardware license key to launch, and on older versions, a similar software license key is installed from a floppy disk.
04/02/2019
PA 800 Plus Pharmaceutical Analysis System
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Setup Cannot Continue Error when Installing MultiQuant™ Software The MutliQuant™ software installation error "Setup cannot continue until all system components have been successfully installed" indicates that a Windows 10 operating system is present and the software must be reinstalled on a Windows 7 system.
06/29/2017
MultiQuant Software
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Creating a Processing Method in ChemoView™ Software To create a new processing method in ChemoView™ software, select the Add New Processing Method button.
09/25/2019
ChemoView Software
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DiscoveryQuant Quicktune DP 0 DP Scan Problem Using DiscoveryQuant 2.1.3 Quick Tune will set the DP value to 0 and then Fine Tune will fail as it has an invalid DP value. The temporary Q3 MI scan method for the quicktune will show the MH ion with 2 DP scans both at 200v though this voltage may vary.
10/01/2015
Pharma CRO
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DiscoveryQuant Software
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Is the Shimadzu LC-40 Fluorescence Detector RF-20AXS Supported in Analyst® Software? Yes, Analyst® software 1.7.2 can directly control the Shimadzu Nexera LC-40 fluorescence detector RF-20AXS.
11/03/2021
Analyst Software
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Can I display the pressure trace of a chromatogram when I use an Agilent LC system with Analyst Description how to activate the pressure trace in the hardware profile
06/02/2016
Analyst Software
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How Do I Select a Library and Perform a Library Search in SCIEX OS Software? To select a library to use with a targeted or non-targeted screening method in SCIEX OS software, open an existing processing method or edit an embedded method from a results table. Ensure that the checkbox for Quantitation and targeted identification or for Non-targeted screening is selected. Then navigate to the Library Search option to set the library search parameters.
12/05/2021
SCIEX OS
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Are Validation Services Available To Install and Test the SCIEX OS Software in My Lab? Yes, the SCIEX validation services team has helpful and cost-effective services for SCIEX OS software validation.
05/18/2022
Academia Omics
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Clinical
|
Environmental Industrial
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Food and Beverage
|
Forensics
|
Pharma CRO
|
Software
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What Are the Specifications for Installing SCIEX OS Software 2.2 on an Acquisition PC? To install SCIEX OS software version 2.2 on an acquisition workstation, the PC needs to meet specific requirements. The following PCs are supported: 1) SCIEX workstation or workstation+ and 2) SCIEX Alpha workstation 2020.
04/01/2022
Academia Omics
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Clinical
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Environmental Industrial
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Food and Beverage
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Forensics
|
Pharma CRO
|
Mass Spectrometers
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Software
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How Is a Formula Column Added to a Result Table in Analyst® Software? To add a formula column to a results table in Analyst® software, right click on the results table and select Add Formula Column.
12/17/2019
Analyst Software
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Which Version of DiscoveryQuant™ Software Supports the Acquity LC on Windows 10? The Windows 10 compatible version of DiscoveryQuant™ software that supports Acquity LC is version 3.0.1 Hotfix 2.
11/03/2021
DiscoveryQuant Software
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Can SCIEX OS Software Be Installed on a PC with Windows 10 Hotfix2? No, SCIEX OS software cannot be installed on a PC with Windows 10 hotfix2.
11/03/2021
Software
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How Are Retention Times Updated in MultiQuant™ Software Processing Methods? There are two ways to update retention times (RTs) in MultiQuant™ software quantitation methods. One way is temporary and the other way is permanent.
12/11/2017
MultiQuant Software
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Are CloudConnect and SWATH® MicroApps within PeakView® Software Windows 10 Compatible? The software package, PeakView® 2.2, CloudConnect 1.2 beta and SWATH® 2.0.1 software. is needed to perform the OneOmics workflow and/or SWATH protein data processing and is Windows 7 and Windows 10, 64-bit compatible.
07/14/2019
Academia Omics
|
PeakView Software
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ProteinPilot Software
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SWATH Acquisition
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How to Add Select Samples to a Report Created in SCIEX OS Software To add only selected samples from a results table created in SCIEX OS software in a report, uncheck the Reportable column for the sample you do not want to report. Then edit your report template to include an If statement within a ForEachSample loop to include $Reportable="TRUE".
03/20/2020
SCIEX OS
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Valve Model Will Not Stop Equilibrating In SCIEX OS Software 2.1 When equilibrating any MS method on a SCIEX 7500 system, the "Valve Model" will never finish equilibrating even after the specified time when using SCIEX OS software 2.1.
09/14/2022
SCIEX OS
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Triple Quad Systems
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MultiQuant™ or SCIEX OS Software: The Ion Ratios on the Report and Results Table Do Not Match When a query file is used to calculate the ion ratio calculations in a MultiQuant™ or SCIEX OS software report, the values for the internal standards ion ratios in the report output will not match those in the results table. This issue is observed when the internal standards are not assigned to the analytes in the order in which they are listed on the quantitation/processing method.
11/04/2021
SCIEX OS
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Analyst Software
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MultiQuant Software
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How Many Modified Amino Acids and Modifications Can Be Added in PeakView® Software? In general, the number of modified amino acids and modifications that can be added is unlimited in the PeakView® software.
02/28/2019
PeakView Software
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Is It Possible to View Extracted Ions in Separate Panes in SCIEX OS Software? To show extracted ions in SCIEX OS software, the data file must be opened in the Explore module and then Ctrl+E is used to extract the ions of interest. The Split Traces into Separate Panes option in the Graph menu allows for the extracted ions to be displayed in separate panes.
12/15/2021
SCIEX OS
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Should I Revalidate My Software? Periodic reviews of validated systems must be performed to ensure that no changes have been made that affect the validated state of the system. If there is a change, then the software needs to be revalidated.
02/11/2022
Software
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Integrating Peaks from a DAD or UV Chromatogram in Analyst® Software Analyst® software Quantitate mode can be used to integrate peaks from DAD or UV chromatograms that were acquired during an LC/MS experiment.
05/11/2018
Analyst Software
|
How Can I Get a Biologics Explorer Trial License? To obtain a Biologics Explorer (BE) 1.x trial license, send an email to biologics.explorer.orders@sciex.com with a request for a 30-day trial.
09/14/2022
Academia Omics
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Pharma CRO
|
Software
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Modifying a Report Template to Report Select Sample Types Using IF Statements An IF statement can be added to limit the sample types that need to be output to a report from a results table created in Analyst® software, MultiQuant™ software or SCIEX OS software. Below are few examples of how to write an IF statement within the loops ForEachSample or ForEachAnalyte.
11/08/2019
SCIEX OS
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Analyst Software
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MultiQuant Software
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Venting and Pumping Down the 5500 Series Mass Spectrometer How to remove the vacuum and pump the machine back down afterwards
02/05/2016
Mass Spectrometers
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Mapped Network Drive Issue when Using SCIEX OS Software Version 2.1.6 Many customers reported issues when using a mapped network drive to store for data for SCIEX OS software version 2.1.6; however, if the data was download to a local drive, no errors were received.
12/07/2021
SCIEX OS
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Uninstalling and Reinstalling SCIEX OS 1.x Software This article describes how to uninstall SCIEX OS software and manually remove certain files in order to completely remove the software.
03/21/2019
SCIEX OS
|
Switching from a hardware profile that contains an ExionLC (or Shimadzu LC) system to a hardware profile with an Eksigent LC when both LCs are connected to the PC can cause Analyst® 1.6.3 software to crash, resulting in communications issues.
12/02/2022
ExionLC 100
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ExionLC AC
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ExionLC AD
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Analyst Software
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PA800 How To - Capillary Storage Capillary Storage Details for PA800 System
05/02/2017
Pharma CRO
|
PA 800 Plus Pharmaceutical Analysis System
|
Intact protein script for TripleTOF™ instruments This knowledge article summarizes when to use the intact protein script in
05/03/2017
Academia Omics
|
Pharma CRO
|
Analyst Software
|
Shimadzu Autosampler Rack Must Be Seated Correctly for Analyst® Software to Acquire Samples Acquisition and equilibration errors in Analyst® software signalling a Shimadzu LC controller error may be the result of the autosampler rack not seated correctly in the autosampler housing.
12/21/2017
Analyst Software
|
MultiQuant™ MD 3.0.2 Software Will Not Open and No Error Message Appears If MultiQuant™ MD 3.0.2 software will not open when the desktop icon is selected and there is no error message appearing, this usually indicates that the software was installed on a non-compatible operating system. MultiQuant MD 3.0.2 software must be installed on Window 7, and it will not launch in a Windows 10 enviroment.
09/30/2022
MultiQuant Software
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Is the Database for DiscoveryQuant™ Software Limited to 1 GB? Yes, the size of the Microsoft Access database file is limited to 2 GB. However, the reliability of the database degrades before reaching the 2 GB limit, so it is suggested that DiscoveryQuant™ software users create a new database before the database exceeds 1 GB.
04/01/2022
Pharma CRO
|
Software
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What Is Skyline Software and What Data Types Does It Work With? This article includes a general description of the features of Skyline software and the possible data formats from SCIEX instruments that work with Skyline.
11/10/2017
Academia Omics
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Pharma CRO
|
Skyline Software
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PPG Reference Peak List Table Is Missing when Tuning and Cannot Be Opened To view the mass calibration peak lists in Analyst® software while using the manual tuning mode, go to the Tools menu and select Settings-Appearance options-Miscellaneous-Show Mass calibration peak list.
11/22/2017
Analyst Software
|
Removing Analytes from a MultiQuant Software Method (.qmethod) To remove an unneeded analyte's MRM transitions from a MultiQuant software method, the quantitation method must be opened and the Delete Selected Rows function must be used.
08/15/2018
Clinical
|
Environmental Industrial
|
Food and Beverage
|
Forensics
|
MultiQuant Software
|
Analyst Projects dropdown is not in alphanumeric order Analyst Projects drop down provides project list in what appears to be an unordered list
09/04/2016
Analyst Software
|
How to Electronically Reset a SCIEX 7500 System This article describes the steps for resetting the SCIEX 7500 series instruments.
09/14/2022
Academia Omics
|
Environmental Industrial
|
Food and Beverage
|
Forensics
|
Pharma CRO
|
QTRAP Systems
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Ekspert 400 AS3 Error Message Pump volume is not sufficient to run LC method without a restroke. Ekspert 400 AS3 Error Message Pump volume is not sufficient to run LC method without a restroke
09/04/2016
Academia Omics
|
Exporting a Centroid Spectrum from SCIEX OS Software To export a centroid spectrum from SCIEX OS software, load a data file and open a spectrum in explore mode; click Centroid Spectrum from Process drop-down list, and then select Export from the File drop-down list.
03/01/2019
SCIEX OS
|
Ekspert™ 400 LC system – Change the mobile phase How to change mobile phase on Ekspert™ 400 LC system
10/07/2016
Academia Omics
|
Pharma CRO
|
NanoLC 400
|
CDS Autocalibration without a HPLC System in the Analyst® Hardware Profile Analyst® software will acquire data even if the CDS autocalibration system is activated without a HPLC system in the hardware profile.
11/02/2018
Analyst Software
|
How Can Audit Trail Records Be Viewed from SCIEX OS Software? To view audit trail records in Sciex OS Software, open the Audit Trail workspace. The Audit Trial screen will appear. Select Workstation in the left pane to view the audit trail for the workstation. Select Project in the left pane to view the audit trail for the project of interest.
11/06/2020
SCIEX OS
|
Late elution of peaks on Eksigent nano Tempo Classic Late elution of peaks on Eksigent nano Tempo Classic
10/07/2016
Academia Omics
|
NanoLC 400
|
Computer error: Raid status was degraded This is a known issue in the ProteinPilot™ software 5.0.2 and was resolved with a patch.
03/09/2017
|
How to remove unused template definitions from DiscoveryQuant 2.1.x This document explains how to remove unused template definitions from the DiscoveryQuant Analyze setup window
09/04/2016
Pharma CRO
|
DiscoveryQuant Software
|
Why is the Option to Sum Multiple Ions Grayed Out in SCIEX OS Software? In order to use the Sum Multiple Ions option in the SCIEX OS software, the group name for each compound needs to be entered into the Group column.
02/28/2019
SCIEX OS
|
Access to Path Is Denied Error when Installing License When installing a Sciex software license, an error message appears that says the license was not sucessfully installed and the access to the path C:\Program Files\AB Sciex\.... is denied. This error message indicates that 1) the user doesn't have sufficient privileges to access the Program Files, or 2) the license file needs to be placed in correct location in the Program FIles manually.
05/14/2018
Software
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Improving Peak Resolution when Using Capillary Electrophoresis Basic tips are presented here for improving the overall resolution of capillary electrophoresis (CE) separations.
11/30/2018
PA 800 Plus Pharmaceutical Analysis System
|
Why Do the Calculated Concentration Values Show as Degenerate in SCIEX OS Software? In SCIEX OS software, if a value in the Calculated Concentration column displays as degenerate, this is because the values for Actual Concentration for standard samples have not been added to the results table.
12/16/2019
SCIEX OS
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MultiQuant Software
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Is Digital PicoView® Source Windows 10 compatible? Digital PicoView® Source is a nano ion source from New Objectives that is Windows 10 compatible and can be used with many SCIEX mass spectrometers.
04/16/2020
Academia Omics
|
Pharma CRO
|
QTRAP Systems
|
Triple Quad Systems
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QTOF Systems
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Can the Default Location of MultiQuant™ Software Queries Be Changed? It is not possible to change the default location of MultiQuant™ software queries.
10/09/2019
MultiQuant Software
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Where Are the Queries Used with MultiQuant™ Software Stored? MultiQuant™ software queries are saved in the following folder: C:\ProgramData\AB SCIEX\MultiQuant\Queries.
08/15/2018
Software
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Data Not Visible for New Results Table Processing in SCIEX OS Software To create a new results table in SCIEX OS software, users must browse to data sets (.wiff files) from the Analytics mode through the Results menu. When New and then Browse are selected to start a new results table, no data set is seen when the data folder is selected in the Select Folder menu. It appears as if the raw .wiff files are missing.
09/30/2022
SCIEX OS
|
What Are the Most Common Installation Issues for SCIEX OS Software 1.7? Some of the most commonly observed installation issues with SCIEX OS software 1.7 are summarized here. Instructions on how to uninstall previous versions of SCIEX OS software are also included.
04/28/2020
SCIEX OS
|
Importing a Library Package into LibraryView™ Software 1.3 To install a newly downloaded library package (.lpb file), select the import button in LibraryView™ software and then the correct file type.
10/22/2018
LibraryView Software
|
If the license expires for the Central Administrator Console (CAC) software, the server data is maintained in the CAC database, but users won’t be able to launch the CAC application. The SCIEX OS software installed on the client workstations will continue to launch and work with last retrieved data while the CAC server is not reachable.
09/16/2022
Pharma CRO
|
SCIEX OS
|
How to Remove "No Data" from Report Output Generated from SCIEX OS Software An IF/ELSE statement can be created to filter out the “No data” response in a report in SCIEX OS software.
04/04/2022
SCIEX OS
|
Detuning an Acquisition Method in Analyst® Software If the signal seems to be saturating during acquisition on a Triple Quad™ 5500 system using Analyst® software, one option is to detune the acquisition method by using non-optimized collision energy values for the MRM transitions.
12/21/2017
Triple Quad 5500
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Triple Quad 6500
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Analyst Software
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User Role Not Assigned Correctly in SCIEX OS Software To resolve the error "You do not have the correct SCIEX OS role permissions to access this product" in SCIEX OS software, the software needs to be opened under the Windows user login that the software was installed under.
04/05/2019
SCIEX OS
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How Do I Generate a Report with Only the Quantifiers in SCIEX OS Software? Open the Analytics workspace in SCIEX OS software and open a results table. In the More menu, click Table Display Settings. A list of column names will appear. Select Reportable to make this option visible. Selecting the Reportable column shows whether or not the result is included in reports, exports, and LIMS transfers. Under Reportable column, select Quantifiers for the component.
09/23/2019
SCIEX OS
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What Files Must Be Backed Up before an Analyst Software Reinstall? Back up the API Instrument project folder in the Analyst Data folder prior to any reinstall or upgrade of the Analyst software. To upgrade an older version of Analyst, remove and back up the Analyst Data folder and any remaining short cuts on your workstation. Reboot the PC and install the new version of the software.
12/11/2017
Mass Spectrometers
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Analyst Software
|
How Is a Hardware Profile Created in Simulation Mode with an Eksigent 4.x and Analyst TF Software? Description of the steps to place the Eksigent software in the AAO system of the Analyst® software and how to run it in simulation mode.
10/20/2017
Academia Omics
|
Pharma CRO
|
Micro HPLC Columns
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NanoLC
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Analyst Software
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SCIEX OS 1.5 Software Launch Errors Overcome by Starting Clearcore2 Services The Clearcore2 Service runs in the background for SCIEX OS 1.5 software. The service will need to be started manually in the Services section of the Control Panel if SCIEX OS will not launch.
02/28/2019
SCIEX OS
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Setting the High Limit Value in the MPX 2.0 Software for Real Time Data-Dependent Decision (RTD3) In the MPX software 2.0, the carryover detection feature requires that the values for the high or region height columns need to be defined for each component. These values are used to set the flag for the above upper concentration limit.
09/24/2019
MPX Software
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Can Standard Concentration Values Be Stored in a MultiQuant™ Software Quantitation Method? No, the concentration values for a standard or quality control samples cannot be stored in or saved to the MultiQuant™ software quantitation method.
10/09/2019
MultiQuant Software
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IF Statement Syntax for Calculated Columns in SCIEX OS Software 2.1.6 Reports created with SCIEX OS software use templates with embedded tags. One of the commonly used tags is the IF statement, and the basic syntax for this tag is as follows: if(<condition>;<value if true>;<value if false>)
11/04/2021
SCIEX OS
|
When Markerview 1.2.1 is used in conjunction with Microsoft Office 2013 report generation fails with the message This method or property is not available because this command is not available for reading.
10/01/2015
Academia Omics
|
MarkerView Software
|
Viewing Real-Time PDA or UV-Vis Data in Analyst® Software when Employing a Shimadzu AAO Viewing real-time photo-diode array (PDA) or UV-vis data is not possible in Analyst® software when employing a Shimadzu diode array or UV-vis detector.
12/22/2017
Analyst Software
|
Defining Analyte and Analyte Type in ChemoView™ Software To define a new analyte in ChemoView™ software, navigate to the Manage/Analyte module, and select the Add New Analyte button.To define analyte type, select the Setup menu and chose the Analyte Types option.
09/25/2019
ChemoView Software
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Yes, the SCIEX OS software Central Administrator Console (CAC) software can reside on the same server as the FlexNet Licensing Server.
09/20/2022
Pharma CRO
|
SCIEX OS
|
SCIEX Website Login Requires that Your Email Address Is Verified After creating your login for the SCIEX website, you will be asked to verify your email. Click on the link in the webpage that appears after your account is created or in the email sent to you by SciexNOW to activate your online account with SCIEX.
12/14/2017
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Can Analyst® Software Directly Control the Shimadzu SPD-M40 Detector? Analyst® software 1.7.2 can directly control the Shimadzu SPD-M40 detector through the Shimadzu MIMIC 2 driver that has been incorporated into Analyst software.
11/03/2021
Analyst Software
|
Submitting and Starting Sample Batch in Analyst® Software How to start acquiring data using Analyst software
02/05/2016
Mass Spectrometers
|
Analyst Software
|
Does My Acquisition PC Have a Bad Ethernet Card? This article summarizes some issues that might contribute to a bad network card.
11/13/2019
Software
|
Centering a Peak in a SCIEX OS Software Peak Review Pane To adjust the location of the peak in the window and to center it, select the peak review icon in the results table, click Options and then Peak review display settings. In the Zooming tab, select the Zoom time axis to view peak check box and add the desired retention time.
10/11/2019
SCIEX OS
|
How Are SWATH™ Acquisition Files Recalibrated? The procedure for recalibrating a SWATH™ acquisition file is outlined here.
08/24/2017
Academia Omics
|
Analyst Software
|
SWATH Acquisition
|
This article describes what to do to identify this POET error in more detail. A POET error can arise when saving a results table in Analyst® software, with the error typically arising when saving the results table file to a network drive.
11/02/2021
Analyst Software
|
Considerations for Bin Sizes when Creating a TOF Acquisition Method in Analyst® TF Software What does "bin size" mean and what is the rule of thumb for setting bin sizes when setting up acquisition methods for a TOF MS system in Analyst® TF software.
06/07/2017
ProteinPilot Software
|
Fatal Error in MultiQuant™ Software: The File or Directory Is Corrupted and Unreadable While opening a file or creating a results table in MultiQuant™ software, users may receive the error message "The file directory is corrupted and unreadable." Running the Windows file explorer drive check can resolve this issue.
09/16/2022
Software
|
How Can I Find the Computer ID on a Win 7 Operating System? To locate the computer IDs (MAC or physical addresses) on a computer with a Windows 7 operating system, run the DOS command ipconfig/all, and a list of physical addresses be provided.
11/01/2018
Software
|
How Do I Obtain a Trial License for SCIEX Software? To download and obtain a licensed trial for a SCIEX companion software, navigate to https://sciex.com/products/software#tryfree and select the software that you would like to try.
09/27/2017
Software
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How can I create a record of the security settings from Analyst Software Explains how to record your security settings from an Analyst workstation in either printed format or PDF file using a PDF printer.
12/22/2015
Analyst Software
|
How Is Peak Asymmetry Caluclated in Analyst® Software Quantitate Mode? Peak asymmetry is calculated in Analyst® software Quantitate mode using the formula ((Peak end time) - (Retention Time)) / ((Retention Time - (Peak start time)).
05/21/2018
Analyst Software
|
Resolving the Report Error in SCIEX OS Software: "Error during Report generation" This is a known issue in the ProteinPilot™ software 5.0.2 and was resolved with a patch.
10/22/2019
SCIEX OS
|
Changing the Integration Algorithm in SCIEX OS 1.6.1 Software To change the integration parameter used in a quantitative processing method in the Analytics module of SCIEX OS Software, select the Projects menu, and under the Projects default settings, select Quantitative Processing > Integration Defaults > Integration Algorithm.
10/17/2019
SCIEX OS
|
PA800 How To - Installing the Cartridge Aperture Procedure for Installing the Cartridge Aperture on the PA800 system
05/02/2017
Pharma CRO
|
PA 800 Plus Pharmaceutical Analysis System
|
How to Improve SCIEX OS Software Performance during Data Analysis SCIEX OS software may perform slowly during data analysis due to the location of the data files being processed. Relocating data files from a temporary location (such as the Windows desktop) to a SCIEX OS or Analyst software project folder that is located in the root directory mapped in the Configuration module of SCIEX OS software may improve the software performance.
10/30/2020
Software
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This is a known issue in the ProteinPilot™ software 5.0.2 and was resolved with a patch.
04/16/2020
|
How to Create an Ion Ratio Flag in a Report Template To flag an ion ratio as pass or fail in a report, an If/Else statement needs to be added using the MQ_Ion_Ratio tag.
05/03/2022
SCIEX OS
|
Analyst Software
|
How to Change the Font in a Report Template? Use these instructions to change the font of the text appearing in a report.
10/22/2020
Software
|
LightSight® Software Acquisition Mode Is Not Supported on a SCIEX 6500+ LC-MS/MS System LightSight® software version 2.3.x acquisition mode is not supported on a SCIEX QTRAP® or Triple Quad™ 6500+ LC-MS/MS System.
11/09/2019
Triple Quad 6500
|
LightSight Software
|
Specifications for the SCIEX Pre-Assembled Capillary Cartridge for CE-SDS Applications Specifications for the SCIEX pre-assembled capillary cartridge (part number A55625) are provided here.
05/03/2019
Capillary Electrophoresis
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Can I Use the SWATH® Variable Window Calculator 1.2 with All SCIEX QTOF Systems? The SWATH® Variable Window Calculator 1.2 is a new updated calculator that supports all SCIEX QTOF instruments with Analyst® TF and SCIEX OS software versions.
05/27/2022
Academia Omics
|
Pharma CRO
|
SCIEX OS
|
Analyst Software
|
SWATH Acquisition
|
Upgrading MultiQuant™ Software from version 3.0.1 to 3.0.x To upgrade to MultiQuant™ software from version 3.0 to version 3.0.1, 3.0.2 or 3.0.3, the following instructions should be followed.
03/22/2018
MultiQuant Software
|
Setting the Security Configuration to Single User Mode in Analyst® Software To set the security configuration to single-user mode in Analyst® software, navigate to the Configure mode, and then select the Security Configuration option. Select More from the bottom left side of the splash screen, and then select the Security tab at the top of the screen. Under the Security Mode tab, choose the Single User Mode option. Click Apply and OK.
05/03/2022
Analyst Software
|
This document summarises the equations used by Analyst to calculate the regression curves used for Quantitation.
12/04/2017
Analyst Software
|
An error results when selecting the ACQ-BSM tab when creating an LC method using the Acquity Method Editor accessed through Analyst® software. It can be resolved by selecting any other tab in the method editor screen.
03/16/2018
Software
|
Licensing Information for the SWATH Acquisition™ MicroApp in PeakView® Software When viewing license information in the PeakView® software Help menu, the SWATH™ acquisition microapp licensing info shows in the plug-ins list, but not in the PeakView License Report screen.
08/15/2018
PeakView Software
|
SWATH Acquisition
|
How Are the Method Parameters Chosen for Autocalibration Samples in the X500 Series? Method parameters for autocalibrations submitted in SCIEX OS batches are automatically chosen from the sample after the autocalibration.
04/10/2017
Academia Omics
|
Clinical
|
Environmental Industrial
|
Food and Beverage
|
Forensics
|
Pharma CRO
|
The Analyst application cannot be started because the current user is not in the security database. When Analyst is started the message The Analyst application cannot be started because the current user is not in the security database or has not been assigned a user type. You may also get this message if the network is not available. Please contact your administrator.
10/01/2015
Analyst Software
|
How Do I Migrate Data from a DiscoveryQuant™ 2.1 SQL Server to a DiscoveryQuant™ 3.0 SQL Server This article describes how to migrate DiscoveryQuant 2.1.x SQL Server Data to a DiscoveryQuant 3.0 SQL Server Installation
12/22/2015
Pharma CRO
|
DiscoveryQuant Software
|
Using the Purity Score To Assess a Match to My Library Search Results in SCIEX OS Software All peaks from both the unknown and library spectra are used to calculate the Purity Score, which is used to assess how well a compound matches an existing library compound. A high value indicates a high probability that the unknown spectrum has been correctly identified; a low value indicates the match is less certain.
04/23/2019
SCIEX OS
|
Locating the Name of a Server or PC Using the Command Prompt Window This article describes the DOS commands used to access the name of the server or PC.
05/14/2020
Academia Omics
|
Software
|
How Is a ChemSpider Software License Activated within PeakView® Software? The software activation procedure is described step-by-step for ChemSpider, which needs to be activated within PeakView® software's FormularFinder feature.
07/10/2017
Pharma CRO
|
PeakView Software
|
Nomencature Used by BiopharmaView™ Software for N-Gylcan Names BioPharmaView™ software uses predefined N-glycan structures (following the Ludger product names), or software users have the option to build their own custom modifications.
11/15/2018
Academia Omics
|
Pharma CRO
|
BioPharmaView Software
|
Can I Use a Regular Expression (Regex) to Filter Data in SCIEX OS Software? A regular expression (regex) can be used to filter data in a results tables and in reports created with SCIEX OS software.
10/22/2020
SCIEX OS
|
Enabling Hidden Folders in Windows 10 to Install an Analyst® Software License Many users find that they cannot activate their Analyst® 1.7 software license file on a Windows 10 operating system because the folder where the license file is installed does not show.
10/12/2018
Analyst Software
|
How Is the Software Protection Service in Windows 7 Disabled? The steps for disabling the Software Protection service in Windows 7 are provided here.
10/31/2017
Software
|
License Not Supported Error Appears after Installing MultiQuant™ Software After a new MultiQuant™ software installation, the error message, "License not supported" is displayed.
12/11/2017
MultiQuant Software
|
Internal Standard Recovery Calculations in MultiQuant™ and SCIEX OS Software SCIEX OS and MultiQuant™ software both calculate internal standard (IS) recovery but use different approaches. SCIEX OS software uses a built-in functionality for creating custom formulas to calculate IS recovery. MultiQuant™ software requires a query to be applied to the results table to perform the IS recovery calculation and to add a custom IS recovery column to the results table.
09/16/2022
SCIEX OS
|
MultiQuant Software
|
MPX™ Software Batch Stoppage due to Daylight Savings Time Shift If the computer clock updates for daylight savings time while MPX™ software is submitting a batch, data corruption and batch stoppage can occur. The clock must be set up so that automatic updates to the time do not occur.
03/12/2018
MPX Software
|
Does SCIEX OS Software Offer Tools To Assist with Achieving 21 CFR Part 11 Compliance? The features within SCIEX OS software that help users achieve 21 CFR Part 11 compliance are explored in the article, "SCIEX OS LC/MS Software and 21 CFR Part 11 Regulations".
11/06/2020
|
Upgrading a SCIEX Triple Quad System for Acquisition with SCIEX OS Software Upgrading a SCIEX Triple Quad system to use SCIEX OS software as the acquisition software (replacing Analyst® software) is a paid software upgrade and requires an engineer install the software and upgrade the firmware. To get more information about available options, please contact your sales associate.
05/18/2022
Academia Omics
|
Clinical
|
Environmental Industrial
|
Food and Beverage
|
Forensics
|
Pharma CRO
|
Software
|
Can a Processing Method Built in ChemoView™ Software Be Converted for Use in SCIEX OS Software? No, a processing method built in ChemoView™ software cannot be converted for use in SCIEX OS software. Files built in ChemoView software are not supported in SCIEX OS software. |
Does SimGlycan® Software Use .wiff2 File Formats from X500 Series Instruments? This article describes the possible file input formats for SimGlycan® software.
11/11/2019
Academia Omics
|
Pharma CRO
|
SimGlycan Software
|
Converting .Xml Templates to .Docx Reporter Templates for Analyst® 1.5 to 1.6 Software To convert the .xml files to .docx reporter templates for Analyst® software, the templates must first be updated to .docx. This is done by using the AB SCIEX Reporter Template Converter located in the following directory: C:\Program Files\ABSCIEX\Reporter Template Converter\Template Converter.
05/15/2018
Analyst Software
|
Acetic Acid Is Needed To Prepare the PepCalMix Peptides in the SWATH® Acquisition Performance Kit This article describes the experimental issues when formic acid is used to prepare the PepCalMix for the SWATH® Acquisition Performance Kit instead of 5% acetic acid.
11/09/2017
Academia Omics
|
Pharma CRO
|
Standards and Reagents
|
Obtaining a Smaller Volume Divert Valve for a 4500, 5500 and 6500 LCMS Systems To obtain a smaller volume divert valve for a 4500, 5500 or 6500 LCMS system, a new part must be ordered from Valco, part number of C52-2006I.
05/13/2020
Mass Spectrometers
|
Is There a "Batch-Convert" Function Available in Keystone™ Converter Software? Yes, Keystone™ converter software offers a command line option to allow for the creation of automated processes for converting large pools of legacy data.
11/02/2021
Software
|
What Are the Options in Data Explorer Software To Improve Spectral Quality? This document lists a couple of options on how to improve spectral quality using Data Explorer software 4.11
07/09/2018
Academia Omics
|
Activating a SCIEX Software Trial on Workstations that do not have Internet Connection Activating SCIEX software on a computer without internet access can be made simpler by following these steps
06/21/2018
Software
|
Replacing the Logo Shown in My Report in SCIEX OS Software To replace the logo shown in a report in SCIEX OS software after the results table is reviewed, click Reporting, then Create Report, and then save the Results Table. Click Replace Logo.
04/19/2019
SCIEX OS
|
The ACMP Peltier effectivity is based on the ambient temperature of the instrument. The operational range of the ACMP is between 4-40C.
12/04/2020
|
Recommended NIST Library Processing Method Settings The recommended library search settings when using the NIST library with MasterView™ or SCIEX OS software are listed here and include deactivating collision energy filtering.
12/27/2018
SCIEX OS
|
LibraryView Software
|
MasterView Software
|
Can an Analyst® Software Results Table Be Opened in SCIEX OS Software? No, an Analyst® software results table cannot be opened in SCIEX OS software. The user will have to recreate the Analyst results table in SCIEX OS software.
11/02/2021
SCIEX OS
|
Analyst Software
|
Explore Mode - Extract Ions - Overlay Multiple Panes Automatically Where to find the settings for automatically overlay panes when extracting multiple Ions.
10/23/2017
QTRAP Systems
|
Triple Quad Systems
|
Analyst Software
|
Watson LIMS Needs To Be in Compatibility Mode for Use with SCIEX OS Software When transferring data from SCIEX OS software to Watson LIMS, the Watson software did not appear to be importing the data.
10/30/2020
SCIEX OS
|
What Value Should Be Used for the XIC Width in My SWATH® Acquisition MicroApp Processing Settings? One common error when using the SWATH® Acquisition MicroApp 2.0.1 for processing SWATH data is to relate the XIC width setting in the processing software with the mass accuracy of the instrument, and set the XIC width to a value that is too low. XIC extraction widths should be set to 50 to 75 ppm, regardless of the mass accuracy of the acquired data.
11/10/2020
Academia Omics
|
Pharma CRO
|
SWATH Acquisition
|
How Do I Install the Intact Protein Script on the TripleTOF® 5600 and 6600 Systems? The Intact Protein script can be installed from the Analyst® TF software directory located at: C:\Program Files (x86)\Analyst\Scripts. The ShowInTuneLayout script must be installed and enabled in order to acquire intact proteins.
11/02/2021
Academia Omics
|
Pharma CRO
|
Why are the peaks centroided in ProteinPilot Group files Why are the peaks centroided in ProteinPilot Group files
10/07/2016
Academia Omics
|
ProteinPilot Software
|
How to modify the Project Results Table Settings in Analyst All available project results table settings can be accessed and modified via Tools.
02/28/2023
|
PeakView® Software 1.2 License Code Replacement PeakView® software 1.2 displays an error message indicating that the license is about to expire. The software needs to be reinstalled, and new license code obtained.
08/02/2017
|
Finding the Pulser Frequency in an Acquisition Method Built in Analyst® TF Software In general, the pulser frequency is automatically calculated for a given mass range in the method editor using the Analyst® TF software. To see the pulser frequency value, follow the directions below.
01/12/2018
Analyst Software
|
Can a Method Built in Cliquid® Software Be Converted to a Method for SCIEX OS Software? No, methods built in Cliquid® software cannot be converted for use in SCIEX OS software. Cliquid software method files are not supported in SCIEX OS software. |
Where Can I Find Out If My Software Upgrade Is Free or a Paid Upgrade? To determine if your software upgrade is complimentary, check the SCIEX webpage, Software Product Lifecycle at https://sciex.com/software-support/software-support-policy.
09/14/2017
Software
|
Resetting an Agilent Infinity II LC System after Receiving an ADD Error This article explains how to reset an Agilent Infinity II LC system after receiving an ADD error by clearing the configuration.
10/31/2017
Analyst Software
|
Dionex: Is the DCMS Link 2.10 and 2.12 Compatible with Win7 32- and 64-bit? The DCMSLink is not validated to work with a Win 7 operating system (OS) as stated in the Dionex release notes.
05/16/2018
Analyst Software
|
What Library Database File Types Can Be Imported into LibraryView™ Software 1.4? Many different types of compound and library databases can be imported into LibraryView™ software version 1.4. The following options for source files are acceptable for importing library compounds into LibraryView software: LibraryView Package (*.lbp), DiscoveryQuant™ Compound Database (*.mdb), Analyst® Compound Database (*.mdb), Cliquid® Package (.clq), Excel file (*.xls), Overwrite Database with LibraryView Snapshot (*.lbp), and Third Party Library Package (*.tplp)
04/29/2020
LibraryView Software
|
What Are the Current Limitations of the SWATH® Variable Window Calculator Tool? The SWATH® Variable Window Calculator tool can be used with Analyst® TF 1.7 software and SCIEX OS 1.7 software and higher for many QTOF instruments. This article lists the maximum target number of Q1 windows and the maximum upper m/z limit for each QTOF instrument.
05/27/2022
Academia Omics
|
Pharma CRO
|
SWATH Acquisition
|
What Are the Considerations for Using Ion Pairing Reagents in My Mobile Phases? Ion pairing reagents can greatly help with problematic chromatography, but any added ion pairing reagents also tend to stick to LC components and the column, as well as to the MS source, leading to signal suppression and diminished column performance. This article includes suggestions for a more successful experience when using ion pairing reagents and mass spectrometry.
01/24/2019
|
ProteinPilot error fraglet.exe CHEMICAL EXCEPTION ProteinPilot error fraglet.exe CHEMICAL EXCEPTION
12/07/2016
Academia Omics
|
ProteinPilot Software
|
Connecting to a New Compound Database Library in Analyst® Software The steps needed to connect to a new compound database library in Analyst® Software are detailed in this article.
11/10/2020
Analyst Software
|
Migrating the SQL Server from DiscoveryQuant™ 2.1 Software to Version 3.0.x Instructions are provided here for migrating the SQL server for DiscoveryQuant™ 2.1 to an installation of DiscoveryQuant 3.0.x software.
10/04/2019
Pharma CRO
|
DiscoveryQuant Software
|
Shimadzu 30AC Autosampler External Rinse Method Definitions in Analyst® Software On the Shimadzu 30AC autosampler, the external rinse function flushes the needle's exterior using a solution that is pushed to the rinse port by the rinse pump. When building an LCMS acquisition method in Analyst® software, the rinse method definitions can be accessed through the Flow Channel Reference radio button under the Autosampler tab.
03/13/2018
|
When Does SCIEX OS Sofware Start Archiving Audit Trail Records? In SCIEX OS software, the audit trail will be archived when it reaches 20,000 records.
03/11/2022
Pharma CRO
|
Software
|
Cliquid® Software Does Not Show Quantitation Values for Qualitative Transitions in the Sample List When Cliquid® software is used to submit samples, the sample list shows only the group name instead of each individual transition (e.g., only Testosterone is shown, instead of Testosterone 1 and Testosterone 2) so only one concentration from one transition can be added. To ensure that Cliquid software reads the full transition name, an underscore in between the name and number must be added (e.g., Testosterone_1 and Testosterone_2).
11/10/2021
Cliquid Software
|
Crashing on Windows 7 when in ExploreQuantitate Mode AB Sciex Analyst has stopped working When using Analyst versions 1.6.x with Windows 7 Operating System Analyst will stop with the message AB Sciex Analyst has stopped working. This will usually happen when the mouse cursor is moved across the chromatogram pane.
10/01/2015
Analyst Software
|
Creating a Peptide Library in Skyline with a ProteinPilot™ 5.0 Software .Group File If a user installs ProteinPilot™ 5.0 software with Skyline, old and new group files will not be able to be opened because the converter has changed. An error message will be displayed when building peptide libraries while importing a ProteinPilot group file.
05/15/2018
ProteinPilot Software
|
How Is Quantitation Information Imported into an Analyst® Software Batch? To import updated quantitation information into the batch, export the batch file as a text file from Analyst® software and edit the information in Excel.
05/14/2018
Analyst Software
|
How many processing cores will my ProteinPilot Software use? The number of processing cores used by ProteinPilot Software is defined by the license file and the physical capabilities of the instrument.
03/16/2017
Academia Omics
|
ProteinPilot Software
|
How Do You Select Root Directory for a Workgroup in Analyst® Software 1.6.3? To select a root directory for a workgroup in Analyst® software 1.6.3, the workstations should be removed from the workgroup and then re-added.
09/11/2017
Analyst Software
|
Is ProteinPilot™ Software 5.0.1 Compatible with Windows 10? Is ProteinPilot™ Software 5.0.1 compatible with Windows10? No, it works only with Windows 7, Service Pack 1, 64-bit.
09/11/2017
Academia Omics
|
Pharma CRO
|
QTRAP 5500
|
QTRAP 6500
|
What Normalization Can I Use in MarkerView™ Software 1.3.1 when Processing My Peptide Data? MarkerView™ software 1.3.1 software has a new Most Likely Ratio (MLR) normalization algorithm incorporated info this newest version of the software.
01/26/2022
Academia Omics
|
Pharma CRO
|
MarkerView Software
|
How Do I Configure Analyst® Software for Network Acquisition Network data acquisition can be very useful for data integrity backup security and access purposes. This walkthrough explains how to configure Network Acquisition using Analyst Software.
07/08/2016
Analyst Software
|
Installing the SCIEX OS Software CFR License Save the CFR license file to the C:\ Program Files\Sciex\Sciex OS folder where the SCIEX OS license is located.
04/15/2019
SCIEX OS
|
What is the Maximum Length of the Project Path in Analyst® Software to Submit a Batch Successfully? In Analyst® software 1.7.2, users cannot save or submit an acquisition batch if the name of the project path is longer than 126 characters.
11/03/2021
Analyst Software
|
Resolving SCIEX OS Software Error: Cannot Open LibraryViewServiceHost Service on Computer When trying to access the Analytics mode in SCIEX OS software when logged into Windows as a user without administrative privileges, an error is received: "Error has occurred: Cannot open LibraryViewServiceHost service on computer '.'. LibraryView service must be running." The LibraryViewServiceHost was not started when the Analytics mode was opened, and a workaround needs to be used to launch it.
09/27/2019
SCIEX OS
|
It may be required to reset the values within these files if they have been manually adjusted incorrectly.
10/07/2016
Academia Omics
|
Analyst Software
|
ProteinPilot Software
|
How to Report Regression Parameters in a Results Table Created in SCIEX OS Software Regression parameters values (e.g., r squared, slope, linear coefficient) can now be added to a results table created in SCIEX OS software from the calculated columns that are saved under the processing method.
05/18/2022
SCIEX OS
|
What Are the Specifications of the Six-Protein Mixture Supplied with the iTRAQ® Kit? Specifications of the six-protein mixture (PN 4348363) supplied with the iTRAQ® kit include the accession numbers of the proteins and their mass per tube (in µg and nmol).
01/09/2019
Academia Omics
|
Pharma CRO
|
iTRAQ Reagent
|
Returning the Status Column to the Analyst® Software Queue Manager To bring back the status column to the Analyst® software Queue Manager, right click in any column of the Queue Manager and select Column Settings.
07/03/2018
Analyst Software
|
Changing the Leak Sensor Detection Detector Threshold for a Shimadzu LC System When a leak error is observed for a Shimadzu LC system but the channel is dry, it may be that the threshold for detecting a leak is set too low.
06/01/2018
|
When opening a reporter 3.0.1 XML Template in Microsoft Word 2007 SP1 then the error message The file contains custom XML elements which are no longer supported by Word. If you save this file these custom XML elements will be removed permanently
10/01/2015
Analyst Software
|
Overview of the 32 Karat Software User Privileges An overview is provided of each user privilege in the 32 Karat software that can be assigned or removed from the user.
04/02/2019
PA 800 Plus Pharmaceutical Analysis System
|
How Do I Prevent a Windows 10 Upgrade on my SCIEX Windows 7 Desktop Microsoft has started to strongly encourage users to upgrade from the Windows 7 operating system to the Windows 10 operating system. This action might result in an unwanted or accidental upgrade. As of July 2016 none of the SCIEX software products have been fully tested on the Windows 10 platform. We cannot confirm therefore that the SCIEX software will perform as expected on the Windows 10 operating system.
07/05/2016
|
Can Google Drive Be Used for Transferring or Storing Data Generated by SCIEX Software? The use of Google Drive for data storage has not been tested with data sets generated on SCIEX software. Transferring and storing data using Google Drive has led to issues with data sets for some end-users because of a potential embedded encryption process in Google Drive.
09/10/2019
Software
|
Analyst® 1.7 Software License Error: Cannot Find License File After activating the Analyst® 1.7 software license and saving it to C:/ProgramData/AB SCIEX/Analyst/License, the software would still not activate and error message -1,359 was received. Retyping the license file name to "Analyst1.7.lic" resolved the issue.
05/03/2018
Analyst Software
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AB SCIEX Data Explorer® Software Issue: Periodic Table and Other Software Features Are Grayed Out The AB SCIEX Data Explorer® software is an embedded software for data processing on the 4800 MALDI TOF/TOF™ and the TOF/TOF™ 5800 Systems and was recently rebranded; however, the rebranding process caused certain applications menu items to become grayed out (periodic table, isotope calculator, and elemental composition). To resolve this issue, install the patch provided in the link in this article.
11/14/2019
Academia Omics
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Where is the method found that is created during automatic compound optimization? When several compounds are optimized in Analyst 1.6.3, one method is created with all the MRM transitions included. The final MRM method created contains all compounds and is present at the bottom of the compound optimization report.
03/20/2017
Analyst Software
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Upgrading Analyst® Software Requires that Cliquid® Software be Uninstalled Upgrading Analyst® software on workstations where Cliquid® software is also installed requires that Analyst be uninstalled as well as Cliquid software. After reinstalling Analyst software, then Cliquid can be reinstalled.
10/17/2018
Software
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Adjusting Integration Parameters to Exclude Peak Tailing Area in Analyst Some analytes may display an undesirable amount of peak tailing, some of which may need to be excluded from the total integrated peak area. Adjusting the percent noise parameter in the IntelliQuan dialog may help to decrease the area of the peak included for integration.
09/06/2018
Analyst Software
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How to Simulate a Hardware Profile with a Mass Spectrometer and Shimadzu LC in Analyst® Software In Analyst® software, creating a simulated hardware profile allows a user to create acquisition methods and batches when using the software on a processing PC that is not connected to an instrument. To create a simulated hardware profile, open the Hardware Configuration Editor and select a hardware profile that you would like to simulate. Then select Edit Profile.
11/02/2021
Analyst Software
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PA800 How To - Replacing the Ejector and Electrode Replacing the Ejector and Electrode
05/02/2017
Pharma CRO
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PA 800 Plus Pharmaceutical Analysis System
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How Are Analytes Deleted from a Processing Method in Sciex OS Software? To delete unwanted analytes from a processing method in Sciex OS software, highlight the rows, right click and select Delete Rows.
10/03/2019
SCIEX OS
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Coolant leak troubleshooting tips The document provides troubleshooting steps for coolant leak issues (to determine where the leak is coming from).
04/05/2019
PA 800 Plus Pharmaceutical Analysis System
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Why Is There No MRMHR Scan Type when Using the Method Wizard for a TripleTOF® LC-MS/MS System? This article describes the MRMHR workflow for a TripleTOF® LC-MS/MS System using the Method Wizard in Analyst® TF or SCIEX OS Software. MRMHR is not a scan type. It is a description for a set of looped experiments, which can be used for a targeted approach. The looped experiments include a TOF-MS experiment followed by dedicated product ion experiments either in high-resolution or high-sensitivity mode.
12/05/2021
Academia Omics
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Environmental Industrial
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Food and Beverage
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Forensics
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QTOF Systems
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Unable to Open SCIEX Cloud ProteinPilot™ Software Searches with the Desktop Version 5.0.2 The version of ProteinPilot™ Software in the SCIEX Cloud is version 5.0.3; therefore, group files created in the SCIEX Cloud cannot be downloaded to a desktop and opened in ProteinPilot Software 5.0.2. To download and read a group file on a desktop installation of ProteinPilot Software, the desktop version must be upgraded to version 5.0.3.
11/10/2020
Academia Omics
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Pharma CRO
|
ProteinPilot Software
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How to create a new Wellplate in SCIEX OS for Agilent Autosampler Will explain how to use an existing wellplate to modify accordingly to be able to use a new customized wellplate for Agilent Infinity II Multisampler. Same procedure will also works for other Agilent Autosampler, but have some slightly different names for some of the steps.
08/04/2022
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Is It Possible To Set the Y-Axis to a Fixed Value in Analyst™ Software? When reviewing data in the Analyst™ software Explore mode, the y-axis for the signal intensity cannot be set to a fixed value to compare results from one run to another. But this can be done in Quantitate mode while reviewing peaks in a results table by selecting Tools -> Settings -> Peak Review Settings and typing in the Intensity under Automatic Zooming -> Y axis units.
03/06/2018
Analyst Software
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DiscoveryQuant™ Software Will Not Launch Without Analyst® Software Installed If DiscoveryQuant™ software fails to launch, even after the software is uninstalled and reinstalled, check to see if Analyst® software is also installed. An installed version of Analyst software is a prerequisite to installing DiscoveryQuant software; DiscoveryQuant software will not launch without Analyst software.
05/13/2020
DiscoveryQuant Software
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Why Won't LipidView™ Software Load My Analyst® Software (.wiff) Data Files? In order to load Analyst® software data files (.wiff files) into LipidView™ software, either Analyst or Analyst TF software must be installed alongside LipidView.
06/11/2020
Academia Omics
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Pharma CRO
|
LipidView Software
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Can Audit Maps Be Easily Transferred from Analyst® Software to SCIEX OS Software? No, audit maps cannot be directly transferred from Analyst® to SCIEX OS software.
05/18/2022
Pharma CRO
|
Software
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Can the SWATH™ Acquisition Variable Window Calculator v 1.0 Be Used with All TripleTOF® Systems? SWATH™ acquisition software and the variable window methods will work on the TripleTOF® 4600, 5600 and 6600 systems, but Analyst® TF 1.7 software must be installed.
12/15/2017
Analyst Software
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SWATH Acquisition
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How Can Concentrations above the ULOQ be Flagged in MultiQuant™ Software? Concentrations above the ULOQ can be flagged in your MultiQuant™ software results table by setting up the Upper Limit of Calculated Concentration in the Quant method.
06/08/2017
Software
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Analyst: How is the limit on the number of samples in the queue increased? The limit on the number of samples added to the queue for a run can be adjusted using the Max. Num. Waiting Samples setting in the Queue Options menu.
04/04/2017
Analyst Software
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Exporting .T2D Files in Batch Mode from the Raw Data Spotset To export .T2D files in batch mode from the raw data spot set on a MALDI plate, locate the Remote Data Access software in the program files and install the T2DExporter.
06/04/2018
Academia Omics
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Pharma CRO
|
Adding User Groups to the Analyst® Software Secruity Configuration The steps below describe how to add user groups into the Analyst® software security configuration.
03/08/2018
Analyst Software
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Does the Echo MS System Support All QTRAP® 6500+ System Functionality? The Echo® MS System cannot be supported by the QTRAP® 6500+ System; instead, Echo MS is paired with the TripleQuad 6500+ System for data acquisition.
10/30/2020
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If the dilution factor is not set correctly in an Analyst® software results table, the calculated concentration values for samples of known concentration will be incorrect.
11/07/2019
Analyst Software
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Firewalls Can Cause CloudConnect Connection Issues The CloudConnect service is installed and runs in the SYSTEM security context, as opposed to PeakView which runs in user context. Some IT organizations block port 443SSL for SYSTEM level programs as a security measure.
06/01/2018
PeakView Software
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SCIEX OS Software: How to Choose the Format for a Numerical Field in a Report By default, the format for a numerical field in a report is taken from the results table itself if the format is not set in the report template tag. If a specific numerical format is desired for a particular field in a report, certain default formats (such as the number of decimals desired or scientific notation) can be chosen in the Format field in the tag for that value. Otherwise, In the SCIEX OS software results table itself, the number format can be set for individual columns by editing the Number Format in the Results Table Display Settings options.
11/09/2019
SCIEX OS
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Analyst Software
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MultiQuant Software
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Is it possible to export the correlation coefficient r from a MultiQuant results table This article gives a guidance how to export the correlation coefficient r from a MultiQuant results table. Only Available in MultiQuant Version 3.0.1.
09/04/2016
MultiQuant Software
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How to Print an XPS Report after Running MS Tune in SCIEX OS Software To print the XPS report from the most recent or a prior tuning in SCIEX OS software, navigate to this location: D:\SCIEX OS Data\Optimization and then print the file report.xps.
12/15/2021
SCIEX OS
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Aliquots of Bulk iTRAQ® Reagent Require Cold Storage Under Inert Gas When aliquoting bulk iTRAQ® reagent, vials must be stored at -20 °C under inert gas.
11/09/2019
Academia Omics
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Pharma CRO
|
iTRAQ Reagent
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How to Adjust Failed Ion Ratios in MultiQuant® Software If the ion ratios are flagged in the MultiQuant® software results table, it usually indicates that there is some discrepancy in the integration of the peaks corresponding to the transitions used for that analyte group.
09/06/2018
MultiQuant Software
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Details of the requirements to run AAO HPLC Device with Analyst 1.5.1 and 150 Transitions.
09/04/2016
Analyst Software
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How Are Calibration and Integration Parameters Defined in MultiQuant™ Software? The default integration parameters are defined in the User Integration Defaults or User Units & Calibration Defaults under the Edit menu in MultiQuant™ software. These settings should be established before creating a quantitation method.
06/01/2017
Software
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What Version of LibraryView™ Software Is Needed for a Win 7 64-bit System? Install LibraryView™ software version 1.0.2 for use with Windows 7, 64-bit systems.
12/21/2017
LibraryView Software
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What Is the Settling Time in an Analyst® Software Acquisition Method? In Analyst® software, the settling time is defined as the time that a mass spectrometer pauses after finishing a cycle until it begins the next cycle. The instrument electronics require a settling time in order to function successfully.
11/09/2019
Mass Spectrometers
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How to install ProteinPilot 4.5b and upgrade from ProteinPilot 4.0 to ProteinPilot 4.5b This procedure describes the removal and install of ProteinPilotTM software 4.5b in great detail.
09/04/2016
Academia Omics
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ProteinPilot Software
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Eliminating air bubbles in CEQ/GeXP gel cartridges Centrifuge protocol to help get rid of air bubbles in gel cartridges that might get into the gel lines
04/04/2019
GenomeLab GeXP Genetic Analysis System
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Yes, the SCIEX OS Software Central Administrator Console (CAC) software installed on a Windows Server 2019 will run in a virtual environment and is officially supported.
10/12/2022
Pharma CRO
|
SCIEX OS
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Difference between Rapid and Thorough Searches in ProteinPilot™ Software The rapid search and a thorough search settings in ProteinPilot™ software determine which parts of the search algorithm will be invoked and effectively how deep the sample will be searched to find the right answers.
11/02/2018
Academia Omics
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Pharma CRO
|
ProteinPilot Software
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The Audit Trail settings in Analyst software enforce that all manual integrations have to be Accepted. If you do not require the Audit Trail you can turn off this requirement by setting the audit map to No Audit Trail.
11/15/2017
Analyst Software
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How Are Simple Queries Created in MultiQuant™ Software? Simple queries can be created in MultiQuant™ software by selecting the Create Simple Query option in the Process menu. The formula can then be entered into the Create Query File screen.
07/14/2017
Software
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Analyst® 1.7 Software Installation Guide The Analyst® 1.7 Software Installation Guide is attached. Please consult this guide before installing this version of Analyst software on your PC.
04/10/2018
Analyst Software
|
Permanent License Gives an Error Message of Expired for DiscoveryQuant™ Software After launching DiscoveryQuant™ software, an error message is received indicating the software has expired even though a permanent license is installed.
10/19/2018
Software
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How Is an Ion Library Created in Analyst® Software? To create an ion library in Analyst® software, each MS or MS/MS spectrum needs to be opened and then added to a small existing database.
10/30/2017
Analyst Software
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Where Are the Event Logs for SCIEX OS Software Archived? When event logs in SCIEX OS software become too large, the software will create an archive event log file. This file is located in the directory C:\ProgramData\SCIEX\Clearcore2.Acquisition.
10/30/2020
SCIEX OS
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Where Are the MPX™ Driver Software Event Logs Located? To locate the MPX™ Driver software event logs, navigate to the MPX Driver folder in Program Data and locate the Log folder.
10/31/2017
MPX Software
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What is the IP Address Used by the Uniprot Server to Submit a ProteinPilot™ Software 5.x Search? This article describes the website links that are being used to submit a ProteinPilot™ software (v 5.x) search.
09/13/2017
Academia Omics
|
ProteinPilot Software
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DiscoveryQuant™ Software Produces SQL Error during Migration from Windows 7 to Windows 10 To resolve an error that prevents the SQL database from connecting with DiscoveryQuant™ software 3.0.2 in Windows 10, SQL user accounts with the password enabled must be used.
12/15/2021
DiscoveryQuant Software
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What Paramters Can Be Modified in the Non-targeted Peaks Search Algorithm in SCIEX OS Software? The non-targeted peak searching algorithm determines which peaks are included for further library or formula finder searches in the Analytics mode of SCIEX OS Software, and the parameters that can be modified are described here.
04/17/2019
SCIEX OS
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Recommended N-Glycan MALDI Sample Preparation Matrices for TOF/TOF Instruments Depending on what type of N-glycan moiety that is being analyzed on a TOF/TOF system, refer to the table provided for recommended MALDI sample preparation techniques, matrices and acquisition methods.
10/18/2018
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Can the SCIEX QTRAP® or TripleQuad™ 7500 LC-MS/MS System Operate without E Lens™ Technology Active? Yes, the SCIEX QTRAP® or TripleQuad™ 7500 LC-MS/MS Systems can operate without the E Lens™ Technology active. Each QTRAP and TripleQuad 7500 System comes with a blanking plug that can be inserted should there be a need to operate without the E Lens Technology.
11/06/2020
QTRAP Systems
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Triple Quad Systems
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Adding or Removing Samples from the SCIEX OS Software Results Table Open a results table in the Analytics workspace in SCIEX OS Software. Select the More menu > Add samples. In the Select Samples dialog, select the required samples.
11/04/2021
SCIEX OS
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Analyst® Software Error Message: Failed To Set Sample Data If the error message "Failed to set sample data" appears when using Analyst® software, the issue may be resolved by reducing the number of racks in the batch to only those that were actually used for samples.
05/17/2019
Analyst Software
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Diverter Valve Would Not Work While Using Delay Time in Analyst® Software The diverter valve will not work properly when using Delay Time in the acquisition method of Analyst® Software due to a mismatch between diverter valve timing and MS acquisition timing. This results in the diverter valve timing not aligning with the MS acquisition time.
12/02/2022
SCIEX OS
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Mass Spectrometers
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Analyst Software
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Lost sensitivity on your Triple Quad or QTRAP You may need to optimize your CEM detector parameter. This article explains how to resolve the issue of low sensitivity on a Triple Quadrupole or QTRAP instrument due to an incorrect CEM value by manually optimizing the CEM detector parameter in the Analyst software
09/29/2017
QTRAP Systems
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Triple Quad Systems
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Installing MultiQuant® Software Generates a .NET Framemwork Error When installing MultiQuant® 3.0.2 software on Windows XP, an error message was received: "An error occurred while installing system components for MultiQuant. Setup cannot continue until all system components have been successfully installed."
05/31/2018
MultiQuant Software
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How Are Submitted Batches Rearranged in the Analyst Queue? Batches can be rearranged in the Analyst software queue using the Move Batch option. In the Move Batch window, drag the batch to be moved to the desired location to rearrange.
04/17/2017
Analyst Software
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Can the Existing Ion Source on the X500R QTOF System Be Converted to APCI? The source on the X500R QTOF System can be used in atmospheric-pressure chemical ionization (APCI) mode, but a different probe with a twin electrode must be installed. In addition, a different APCI tuning solution must be used and is available for purchase from SCIEX.
02/16/2021
Environmental Industrial
|
Food and Beverage
|
PA800 How To - Uninstalling the LIF Detector Uninstalling the LIF Detector
05/02/2017
Pharma CRO
|
PA 800 Plus Pharmaceutical Analysis System
|
Formatting Analyte Names in an Analyst® Software Quantitation Method When formatting analyte names in an Analyst® software quantitation method, they should not contain any dashes. A space should be used to separate analyte names and numbers in the quantitation method to correctly group analytes.
10/16/2018
Analyst Software
|
Calibration Correction Factor (CCF) for Laser-Induced Fluorescence (LIF) Calibration The Calibration Correction Factor (CCF) for laser-induced fluorescence (LIF) calibration is the mathematical relationship between the fluorescence from a known concentration of the analyte and the associated signal detected by the instrument. An explanation of how it is calculated is provided in this article.
04/23/2019
PA 800 Plus Pharmaceutical Analysis System
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PA800 How To - Removing the Ejector and Electrode Removing the Ejector and Electrode
05/02/2017
Pharma CRO
|
PA 800 Plus Pharmaceutical Analysis System
|
Convertingt MS data from .Wiff Format to a .Mgf File To use different search engines/software, .wiff data must be converted to different format such as .mgf file before being able to submit the data for a search.
06/04/2018
Software
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Patch for the Analyst® TF Software 1.7.1 Noise Sync Signal Issue This patch addresses a defect in Analyst® TF software 1.7.1 that causes occasional acquisition failures resulting in the warning “Noise failing sync signal ignored" being reported in the application log file (ATF-665, -TDC error).
12/13/2017
Analyst Software
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MultiQuant™ MD Software Will Not Launch from Desktop MultiQuant™ MD software will not launch if the Analyst® software security setting is set to Integrated or Mixed mode. To keep these security settings, launch MultiQuant from the Companion Software mode in the left-side vertical menu in Analyst. Otherwise, change the security settings to single-user mode to open MultiQuant MD from the desktop.
06/01/2017
Software
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Can ProteinPilot™ Software Version 5.0.2 Be Installed on a 2019 Server? Yes, ProteinPilot™ software 5.0.2 can be run on a Windows 2019 Server. This was not officially tested or mentioned in the release notes, but many users have installed the Windows 10-compatible ProteinPilot software 5.0.2 on the Windows Server 2019 operating system and have run the software successfully in this environment.
11/02/2021
Academia Omics
|
ProteinPilot Software
|
Calculating Molecular Mass for Compounds with Isotopes in SCIEX OS To calculate the molecular mass of compounds containing isotopes in SCIEX OS, select the Mass Calculators in the Explorer mode and then specify the chemical formula for the Mass Property tab. For isotopes, precede the chemical symbol with the weight of the isotope.
07/03/2018
SCIEX OS
|
Setting up a Rack Changer in Sciex OS Simulation Mode To set up the RackChanger in Sciex OS in simulation mode, go to Devices under Configuration mode. Select Add and choose Integrated System and follow the directions below.
03/22/2018
SCIEX OS
|
How to get the error log from inside a Shimadzu CBM for a VIERROR Description of how to access the Shimadzu Web server which can help to diagnose errors
11/01/2018
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How to deal with the Analyst User Registration Pop-Up-Window When freshly installed and not yet registered Analyst asks in a pop-up-window for a Registration Key. Here is shown where to get it.
05/31/2017
Analyst Software
|
Which Software License Is Used for LibraryView™ 1.2 Software Installed with SCIEX OS 1.3? When installing LibraryView™ 1.2 software alongside SCIEX OS 1.3, use a LibraryView 1.0 license, PN 5022277.
12/21/2017
SCIEX OS
|
LibraryView Software
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Error In MultiQuant™ Software When Generating a CSV Report The error "Cannot save report with graphical or table elements as a text/csv file" appears when attempting to generate a report as a CSV file in MultiQuant™ software using a report template that has figures, pictures, or tables. This is due to CSV reports not being able to display figures or tables.
12/02/2022
MultiQuant Software
|
DiscoveryQuant™ 3.0.1 Software HotFix 2 Gives Not Registered Error Despite being properly registered, DiscoveryQuant™ 3.0.1 software with hotfix 2 gives the error message that it is not registered and must quit. The root cause of this error is the presence of multiple instances of DiscoveryQuant software installed on the same PC.
09/10/2019
DiscoveryQuant Software
|
How to Activate the Molecule Profiler Software Module in SCIEX OS Software The Molecule Profiler software is a processing-only software module within the SCIEX OS software suite that can identify and characterize parent molecules and their metabolites. Activating the Molecule Profiler software version 1.1 simply requires the installation of an additional license; however, activation of version 1.0.1 requires an additional software download as well as license installation.
06/17/2022
Academia Omics
|
Forensics
|
Pharma CRO
|
MetabolitePilot Software
|
Creating a Hardware Profile for the Agilent Infiniti II LC System and a SCIEX 6500+ System How is a new hardware profile created that contains a 6500+ system and an Agilent Infinity II LC system that is using the Analyst Device Driver software?
03/23/2017
Triple Quad 6500
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Installing the Accurate Mass Metabolite Spectral Library 1.0 Installation of the Accurate Mass Metabolite Spectral Library 1.0 requires a valid license file in order to install the compound database. The library installer creates a folder for the Accurate Mass Metabolite Spectral Library in the Start > All Programs > AB SCIEX > Accurate Mass Metabolite Spectral Library folder. The library and user documentation are copied into this location.
08/09/2019
LibraryView Software
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Ion Ratios Are Not Calculated as Expected in MultiQuant™ Software The ion ratio value was not showing correctly due to a blank sample being included as one of the calibrators in MultiQuant™ software.
06/01/2018
MultiQuant Software
|
Scheduled ionization in Analyst® TF software 1.8 is not configured to work optimally with the OptiFlow® Turbo V ion source ion source for nano flow. When using the OptiFlow® Turbo V ion source, scheduled ionization is always on, except when the start time in Analyst software is set to zero during pre- and post-run times. This is an issue for the nano spray users, because they will be unable to have the voltage stay on between runs for perpetual spray.
12/06/2021
Academia Omics
|
Analyst Software
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Can I Use Windows Experience Enhancers on My SCIEX Acquisition and Processing PCs? Some PC users prefer different views and/or functionalities in the new Windows 10 interface. There are freeware/shareware programs available that allow for the customization of Windows features (such as emulation of Windows Classic settings). However, these types of Windows accessory programs have not been tested with SCIEX software; their use is not supported.
11/10/2020
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Why Does the Checksum Invalid Error Appear when Processing Data in MultiQuant™ MD Software? If the checksum invalid error appears while trying to process data with MultiQuant™ MD software, this indicates that the data was not previously acquired with checksum feature turned on in Analyst® MD software.
11/09/2018
MultiQuant Software
|
After Activating My Software License Key, the License File Was Not Emailed to Me After the software license key was activated online at the SCIEX website, the license file was not emailed to the registered email address. This occurs when the email address is not entered correctly.
06/01/2017
Software
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Changing the Orienatation of Peak Review Chromatograms in a Reporter Template If the peak review chromatograms are showing in the wrong orientation on an Analyst® or MultiQuant™software report, the page orientation for the actual Word document template may be set to portrait rather than landscape.
12/28/2018
SCIEX OS
|
Analyst Software
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MultiQuant Software
|
Setting Up Email Notifications for Reports in Cliquid® Software To allow the system to deliver email notifications of reports generated in Cliquid® software, select Run Samples. In the menu option Set report options, users can choose to set up the email notifications for completed reports or indicate their preference to have a pdf version of the report emailed to them directly.
04/16/2020
Cliquid Software
|
Replacing a Trial License with a Permanent License When opening a program, an error message may appear that indicates that the license has expired, even when a permanent license is thought to be installed. For these cases, the trial license may still be installed in program files and will need to be removed and replaced with the permanent license.
12/21/2017
Software
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Searching an EST or Other Nucleotide Databases in ProteinPilot™ Software Searching an EST or other types of nucleotide databases in ProteinPilot™ software requires that the database be translated first.
12/27/2018
ProteinPilot Software
|
How Do You Setup a Solenoid or Solvent Selection Valve on a Shimadzu LC? This article describes how to setup a FCV-11 AL valve for a Shimadzu LC system.
11/22/2017
Clinical
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Setting Up a New Project in Analyst® Software To set up a new project in Analyst® software, navigate to the Tools menu and select Project.
10/25/2019
Analyst Software
|
Where Do I Put Query Files Used with Reporter Templates for MultiQuant™ or SCIEX OS Software? Queries are used by report templates to process specific data from results tables in either MultiQuant™ or SCIEX OS Software. For a report template to utilize a query, the query file must be placed in the same directory as the report template.
09/30/2022
SCIEX OS
|
MultiQuant Software
|
Can the Existing Ion Source on the X500R QTOF System Be Converted to APCI? The source on the X500R QTOF System can be used in atmospheric-pressure chemical ionization (APCI) mode, but a different probe with a twin electrode must be installed. In addition, a different APCI tuning solution must be used and is available for purchase from SCIEX.
02/16/2021
Environmental Industrial
|
Food and Beverage
|
Decreasing Run Time when Using the LCMS Reconstruct Algorithm in ProteinPilot™ Software This article describes how to modify the configuration file for ProteinPilot™ software to decrease the time needed when using the LSMS Reconstruct algorithm, especially when performing large protein ID searches on data sets from a TripleTOF® 6600 LC-MS/MS System.
12/05/2021
Academia Omics
|
ProteinPilot Software
|
What is the Signal-to-Noise(S/N) Integration Threshold in SCIEX OS Software? A signal-to-noise (S/N) integration threshold was introduced in SCIEX OS software version 2.1.6, which allows users to select peaks for integratin based on the S/N ratio.
12/05/2021
SCIEX OS
|
Using an Older Version to Open a Processing Method Created in a Newer Version of SCIEX OS Software The files created in SCIEX OS Software are not backwards compatible with other versions of the software. An error will appear when a processing method created with a higher version of SCIEX OS Software (e.g., 2.0) is opened with a previous version of SCIEX OS Software (e.g., 1.7). To open a processing method created in the latest version of SCIEX OS Software with the older version, export the processing method as a text file.
12/02/2020
SCIEX OS
|
Resolving the Analyst® Software 1.7 Error: Feature Has Expired The licensing error, Feature has expired, appears when Analyst® software 1.7 is launched. This article explains how to replace the license file to resolve the error.
10/28/2020
|
How To Change Chromatography Peak Shading In MultiQuant™ Software To change how peaks are shaded in MultiQuant™ software in the Peak Review section, right click on the chromatogram and click on Options. Under the Appearance tab, there will be a drop-down section for Fill Peaks.
09/16/2022
MultiQuant Software
|
Extra Backslashes Added when Using Network Location for Root Directory in Analyst® Software If extra backslashes are added to a network location for a root directory for Analyst® software, a registry edit will be needed to prevent this issue from continuing to occur. The extra backslashes in the data file name can cause errors when trying to create a new project or save files (including results tables).
12/15/2021
Analyst Software
|
Analyst® Software Scheduled MRM Acquisition Failure Due To Unprogrammed Diverter Valve Scheduled MRM acquisition methods created in Analyst® software may fail to start if there is a diverter valve in the hardware profile. Ensure that that valve has a time table program or that it is removed from the method's hardware profile.
03/14/2018
Analyst Software
|
Maintaining LCMS Systems under Specified (Standby) Conditions Post-Acquisition in Analyst® Software You can choose what happens to your system after the last sample in your queue has been acquired in Analyst® software.
02/28/2019
Analyst Software
|
Analyst® 1.7 Software License Error: No Such Feature Exists. Feature: Analyst.acquisition To resolve the Analyst® 1.7 license error "No such feature exists. Feature: Analyst.acquisition", the license key made need to be replaced. This error occurs when a processing license is installed on an acquisition workstation.
04/12/2018
Analyst Software
|
Error in SWATH MicroApps: Window Widths below 4 Da Are Not Supported This error will appear if the SWATH configuration file is not edited to allow for window widths below 4 Da.
05/15/2018
Academia Omics
|
How to adjust, save and export the table settings in an Analyst Quantitation Table Instructions how to modify (choose and adjust the visible columns, change the significant figures and notation), save and export an Analyst Quantitation Table.
11/01/2018
Academia Omics
|
Clinical
|
Environmental Industrial
|
Food and Beverage
|
Forensics
|
Pharma CRO
|
Mass Spectrometers
|
Analyst Software
|
Issue when Exporting and Importing Text Files into MultiQuant or SCIEX OS Software Excel can insert extra characters in exported forms of the MultiQuant™ or SCIEX OS software data and corrupts this data; the resolution here is to edit the exported file and use another editor, other than Excel, that does not insert extra characters into text.
10/19/2020
|
Mimic 'Inject Ahead' Autosampler By Altering Your Programmed Gradient Profile HPLC cycle time can be decreased by using inject ahead mode on autosamplers. This article explores the effect of using this mode and defines how the same result can be achieved without the requirement for inject ahead mode.
04/21/2017
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How Is Relative Retention Time Calculated? For analytes using an internal standard, the actual retention time (RT) of the internal standard peak (for the corresponding sample) is first determined. The expected RT for the analyte is determined by multiplying the specified expected RT by the ratio of the actual to the expected RT for the internal standard.
12/02/2020
MultiQuant Software
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To Prevent Contamination, Use Formic Acid Ampules To prevent your samples from becoming contaminated, use formic acid from small volume ampules rather from a large bottle. Impurities can accrue when taking aliquots of formic acid multiple times from the same bottle, and these impurities can impact positive ion analysis especially.
12/28/2018
Standards and Reagents
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Location of the Audit Trail Archives in Analyst® Software When the Instrument Audit Trail or a Project Audit Trail in Analyst® software reaches 1000 records, a final record stating that the file has been archived is added. The audit trail is automatically saved in the Project Information folder with a name indicating the type of audit trail and the date and time.
10/31/2017
Analyst Software
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Troubleshooting the ZenoTOF 7600 System: Tuning and Calibration Before using the ZenoTOF 7600 system, users should run a system check to verify their instrument's performance. In the event that the MS Quick Status check fails, a link to a troubleshooting guide is included in this article.
12/02/2022
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How to Add Compound Information to LibraryView™ Software 1.1 To add information about a compound to LibraryView™ software 1.1, expand the Compounds list in the Manage pane to begin adding the compound name, and then follow the directions provided.
05/21/2018
LibraryView Software
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How Do I Change the Significant Figures of Regression Equation in Analyst Description of how to change the display of the regression equation in Analyst
10/01/2015
Analyst Software
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Location of the Queue Option Tab in Analyst® 1.6 Software To find the queue option tab in Analyst® 1.6.x software, click on configure mode and then click on the Tools menu, then select Settings and then click on Queue Options.
05/25/2018
Analyst Software
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MasterView™ Software Report Error: Object Reference Not Set to an Instance of an Object When creating are report in the PeakView®/MasterView™ Software suite, the following error appears: "Object reference not set to an instance of an object." This error occurred because a file other than a report template was selected during the create report process.
11/10/2020
MasterView Software
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Tips and Tricks for Cation-Exchange Chromatography for the iTRAQ® Protocol The manual injection procedure for the iTRAQ® protocol requires a 22-gauge syringe with a 2-inch needle (purchased separately). This article lists some tips and tricks on how to set up the syringe when using cation-exchange columns for samples treated with the iTRAQ reagent.
12/08/2017
Academia Omics
|
Pharma CRO
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iTRAQ Reagent
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Chemoview™ software error after data processing "Programmatic access to Visual Basic project is not trusted" can be resolved by turning on the access to the VBA object model from any automation client.
01/12/2018
ChemoView Software
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C Drive Free Space Requirements when Using SCIEX OS Software SCIEX OS software performs best when 20 GB of free space is available on the C drive (C:). Furthermore, SCIEX OS software creates log files in order to monitor both instrument (on an acquisition PC) and software (on both acquisition and processing PC's) performance. These log files incremently increase and can accumulate to a total size of 35 GB. This sets a limit of 55 GB of space needed on the C drive to use SCIEX OS software optimally.
05/14/2020
SCIEX OS
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Can I convert t2d files to mzxml file using 4700 data Can I convert t2d files to mzxml file using 4700 data
10/07/2016
Academia Omics
|
What Type of Analyst® Software Data Is Used with Keystone™ Converter Software? Keystone™ converter software will convert nominal mass .wiff1 files from Analyst® software 1.4.1 and later versions.
11/02/2021
Analyst Software
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Activating Markerview 1.2.1.1 Software Requires an Activation Key Code, Not a License File Installing Markerview 1.2.1.1. requires an activation key code, not a license file. Software activation key codes can be obtained by emailing metabolomics@sciex.com.
11/14/2017
MarkerView Software
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How to Import LibraryView Snapshot File If reinstalling software or moving to different hardware it may be required to import a snapshot file.
12/07/2016
Environmental Industrial
|
Food and Beverage
|
Forensics
|
MasterView Software
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Antivirus Software Symantec v12.x Interferes with Data Acquisition with Analyst® Software Antivirus software can disrupt data acquisition with Analyst® software, Analyst TF and related SCIEX software programs such as DiscoveryQuant™, Cliquid®, LightSight®, Reporter, and MultiQuant™ software. This article provides guidance on how to configure the antivirus software to avoid conflicts with Analyst® software that could cause data acquisition issues.
09/18/2017
Analyst Software
|
Sciex OS 1.3 Error "Services Cannot Launch" Due to Windows 10 Incompatibility An error message is received when trying to launch SCIEX OS 1.3 that indicates that services cannot start. Ensure that the software is installed on a Windows 7, not Windows 10, operating system (OS). Only SCIEX OS version 1.4 and greater are compatible with Windows 10 OS.
12/27/2018
SCIEX OS
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How to Update Retention Times in Sciex OS To update the retention time (RT) of an analyte in Sciex OS, open a results table consisting of grouped components with different RTs, and then follow the instructions provided below.
05/03/2018
SCIEX OS
|
Does the Mascot.dll script work with Analyst 1.6 on a win 7 PC Defines the issues and workarounds required to use the script.
07/08/2016
Academia Omics
|
Software
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Multiquant 3.0.x Installation Fails. No .NET Framework 3.5 SP1 on Windows 7 Multiquant 3.0.x installation is not able to proceed on Windows 7 Operating system because the installation of .NET framework is not completed despite the inclusion of this framework within the Windows 7 Operating System.
10/01/2015
MultiQuant Software
|
Magnifying Chromatogram Peaks Displayed in a SCIEX OS or MultiQuant™ Software Report The chromatograms of peaks that are displayed in a report generated in SCIEX OS or MultiQuant™ software will retain the format of the original peaks displayed in the peak review pane. To magnify the peaks displayed in a report, the zoom settings will need to be changed in the peak review settings for MultiQuant or SCIEX OS software.
11/02/2021
SCIEX OS
|
MultiQuant Software
|
What Is the Peak Split Algorithm when Using a Marker Peak with the Echo® MS System? The marker well in the Echo® MS System is defined by the user in the acquisition batch to generate a special barcode pattern at the beginning and end of the plate run. The barcode is a pattern composed of a narrow peak, then a pause, a wide peak, then a pause, followed by a narrow peak.
11/02/2021
SCIEX OS
|
Troubleshooting retention time shifts and variable pump pressure Instructions for performing flow tests on Shimadzu Nexera and EXION AD HPLC pumps and troubleshooting common causes of inadequate pump flow.
03/20/2017
ExionLC AD
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Delete Rights Are Not Needed to Save or Overwrite a PDF Report in Analyst® Software 1.7.2 In Analyst® software 1.7.2, delete rights are not needed to save or overwrite a PDF file to the folder where the original PDF report is saved.
11/03/2021
Analyst Software
|
Library Hits Are Missing from the Library Search Reports in Analyst® Software When using the library search report templates in Analyst® software, the library hits or the name of the compounds that has a library match does not show up in the report. This is due to an IF statement present in the pre-installed, standard, library-search templates that checks if the library hit is greater than zero ($Libs_Max_Hit_Count>0).
11/04/2021
Analyst Software
|
Separating Two Experiments Acquired within One Period in Analyst® Software Data from two or more experiments acquired within one period in Analyst® software can be separated by opening a data file in Explore mode and double clicking the green arrow.
03/15/2018
Analyst Software
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Installing a License for BioTool Kit in PeakView® Software 2.2 BioTool Kit software is a software module within PeakView® 2.2 software that needs to be activated by a separate license. To install a BioTool Kit license, open PeakView 2.2, navigate to the Help menu, and select BioTool Kit Activation.
05/15/2018
Bio Tool Kit Software
|
Analyst.exe Unable To Locate Component pt95FKn71.dll When Launching Analyst or Activating a Hardware Profile you receive the message Analyst.exe Unable To Locate Component with message body This application has failed to start because pt95Fkn71.dll was not found. Reinstalling the application may fix this problem.
10/01/2015
Analyst Software
|
Initiate Transfer to Watson LIMS in SCIEX OS Software Prevents Analyst® Software from Launching When the feature Initiate Transfer to Watson LIMS is selected in SCIEX OS software, software users find that the Analyst® software installed on the same workstation will no longer launch. This is the expected behavior for Analyst software and depends on the configuration and the installation order of other SCIEX software that were installed on the same PC.
10/30/2020
SCIEX OS
|
Analyst Software
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Adding a Syringe Pump To a Hardware Profile in Analyst® Software Adding a syringe pump to a hardware profile in Analyst® software is necessary if the user needs to use the syringe pump to infuse sample during manual tuning. This article provides instructions on how to update a hardware profile to include a syringe pump.
11/04/2021
Analyst Software
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BioPharmaView™ software 2.x/3.0.x cannot open the data for subsequent samples if the data for the first sample is corrupted.
02/08/2019
Academia Omics
|
Pharma CRO
|
BioPharmaView Software
|
What Parameters in ProteoWizard Are Needed when Converting .wiff2 Files to mzXML Files? The parameter settings, including the PeakPicking value, that are used for converting .wiff2 files to mzXML or mzML files in ProteoWizard, are explained in more detail here.
12/16/2019
Academia Omics
|
Environmental Industrial
|
Food and Beverage
|
Forensics
|
Pharma CRO
|
Software
|
Incorrect Peak Area Sum when Using Sum Multiple Ions Feature in MultiQuant Software 3.0.1 The Sum Multiple Ion feature in MultiQuant™ 3.0.1 software can be used to sum the fragment ions of a precursor ion. Using this feature does not create a resulting sum that matches the result when Excel is used to calculate the sum of the XIC peak areas for the same fragment ions. The reasons are explained here.
03/22/2018
MultiQuant Software
|
Where Can I Find Instructions for the Protein Preparation Kit? Protein preparation instructions can be found on the SCIEX website at https://sciex.com/Documents/tech%20notes/Protein-Preparation-Kit-Protocol.pdf or https://sciex.com/products/standards-and-reagents/automated-protein-digestion-solution.
07/09/2018
Academia Omics
|
Pharma CRO
|
Standards and Reagents
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How to Set the Parameter Settings in Analyst® Software Back to Original Factory Settings The parameters settings in Analyst® software can be set back to the original, default factory settings by selecting the Parameter Settings option from the Tools menu and then using the Factory Settings button to reset the parameters of the selected scan type.
11/05/2020
Analyst Software
|
Where Is the Executable File for Excel Saved on My Computer? The executable file for Excel – Excel.exe – is located in the installation directory for the 64-bit version of Microsoft Office 365 at C:\Program Files\Microsoft Office\root\Office16.
12/02/2020
SCIEX OS
|
MultiQuant Software
|
Data File not in Expected Location in Analyst® Software Project Folder Ensure that the correct project folder is selected in Analyst® software prior to data acquisition. Data will be acquired to whichever folder is showing in the horizontal menu bar.
05/11/2018
Analyst Software
|
What are the Library Search Algorithms in SCIEX OS Software? When setting up a new processing method in SCIEX OS software's Analytics mode, there are three different library search algorithms that the user can select under the library search parameters dialogue: candidate, confirmation and smart confirmation search.
02/15/2019
SCIEX OS
|
How To Install Templates in Biologics Explorer Software This article describes how to install the template packages in Biologics Explorer software.
10/14/2022
Academia Omics
|
Pharma CRO
|
Software
|
Configuring a SCIEX X500 QTOF System after Downgrading SCIEX OS Software 2.0 to 1.7 After re-installing SCIEX OS software 1.7, stop the ClearCore2 service and then install the Microsoft C++ Redistributable package (vc_redis*.exe) from the install folder in the SCIEX OS 2.0 installation package. This will enable user to configure an SCIEX X500 QTOF System in the Devices workspace.
11/03/2021
SCIEX OS
|
Problem Uninstalling SCIEX OS Software Stems from Hidden SQL Driver While removing the SQL 2008 R2 Setup program during a SCIEX OS software de-installation, an error was received—indicating that the issue was due to the 2008 R2 RsFx driver, a "hidden" program that needs to be manually uninstalled using either the command prompt or regedit Windows functionalities.
10/29/2019
SCIEX OS
|
Resolving a Shimadzu LC Fatal Error: Could Not Activate Profile in Analyst® Software The LC/MS hardware profile containing a Shimadzu LC could not be activated in Analyst® software. Under the Configuration tab for the Shimadzu system controller (CBM), the serial port filed was selected and changed to TCP/IP. The IP address 192.168.200.99 was added.
05/17/2019
Analyst Software
|
What Is the Full Amino Acid Sequence of BETA-GALACTOSIDASE in the LC/MS Peptide Calibration Kit? The full amino acid sequence for beta-galactosidase is provided in the FASTA file format. The kit (part number 4465938) contains one vial of beta galactosidase digest (625 pmol/vial).
11/02/2017
Academia Omics
|
Pharma CRO
|
Chemical Standards Kit
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Report Template Editing Blocked after Upgrading SCIEX OS 1.6.1 Software from a Previous Version After updating SCIEX OS software from version 1.5 to 1.6.1, report template may be unable to be edited if Analyst® software is installed on the same PC. An error message appears in the Microsoft Word report template document: "Reporter Office addin. The provider with the name Quantitation already added to content control addin.Multiple custom type XML files found for the same provider." This article explains how to resolve this issue.
10/22/2019
SCIEX OS
|
Analyst® Report Template for LIS: Why Won't the LIS System Read Past the First Line of Data? If a CSV output file generated using the Analyst® software report template for LIS systems contains any cells with no data values, then the LIS system may not read past the empty cell. To ensure that the LIS reads the whole output file, each cell in the CSV file must contain a value of some kind.
12/14/2017
Analyst Software
|
Which License Supports LibraryView™ 1.3 Software Installed with SCIEX OS 1.4? LibraryView™ 1.3 software installed with SCIEX OS 1.4 requires a LibraryView 1.2 license.
08/31/2018
LibraryView Software
|
Sciex OS 1.5 Software Error: Processing Method Contains No Components or Is Incompatible When opening a processing method in Sciex OS 1.5 software, an error was received, indicating that the method contained no components or was incompatible. Removing the sub-folder (C:\SCIEX OS Data\<PROJECT NAME>\Quantitation Methods\<Sub-Folder>) resulted in normal software operation.
08/09/2019
SCIEX OS
|
Troubleshooting Peak Shape after Column Replacement After replacing the analytical column, the analyte's peak shape changed, leading to ion ratio failures. Replacing the guard column resolved the peak shape issues.
05/31/2018
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Analyst® TF Software Error: Instrument Optimization Parameters Are Not Available If the error message "Instrument optimization parameters are not available" appears when running Analyst® TF software, check the region and language settings and ensure that English (United States) is set as the default language in the Windows operating system settings.
12/13/2021
Analyst Software
|
What Fittings Are Needed To Add a Waters M-Class LC to My ZenoTOF 7600 System? This article explains which fittings are needed to add a Waters M-Class LC to a ZenoTOF 7600 system and includes part numbers and pictures of tubing and trap loop connections.
10/17/2022
QTOF Systems
|
Implementing Zeno SWATH Functionality on the ZenoTOF 7600 System To enable the Zeno SWATH pulsing function in the SCIEX OS software for the ZenoTOF 7600 system, upgrade the software to version 3.0 and then add the Zeno SWATH extension license for SCIEX OS software.
09/14/2022
|
How Does the Formula Finder Algorithm Work in Sciex OS Software? The Formula Finder algorithm in SCIEX OS software tries to predict the possible chemical formula based on the MS and MS/MS spectrum using the precursor ion's mass accuracy, isotopic pattern and MS/MS fragmentation pattern.
04/02/2019
SCIEX OS
|
Are There Differences in LIMS Column Headers between Analyst® and SCIEX OS Software? As users switch from Analyst® to SCIEX OS software, there may be concerns about column header or formatting differences between the two software versions when importing or exporting information using a LIMS. Although similar, there are format and column differences between the SCIEX OS and Analyst software systems, and SCIEX can provide examples for both formats.
05/18/2022
Academia Omics
|
Clinical
|
Environmental Industrial
|
Food and Beverage
|
Forensics
|
Pharma CRO
|
Software
|
How Do You Export a Library in LibraryView™ 1.0.1 Software? The export of a library from LibraryView™ 1.0.1 software is described here.
11/12/2018
Academia Omics
|
Pharma CRO
|
ProteinPilot Software
|
Sample VB Code for Hours of Instrument Usage Information from Analyst® Software Audit Trail Information about the hours of instrument usage can be obtained from the Analyst® software Audit Trail. Audit Trail data can be retrieved using IQuantAuditTrail interface methods NumEntries & GetEntry
05/31/2018
Analyst Software
|
Updating Quantitation Method Files in Analyst® and Multiquant™ Software with a New Analyte This article describes which method files need to be updated in Analyst® and MultiQuant™ software when new compounds are added to the method.
12/08/2017
Analyst Software
|
Can BioPharmaView™ and BPV Flex Software Coexist on the Same Computer? BioPharmaView™ Software 3.x and BioPharmaView (BPV) Flex Software 2.x are compatible and can be installed on the same computer.
10/21/2020
|
Error Code 50 Appears when Creating Reports in MultiQuant™ Software When creating reports in MultiQuant™ Software, an error appears, "Error code 50." This error is due to a corrupt file in the project folder, and a new project will need to be created.
12/04/2020
MultiQuant Software
|
ConfigUpdater.exe will not update instrument firmware. Issues with Windows Firewall preventing ConfigUpdater from updating instrument firmware via Ethernet connection.
07/08/2016
Software
|
What Information Is in the AnIML File Created by the Keystone™ Converter Software? AnIML, an open standard XML data format for storage and sharing of experimental data, is the file format that is created when a data file is converted by the Keystone™ converter software. This article details the information that is included in the converted AnIML file.
11/02/2021
Software
|
How to Create Custom Sample Trays for a CTC Autosampler How to configure a CTC autosampler to use custom dimensions for use with alternative plates or vial racks.
08/15/2018
|
Analyst Software Batch Editor Could not open the batch data DAB Sever Error When importing a Analyst batch from a file the import fails and the Error Could not open the batch data DAB Sever Error is displayed
09/04/2016
Analyst Software
|
Using the Same Peak Model for All Components in a Group with SCIEX OS AutoPeak Integration Algorithm In order to use the same peak model for all components in a group in SCIEX OS software, the user must enable the Peak Selection by Group and Process by Group settings in the Project Default Settings before creating the processing method.
02/15/2019
SCIEX OS
|
SCIEX OS 1.5 Installations on Windows 7 Require a TDC4 Driver Update SCIEX OS 1.5 installations on Windows 7 require a TDC4 driver update. Please navigate to the installation folder for Sciex OS and select the Drivers folder. Inside should be a program xTDC4_driver_v1.1.0.exe which will remove version 1.0.3 and install 1.1.0.
02/08/2019
SCIEX OS
|
BioPharmaView™ software 3.0.2 has improved its multiple attributes monitoring (MAM) workflow, and the software now includes a script, MAM-BPV to Analytics Converter, used to create a quantitative processing method for the Analytics mode of SCIEX OS software.
07/21/2021
Academia Omics
|
Pharma CRO
|
SCIEX OS
|
BioPharmaView Software
|
Generation of a New Root Directory for SCIEX OS Software Called C:\ClearCore Data Some users have reported the appearance of a new root directory created by SCIEX OS software that is not on the D: partition where the root directory (D:\SCIEX OS DATA) is typically located, but rather on the C: drive. This C: drive root directory has a different name (C: \Clearcore Data) and does not match the root directory that appears in the Configuration mode of SCIEX OS software in the Projects menu.
12/13/2021
SCIEX OS
|
Charge Heterogeneity Buffer Vial Plate Map for Tech Bulletin IB-17031A The plate map used in the SCIEX charge heterogeneity capillary zonal electrophoresis (CZE) assay will help guide users in setting up the method in the tech bulletin "Analysis of Monoclonal Antibody Charge Variants by Capillary Zone Electrophoresis" (Beckman Coulter IB-17031A).
11/15/2018
PA 800 Plus Pharmaceutical Analysis System
|
Clearing an Integrated Syringe Pump Error in Analyst® Software Different approaches are provided here to resolve an error message that appears in Analyst® software while using the integrated syringe in manual tune mode: "The current sample cannot be run because the syringe pump has reached the end of its travel. To solve this problem please refill the syringe, press "Clear Error" and resubmit the sample".
09/14/2022
Analyst Software
|
Plotting 32Karat Software Data Files that Have Been Exported as ASCII Files into Excel To plot 32Karat software data into a graph/electropherogram format, open the ASCII file in Excel and then format the data as described.
04/22/2019
PA 800 Plus Pharmaceutical Analysis System
|
What Is a Fraglet.exe Error when Running ProteinPilot™ Software 5.0? A "Fraglet-exe-Error" can have many causes within the ProteinPilot™ software. In some cases, this error is caused when installing ProteinPilot on an incompatible operating system.
07/14/2017
Academia Omics
|
Pharma CRO
|
ProteinPilot Software
|
SCIEX OS Software: Internal Standard Data in Report Does Not Match the Results Table If a report generated from SCIEX OS software using a template and a query contains information about internal standard samples, the internal standard information showing in the results table does not appear correctly in the report. To resolve this issue, all internal standard samples must be listed at the bottom of the SCIEX OS software processing method in the components section.
11/09/2019
SCIEX OS
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What Do SCIEX Validation Services Include? SCIEX qualification services include testing and documentation that demonstrates that the instrument is operating correctly and includes objective evidence showing what was tested, the specification for each test, and the results.
02/11/2022
Software
|
Turning the Checksum Option On or Off in Analyst® Software In order to turn the checksum option on in Analyst® software, select the View menu and then choose Audit Trail Manager.
10/29/2020
Analyst Software
|
How to Remove the Extra Characters from an Analyte Name in a Report To report the analyte name in a report without additional characters showing after the name, use the TRIM and LEN functions in the expression written in the Math Field Type tag in the report template.
11/05/2020
SCIEX OS
|
MultiQuant Software
|
Adding Custom Columns to a SCIEX OS Software Report Template In SCIEX OS software, a custom column added to a results table can be included in a report template with a custom tag.
10/30/2020
SCIEX OS
|
Why Do the Results for Some Analytes Shift to a New Column in a CSV Report? When reporting results table values to a comma-separated values (CSV) report, for some analytes, the reported information is shifted from the correct column to one column over to the left. This column-shifting issue is observed when an analyte name contains a comma.
11/10/2020
SCIEX OS
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Analyst Software
|
MultiQuant Software
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SCIEX Trial License Key Not Received The email address associated with your Sciex login must be verified when you request a trial license, otherwise you will not receive your trial license key by email.
07/03/2018
Software
|
Printing an Unsecured Report as a PDF with MultQuant™ or SCIEX OS Software Reports printed as PDF files from either SCIEX OS or MultiQuant™ software are always secure because they are printed using pdfFactory. A workaround must be used to print unsecured PDF reports.
05/13/2020
SCIEX OS
|
MultiQuant Software
|
Create Acquisition Method with Agilent HPLC in Analyst® Software Walk Through of Analyst acquisition method (.dam) creation when a Agilent HPLC is employed.
02/05/2016
Mass Spectrometers
|
Analyst Software
|
What Is the Format of a LIMS Template? A LIMS template is used to transfer data from a MultiQuant™ software results table to a LIMS system. The LIMS template is a comma delimited file with the fields to be output listed across the top of the report. Each field in the template should be separated by a comma.
10/22/2019
Software
|
Archiving and Purging MALDI TOF/TOF™ Data and Creating Database Backups Described herein is a general procedure on how to archive/purge data from a MALDI TOF/TOF™ system, as well as how to back up data.
05/31/2018
Academia Omics
|
Pharma CRO
|
No Help Topics Appear in the SCIEX OS Software Help System Selecting the question mark in the upper right hand corner of SCIEX OS software launches the SCIEX OS Help System screen. If no information appears for a selected topic, the SCIEX OS Help.chm file located in the C:\Program Files\SCIEX\SCIEX OS\Documentation folder needs to be unblocked.
11/09/2019
SCIEX OS
|
Where Can the Software for StatusScope® Remote Monitoring Service Be Accessed? To obtain access to the software download for StatusScope® Remote Monitoring service, users who are under warranty or who have purchased the service can navigate to statusscope.absciex.com and select the link to the software download.
09/29/2019
Mass Spectrometers
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Is the SelexION® Device Compatible for Acquisition with SCIEX OS Software? No, the SelexION® device is not yet supported in SCIEX OS software.
05/18/2022
Pharma CRO
|
Software
|
What is the Difference Between an EMC and an EMS Scan on a QTRAP® System? The EMS and EMC scans are two different scan types that can be run on a QTRAP® system, making use of the linear ion trap (LIT) functionality. The EMS or enhanced mass scan is a full mass range MS scan in the LIT. The EMC or enhanced multiple charge scan is carried out in the LIT, where high charge state ions are selectively trapped and scanned.
11/04/2021
QTRAP Systems
|
Where Can I Download Skyline Software ? This article includes the link to a free download of Skyline software.
11/09/2017
Academia Omics
|
Pharma CRO
|
Skyline Software
|
Remote Data Access Software Error on MALDI TOF/TOF™ instruments When setting up ProteinPilot™ Software or the imaging acquisition software for the MALDI TOF/TOF™ Systems, a RDA (Remote Data Access) software error message is received: "TOF/TOF Imaging Acquisition Software. The client components used to communicate with the instrument are newer than those found on the instrument. Please update the Remote Data Access service on the instrument."
11/09/2020
Academia Omics
|
Pharma CRO
|
Unable to See Chromatograms when a MultiQuant™ Software Report is Printed If the Peak Fill option is set to "Do Not Fill Peaks" in MultiQuant software, chromatograms will be faded out when output to a report and sometimes appear as not legible.
11/03/2021
MultiQuant Software
|
Updating the Sample Information Column in MultiQuant™ Software Results Table Updating the sample name column in MultiQuant™ software will fail and result in an error message if invalid characters are used in the added text. The Sample Name and Sample ID columns cannot contain the following characters: \ / : * ? " < > | = or . .
12/28/2018
MultiQuant Software
|
Turbo V™ Ion Source Heater Replacement How to replace the ion source heaters in the Turbo V Ion Source
02/05/2016
QTRAP Systems
|
Triple Quad Systems
|
TripleTOF® System Vacuum Interface Routine Cleaning How to clean the vacuum interface of the TripleTOF instruments
02/05/2016
Academia Omics
|
Environmental Industrial
|
Food and Beverage
|
Forensics
|
Pharma CRO
|
Setting Up a New Project in SCIEX OS Software Projects can be created in the Status panel by selecting the white plus sign in a circle icon next to the projects drop down menu. Selecting the button will bring up the New Project screen where the name of the New Project will be entered. Projects can also be created in the Configuration module by selecting the Projects tab.
11/04/2021
SCIEX OS
|
Can Data Files Be Renamed after Acquisition Is Complete? It's possible to change the name of a raw data file after it has been acquired in Analyst® or SCIEX OS software. Both the .wiff and .wiff.scan files would have to be named in the exact same manner or they may become corrupted.
11/04/2021
Analyst Software
|
Importing *.xlsx Files to Build Batches in Analyst® Software Importing *.xlsx files to build batches in Analyst® software requires Microsoft Office 32-bit to be installed, although its not recommended to use the 32-bit version of Office on a 64-bit Win 7 operating system. SCIEX recommends that the following file formats be used instead: .xls, .csv and .txt.
12/13/2017
Software
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Can I use the Proteinpilot SW with 4700 data Can I use the Proteinpilot SW with 4700 data
10/07/2016
Academia Omics
|
ProteinPilot Software
|
Activating Analyst TF 1.7.1 Hardware Profile in Sim Mode When running Analyst TF 1.7.1 in sim mode on a processing workstation, an additional driver, the Chronologic driver, must be downloaded and installed.
11/01/2018
Analyst Software
|
Where are the Cliquid Software Report Templates Located? The Cliquid® software report templates are saved in the folder D:\Analyst Data\Projects\Cliquid\Templates\ReportTemplates.
10/16/2019
Cliquid Software
|
Troubleshooting the ZenoTOF 7600 System: In-Run Calibration Failures If a calibration failure occurs while acquiring data on the ZenoTOF 7600 system, then certain measures can be followed to mitigate this issue. The troubleshooting guide provided in this article is a step-by-step path for resolving any problems with in-run calibrations. To begin troubleshooting in-run calibration failures, users should open the calibration report in the Analytics workspace of SCIEX OS software to identify the reasons behind the failure.
12/15/2022
QTOF Systems
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Bio Tool Kit Software License iNeeded for SCIEX OS 1.x and PeakView Software. The Bio Tool Kit software can be activated within PeakView 2.x and SCIEX OS 1.x software but a separate software license is needed.
02/08/2019
Academia Omics
|
Food and Beverage
|
Pharma CRO
|
Bio Tool Kit Software
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Sciex OS Software Report Error: An Item with the Same Key Has Already Been Added An error was received while using Sciex OS software to generate a report: "Error during Report generation. An item with the same key has already been added." No report was generated. To resolve this issue, open the report template and see if a query file is linked through the Meta Field tag. If a query is linked, open the query and evaluate it for any duplicate column names. Delete any duplicate columns from the input sheet.
03/20/2020
SCIEX OS
|
Unhandled exception has occurred Waters Acquity Method Editor v1.4 & 1.5 When saving or opening a method with the Waters Acquity Method Editor an unhandled exception occurs System.NullReferenceException Object reference not set to an instance of an object
06/02/2016
Analyst Software
|
SCIEX OS Software: Unable to Upload Exported Text File to Watson LIMS In SCIEX OS software 2.1.6, if the internal standards appear in any location in the results table, instead of being grouped together at the bottom of the analyte list, and are distributed throughout the processing method, then the exported results text file cannot be uploaded to Watson LIMS.
11/04/2021
SCIEX OS
|
Peak Labels from Analyst® Report Are Missing in MultiQuant™ Software Report To add in the labels to reports generated in MultiQuant™ software, the tag for Peak Review has to be edited to show the Analyte_Peak_Name in the Label field.
10/19/2018
MultiQuant Software
|
PA800 How To - Installing the LIF Detector Installing the LIF Detector
05/02/2017
Pharma CRO
|
PA 800 Plus Pharmaceutical Analysis System
|
Polarity Switching Is Not Supported in Analyst® Software Versions below 1.6 To run sMRM methods with polarity switching, Analyst® software 1.6 or greater must be used.
09/26/2017
Analyst Software
|
Reasons for Data File Processing Failure with the Data Converter Version 1.3 Beta What are the potential issues listed which can cause the SCIEX MS data converter version 1.3 beta to not work correctly?
11/22/2017
Academia Omics
|
Pharma CRO
|
Software
|
How To Create Sub-project Folders in SCIEX OS Software Within projects, data can be further organized in sub-folders in SCIEX OS software. This article explains how to create a sub-project using the Add Data Sub-Folders dialog in the Configuration workspace.
11/04/2021
SCIEX OS
|
Where are the SCIEX OS Software Report Templates Located on My PC? If a report template needs to be opened for editing or if a new custom template needs to be added to the template list in SCIEX OS software, then navigate to C:\ProgramData\SCIEX\Analytics\Reporter to locate or add a template.
11/08/2019
SCIEX OS
|
Compound Parameters Not Loading in Analyze Mode in DiscoveryQuant™ 3.0.1 Software Compound parameters could not be uploaded in Analyze mode in DiscoveryQuant™ 3.0.1 software after switching from a local database to SQL database due to issues with the database selected as the review database.
05/14/2019
Pharma CRO
|
DiscoveryQuant Software
|
PA800 How To - Cartridge Removal Rebuild Reinstallation Procedure for Cartridge Removal Rebuild Reinstallation on PA800 System
05/02/2017
Pharma CRO
|
PA 800 Plus Pharmaceutical Analysis System
|
Where Can I Find My Hardware Profile in SCIEX OS Software? The hardware profiles for instruments supported by SCIEX OS software are stored in a file called HardwareProfile.hwp that is located in the following directory: C:\ProgramData\SCIEX\Clearcore2.Acquisition.
10/30/2020
SCIEX OS
|
Windows 7 and 10 Operating Systems Are Compatible with Analyst® Administrator Console 3.0 Windows 7 and 10 operating systems are compatible with Analyst® Administrator Console 3.0 software.
04/16/2020
Analyst Software
|
Adding Custom Columns to a Results Table in Analyst™ Software To add custom columns to a results table in Analyst™ software, right click within an open results table and select the option Add Custom Column.
10/30/2020
Analyst Software
|
How Can I Sum Vitamin D2 and D3 in SCIEX OS Software? To add the calculated concentrations for vitamin D2 and D3 together and calculate the total vitamin D, a custom calculation in SCIEX OS software will need to be created in the processing method in the Analytics mode. The calculation will add custom column named Total VitD to the results table and provide a sum of the values for the calculated concentrations for vitamin D2 and D3.
12/05/2021
SCIEX OS
|
How to wire SCIEX AUXIO cable for use with a Waters Acquity HPLC System Diagram of how to wire AUXIO connections for the Acquity HPLC including the Stop Flow on instrument error
06/02/2016
Mass Spectrometers
|
Network Acquisition and Processing of Analyst® Software Data Files and Time Stamps When data files acquired with Analyst® software are saved to a network server, does the time stamp on the data come from the local machine or the network server? After processing data in the Analyst project folder residing on the network server, the results files were also saved on the network server. Does the data time stamp come from the local machine or the network server?
05/15/2018
Analyst Software
|
Can I add a Compound to My Library with MasterView™ instead of LibraryView™ Software? LibraryView™ software, but not MasterView™ software, must be used to add a compound to an existing library. You can use MasterView software to import other libraries or a new library, but not a new compound from a newly acquired MS/MS spectrum.
09/26/2017
MasterView Software
|
To ensure that only the positive hits appear in a report generated using the Positive Hits template rather than all visible results in a results table, the results table itself first needs to be filtered to show only positives prior to running the report.
10/16/2019
SCIEX OS
|
Does BPV Flex Software Support Multiple Period Experiments? BPV Flex can only open the first period of multiple period experiment runs.
09/27/2019
Pharma CRO
|
BioPharmaView Software
|
Verifying if .NET Framework 3.5.1 Is Installed on a Windows 7 Operating System To verify if .NET Framework 3.5.1 is installed on a PC running a Windows 7 operating system, the .NET Framework Verification Tool may need to be deownprogram in the link provided.
05/24/2019
Software
|
Why Is No Data Acquired in EAD Fragmentation Mode on a ZenoTOF 7600 System? If EAD fragmentation is used in an acquisition method on a ZenoTOF 7600 system, then the accumulation time must be at least three times the reaction time. If it is not, then no data will be acquired. To resolve the issue, increase the accumulation time in the method in SCIEX OS software.
11/03/2021
SCIEX OS
|
Reporter gives an error on Analyst 1.6.x workstation Unexpected error has occurred Reporter gives an error on Analyst 1.6.x workstation Unexpected error has occurred
07/08/2016
Analyst Software
|
Why Can't I Open Analyst® Software when My Security Role Is Set to Supervisor? If a user has the security role of supervisor in Analyst® software, then he/she can override a screen lock or logout of the software--but only if the Analyst security configuration is set to Mixed Mode.
12/22/2017
Analyst Software
|
Are the Ion Sources Interchangeable Between the QTRAP® and TripleQuad™ 6500+ and 7500 Systems? The ion sources for the SCIEX QTRAP® and TripleQuad™ 6500+ and 7500 LC-MS/MS Systems are not interchangeable. The OptiFlow® Pro Ion Source cannot be used on the QTRAP or TripleQuad 6500+ Systems. Likewise, the IonDrive™ Turbo V, Turbo V™, and OptiFlow Ion Sources cannot be used with the QTRAP and TripleQuad 7500 Systems.
11/06/2020
QTRAP Systems
|
Triple Quad Systems
|
Which Calibration Standards Can Be Used for Intact Protein Analysis on TripleTOF® and X500 Systemss? An APCI calibrant solution for the SCIEX X500B System and a mAb standard from Waters were compared. Results show that the mass to charge ratio for the calibrant solutions remain constant regardless of the charge state. Secondly, for readings over 500 m/z, the calibration is highly linear for the X500B system.
12/14/2017
Academia Omics
|
Pharma CRO
|
QTOF Systems
|
Recommendations for Computer Maintenance for Analyst® Software What types of computer maintenance can be done to ensure that Analyst® software runs smoothly?
05/26/2017
Analyst Software
|
Converting MultiQuant™ Software Qmethods to Sciex OS Software Qmethods This article contains a step-by-step guide for converting a MultiQuant™ 3.0.3 software quantitation method (.qmethod) file to a Sciex OS 1.5 software quantitation method file (.qmethod).
06/26/2019
SCIEX OS
|
MultiQuant Software
|
Compounds Need to be Assigned to a Library to be Recognized in Cliquid® Software A MS/MS spectra was added to a compound record in LibraryView™ software, but subsequent confirmation runs in Cliquid® software failed. The root cause of the issue was the compound in the LibraryView software database was not associated with any named library.
12/15/2021
Cliquid Software
|
LibraryView Software
|
Is There a Password Character Limit for Accessing Analyst® Software in Mixed Mode? Passwords used to access Analyst® software in mixed mode are capped at 13 characters. If your internal IT policy for the Windows password specifies more characters, this longer password requirement may lock the user out of Analyst software in mixed mode.
10/30/2020
Analyst Software
|
Power cycling the PC, HPLC, and MS to solve communication problems A power cycle can be performed on LCMS components to solve communication problems.
03/20/2017
Mass Spectrometers
|
Transferring Acquisition Methods Between Analyst® Software and Analyst MD Software Is it possible to move an acquisition method that was created in Analyst® software to Analyst MD software?
08/10/2022
Software
|
Why Does the SCIEX OS Software 2.1.6 Installer Disable the System Restore Task? The SCIEX OS software 2.1.6 installer disables the System Restore task for better performance of the application.
11/03/2021
Software
|
Do I Have the Central Administrator Console (CAC) Server Installed for SCIEX OS Software on My PC? Users can determine if the Central Administrator Console (CAC) server is installed on their PC by checking if the splash screen at startup displays the name SCIEX OS Central Administrator Console or by checking the About menu in the Configuration mode of the software. Also, one of the four workspace tiles on the home screen says Central Administration once the software loads.
09/30/2022
Pharma CRO
|
SCIEX OS
|
Analyst® Software: Where Are the Library Search Parameters Set? In Analyst® software, the library search parameters such as maximum number of hits, minimum purity, hit, etc. are set in the config files that are saved under C:\Program Files (x86)\AB SCIEX\AnalystReporter\Resources\AlgorithmConfigFiles.
11/04/2021
Analyst Software
|
Troubleshooting Common LC Issues on SCIEX Triple Quad™ and QTRAP® Systems Pressure issues, shifting retention times, and no peaks are common issues when running LC-MS methods. The guides linked tp this article provide step-by-step instructions to troubleshoot these common issues.
01/17/2023
QTRAP Systems
|
Triple Quad Systems
|
How to Export the Settings for the Central Administration Console (CAC) Software Users can export the security settings from a Central Administration Console (CAC) server used to manage SCIEX OS software users and projects. The settings are exported as an ECAC file and can be imported into another CAC server installation to transfer the security settings.
09/16/2022
Pharma CRO
|
SCIEX OS
|
Where is the SCIEX OS Software Security Database Found? The SCIEX OS software security database files are located at C:\ProgramData\SCIEX\Clearcore2.Acquisition, and the file is called Security.data.
10/30/2020
SCIEX OS
|
Can SCIEX OS and MasterView™ Software Be Installed on the Same Computer? SCIEX OS and MasterView™ software are not compatible, and they cannot coexist on the same computer.
09/24/2019
SCIEX OS
|
MasterView Software
|
MultiQuant™ Software Would Not Launch after License Installation MultiQuant™ software may not launch after installation, and a -1 license installation error may appear. To resolve this issue, the user needs to be logged into Windows as an administrator and have full access to the program files on the C: drive.
10/17/2017
Software
|
Using Ammonium Fluoride (AMF) in an HPLC Solvent Ammonium fluoride can be used in LC/MS applications as a mobile phase additive. It is recommended that only small concentrations as possible be used (around 0.2 mM).
07/03/2018
Mass Spectrometers
|
Filtering Library Results for Compounds in MetabolitePilot™ Software Using the blue funnel icon in MetabolitePilot™ software in the top right of the Result Pane will help narrow the search results provided when evaluating information-dependent acquisition (IDA) data for possible compounds that correspond to potential metabolite.
12/28/2018
LibraryView Software
|
ProteinPilot gives the error fraglet.exe not wellformed invalid token at line 1 and position 33112not wellformed invalid token at line 3 and position 71
10/07/2016
Academia Omics
|
ProteinPilot Software
|
Will SCIEX Have a Windows 10 Compatible Analyst® and Mutiquant™ Software Version? Analyst 1.7 software and Multiquant 3.0.3 software are now available, and both of these versions are Windows 10 compatible.
12/20/2017
Software
|
Possible Non-Numerical Outcomes for MultiQuant™ Software Results Tables Instead of a number, sometimes MultiQuant™ software returns a non-numerical result in the results table.
10/18/2018
MultiQuant Software
|
When creating excel reports using Chemoview 2.0.2 the report creation will fail and the message Programmatic Access to Visual Basic Project is not trusted will be displayed in the report preview.
06/02/2016
Clinical
|
ChemoView Software
|
Create Acquisition Method with Shimadzu HPLC in Analyst® Software Walk through of creating an Analyst acquisition method (.dam) when a Shimadzu HPLC is employed.
02/05/2016
Mass Spectrometers
|
Analyst Software
|
Controlled Ways to Output Data from SCIEX OS Software The controlled ways to output data from the SCIEX OS software Analytics workspace include 1) exporting a results table; 2) Transferring the results table data to a LIMS; and 3) Creating a report though the Reporting tab option Create Report and Save Results Table.
11/05/2020
SCIEX OS
|
Installing and Activating a New License for a Computer not Connected to the Internet If a software license needs to be installed on a computer that is not connected to the internet, look up the computer IDs for that computer, copy them, and then activate the license on an internet-connected workstation.
09/11/2017
Software
|
Unable to Create Reports in MultiQuant™ Software The Create Report option in MultiQuant™ software is not showing in the File menu because the incorrect version of Microsoft Office is installed.
05/17/2017
MultiQuant Software
|
Longer Power Cycle May Help To Resume Instrument Connectivity after Power Failure Even after resetting the mass spectrometer (by following the power-cycling procedure), the instrument would not come back online after a power failure. On some occasions, the mass spectrometer must be completely powered down for at least 1 min in order for the circuits to discharge and fully release any faulty information.
10/01/2019
Mass Spectrometers
|
Setting Up the LC Pressure Trace Monitoring for an Acquisition Method in Analyst® Software Setting up the LC pump pressure trace and column oven temperature trace monitoring supported by Analyst® software 1.7.3 is explained here. The resulting pressure traces can be stored in the data file for each sample.
03/03/2023
Software
|
When Do I Click the Confirm Button in SCIEX OS Software during Watson LIMS Data Transfer? When transferring data to Watson LIMS from SCIEX OS software, the user must wait for the transfer to complete successfully before clicking Confirm in SCIEX OS software. It the user clicks Confirm before the transfer is complete, then the transfer status will show as failed.
11/03/2021
SCIEX OS
|
Instrument readbacks log from Analyst Where to locate the instrument readbacks log from Analyst
03/16/2023
|
PA800 How To - Changing a Detector Changing a Detector
05/02/2017
Pharma CRO
|
PA 800 Plus Pharmaceutical Analysis System
|
SCIEX 5500&6500 Systems Pump Oil Change How to change the oil in the pumps for the 5500 and 6500 series instruments
02/05/2016
QTRAP 5500
|
QTRAP 6500
|
Triple Quad 5500
|
Triple Quad 6500
|
Recalibrating TOF MS or TOF MS/MS Spectra in SCIEX OS Software To recalibrate a TOF MS or TOF MS/MS spectrum or recalibrate samples in SCIEX OS software, open the data file in Explore mode, select process, and then select Recalibrate Spectrum or Recalibrate Sample.
03/21/2019
SCIEX OS
|
Two New Tiles in the OneOmics™ Suite Support Data Processing with DIA-NN Software The two new software tiles in the OneOmics™ suite are the Ion Library app and the DIA Results app. These apps are used to process data-independent acquisition (DIA) data acquired by the ZenoTOF 7600 system, along with the DIA-NN software module that is embedded in the OneOmics suite.
03/03/2023
Academia Omics
|
Software
|
Adding a Flag or a Custom Flag Created in SCIEX OS Software to a Report After creating a new results table in SCIEX OS software, add the Outlier Reasons column in the quantitation method to the Input tab of a query. Then, in the AnalystCalculations tab of the query, use the search function to find the flag of interest. Have the Outlier Reasons column added to the query's Output tab, and then link the Outlier Reasons column to the report template using a custom tag.
11/05/2020
SCIEX OS
|
How to print from XIC Manager in PeakView Description of the methods which can be employed to print from XIC Manager.
09/04/2016
Environmental Industrial
|
Food and Beverage
|
Forensics
|
Software
|
How to Export the Peak List in SCIEX OS Software SCIEX OS software users can save the peak list for the currently active spectrum or chromatogram to a tab-delimited text file. This file contains information such as the centroid X-value (mass or time), peak area, height, etc.
11/04/2021
SCIEX OS
|
Upgrading SCIEX Software Licenses How to upgrade self-upgrade registered software licenses
01/27/2020
Software
|
Which Folders Should Be Backed Up Before Upgrading the SCIEX OS Software? Prior to upgrading or removing SCIEX OS software, back up the SCIEX OS Data folder and the SCIEX folder in the Program Data folder.
03/20/2020
SCIEX OS
|
LC Pumps Continue to Run after a Batch Ends in Analyst 1.6.3 If a batch completes, but the LC pumps never turn off, the Max Idle Time may need to be adjusted in Queue Options.
04/27/2017
Analyst Software
|
Can Results Tables Created in MultiQuant™ Software Be Opened in SCIEX OS Software? It is not possible to open a results table (.qsession file) that was generated in MultiQuant™ software in SCIEX OS software.
08/31/2022
Software
|
Configuring Analyst® Software for Email Notification of Audit Trail Events Users can configure the Analyst® software to send an email message if there are three log on errors within one day. This email notification is available only if the workstation is in Integrated Mode or Mixed Mode.
12/21/2017
Analyst Software
|
How To Configure the OptiFlow® Turbo V Ion Source with the Microflow Probe for Nanoflow Rates The OptiFlow® Turbo V ion source with the microflow probe can be configured for nanoflow rates, allowing for the continued use of the calibrant delivery system (CDS) for automated calibration.
03/03/2023
Academia Omics
|
Exporting PDA data from 32Karat into ASCII or AIA (.CDF) files Procedure to export CE data files from the 32Karat software.
04/05/2019
PA 800 Plus Pharmaceutical Analysis System
|
How Are Graph Axis Setting Changed in Analyst® Software? To change the x- and y- axis settings for a chromatogram in Analyst® software, navigate to the Tools menu, select Settings, and then the Appearance Options menu. The x- and y-axis options are in the Other Graph Options tab.
05/14/2018
Analyst Software
|
Which Glycan Notation Is Used in the BioPharmaView™ Software? The glycan notation used in BioPharmaView™ Software is the Oxford style.
11/10/2020
Academia Omics
|
Pharma CRO
|
BioPharmaView Software
|
Setting Up a Scheduled Ionization Method in Analyst 1.7 Software The scheduled ionization feature can be used to reduce the mass spectrometer downtime by decreasing the risk of contamination. To set up a scheduled ionization method in Analyst® 1.7 software, follow the instructions below.
05/01/2018
Analyst Software
|
If actual concentration values for standards are omitted from a MultiQuant™ or Analyst® software results table, then the data points for standard concentration versus peak area will all be aligned with zero on the x-axis in the calibration curve, looking nothing like the expected diagonal line. Adding the actual concentration information for the standards spreads the points across the x-axis and restores the expected diagonal linear regression line.
10/17/2019
Analyst Software
|
MultiQuant Software
|
Adding Custom Columns In a Batch in Analyst® Software To add a custom column(s) to a batch in Analyst® software, right click within the batch table on the Sample tab, and select Add Custom Column.
11/07/2019
Analyst Software
|
When using the Reporter Template Suite Software with MultiQuant™, Analyst® or SCIEX OS software, the report output may indicate "no data" in the sample comment column if there is no text in the corresponding column in the results table. To eliminate "no data" as a response in the report, try using the following IF/ELSE statement: IF EMPTY($Sample_Comment) (Text Field: none) ELSE (Text Field: Sample Comment)
11/14/2021
SCIEX OS
|
Analyst Software
|
MultiQuant Software
|
How to Update or Link a Query File to a Report Template If the name of a query is ever changed or updated or if a new query needs to be attached to a report template, the query must be relinked to the template used for reports created in MultiQuant™, Analyst® or SCIEX OS software.
10/23/2019
SCIEX OS
|
Analyst Software
|
MultiQuant Software
|
Opening SCIEX OS Results Tables Containing UV and MS Data To open a SCIEX OS results table created using a data file (.wiff2) with both UV and MS data, both data types must be selected for processing when creating the quantitation method in Sciex OS. Otherwise, an error message is received "Error. Cannot be empty, Parameter name: experiments" when opening Sciex OS results tables after they are created.
12/13/2017
SCIEX OS
|
Description of the Cause of Invalid transition list format error
10/07/2016
Academia Omics
|
Analyst Software
|
Skyline Software
|
Returning the Results Table Settings to Defaults in Analyst® Software If custom settings are applied to a results table in Analyst® software, they can be reversed by selecting the default settings option. To do so, right click within the results table to generate a secondary menu. Select the Table Settings option and then select Default.
05/03/2022
Analyst Software
|
Compatibility of Standard MutliQuant™ Software Files with MultiQuant MD Software This article describes the compatibility of standard, non-GLP MutliQuant™ software files with MultiQuant MD software.
12/28/2018
MultiQuant Software
|
Downloading Software from the SCIEX Website Requires the Most Current Browser To successfully download a trial license or software from the SCIEX website, your browser needs to be up-to-date.
05/11/2018
Software
|
Reporter 3.0 or 3.2 Cannot see tags for formatting. Word does not show the tags content controls used for creating reports.
07/08/2016
Analyst Software
|
Exporting Mascot Searches from QTOF and MALDI TOF/TOF™ Systems for PRIDE Submission Mascot searches can be exported from the Mascot server; but the data needs to be converted to the mzIdentML file format and then submitted to PRIDE. This article only describes how to export a Mascot search.
05/06/2022
Academia Omics
|
Considerations when Installing or Upgrading to Sciex OS 1.2 When upgrading to Sciex OS 1.2 from version 1.0, the software for Sciex OS 1.0 must be uninstalled prior to installing Sciex OS 1.2. LibraryView Framework version 1.1 must be removed as well. Certain companion software must be removed as well, and installed again after Sciex OS 1.2 is installed.
04/25/2017
Software
|
Creating a ProteinPilot Software Winner Proteins Results List as FASTA File This article describes the steps for creating a FASTA file from a ProteinPilot™ software report of winner proteins.
11/06/2020
Academia Omics
|
ProteinPilot Software
|
LibraryView 1.0 Error 21467259 failed to create SQL database Unknown Error When installing LibraryView 1.0 the following error message is shown. Error 21467259 failed to create SQL database LibraryView error detail Unknown Error.
10/01/2015
Environmental Industrial
|
Food and Beverage
|
Forensics
|
LibraryView Software
|
Changing the Number of Decimals Displayed in Analyst® Software Calibration and Metric Plots This is a set of instructions for changing the number of decimals displayed in Analyst® software quantitation metric plots and calibration curves. The default number of decimals leaves the significance so low that you can not reproduce the results shown in the results table. A warning is given to let customers know that Regedit is a dangerous utility.
02/28/2019
Academia Omics
|
Clinical
|
Environmental Industrial
|
Food and Beverage
|
Forensics
|
Pharma CRO
|
Software
|
Where Can I Download Skyline Unplugged for a Windows 10 64-bit PC? Link is provided and installations instructions are described
11/02/2021
Academia Omics
|
Pharma CRO
|
Skyline Software
|
Is a Special Administrator Account Required for the Central Administrator Console (CAC) Software? A special administrator account is not required for the Central Administrator Console (CAC) software. The CAC server uses the standard SCIEX OS software roles to manage CAC administration permissions.
09/20/2022
Pharma CRO
|
SCIEX OS
|
Unspecified error when using Quantitate in Analyst Software This article describes how to resolve the Unspecified error message encountered when trying to quantitate a new batch with Analyst Software
10/01/2015
Analyst Software
|
How to Sum the Concentrations of Isomers in SCIEX OS Software To add the concentrations of different isomers together when processing data in SCIEX OS Software, open a processing method in the Analytics mode of the software. Select the Calculated Columns tab in the processing method and then select Add Formula to create a custom calculation for adding the isomers.
12/02/2020
SCIEX OS
|
Resolving the Error "Unexpected Error Has Occurred" when opening Reporter In Analyst® Software When opening Reporter in Analyst® software, an error message appears reading "Unexpected error has occurred."
09/14/2022
Analyst Software
|
Injection Error Dectected after Sample Start: Shimadzu LC Controller Device Fault If an injection error is detected after starting samples in the Analyst® software queue, and everything else seems fine with the LCMS system, check that the Shimadzu autosampler rack is seated correctly in the autosampler housing.
12/14/2017
Analyst Software
|
How to Apply Regional Settings in SCIEX OS Software This article describes how to have the Windows regional settings (language, time/date formatting and regional preferences) match the formatting in SCIEX OS software.
11/04/2021
SCIEX OS
|
Status Display Issue for ExionLC 2.0 Systems with UV/Vis Detectors in Analyst® Software If an Exion LC 2.0 system contains a DAD or multiwavelength detector, then after the LC system and mass spectrometer go to Standby state, the Analyst® software status icon for the ExionLC 2.0 system turns yellow, but the LC system state is shown as Wait.
11/03/2021
Analyst Software
|
MetabolitePilot™ 1.5 Software Upgrade License Requires Older 1.0 License as Base When MetabolitePilot™ 1.5 software is launched, an error is received after reinstalling the software indicating that a demo version of the software license has expired. If the license being installed is a MetabolitePilot 1.5 upgrade license, it will always need to be installed alongside the original MetabolitePilot 1.0 license.
12/28/2018
MetabolitePilot Software
|
How to use Mixed Mode in SCIEX OS Explains the different Security Modes and how to use them. More details can be found in SCIEX OS Laboratory Directors Guide
02/07/2023
SCIEX OS
|
Scheduled MRM™ Data with Polarity Switching Not Opening in MultiQuant™ Software Scheduled MRM™ methods with polarity switching must use the same sMRM mode--either basic or advanced--but not both in the same Analyst® software acquisition method.
10/04/2017
MultiQuant Software
|
Do I Need To Revalidate My Software Workflow after Upgrading from Analyst® to SCIEX OS Software? Yes, the software workflow will need to be revalidated after upgrading from Analyst® to SCIEX OS software. SCIEX OS software is a completely different software platform than Analyst software, and because even minor changes require revalidation, the switch from Analyst to SCIEX OS software will also require a revalidation.
05/18/2022
Pharma CRO
|
Software
|
How Do I Convert Acquisition Methods Created in Analyst® Software for Use in SCIEX OS Software? Users can convert existing acquisition methods created in Analyst® software for use in SCIEX OS software by using the Convert File option in the Open menu in the MS Method tile. Only the MS portion of the method will be converted; there is no conversion function for the LC portion of the method.
08/08/2022
Mass Spectrometers
|
Software
|
How Do I Display the Calibration Peak List in Analyst® Software? This article describes how to apply the appropriate calibration peak list reference table during a tuning procedure in Analyst® software.
11/02/2021
Analyst Software
|
Is Installing a SCIEX Software Hotfix on an Unsupported Instrument Problematic? There are no negative effects caused to software or instruments by installing SCIEX software hotfixes on an instrument model not expressly covered by the hotfix (as indicated in the release notes).
11/03/2021
Analyst Software
|
MultiQuant™ Software Cannot Launch with an sMRM Extension License Only Two licenses need to be installed when using an sMRM extension license: One must be the MultiQuant™ software basic license, and the other is the sMRM extension license.
11/22/2017
MultiQuant Software
|
Clearing a Manual Tune Error Message in Analyst® Software If the syringe runs dry while doing direct infusion, a manual tune error may disrupt compound optimization in Analyst® software manual tune mode, requiring an LC/MS system reset.
12/21/2017
Analyst Software
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Exporting ProteinPilot™ Software Data to PRIDE (PRoteomics IDEntifications) Exporting ProteinPilot™ software data to the PRoteomics IDEntifications (PRIDE) database requires the .group files be converted to XML files. ProteomeXchange fully supports both MS/MS proteomics and SRM data submissions. Other types of proteomics data, including ProteinPilot data, is also possible using the partial submission mechanism.
11/09/2018
Academia Omics
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Software
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What is the Format of the Login for Analyst Software? The format of the login for Analyst® software can be in two formats: 1) type in the user name and select the domain from the drop down or 2) log in using user@domain.org or DOMAIN\UserName.
10/31/2017
Analyst Software
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Ekspert 400 AS3 Error Message ERROR SAMPLE-NEEDLE VIALBOTTOM ACTIVATED Ekspert 400 AS3 Error Message ERROR SAMPLE-NEEDLE VIALBOTTOM ACTIVATED
09/04/2016
Academia Omics
|
NanoLC 400
|
What Is the SCIEX OS Software Equivalent to the Area Threshold Feature in Analyst® Software? SCIEX OS software does not have a field for the Area Threshold as found in the Analyst® software quantitation method wizard that allows users to set the criteria for peaks to appear as "not found" in a results table. Instead, a custom flagging rule must be created in SCIEX OS software to enable this type of filtering for peak area.
10/22/2020
SCIEX OS
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What Is the Minimum Accumulation Time in Analyst® TF Software for TripleTOF® Systems? This article provides guidance on the minimum accumulation time that can be entered in Analyst® TF software for TripleTOF® Systems.
09/30/2022
Analyst Software
|
Where Can I find Safety Data Sheets (MSDS) or Certificates of Analysis (CoA)? To find the Safety Data Sheets and Certificate of Analysis for Sciex reagents, navigate to https://sciex.com/tech-regulatory?safetyTerm=4406127&safetyLanguage=English-United+States
12/11/2017
Standards and Reagents
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Where can I download MaxQuant software? MaxQuant software is a quantitative proteomics software package designed for analyzing large-scale mass-spectrometric data sets. It supports all main labeling techniques like SILAC, di-methyl, TMT and iTRAQ, as well as label-free quantification.
12/01/2017
Academia Omics
|
Software
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Can the Sample Injection Volume Be Displayed in an Analyst® Software Results Table? Analyst® software results tables do not have the option to display the sample injection volume from the data file.
05/25/2018
Analyst Software
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Does Analyst® 1.7 Software Support the Windows Long-Term Service Channel? Windows10 and Analyst® software are not supported by the Windows long-term service channel.
04/27/2018
Analyst Software
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MultiQuant™ Reporter: System Out of Memory Error When generating a report in MultiQuant™ software, an error appears: "System out of memory." To resolve this error, more memory can be added to the computer, a 64-bit computer can be used, or one of the two following workarounds can be used.
10/18/2018
MultiQuant Software
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Does the XCMSPlus Software Use MS/MS Data Matching to Identify Metabolites? XCMSplus software does not use MS/MS matching to identify features. Instead, this software identifies features based on the precursor m/z.
11/14/2019
Academia Omics
|
Environmental Industrial
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Pharma CRO
|
XCMS Plus Software
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Can I use the Eksigent 3.12.1 software on a Win7 64 bit PC Instructions on how to configure Windows 7 for use with the Eksigent 3.12.1 software.
07/08/2016
Academia Omics
|
NanoLC 400
|
How to Apply an External Calibration Curve to a Results Table in MultiQuant™ Software In MultiQuant™ software, a previously-created calibration curve can be imported into a results table and applied to the existing unknown samples. In the old results table with the calibration curve that you would like to export, ensure the standard samples are present and select the Process menu. Then select Export Calibration, name the calibration curve data, and click Save.
11/05/2020
MultiQuant Software
|
Where Can I Find a Column Part Number from Eksigent? The provided link lists all micro and nano columns including nano chip columns.
12/01/2017
Academia Omics
|
Environmental Industrial
|
Forensics
|
Pharma CRO
|
Micro HPLC Columns
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cHiPLC
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Micro cHiPLC
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Nano cHiPLC
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NanoLC 400
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How Is a MultiQuant™ Software Report Created in .CSV Format? To create a report in MultiQuant™ software in .csv format, open a results table and then select Create Report under the File menu. Choose a comma delimited report template, and choose CSV as an output format.
01/24/2019
MultiQuant Software
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What Are the Hardware Specifications for the Central Administrator Console for SCIEX OS Software? The hardware recommendations for the Central Administrator Console for SCIEX OS software are for a PC with a minimum of an i5 quad core, a 3 GHz processor or above, a minimum of 20 GB hard drive space, and a minimum of 8 GB RAM.
09/16/2022
Pharma CRO
|
SCIEX OS
|
How to Interface MultiQuant™ Software with a LIMS System via a LIMS Report Template Oftentimes MultiQuant™ software results table data needs to be exported and then interfaced with a LIMS system. This article explains how to indirectly transfer data from results tables created in MultiQuant software to a LIMS system via a report template. The report template creates an output file in CSV format that can then be interfaced with a LIMS system.
11/01/2021
Clinical
|
Mass Spectrometers
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ProteinPilot™ Software 5.0: What Are the Criteria for Including a Peptide in the Feature Tab? The general filters for peptides are listed here. These are applied through the feature tab in ProteinPilot™ software.
09/11/2017
Academia Omics
|
Pharma CRO
|
ProteinPilot Software
|
Use the following protocol to change the port 8081 to resolve the software error that occurs wtih both Sciex OS and MasterView/LibraryView installations: SciexLibraryService rejected the session-establishment request.
07/24/2019
SCIEX OS
|
Restoring Calibration Reference Tables in Analyst® Softare To restore a calibration reference table in Analyst® software, copy the TuneData.tun file over to the current API instrument folder/Preferences folder.
03/15/2018
Analyst Software
|
How to Add a new User into LibraryView™ Software This article explain how to add a new User into the Security Database of LibraryView™ Software 1.0.x. Users need to be added to open the Software.
05/31/2017
LibraryView Software
|
Locating the Name of a Server or PC Using the Command Prompt Window This article describes the DOS commands used to access the name of the server or PC.
05/14/2020
Academia Omics
|
Software
|
What Cable Should I Use To Connect PAL3 to an Agilent Pump when Using Analyst® Device Driver? A sync cable, called the PAL connecting cable APG Remote, should be used to connect the PAL3 autosampler to an Agilent pump when both the devices are configured through the Analyst® Device Driver (ADD).
10/22/2020
|
How Are the Samples and Standards for the aTRAQ™ Kit Stored? The reagents and samples used for the aTRAQ™ kit labeling experiments should be stored at -20 °C or lower. |
Where is the Database for the Central Administrator Console (CAC) Software Stored? Central Administrator Console (CAC) software is used to create and manage projects and users for laboratories using SCIEX OS software on multiple workstations and instruments. The CAC software database is stored in the following location: C:\ProgramData\SCIEX\Clearcore2.Acquisition\CacServerDataBackup
09/16/2022
Pharma CRO
|
SCIEX OS
|
Where Can I Get a New Registration Key for Analyst® Software? If the registration key information for Analyst® software 1.6.x has been lost, navigate to https://sciex.com/analyst-and-analyst-tf-key-generator-registration to obtain a new one.
10/12/2018
Analyst Software
|
The text in the outlier reasons column will change from black to pink if the column value exceeds the cutoff value in MultiQuant™ software. If a query is run after creating the MultiQuant software results table, the flagging color of the query overrides the flagging color of the outlier reasons column in the results table.
10/29/2020
MultiQuant Software
|
Part Number for the Tubing from the Exion/Shimadzu Autosampler to the Column Oven? The tubing connecting the Exion/Shimadzu autosampler to the column oven is stainless steel with connectors and is coated with flexible plastic (600 mm x 0.1 mm). This part can be obtained can be obtained directly from Shimadzu (PN 228-53184-91) or from the online SCIEX store.
10/23/2017
ExionLC AC
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ExionLC AD
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Can I reverse the flow on my Eksigent Nano Chrom XP C18 column when experiencing high back pressure Can I reverse the flow on my Eksigent Nano Chrom XP C18 column when experiencing high back pressure
10/07/2016
Academia Omics
|
ProteinPilot Software
|
For MS3 Experiments, Why Are Two Peaks Adjacent to the Ion of Interest Also Selected? If AF2 (a parameter describing the amplitude of the resonant excitation field) is very large, then off-resonant excitation will begin to increase the kinetic energy of neighboring m/z ions.
03/15/2018
QTRAP Systems
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Analyst Software
|
Resetting Root Directory to Analyst® Data Folder Restores Selexion® DMS Functionality Resetting the root directory to the Analyst® Data folder restores Selexion® Differential Mobility Spectrometer (DMS) functionality and allows the hardware profile to activate in Analyst software.
12/27/2018
SelexION Technology
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Analyst Software
|
What Version of Analyst® Software Is Required to Run Keystone™ Converter Software? Keystone™ converter software requires Analyst® software 1.7.2 along with a patch for the Keystone Converter software to be installed on the data-converting PC.
11/02/2021
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Where Is the License File Saved to Activate a SCIEX Library Used with SCIEX OS Software? For libraries imported into SCIEX OS Software and used with LibraryView 1.x Software, the license file needs to be saved to the directory C:\Program Files\AB SCIEX\LibraryView\LibraryViewFramework\Server in order to unlock the library and activate it.
11/10/2020
LibraryView Software
|
After Upgrading Analyst® Software, Why Do Data Files Include xx.wiff.scan Files? After upgrading Analyst® software, some data files now include xx.wiff.scan files. In the Configure mode in Analyst software, navigate to the Tools and Queue Options menu. Deselect the Use flat files for scan data button to prevent the xx.wiff.scan files from being created.
10/01/2019
Analyst Software
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Device Driver Error During Acquisition with Analyst® Software While Using a Shimadzu LC-40 System While acquiring data with Analyst® 1.7.3 Software while using a Shimadzu LC-40 system, the run will intermittently fail and the following error will appear: "Integrated System Shimadzu LC-40 Controller 0: ERROR: Operation failed. device driver exception." To resolve this error, Hotfix1 for Analyst 1.7.3 will need to be installed when it becomes available. Alternatively, change the LC method so that it is 0.1 min longer than the MS method.
10/14/2022
Analyst Software
|
How can you edit a query file extension? Editing a query file extension requires renaming of the file name.
04/13/2017
Analyst Software
|
MultiQuant Software
|
How Can I Create a Custom Enzyme in BioPharmaView™ 3.x Software? This article describes how to use a different DataDictionary file to add a custom enzyme to BioPharmaView™ software. The BioPharmaView.Data dictionary file cannot be modified. This will result in a reinstall of the software.
11/02/2021
Academia Omics
|
BioPharmaView Software
|
List of CE Capillaries with Pre-burned Detection Windows CE capillaries with pre-burned detection windows are available for purchase; the dimensions and coating information for these products are listed here. |
Can I Change the Sorting Order for Project Folders in Analyst® Software? Analyst® software does not have not have internal sorting logic, so to sort projects, the API functions, FindFirstFile and FindNextFile, are used to retrieve the files from the directory. The order in which the file names are returned is dependent on file system type (NTFS, CDFS or FAT).
10/30/2020
Analyst Software
|
No report styles available in Cliquid 3.2 Unable to create or select report styles after a fresh install of Cliquid 3.2.
07/08/2016
Cliquid Software
|
How Can I Export Results Table Data in Encrypted Text Files in SCIEX OS Software? Users with the administrator role have access to the project settings for secure export in the Analytics workspace under the Projects drop down menu in the SCIEX OS software.
02/11/2022
SCIEX OS
|
What Are the Integration Types Used by Analyst® Software? In Analyst® software, integration types by which the baseline is found and integrated when the peak is found are: baseline-to-baseline, valley, exponential skim, and exponential child.
12/27/2018
Analyst Software
|
How Is the SWATH® Acquisition Variable Window Calculator Excel Sheet Used? This article includes step-by-step instructions on how to calculate variable windows for your SWATH® acquisition experiment and how to generate the input and output list.
10/02/2017
Academia Omics
|
Pharma CRO
|
SWATH Acquisition
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Tuning Solution for the X-Series QTOF System Is Used Too Quickly Quickly depleted tuning solution for the X-Series QTOF System is usually caused by leaks in the Calibrant Delivery System (CDS) plumbing.
03/21/2017
|
The conversion of xml Reporter 3.0.1 to docx Reporter 3.2 fails.
09/04/2016
Analyst Software
|
Accessing ProteinPilot™ Software Searching in the SCIEX Cloud Workspace To log into the SCIEX Cloud workspace and access the ProteinPilot™ software searching features with just your CloudConnect license, follow the instructions below.
04/16/2020
Academia Omics
|
Pharma CRO
|
PeakView Software
|
ProteinPilot Software
|
Why Doesn't the Recalculated Concentration in Excel Fit the Calculated Concentration in Analyst? If I check the calculated results from Analyst for calculated concentration in Excel, the results do not match exactly. Why does this happen and how can I avoid this?
11/29/2017
QTRAP Systems
|
Triple Quad Systems
|
Analyst Software
|
Cliquid 3.2 or MultiQuant 2.1 Installation Failure Component Visual C 2010 Runtime Librariesx86 has failed to install with the following error message Asia. Visual C 2010 Runtime Libraries x86 failed to install.
10/01/2015
Cliquid Software
|
MultiQuant Software
|
When running a search in ProteinPilot™ software as an admin or non-admin user, there should be no difference in FDR report creation as long as full Windows permissions have been provided for Excel report creation. For ProteinPilot software version 5.0.2 with the latest patch (ProteinPilot 5.0.2 Patch for UniProt Issue - Rev. 2), users with a non-admin role may not be able to create reports if the language and font settings are not set to US English.
10/14/2022
Academia Omics
|
Pharma CRO
|
ProteinPilot Software
|
Electronically Resetting the X-series QTOF MS Systems (X500R and X500B) The steps required to reset the X-series QTOF MS Systems (X500R and X500B) are described here.
11/06/2020
|
Working with LibraryView software during data collection by the Analyst software causes the Analyst software to stop acquiring data.
07/08/2016
Environmental Industrial
|
Food and Beverage
|
Forensics
|
LibraryView Software
|
Microsoft Office 365 Cannot Be Activated on SCIEX Acquisition PCs Because of the version of Microsoft Windows that is installed, Microsoft Office 365 may not be able to be activated on certain SCIEX acquisition PCs.
12/02/2022
Software
|
iTRAQ® Reagents: Can Samples Labeled with Both the 4-Plex and 8-Plex Kits Be Mixed? The iTRAQ® Reagents chemistry for 4plex versus 8plex kits is described.SCIEX does not recommend mixing samples labeled with the reagents from the two separate iTRAQ® kits, 4plex and 8plex, due to the differences in the reagent chemistry.
10/16/2018
Academia Omics
|
Pharma CRO
|
iTRAQ Reagent
|
How Does a Client PC Connect to the Central Administrator Console (CAC) Server? The Central Administrator Console (CAC) software client connects to the CAC server using TCP ports 63333 and 44144. Users need to open the Windows firewall port when Windows Defender is used as the default firewall software. If different firewall software is used, then users must follow instructions specific to that software to open these ports.
09/16/2022
Pharma CRO
|
SCIEX OS
|
How Can I Recover My Software License after Replacing My Hard Drive? If your computer hard drive dies and you need to recover your license files, please contact SCIEX technical support for assistance.
06/08/2017
Software
|
Unable To Connect to Shimadzu LC In Hardware Configuration in Analyst® Software When trying to activate a newly installed Shimadzu LC in a hardware configuration in Analyst® Software, an error will appear stating that the LC could not be connected.
09/16/2022
Analyst Software
|
Analyst® 1.7 Software Patch for Windows 10 Update 1709 Installation Error When installing Analyst® 1.7 software with Hotfix 1 and the patch for Analyst 1.7 for Windows 10 Update 1709, the following error message was received, "You must have Analyst 1.7 software installed to install Analyst 1.7 Patch for Windows 10 Update 1709."
03/14/2018
|
Where Can I Find My Service Package for SCIEX OS 1.6.1 Software? Any service package generated for SCIEX OS 1.6.1 software can be found as a zipped (compressed) file at C:\ServicesPackages.
08/09/2019
SCIEX OS
|
Exporting and Importing a Flagging Rule in SCIEX OS Software Flagging rules for IS Recovery can be exported from an existing method in the Analytics workspace of Sciex OS software, and then the exported file can be re-imported into a new processing method using the Export/Import functions in the Flagging Rules screen.
09/29/2019
SCIEX OS
|
X500 series instruments generate wiff2 file formats, but with the newest version of SCIEX OS Software 2.1, they can also generate a .wiff1 file. Only .wiff1 files can be used to perform a ProteinPilot™ software search.
11/02/2021
Academia Omics
|
Pharma CRO
|
SCIEX OS
|
ProteinPilot Software
|
When using MultiQuant™ software with the audit trail and security features turned on, users will find that they are unable to browse to other project folder locations.
12/27/2018
MultiQuant Software
|
What Should I Do if the Scrollbars Are Missing in DiscoveryQuant™ Software 3.0.2 Hotfix2? When working with DiscoveryQuant™ software 3.0.2, the scrollbars are missing, making it difficult to view the data. This issue can be resolved by installing the patch, DiscoveryQuant 3.0.2 Patch for Scrollbars and Plot Resize issue.
11/03/2021
|
How Do I Install SQL Server 2014 for DiscoveryQuant™ 3.0 This article describes the process for building a SQL Server for use with DiscoveryQuant 3.0.
12/22/2015
Pharma CRO
|
DiscoveryQuant Software
|
Does the SCIEX 7500 System with SCIEX OS Software Work with StatusScope® Remote Monitoring Service? Yes, the SCIEX 7500 System with SCIEX OS Software is compatible with StatusScope® remote monitoring service version 2.0.
05/18/2022
Environmental Industrial
|
Forensics
|
Pharma CRO
|
Software
|
How to Export a Statistics Table From SCIEX OS Software to Excel The statistics pane can be accessed from the Views menu in the Analytics module of SCIEX OS software. After opening the results table, select Statistics pane from the Views menu and a new table appears below the results table. To export the contents of the statistics table from SCIEX OS, the table can be copied to Excel by highlighting all rows, and then selecting Ctrl+C. In an open Excel spreadsheet, the selected columns and rows can be pasted using Ctrl+V.
10/29/2020
SCIEX OS
|
The Analyst® Device Driver 1.3 Release Notes The Analyst® Device Driver 1.3 Release Notes are attached. Please consult this guide for the new features and changes from the previous versions.
05/21/2018
Analyst Software
|
This article explain what a Special Acquisition Account is, when to use and how to set it up properly for Analyst Software. This is valid for all Analyst versions from 1.0 up to latest 1.7.3. Also in a non regulated environment, it is recommended to use SAA if Acquiring into a Network.
08/04/2022
Analyst Software
|
Obtaining Intensity Information from an IDA-EPI MS/MS Spectra To obtain the intensity information from an IDA-EPI MS/MS spectra, the ProteoWizard data conversion tool, MSConvert, can convert SCIEX data files (.wiff and .wiff.scan) to other formats using MSConvert besides mzML, such as MGF or txt formats. These non-mzML formats create larger files but provide the spectral data in simple mass/intensity text.
05/13/2020
Software
|
Is the Impurity Feature Available in BPV Flex Software? This is a known issue in the ProteinPilot™ software 5.0.2 and was resolved with a patch.
10/20/2020
|
PA800 How To - Changing Coolant Tubing Changing Coolant Tubing on PA800 System
05/02/2017
Pharma CRO
|
PA 800 Plus Pharmaceutical Analysis System
|
Entering the Formula for a Stable Isotope Labeled Compound in SCIEX OS Software To enter the formula for a stable-isotope-labeled compound in the Components tab of a processing method in SCIEX OS software, some specific rules must be followed. When entering the formula, the atomic mass of the isotope is added before the single letter chemical abbreviation of the element, and then the total number of atoms of each isotope follows the chemical symbol.
10/02/2019
SCIEX OS
|
Does SCIEX OS Software Have an Equivallent Security Configuration to Analyst® Software's Mixed Mode? In Analyst® software, there are three security configuration modes available: Single User, Integrated and Mixed. Are there functional equivalents of all three available in SCIEX OS software? In short, no, there are not.
07/14/2019
SCIEX OS
|
Analyst Software
|
Why Are My Run Times Longer after Upgrading to MPX Software 2.0? Run times may be longer after upgrading to MPX software 2.0 because the acquisition methods may be different for the two streams. Make sure that the methods for both streams are the same.
11/02/2021
MPX Software
|
Description of the options available for interfacing SCIEX software with LIMSELN.
11/01/2018
Analyst Software
|
Cliquid Software
|
MultiQuant Software
|
When building a MRM method in Skyline for use in Analyst® 1.6.1 software, the following error may appear: "Invalid transition list format. Failure parsing numeric value".
05/15/2018
Analyst Software
|
Unable to Install MultiQuant™ Software 3.0.3 on Windows 10 Version 20H2 MultiQuant™ software 3.0.3 is not compatible with and cannot be installed on Windows 10 version 20H2. In order to install MultiQuant software 3.0.3, Windows 10 must be downgraded to an earlier version.
06/22/2022
Software
|
How to setup a diverter valve, including plumbing and Analyst software setup.
02/05/2016
Mass Spectrometers
|
Analyst Software
|
Which Amino Acids in the PepCalMix Are Labeled? The PepCal Mix (P/N 5045759) contains 20 heavy-labeled peptides, with the heavy isotopes incorporated in the amino acids, K and R.
10/09/2018
Academia Omics
|
Pharma CRO
|
Standards and Reagents
|
Keeping a Nano LC/MS System Running after Sample Acquisition Is Completed To keep a nano LC/MS system running after sample acquisition has completed, the LC/MS can be configured two different ways, assuming the Nano Eksigent 400 system is used.
10/08/2018
Academia Omics
|
Pharma CRO
|
Micro LC 200+
|
Nano cHiPLC
|
NanoLC 400
|
Column Name Conflict Error when Running MultiQuant™ Software Reports The error message "The column name 'ion type' conflicts with an existing column" appears when running MultiQuant™ software reports. This occurs when the report uses a query, but gets interrupted midway through the processing, leaving several additional columns in the MultiQuant results table.
12/14/2017
MultiQuant Software
|
Unable to Create Project in Analyst® Software If a project folder is not accessible in Analyst® software, then the root directory must be set to C:\Analyst Data\Projects\. Additional projects and subprojects are set up under this root directory.
05/21/2018
Analyst Software
|
Can Skyline Version 4.2.1 and Higher Process .wiff2 File Formats? Yes , Skyline version 4.2.1 can process .wiff2 files generated using SCIEX OS software.
06/14/2019
Academia Omics
|
Pharma CRO
|
Skyline Software
|
How To Move SCIEX Software License to a Different Computer Description of the steps required to move an already activated SCIEX Software License from one computer to another.
01/28/2019
Software
|
How to Extract Multiple XICs in Separate Windows in Analyst® Software Explore Mode Sometimes in the Analyst® software Explore mode, it's optimal to view individual extracted ion chromatograms (XICs) in separate panes instead of in the same windows when extracting multiple ions from a total ion chromatogram (TIC). To prevent multiple XICs from appearing in the same window, the Appearance Option settings in Analyst software will need to be adjusted.
05/14/2020
Analyst Software
|
How to Display High-Precision m/z Values in LibraryView™ Software Select and open a compound in LibraryView™ Software. Then navigate to the MS/MS Spectra tab to view any MS/MS spectra for the compound. Select the ‘i’ button in spectrum panel, and a peak list with high precision m/z values will be displayed.
04/05/2021
|
Can MutliQuant™ 2.x and MultiQuant 3.x Software Be Installed Side-by-Side on the Same PC? Only one version of MultiQuant™ software can be installed on a PC. Two separate versions of MultiQuant cannot be installed side-by-side.
11/22/2017
MultiQuant Software
|
Ordering Foam Applicators for Cleaning a IonDrive™ QJet Ion Guide The IonDrive™ QJet ion guide can be cleaned with an anti-static foam swab (part number 1017396 or 1017398).
10/18/2018
Mass Spectrometers
|
Creating a Custom Enzyme in BPV Flex 1.0 Software To create a custom restriction enzyme in BPV Flex 1.0 software, locate the digestion agents secction in the BPV Flex DataDictionary.xml file. Type an enzyme definition or Copy/paste a definition for the desired enzyme.
08/09/2019
BioPharmaView Software
|
Does the BioTool Kit MicroApp Require a Separate License in PeakView® Software? The BioTool Kit MicroApp features cannot be accessed in PeakView® software unless a separate license is installed alongside the PeakView® license.
05/11/2018
Bio Tool Kit Software
|
PeakView Software
|
Analyst® 1.7 Software Launch Error: No Such Feature Exists If the license error "No such feature exists" appears when launching Analyst® 1.7 software, install the license file to the C:\ProgramData\AB SCIEX\Analyst\License folder resolve the issue.
05/16/2018
Analyst Software
|
Adding a New Flagging Rule in the Analytics Workspace of Sciex OS Software To add a new flagging rule in the Analytics workspace of SCIEX OS software, open the Analytics workspace. Click Process Method and select New. Then select the Flagging Rules page and click Add Rule.
08/09/2019
SCIEX OS
|
Login into LibraryView software failed Login into LibraryView Software failed.
09/04/2016
LibraryView Software
|
Can I Submit mzIdentML Files from ProteinPilot™ Software 5.x to the PRIDE Repository? This article summarizes the issues with ProteinPilot version 5.0 and mzIdentML created files. Submission of mzIdentML files is still not automated with later versions of ProteinPilot™ software, including version 5.0.x. Complete submissions from ProteinPilot software to PRIDE are not possible, but partial submissions of the mzIdentML are, and this partial submission process is described below.
11/01/2021
Academia Omics
|
ProteinPilot Software
|
Converting Sciex OS WIFF2 Files to the MzML and MzXML Format The Proteowizard tool (http://proteowizard.sourceforge.net/downloads.shtml) for MzML and MzXML conversion has been updated to work with the new WIFF2 files that are produced by SCIEX OS 1.2 and 1.3.
12/22/2017
Analyst Software
|
Restoring Icons to the Analyst® Software Toolbar To restore missing toolbars in Analyst® software, select the Tools menu, and then select the Restore Default Toolbars option. This should restore the icons that were not showing previously.
10/29/2020
Analyst Software
|
Reporter 3.2: How To Report Calculated Concentrations of "<0" or "N/A" If a MultiQuant™ or Analyst® software results table contains values of "<0" and "N/A" for some calculated concentration values, these text values must be converted to a numerical zero value first using an Excel query. These calculated concentration values cannot be filtered into a Reporter Template Suite 3.2 results template using an if statement that selects for calculated concentration values that are less than or equal to zero.
12/16/2019
Software
|
Is the Digital PicoView® Ion Source Compatible with Analyst® TF Software 1.8.x? Both Analyst® TF Software 1.8.x and the software for the Digital PicoView® Nanospray Ion Source will work together with the Windows 10 operating system. This was tested and confirmed separately by both manufacturers, SCIEX and New Objective.
11/09/2020
Analyst Software
|
Windows Folder Permissions Needed for 32 Karat Software Pperation A table of the needed security permissions that allow the 32 Karat software to operate correctly in a Windows operating system environment is shown.
12/26/2018
|
MultiQuant 2.1.1 on a 64 bit pc does not show reporting options MultiQuant 2.1.1 will not show reporting options on a 64 Bit operating system unless 64 Bit Microsoft Office is installed
07/08/2016
MultiQuant Software
|
How do I search an EST or other nucleotide database How do I search an EST or other nucleotide database
12/07/2016
Academia Omics
|
ProteinPilot Software
|
Location of the Event Logs for the MPX 2.0 Driver Software System The event logs for the MPX 2.0 driver software system are saved under C:\Program Data\SCIEX\MPX Driver\Log\.
03/20/2020
MPX Software
|
PA800 How To - Trimming a Capillary Trimming a Capillary
05/02/2017
Pharma CRO
|
PA 800 Plus Pharmaceutical Analysis System
|
Location of the Current Instrument Data File for SCIEX Triple Quad™ or QTRAP® LC-MS/MS 7500 Systems The current instrument data file (current.dat file) for Triple Quad™ or QTRAP® LC-MS/MS 7500 Systems is backed up to a SCIEX OS Software folder located at C:\ProgramData\SCIEX\MassSpec\InstrumentData\YYYYMMDDHHMMSS.
03/31/2021
SCIEX OS
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QTRAP Systems
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Triple Quad Systems
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How To Review Statistics for Standards and QCs in Analyst® Software To review the statistical information for standard and QC samples after creating a results table in Analyst® software, select the statistics button in the software's toolbar. This will open a new window with statistics for the standards and QCs that can be copy and pasted to a spreadsheet.
09/30/2022
Analyst Software
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What Is the Function of the Collision Gas (CAD) on QTRAP® System Instruments? The various functions of the CAD gas are described for the QTRAP® System instruments and the different scan types.
07/14/2017
Academia Omics
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Clinical
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Environmental Industrial
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Food and Beverage
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Forensics
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Pharma CRO
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QTRAP Systems
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Triple Quad Systems
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Is the Analyst® or Analyst® TF Software Backwards Compatible? The Analyst® or Analyst® TF software is only forward compatible.
10/08/2018
Analyst Software
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Where Are the Log Files Located for ProteinPilot™ Software? The log files are needed for troubleshooting error messages in ProteinPilot™ software and can be located at C:\AB SCIEX\ProteinPilot Data\Temp\ProteinPilot.log.
09/16/2022
Academia Omics
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Pharma CRO
|
ProteinPilot Software
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High Mass Cooling in Analyst® Software during Full Scans The High Mass Cooling functionality was introduced to Analyst® software to minimize the negative effects of very high RF voltages on the quadrupole rod arrays. It is used only on certain instruments (5500, and 6500 series in low mass mode only) in order to slightly extend the usable mass range while maintaining optimal ion transmission and sensitivity.
05/04/2018
Analyst Software
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How To Create Metric Plots In MultiQuant™ Software To create a metric plot In MultiQuant™ software, users should highlight the column they wish to see plotted versus the sample index and then select the metric plot icon (trend line with red peaks) in order to view trends such as the peak area of internal standards and analytes.
10/20/2022
MultiQuant Software
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Download a Free Ion Library for LibraryView™ Software A free-of-charge ion library for LibraryView™ software is available from the SCIEX Software Downloads page. No license is required to use the Accurate Mass E&L Open Access HR-MS/MS Spectral Library, the so-called Extractables & leachables library.
06/22/2022
SCIEX OS
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LibraryView Software
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How Is a Special Acquisition Account Setup in Analyst® Software? To select an Acquisition Account Mode, navigate to the Security Configuration menu in Analyst® software and in the Security tab select the type of account, Client or Special Acquisition Administration Account.
10/31/2017
Analyst Software
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How Do I Start the Installation Confirmation Tool in SCIEX OS Software? SCIEX OS 3.1 software has an installation confirmation tool that ensures that the software has been installed correctly. The confirmation tool can be started by tapping or clicking Search on the taskbar and then typing "SCIEX OS Installation Confirmation Tool" in the search box.
03/03/2023
Software
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Using an External Calibration Curve in SCIEX OS-MQ Software To use an external calibration curve with a results table created in SCIEX OS-MQ software, use the Export calibration (and save results...) feature in the Options menu after the calibration curve has been generated.
03/17/2020
SCIEX OS
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Can Regular Expressions (Regexes) Used for Data Filtering in SCIEX OS Software Be Saved? To export and import filter settings so they can be used across multiple results tables and projects in SCIEX OS software, a regular expression (regex) can be created using a custom filter in an existing results table. The custom settings can be exported as a .cset file using the Table Display Settings export feature and reapplied to another table using the Import feature.
10/22/2020
SCIEX OS
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Flags or Custom Results Are Not Showing Correctly on a SCIEX OS Software Report A mismatch of index can occur when internal standard values from a SCIEX OS software results table are processed within a query, causing the text for the reported values to appear bolded and in red, even when there is no reason for flagging these values in the report itself. This phenomena is observed for results tables created in versions of SCIEX OS Software 1.6.1 or lower and has been fixed in versions of SCIEX OS software 1.7 or greater.
11/06/2020
SCIEX OS
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Resolving Analyst® 1.6.3 Software Launch Error: Cannot Find the File Usernameanalyst.exe To resolve the error "Cannot find the file usernameanalyst.exe" when opening Analyst® 1.6.3 software, the format of the Windows username on the computer where Analyst software was installed could not contain a period or a space in the middle of the user name. Reformatting the text of the Windows usernames resolved the issue.
10/02/2019
Analyst Software
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How Can I Install the Free Extractables & Leachables Library in SCIEX OS Software? This article describes how to download and install the free Extractables & Leachables library into SCIEX OS software to test a library matching workflow.
09/16/2022
SCIEX OS
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Causes of the taglet.exe Error in ProteinPilot™ Software The taglet.exe error in ProteinPilot™ software is due to a wide range of issues including incorrect language settings, installation of the software on the incorrect operating system, and the incorrect addition of modifications — to name a few.
11/14/2019
Academia Omics
|
ProteinPilot Software
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MALDI TOFTOF: Can I calibrate using a linear mode acquisition method in batch mode? When calibrating a linear mode acquisition method in batch mode the software reports that a reflector mode acquisition method is required in order to use the batch mode.
03/24/2017
Academia Omics
|
Pharma CRO
|
Top 10 Things Users Can Do to Minimize Contamination of LC/MS Systems Several things can be done to reduce the contamination of LC/MS systems that require minimal time but increase uptime and robustness. Here, we present a list (in no particular ranking) of the top ten things to consider when trying to lower instrument contamination.
05/21/2021
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Upgrading MultiQuant® software to 3.0.3 Version Results in Access is Denied Error After upgrading MultiQuant® software 3.0.2 to 3.0.3 on Windows 10, the software initially launched. But when the software was accessed later, an error was received: "Access is denied".
05/23/2019
MultiQuant Software
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Unlocking the Secure PDF Files Created by SCIEX OS Software To unlock a secure PDF file created using SCIEX OS software reporter, open the document in a web browser and then print the newly opened document using either Microsoft Print to PDF or Save As PDF.
10/04/2019
SCIEX OS
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How to Determine if the Acquisition PC Has a Bad Ethernet Card? This article summarizes some issues that might contribute or confirm a bad network card.
04/16/2020
Mass Spectrometers
|
Understanding and optimizing signal-to-noise calculation in the 32Karat software This document provides an overview of the S/N calculation and optimization in the 32Karat software.
04/05/2019
PA 800 Plus Pharmaceutical Analysis System
|
How Can the Data from Two Experiments Acquired within One Period Be Separated in Analyst Software? Data from two or more experiments acquired within one period can be separated by opening a data file in Explore mode and double clicking the green arrow. |
What solutions should be used for the nano 2D LC Eksigent pump seal rinse and the Autosampler wash What solutions should be used for the nano 2D LC Eksigent pump seal rinse and the Autosampler wash
10/07/2016
Academia Omics
|
NanoLC
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Is It Possible To Convert a Shimadzu High-Flow LC to a Microflow LC System? In order for a microflow LC system to perform optimally, the correct LC hardware must be installed. For example, a high-flow Shimadzu LC-20AD system cannot simply be converted to a microflow system because the 20AD is not equipped with the correct type of solvent mixer.
12/09/2021
Pharma CRO
|
Molecular Ion Not Appearing during Compound Optimization Adding mobile phase to the analyte or increasing its concentration during compound optimization may help improve ionization.
05/11/2018
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ProteinPilot™ 5.x Software: Incorrect Result Output for Instrument Names in the Group File ProteinPilot™ software uses the incorrect mass spectrometer name in its group file output file. When a TripleTOF® 5600 system was selected, the group file contains the name QSTAR® Elite instead for system information. This causes the wrong results to be output; if the incorrect instrument name is used, then the incorrect tolerance settings are applied.
03/16/2018
Academia Omics
|
Pharma CRO
|
ProteinPilot Software
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What Is the Organic Solvent Used with iTRAQ® Reagents during Shipment? All iTRAQ®, aTRAQ™ and mTRAQ® reagents are shipped in acetonitrile from the factory. |
Adding Acquity Plate Definitions into Analyst® Software To add the definition of the Acquity 96-well, 1-mL plate (using ANSI-96well1mL.plate file) to Analyst® software, a plate definition file must be acquired from Waters.
12/20/2017
Analyst Software
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How to Export and Import Processing Methods in SCIEX OS Software Processing methods can be exported or imported in the Analytics workspace of SCIEX OS software.
05/04/2022
SCIEX OS
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Can I Modify or Add an Enzyme in Bio Tool Kit Software? The Bio Tool Kit software micro-app characterizes biomolecules within SCIEX OS and PeakView® software through features such as intact protein spectral deconvolution and manual sequence tagging. The software does not allow users to add or modify proteolytic enzymes themselves, but there is a workaround that can be used to modify an existing enzyme.
05/17/2022
Academia Omics
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Pharma CRO
|
Bio Tool Kit Software
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SCIEX Software Activation with Online Workstation How to activate Analyst, MultiQuant or SCIEX OS software with a computer which is connected to the Internet
11/19/2018
Software
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When Does Analyst® Software Start Generating the Archive for Audit Trail Records? Once the instrument audit trail or a project audit trail contains 1000 audit records, the Analyst® software automatically archives the records and begins a new audit trail.
05/05/2022
Analyst Software
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Are PPGs Used for Tuning and Calibrating the QTRAP® or TripleQuad™ LC-MS/MS 7500 Systems? No, a new calibrant, the MS Tuning Solution, was introduced for tuning and calibrating the QTRAP® or TripleQuad™ LC-MS/MS 7500 Systems.
12/04/2020
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Separating Concatenated .wiff Files in Analyst® Software To separate concatenated .wiff file sets, a script called Make Subset File is used. This script might have limitations for Analyst® and Analyst TF software because it depends on the experiments in the file (i.e., the script does not work for IDA methods). The script is found on the Analyst TF software CD in the folder \Extras\Scripts\Make Subset File.
12/20/2017
Academia Omics
|
Pharma CRO
|
Analyst Software
|
What File Format Can Be Used for RNA Data Sets in the OneOmics™ Suite 3.4? To import RNA data sets into the OneOmics™ suite, the RNA data sets need to be in the Cuffdiff output file format from CuffLinks.
03/03/2023
Academia Omics
|
Software
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Is the Settings File for the Central Administrator Console (CAC) Software Forward Compatible? Yes, the Central Administrator Console (CAC) software settings are forward compatible with future versions of the CAC for SCIEX OS software. This means that the setting files (.eac files) from older versions of the CAC software can be imported into newer CAC versions (when they become available), and all the information regarding users, workstations, projects and workgroups will be able to imported into a new version or new installation of the CAC software.
09/30/2022
Pharma CRO
|
SCIEX OS
|
To Make Reporter Tags Visible in a Report Template Unblock Them If a report template is emailed or transferred to another computer and then opened, the xml tags may not be visible because they were blocked for security reasons.
10/10/2019
SCIEX OS
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Analyst Software
|
MultiQuant Software
|
How to Open a Reporter Query Used with SCIEX OS or MultiQuant Software Report Templates This article discusses the three ways to open a query (a file with the extension .query), a file linked to a report template that can be used to perform more complicated calculations or sorting functions in a results table.
11/18/2020
SCIEX OS
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Analyst Software
|
MultiQuant Software
|
Surfactant Contamination in Negative mode scans A summary of the findings from an investigation into the identity of background Ions found in -ve mode electrospray mass spectrometry with suggestions to help minimize their impact on analysis.
10/02/2017
Mass Spectrometers
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Is the MPX™ Driver Software System Compatible with Analyst® MD software? The MPX™ driver software system is not supported with Analyst® MD software. Compatible LC systems are listed in the installation guide for Analyst MD software.
03/20/2020
Clinical
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Forensics
|
Analyst Software
|
How Do I Find the Build Number for Analyst® Software Version 1.7.3? With Analyst® software version 1.7.3, the build number no longer appears in the About Box due to a new requirement that the displayed information in Analyst 1.7.3 had to be in sync with the MD version of the software. Users can check the version (build) number by navigating to the Programs and Features section of the control panel by using the Details view to see the version for each installed software.
08/08/2022
Software
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Unable to Export IDA Table From SCIEX OS Software into Excel When viewing IDA data in the Explorer mode of SCIEX OS software, the IDA table data will not export into Excel. Exporting the data directly to Excel is not supported in SCIEX OS software, and the best workaround is to select the top row of the table and select Ctrl, Shift, End to copy the IDA data directly to Excel.
07/23/2022
SCIEX OS
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How to perform System Check on Sciex Exion 1.0 systems from Analyst® How to perform System Check on Sciex Exion 1.0 systems from Analyst®
08/18/2023
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No, when using Analyst® software for network acquisition, users should not create a project with the name API Instrument in the network root directory. Doing so causes the instrument audit trail events to be recorded in the API Instrument project on the network instead of in the local API Instrument project.
08/22/2023
Software
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Do Analyst® Software and Analyst Administrator Console (AAC) Support Cross-Domain Logins? No, the Analyst® software and the Analyst Administrator Console (AAC) do not support cross-domain logins. The computer where Analyst software is installed, the AAC computer, and the network users should be on the same network domain.
08/23/2023
Software
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Where Are the Report Templates Located for Analyst® Software? To edit a report template or add a new template to create reports in Analyst® software, users must access the folder where report templates are stored. The report template files are located in the Templates sub-folder within the API Instrument project folder in the Analyst Data root directory.
08/24/2023
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How Do I Select a Compound Database in DiscoveryQuant™ Software? To select a compound database in DiscoveryQuant™ software, select the Data menu, and then select Database Selection. The Compound Database Selection dialog will open, and the database options are indicated in this window.
08/24/2023
Software
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What Are the Minimum Cycles Needed To Obtain Quality Optimizations in DiscoveryQuant™ Software? When setting up an optimization experiment in DiscoveryQuant™ software, the minimum number of cycles needed to obtain quality optimizations is two.
08/24/2023
Software
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How Are Entries Added to the Compound Database in DiscoveryQuant™ Software? To add entries to the compound database in DiscoveryQuant™ software, the Edit Compound Workspace must be opened.
08/24/2023
Software
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What Is the Username and Password for the Empty Compound Database in DiscoveryQuant™ Software? To open the empty compound database - CompoundDB3.mdb - for DiscoveryQuant™ software, a username and password are required. The username is Admin and the password is !DQO2.
08/24/2023
Software
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How Is the Analyst Response Factor Column Generated in SCIEX OS Software? In the SCIEX OS Analytics workspace, Response Factor is not one of the standard columns that users can select from the results table, but it can be created and added to the results table by adding a custom column.
08/24/2023
Software
|
Why Can't I Print My Audit Trail Record from Analyst® Software? For Windows 10 operating systems, if the user who logs on to the Analyst® software in mixed mode is different than the user who logged on to the computer, then the audit trail record printing function will not be available.
08/24/2023
Software
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How Can I Customize the Project Information in DiscoveryQuant™ Software? To customize the project information in DiscoveryQuant™ software, open the Setup Optimization workspace.
08/24/2023
Software
|
Can the New Dry Pump MSR 90 for the 6500+ System Be Installed with Analyst® Software? The new Dry Pump MSR 90 can only be operated with SCIEX OS software on the 6500+ system. It is not compatible with the Analyst® software for data acquisition.
09/01/2023
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Canned Calculation for SANTE Guideline 12682_2019 - C16 - Available for SCIEX OS Software This article provides information on the custom calculations required for processing data according to the guidance found in SANTE 12682_2019 - C16. The guidance requires that analyte response in the extracted pesticide samples should lie within the range tested for calibration standards. These calculations were created to provide a ready-made solution for determining which samples will need to be re-injected in pesticide reports.
08/31/2023
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Maintaining the Ion Spray Voltage when Using the Nano OptiFlow® Turbo V Ion Source In order to maintain the ion spray voltage while operating the nano OptiFlow® Turbo V ion source, one option is to leave the mass spectrometer in Standby mode (LC pumps are turned off and some instrument voltages are turned off) at the end of a run.
09/01/2023
Academia Omics
|
Pharma CRO
|
NanoLC 400
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How To Install the DIA-NN Software 1.8.1 To Process SCIEX WIFF Files? To process SCIEX data files (.wiff) with the DIA-NN software, the DIA-NN software must be installed using the downloaded executable file. In addition to installing DIA-NN software, the ProteoWizard software must be installed and the dll files in the ProteoWizard installer folder named Clearcore and SCIEX must be transferred to the DIA-NN installer folder.
09/01/2023
Academia Omics
|
Software
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A library-free search, or direct-DIA (data-independent acquisition), is a proteomics strategy to identify unknown proteins and peptides by generating a theoretical spectral library from a FASTA file and then searching the DIA data against this spectral library using the DIA-NN software.
09/01/2023
Academia Omics
|
Software
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Which Molecule Profiler Software Version Can Process EAD Fragmentation Data? The Molecular Profiler software 1.3 is embedded in the SCIEX OS software version 3.1.6 and can assign structures by using fragments from both electron-activated dissociation (EAD) and collision-induced dissociation (CID) techniques.
09/01/2023
Academia Omics
|
Pharma CRO
|
Software
|
How Does the Channel Alignment Function on a SCIEX TripleTOF® System? The purpose of channel alignment is to re-align the signals from each detector/TDC channel in time on a TripleTOF® system. Channel 2 is used as the reference channel, and a simple linear transformation is applied to the other three channels to align them to the refrence.
09/01/2023
Academia Omics
|
Pharma CRO
|
QTOF Systems
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DIP Switch Positions when Connecting Agilent LC Systems to SCIEX Mass Spectrometers When connecting Agilent LC Systems to a SCIEX mass spectrometer, the dual-in line packet (DIP) switches on the Agilent LC systems should be in the down (off) position, except for switches 7 and 8 which must be in the up position for the pump and detector.
09/15/2023
Mass Spectrometers
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Software
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How Do I Work with LC Devices Not Directly Controlled by SCIEX OS Software? To synchronize signals between a SCIEX mass spectrometer, the SCIEX OS software and LC devices that are not directly controlled by the SCIEX OS software, contact closure can be used.
09/16/2023
Software
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How can I generate a Batch-Import-Template for SCIEX OS to set up my manual LIMS connection? SCIEX OS can import batch information from a LIMS system if the import file (*.csv/*.txt) follows defined layout rules. To have the proper layout an example batch can be exported from SCIEX OS to be used as a template.
09/07/2023
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How to Save Application, System and Security event logs in Windows®10 The Windows event logs often contain crucial data about the performance of SCIEX software. Follow this guidance to save your System, Security and Application event logs so that they can be analyzed by the SCIEX support team.
09/08/2023
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ProteinPilot™ software 5.0.3 is needed to view group files from OneOmics™ suite In order to view group files generated by ProteinPilot™ software from the OneOmics™ suite, users must install ProteinPilot software 5.0.3, a beta version of the software that is not currently available from the SCIEX software downloads page. The link to the installer is provided in this article.
09/18/2023
Academia Omics
|
ProteinPilot Software
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Where is the folder location for LibraryView 1.6 software license file? This will help the user to access the existing LibraryView (version 1.6) license file, or it could help user to place the recently obtained license file into the correct folder on the computer.
09/21/2023
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Error with MPX™ Software 1.2: Unable To Access Autosampler Database When launching MPX™ software 1.2 on a Windows 7 64-bit operating system, an error appears, "Unable To Access Autosampler Database".
09/22/2023
MPX Software
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How to initiate injection counter in Analyst® Software version 1.7.3 How to initiate injection counter in Analyst® Software version 1.7.3
09/22/2023
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What to do if a service package cannot be created in SCIEX OS or Analyst® software? If a service package cannot be generated in SCIEX OS or Analyst® software, the event logs, installed programs and other important system information can be manually provided for trouble shooting purposes.
09/22/2023
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What are Metric Plot Settings in SCIEX OS software and where are they saved? Metric Plot Settings allow the user to customize the appearance of the Metric Plot pane.
09/22/2023
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How do I create a new entry in the automatic calibration editor in SCIEX OS software For the batch calibration of high-resolution instruments within SCIEX OS software the Automatic Calibration Editor can be used. Some "ion reference tables" are pre-installed, but they can be customized, or new tables can be added.
09/22/2023
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Locating the List of Isotopic Amino Acid Symbols in Bio Tool Kit Software The Bio Tool Kit microapp can be used for peptide sequencing or fragment matching in PeakView™ or SCIEX OS software. The one-letter codes for amino acids are used when entering potential fragment ions. To represent isotope-labeled amino acids, square brackets encompassing the mass shift are used to the right of the one-letter code. In Bio Tool Kit software, the information for all heavy amino acids is stored in the AA Modifications tab in the Mass Calculator.
09/22/2023
Academia Omics
|
Bio Tool Kit Software
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How to perform a source back out (Pyrolysis) in SCIEX OS software or Analyst® software? In some circumstances, e.g., infusion of very high concentrations of standards or matrices, the source may be contaminated. Baking out helps to remove the impurities.
09/22/2023
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How to modify ParameterSettings for APCI “Compound Optimization” in Analyst® software? The automated “Compound Optimization” within Analyst® software takes over the values set in the parameter settings. The values are optimized for infusion flows around 10 µl/min. For APCI, a flow of at least 200 µl/min is needed, which is why the values for the gases and the temperature must be adjusted.
09/22/2023
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How to initiate and activate Auxiliary traces in Analyst® Software version1.7.3 How to initiate and activate Auxiliary traces in Analyst® Software version1.7.3
09/22/2023
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How do I create a Shortcut in SCIEX OS Software and which shortcuts are available? Overview of available combinations of keystrokes that provides easier access to a command or operation in the SCIEX OS software.
09/22/2023
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Purpose of a Lockfile Alongside a Results Table File in Analyst® Software In Analyst® Software, when opening a results table, an additional file - the lockfile - appears in the Quantitation Results folder for a particular project. The purpose of the lockfile is to prevent a second user from opening the same results table simultaneously and trying to modify it.
09/22/2023
Analyst Software
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Changing the Y-Axis Scale from Relative Intensity Percent in Analyst® Software, When opening raw data in Analyst® software, the Y-axis label reads Rel Int. % with values from 0-100% instead of showing the true intensity value. In the Appearance Options window, select Other Graph Options. Under Percent Y Axis, change the value under the Chromatogram column from Yes to No to set the Y-axis scale back to intensity.
09/22/2023
Analyst Software
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Calculating Mass Properties using a Compound's Formula In Analyst® Software The mass properties of a compound (e.g., average mass, exact mass, nominal mass) can be calculated from its chemical formula using the calculators found in the Tools menu in Analyst® software.
09/22/2023
Analyst Software
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How To Change the Instrument Idle Time In SCIEX OS Software After a set time (the instrument idle time) has elapsed, the system will go into Standby state – whereby the LC pumps, column oven and some mass spectrometer voltages are turned off. To change the instrument idle time in SCIEX OS software, navigate to the Configuration pane, and select the Queue tab. The instrument idle time can be changed by typing the desired time into the field.
09/22/2023
SCIEX OS
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How to reduce matrix effect and increase analyte signal in extracted samples? Presence of matrix could result in lower analyte signal and reducing matrix effect could potentially increase signal and result in better (lower) limits of detection
09/25/2023
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What is the maximum project size in the SCIEX OS Data folder that still permits software efficiency? There is no limit on the number of projects created in the SCIEX OS Data folder. Additionally there is no limit to the number of subproject folders under a current project.
10/05/2023
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How is the Default Column 'Asymmetry Factor' calculated in SCIEX OS? Asymmetry Factor: Asymmetry factor is a measurement of how well the peak matches the ideal peak shape. As = b/a where b is the distance from the peak apex to the trailing edge of the peak measured at 10% of peak height and a is the distance from the leading edge of the peak to the peak apex measured at 10% of peak height. If As > 1 : tailing, et si As < 1 : fronting
10/04/2023
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Certificates of analysis (CoA) are available for various reagents; however for proteases such as trypsin and beta galactosidase that are sold by SCIEX, no CoA is available.
10/05/2023
Standards and Reagents
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Where is the file for the hardware profile used in Analyst® or Analyst TF software located? The file corresponding to the hardware profile used in a Analyst® or Analyst TF software is located in the API Instrument project in the Analyst Data folder.
10/06/2023
Analyst Software
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How To Ramp Parameters in SCIEX OS Software during Compound Optimization When using SCIEX OS software to optimize compounds that are being infused using a syringe pump, it is possible to ramp individual compound parameters such as collision energy (CE), entrance potential (EP), and collision cell exit potential (CXP), and Q0 dissociation (Q0D). This process may be preferred to guided MRM optimization in the event that a more manual and controlled optimization is desired.
10/06/2023
SCIEX OS
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Where are print templates located in SCIEX OS software? A new print template feature appears in SCIEX OS software starting in version 3.1 that allows for batch, queue, and processing methods to be printed for record-keeping purposes. The templates can be accessed from the Configuration tile by selecting the Print Templates tab.
10/06/2023
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Impermissible Symbols for Root Directory Paths and Project Names in SCIEX OS Software There are some symbols which cannot be used when naming a root directory path or a project in SCIEX OS software. They are detailed in this article.
10/06/2023
SCIEX OS
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What version of SCIEX OS software includes a tile for Biologics Explorer software? A tile for Biologics Explorer (BE) software appears in SCIEX OS versions 3.1.5 and higher. The BE software can be launched from this tile, but the BE software needs to be installed from a separate installer as described in this article.
10/06/2023
Academia Omics
|
Pharma CRO
|
SCIEX OS
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Enabling ChemSpider funtionality in SCIEX OS software To enable the ChemSpider feature within SCIEX OS software, the ChemSpider add-on license must be added to the SCIEX OS software program files and the Formula Finder feature must be enabled in the processing method.
10/06/2023
Clinical
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Environmental Industrial
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Forensics
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Pharma CRO
|
Software
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How to report Dell PC hardware issues for computers not under service contract For Dell computers experiencing hardware issues that were purchased from SCIEX but are no longer under a service contract, users can reach out directly to Dell for support using the link provided in this article.
10/06/2023
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How can I set up contact closure in SCIEX OS software for my SCIEX instrument? To set up contact closure for a SCIEX mass spectrometer to communicate with an external LC system, the contact closure check box must be selected in the instrument's hardware profile in SCIEX OS software. SCIEX OS software 3.1.6 supports many of the same legacy instruments that were controlled by Analyst® software even if contact closure is required for a third-party vendor LC system.
10/09/2023
SCIEX OS
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Removing an ESI probe to change the capillary on a SCIEX mass spectrometer Capillaries can get blocked and will need to be replaced from time to time to maintain high quality spray from an electrospray ionization (ESI) probe. This article provides a link to a YouTube video that shows how to remove an ESI probe to change the capillary on a SCIEX mass spectrometer.
10/09/2023
Mass Spectrometers
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Upgrading the Biologics Explorer software General steps for the upgrade process for the Biologics Explorer (BE) software are described in the release notes. Versions of SCIEX OS software 3.1.5 and greater, have an embedded BE software tile. For those versions of SCIEX OS software containing the BE tile, the SCIEX OS software must first be closed, and all SCIEX OS services stopped before proceeding with the BE software upgrade.
10/09/2023
Academia Omics
|
Pharma CRO
|
Software
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Will my old workflow templates or data be lost when upgrading Biologics Explorer software? The Biologics Explorer software will automatically save all workflow templates and data from previously installed versions.
10/09/2023
Academia Omics
|
Pharma CRO
|
Software
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How to upgrade your SCIEX mass spectrometer's firmware after upgrading the SCIEX OS software After upgrading SCIEX OS software on an acquisition PC, the instrument firmware also needs to be upgraded. To do this, follow the instructions in the SCIEX OS software installation guide in the sections MS FW Updater Utility and Mass Spectrometer Firmware Versions.
10/08/2023
SCIEX OS
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Where can I find general security recommendations for my PC running SCIEX software? The security guidance provided in the link in this article contains supplemental instructions for protecting acquisition and processing computers that are running SCIEX software. This guidance is intended to supplement rather than replace current IT policies, requirements and practices.
10/09/2023
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Adding MS/MS information to the MRMHR processing method's Components tab in SCIEX OS software To add the MS/MS information to a MRMHR processing method in SCIEX OS software, a compound name, a unique name for the fragment ion, and the fragment mass information are required in the table under the Components tab.
10/09/2023
SCIEX OS
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What MRM modes are available on SCIEX TripleQuad and QTRAP systems? There are four different multiple reaction monitoring (MRM) modes that can be acquired using SCIEX TripleQuad or QTRAP systems with SCIEX OS software: MRM, scheduled MRM, scout triggered MRM RT mode, and scout triggered MRM group mode.
10/09/2023
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Where are print templates stored in SCIEX OS? A new print template feature appears in SCIEX OS software starting in version 3.1 that allows for batch, queue, and processing methods to be printed for record-keeping purposes. The templates can be accessed from the Configuration tile by selecting the Print Templates tab. Users can customize templates and apply them to specific projects.
10/11/2023
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Restoring Missing Toolbars and Menus in Analyst® Software If the toolbars in Analyst® software disappear, leaving a blank, grey area. they can be restored using the command ALT T.
10/13/2023
Analyst Software
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Common Installation Errors for SCIEX OS Software This article describes the common installation issues that occur when installing SCIEX OS software for the first time. To install SCIEX OS software successfully, the Installation Guide should be consulted and each section should be read prior to installing the software.
10/13/2023
SCIEX OS
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Recommendations for lower and upper temperatures for an Exion 2.0 method in Analyst® software When working with an acquisition method that uses an Exion 2.0 LC system in Analyst® software, the lower and upper temperature settings should be set slightly higher or slightly lower, respectively, than the safety limits to prevent column oven errors.
10/13/2023
Software
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Can two analytes have the same transitions in an MRM method in SCIEX OS software? Occasionally two different analytes in the same MRM method in SCIEX OS software may have identical Q1 and Q3 masses for their respective MRM transitions. The question is if this could cause problem in quantitation and what should the user do to avoid errors.
10/13/2023
SCIEX OS
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Can a different user log into Analyst® software set to integrated or single user mode? No, opening the Analyst® software as a different user when the security configuration is set to integrated mode or single user mode is not supported.
10/13/2023
Software
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How To Change the Number of Available Rows in the Batch Workspace in SCIEX OS Software In SCIEX OS software, it is possible to change the number of available rows in the batch. To do this, select the View button in the top right of the batch workspace.
10/13/2023
SCIEX OS
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In BioPharmaView™ software, the MS2 score evaluates the quality of a match between MS/MS peaks and a set of theoretical fragments. The MS2 score is based on the probability of the MS/MS peaks matching the set of theoretical fragments of the molecule by chance. The score is calculated automatically by the software.
10/13/2023
Academia Omics
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Pharma CRO
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Biologics Explorer
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How To Utilize the Quick Batch Option in SCIEX OS Software A new option for creating batches quickly was introduced in SCIEX OS software version 3.1.6 and is called Quick Batch. To utilize Quick Batch, an icon in the upper right corner of the Batch screen will need to be selected.
10/13/2023
SCIEX OS
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Error when Opening Analyst® Software: Error 1067 After installing Analyst® software 1.7 alone or with Hotfix 1, attempting to open the software results in an error: Error 1067: The process terminated unexpectedly.
10/13/2023
Analyst Software
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The Metabolomics Workflow in OneOmics™ Suite 3.4 Offers a New NIST Library Search The OneOmics™ suite 3.4 offers a new feature in its metabolomics workflow where the NIST library can be selected as a library option in the Merge workflow.
10/13/2023
Academia Omics
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Pharma CRO
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Software
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How To Create Personalized Toolbars in Analyst® Software To create custom toolbars In Analyst® software and have more personalized access to shortcuts and icons, select the View menu and click on Toolbars. Selecting the New or Customize options will allow for new new toolbars to be created or for customized icons to be added to the toolbars.
10/13/2023
Analyst Software
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Reporter 3.2 Error In Analyst® Software: Unable To Cast COM Object When attempting to generate a report in Analyst® software with Reporter 3.2, an error appears immediately after clicking on create report: Unable to cast COM objectnof type System_ComObject' to interface.
10/13/2023
Analyst Software
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Accessing ProteinPilot™ Software Searching in the OneOmics™ Suite To log into the SCIEX Cloud workspace and access the ProteinPilot™ software searching features with a CloudConnect license, follow the instructions below.
10/13/2023
Academia Omics
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Pharma CRO
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PeakView Software
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ProteinPilot Software
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Can SCIEX OS software be used for acquisition on all SCIEX instruments? To determine if a particular version of SCIEX OS software supports acquisition on a SCIEX instrument, please consult the installation guide for that version of the software. SCIEX OS software does not support acquisition on legacy instruments such as the API™ 3200 and 4000 systems.
10/13/2023
SCIEX OS
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How to set Root Directory in SCIEX OS Software? Per default, the root directory of SCIEX OS Software is set to C:\SCIEX OS Data. The Managment part of the software provides the possibility to define another root directory path and folder name.
10/13/2023
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Performing a ProteinPilot software search with the Mascot server enabled ProteinPilot™ software 5.0.1 can perform searches using the Mascot server. To use the Mascot server, a license is required, and this must be purchased from Matrix Science. Step-by-step instructions are provided in this article for setting up a search with ProteinPilot software 5.0.1 and Mascot version 2.6 or higher.
10/13/2023
Academia Omics
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ProteinPilot Software
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Considerations when Creating a Library-Free Proteomics Experiment without the OneOmics™ Suite Library-free proteomics experiments require highly reproducible sample-handling protocols and data analysis and can be done directly in DIA-NN software without any other SCIEX software or ion libraries.
10/13/2023
Academia Omics
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QTOF Systems
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How to change source, gas and other default acquisition method parameters in Analyst® software? When a new method is opened in Analyst® software, the source and gas parameters, including the declustering potential (DP), the collision energy (CE) and the collision cell exit potential (CXP), are populated based on the software's default parameters. Automatic compound optimization method also uses these default values.
10/14/2023
Analyst Software
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Is PeakView® software required when processing data in the OneOmics™ suite 3.4? PeakView® software 2.2 is not required when processing data in the OneOmics™ suite 3.4, but it is required to upload data to the OneOmics suite using the CloudConnect app.
10/14/2023
Academia Omics
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Pharma CRO
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PeakView Software
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Common installation issues when upgrading SCIEX OS software Some of the most common issues encountered while upgrading the SCIEX OS software and how to prevent them are listed here. Please consult the SCIEX OS software installation guide found in the installer package for step-by-step instructions for correctly upgrading the software.
10/14/2023
SCIEX OS
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Understanding the ion source parameters in Analyst® and SCIEX OS software: GS1, GS2, TEM and CUR For mass spectrometry acquisition methods in Analyst® or SCIEX OS software, values will need to be set for source parameters that influence the degree of ionization in an electrospray ionization (ESI) source. These values include GS1, GS2, TEM and CUR gas.
10/17/2023
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What Curtain Gas Settings Should Be Used on SCIEX 3200, 4000 and 5000 Series Systems? The curtain gas (CUR) is an important parameter that protects SCIEX mass spectrometers from contamination. The proper amount of curtain gas depends on the LC flow introduced into ion source and the model of SCIEX mass spectrometer used. This article explains the CUR value used for SCIEX 3200, 4000 and 5000 series systems.
10/17/2023
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What Curtain Gas (CUR) Settings Should Be Used on SCIEX 3500, 4500 and 5500 Systems? The curtain gas (CUR) is an important parameter that protects the mass spectrometer from contamination. However, the proper amount of curtain gas depends on the LC flow introduced into ion source and the model of SCIEX mass spectrometer used. This article provides the CUR settings for the SCIEX 3500, 4500 and 5500 (5500+) series systems.
10/17/2023
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How to check if the CAD gas is properly working in Analyst® software The collision associated dissociation (CAD) gas is an inert gas that breaks parent compound ions into smaller fragments, making it an important component of multiple reaction monitoring (MRM) methods in Analyst® software. It is introduced by diffusing a small stream of nitrogen through a small orifice into the Q2 of a mass spectrometer. On rare occasions, this orifice might become blocked or out of calibration.
10/18/2023
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Why do extracted samples and quality controls have lower signal compared to neat standards? When a sample or a spiked quality control is extracted, the signal is usually lower than that of the corresponding standard made in pure solvents.
10/18/2023
Mass Spectrometers
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Standards and Reagents
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Batch submission error in Analyst® software: Exceeding the maximum number of waiting samples When submitting a batch in Analyst® software, an error message appears: You are exceeding the maximum number of waiting samples configured in the queue options. The solution is to increase the maximum number of waiting samples in the Queue Options under the Settings menu in Configure mode.
10/18/2023
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What is the best way to flush a liquid chromatography system to remove contamination? Contamination of a liquid chromatography (LC) system usually requires flushing the system with an organic solvent to remove unwanted background. Here an effective way to flush the entire LC system is discussed.
10/18/2023
Mass Spectrometers
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Which mass spectrometers and ion sources are supported by SCIEX OS software? If a new flow rate is desired for a LC/MS experiment, a different ion source may be needed for your SCIEX mass spectrometer. Included here is a list of current mass spectrometers and ion sources that are supported by the most recently released of SCIEX OS software, version 3.3.
10/18/2023
SCIEX OS
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Mass Spectrometers
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Calibration peak list is missing during instrument optimization in Analyst® software During instrument tuning and calibration in Analyst® software, the calibration peak list can be obtained by right clicking on the final spectrum and selecting the List Data option. This will open a new pane that contains the calibration peak list. In this tab, the exact expected masses of the calibration components (e.g., PPG positive) are listed.
10/18/2023
Analyst Software
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Where can I read the vacuum gauge pressure for a SCIEX mass spectrometer in Analyst® software? For current vacuum gauge pressure readings, double click on mass spectrometer icon at the bottom right corner of Analyst® software to open the MassSpec Detailed Status window. Under the Vacuum System Status section, the real-time readout for the vacuum gauge pressure is visible.
10/18/2023
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A YouTube video demonstrates how to replace the electrode in the SCIEX ion source that is compatible with an Eksigent microLC 200 system connected to a SCIEX mass spectrometer and operated by the Analyst® software.
10/20/2023
QTRAP Systems
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Triple Quad Systems
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Inputting known concentrations of analytes into a batch in SCIEX OS software In SCIEX OS software it is possible to input known concentrations of analytes and internal standards for Quality Control and Standard sample types. This prevents having to add the values directly to the results table and saves time when analyzing data.
10/20/2023
SCIEX OS
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How can I quantify efficiency of my extraction method in SCIEX OS software? Extraction efficiency is the percentage of analyte recovered through the extraction process, from the start of extraction to the final step of sample preparation prior to LC/MS analysis. This article explains how to quantify the extraction efficiency in SCIEX OS software.
10/19/2023
SCIEX OS
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Mass Spectrometers
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What are the suggested time intervals when using a diverter valve? Efficient use of diverter valve will keep the mass spectrometer source and ion optics from unnecessary and excessive contamination. This article provides guidance on how to set an appropriate time range for use of a diverter valve during an acquisition method.
10/19/2023
SCIEX OS
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Mass Spectrometers
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Analyst Software
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How is low resolution set up and tuned in Analyst® software? To set up low resolution for mass calibration in Analyst® software during instrument optimization, users can choose unit and low resolution and then set it up the parameters accordingly under the Tuning Options screen.
10/19/2023
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How to Reduce the Column Pressure during Liquid Chromatography? When a new liquid chromatography (LC) method is developed, the pressure might be too high and close to the maximum pressure allowed by the hardware. It is important to address this issue before validating the method.
10/19/2023
Mass Spectrometers
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If user adds polarity switching to a MRM acquisition method that includes both negative and positive experiments, it is possible in theory to have a different signal intensity (usually lower). But having the appropriate settling time in the MRM method will prevent this in most cases.
10/19/2023
QTRAP Systems
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Triple Quad Systems
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What is matrix effect and how is it quantified? The loss of analyte signal due to presence of matrix in sample is called matrix effect in analytical chemistry. Here the quantitation of matrix effect is also explained.
10/19/2023
Mass Spectrometers
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Software
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How to Adjust LC Flow Rates after Changing a Column’s Inner Diameter (ID) If a user is following an existing liquid chromatography (LC) method but is using a column with an inner diameter (ID) that differs from the original method, how should the LC parameters change?
10/19/2023
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Name conflict error when creating a new quantitation method in MultiQuant™ software The error message, "The specified name conflicts with an analyte in another period/experiment" appears when making a new quantitation method in MultiQuant™ software. This error is the result of one or more analyte names in the current experiment being identical to one of the analyte names(s) in another experiment within the same processing method.
10/20/2023
MultiQuant Software
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Molecule Profiler software version 1.3 supports a dedicated workflow for antibody drug conjugates (ADCs). The entire antibody sequence can be copied into the software for processing.
10/20/2023
Academia Omics
|
SCIEX OS
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MetabolitePilot Software
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How To Report Out Regression Types in Reporter Template Suite 3.2 To report out the regression type used in a curve fit, a combination of IF, ELSEIF, and ELSE tags are required in the report template in Reporter Template Suite 3.2.
10/20/2023
SCIEX OS
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Analyst Software
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MultiQuant Software
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How does increasing column temperature affect LC methods? Increasing the column temperature can affect liquid chromatography (LC) parameters positively by decreasing column pressure, reducing retention times, and lowering the overall analysis time. Fluctuation in column temperature can result in unstable retention times and peak shapes.
10/20/2023
Mass Spectrometers
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Software
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The antibody drug conjugate (ADC) workflow in Molecular Profiler software 1.3 helps to identify and further characterize cytotoxic drugs, their breakdown products, and the linker connected to the entire antibody sequence. This article describes how to set up the processing parameters for the ADC workflow.
10/20/2023
Academia Omics
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Pharma CRO
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SCIEX OS
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MetabolitePilot Software
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Optimization Report (XPS File) in SCIEX OS Software Does Not Display Graphs After completing a multiple reaction monitoring (MRM) infusion in SCIEX OS software, the optimization report (.xps file) does not have any graphs displayed even though the graphs appeared in the software after the optimization was completed. This is due to a Windows update (update for Microsoft Windows KB5020866) that restricts .xps files.
10/20/2023
SCIEX OS
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What Are the Different Data File Types in Analyst® and SCIEX OS Software? In the data sub-project within a project folder in Analyst® or SCIEX OS Software, there can be a multitude of file types associated with one set of raw data. The file types and the software they are associated with are listed in this article.
10/20/2023
SCIEX OS
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Analyst Software
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How to generate reports in CSV format with SCIEX OS if no comma-separated report style is visible If no comma-separated report style is visible, you must change the extension of the TXT file to CSV when saving the file.
11/14/2023
SCIEX OS
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Shimadzu LC-40 systems troubleshooting tips and tricks The table shows the most common symptoms encountered for Shimadzu LC-40 systems and details possible causes with the appropriate corrective action. This HPLC system is commonly used with SCIEX mass spectrometers. Design changes in this model vs older Shimadzu models may require a different approach to troubleshooting your LC-MS system.
11/16/2023
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Signal Noise in Sciex OS Sofware - Analytics (Sciex OS 2.0 or Higher) This article shows how to select and apply signal to noise algorithms and how to use them
12/07/2023
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Cleaning of SelexION™ Cell and Electrodes This article describes different levels of cleaning the SelexION™ cell and electrodes
12/07/2023
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How to Avoid Corona Discharge in Electrospray Ionization (ESI) This article describes measures to avoid corona discharge
12/07/2023
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This article shows how to change the font size of text elements in Reporter templates
12/07/2023
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How to Add Additional Amino Acids into Molecule Profiler Custom Elements List This article demonstrates how to add additional amino acids into the custom elements list of Molecule Profiler
12/07/2023
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Where to find Signal-to-Noise in SCIEX OS Explore mode This article explains how you can manually evaluate the Signal-to-Noise within a chromatogram in the SCIEX OS Explore mode.
12/08/2023
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How To Perform A Master-Reset For PA800 Series 32 Karat Software and Pa800 Plus transport problems can occur due to faulty EEPROM values. These corrupt EEPROM values can be fixed with a Master-Reset
10/30/2023
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Finding the Number of Points Across a Peak in Sciex OS Software This article shows the possibilities to determine the amount of data points across a peak
12/06/2023
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Create fast optimization acquisition methods for Q0D mapping in SCIEX OS software With the Q0D mapping calculation sheet you can easily create acquisition methods for the optimization of Q0D values on column with matrix.
12/06/2023
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SelexION® and Selexion®+ - How to Avoid Discharge Error This article lists reasons for discharge error on SelexION® and Selexion®+ and how to avoid those
12/06/2023
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Where to find Signal-to-Noise in SCIEX OS Explore mode This article explains how you can manually evaluate the Signal-to-Noise within a chromatogram in the SCIEX OS Explore mode.
12/08/2023
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Where to find Signal-to-Noise in SCIEX OS Explore mode This article explains how you can manually evaluate the Signal-to-Noise within a chromatogram in the SCIEX OS Explore mode.
12/08/2023
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What Is the Part Number for the Solvent Guides Used in the Amplifex™ Diene Reagent Kit? This article provides the part number for the solvent guides used in the Amplifex™ Diene Reagent Kit.
11/06/2020
Amplifex Keto Reagent
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This article describes how to change the regional language settings within LibraryView™ and SCIEX OS Software. This prevents the license notification screen from popping up.
03/15/2024
SCIEX OS
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How can I change an audit map's settings in Analyst® software? To check a project and see how an audit map is applied or to change the settings for an audit map for a particular project in Analyst® software, navigate to the Audit Trail Manager. Select the Audit Trail Manager option under the View menu and the Audit Trail Manager window will open.
03/15/2024
Software
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MultiQuant™ MD software error: Missing active project folder Description on how an Analyst error causes MultiQuant™ companion software within Analyst® software to not function correctly.
03/15/2024
Analyst Software
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MultiQuant Software
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Creating a batch template in Analyst® software When submitting a batch in Analyst® software, it's convenient to use a template that be opened and modified to submit future batches without having to reenter sample, internal standard or known concentration information. To do create a batch template, open Analyst® software, activate a hardware profile, and then select Build Acquisition Batch in the vertical Navigation Bar.
03/15/2024
Software
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How is the FDR calculated in the peptide-spectrum matching step in the BioPharmaView™ software? This article describes how the false discovery rate (FDR) is calculated in BiopharmaView™ and BPV Flex software.
03/15/2024
Academia Omics
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Pharma CRO
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How to import a batch template into Analyst software Batch templates allow users to save time by applying information from a previous batch to a current batch of samples for queue submission in Analyst® software. Users will need to update any sample information that has changed prior to submitting the new sample information to the queue.
03/15/2024
Software
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If the percentage of the Percent Rule in the Peak Review Default Options has been changed, this can lead to an error message when a manual integration is executed.
01/31/2024
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This article provides information on the custom calculations required for processing data according to the guidance found in ICH guideline M10 – 3.2.4/3.3.2. The guidance requires that the accuracy of the back-calculated concentrations of each calibration standard should be within ±20% of the nominal concentration at the LLOQ and within ±15% at all the other levels. At least 75% of the calibration standards with a minimum of 6 calibration standard levels should meet the above criteria. These calculations were created to provide a ready-made solution for flagging problematic samples/components.
01/30/2024
Pharma CRO
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SCIEX OS
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Canned Calculation for ICH Guideline M10 – 3.2.1 Selectivity Available for SCIEX OS Software This article provides information on the custom calculations required for processing data according to the guidance found in ICH guideline M10 – 3.2.1. The guidance requires that it is demonstrated that no significant response attributable to interfering components is observed at the retention time(s) of the analyte or the IS in the blank samples. These calculations were created to provide a ready-made solution for flagging problematic samples/components.
01/30/2024
Pharma CRO
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SCIEX OS
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How to create a hardware profile in "read only" mode in Analyst® In Analyst®, if you use hardware profiles with AAO system it is recomended to put the hardware profile in "read only" mode to prevent file corruption issue.
01/12/2024
Analyst Software
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This article provides information on the custom calculations required for processing data according to the guidance found in ICH guideline M10 – 3.3.2. The guidance requires that at least 2/3 of the total QCs and at least 50% at each concentration level should be within ±15% of the nominal values and that the revised calibration range should cover at least 3 QC concentration levels (low, medium and high). These calculations were created to provide a ready-made solution for flagging outliers.
02/07/2024
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Canned Calculation for ICH Guideline M10 – 3.2.6 Carry Over Available for SCIEX OS Software This article provides information on the custom calculations required for processing data according to the guidance found in ICH guideline M10 – 3.2.6. The guidance requires that carry-over in the blank samples following the highest calibration standard should not be greater than 20% of the analyte response at the LLOQ and 5% of the response for the IS. These calculations were created to provide a ready-made solution for flagging in case of carry-over above the limit is detected.
02/07/2024
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How to export the Sample type in automatic reports generated by ChemoView™ The automatic reports that are generated by ChemoView™ are not capable of using all the tags that are also used by Analyst® software. The tag which allows to export the Sample type does not work. The procedure described in this article explains how to work around this issue.
02/12/2024
Analyst Software
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ChemoView Software
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By default, readbacks from a mass spectrometer are recorded in the MS Service log file. Use the MSServiceLog script to turn off the recording of the readbacks or to start recording the readbacks from the instrument in the MS Service log file. The MSServiceLog script is only applicable to the SCIEX 3500, 4500, 5500, 5500+, 6500, and 6500+ systems. The MSServiceLog script can be used without an active hardware profile but any changes made to the MS Service log settings take effect only after the hardware profile is reactivated.
02/15/2024
Academia Omics
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Clinical
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Environmental Industrial
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Food and Beverage
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Forensics
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Pharma CRO
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Mass Spectrometers
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Canned Calculation for ICH Guideline M10 – 3.2.2 Specificity Available for SCIEX OS Software This article provides information on the custom calculations required for processing data according to the guidance found in ICH guideline M10 – 3.2.2. The guidance requires that it is demonstrated that no significant response attributable to interfering components compared to the analyte or IS response in the blank and double blank samples, respectively, is observed. These calculations were created to provide a ready-made solution for determining which samples will need to be re-injected in pesticide reports.
02/15/2024
Pharma CRO
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SCIEX OS
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QTRAP Systems
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Triple Quad Systems
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QTOF Systems
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Why SCIEX OS does not create a .wiff file with certain configuration of acquisition mode ? During an acquisition, SCIEX OS always creates 3 types of "wiff" files : .wiff / .wiff.scan / .wiff2 which can then be used by SCIEX software to reprocess them. Analyst® and Multiquant® are compatible with .wiff files and .wiff.scan. SCIEX OS is compatible with .wiff, .wiff.scan and .wiff2 files. In certain particular configurations of acquisition mode there is no generation of a .wiff file, just a .wiff2 file. This article describes these particular configurations of acquisition mode.
04/10/2024
SCIEX OS
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Canned Calculation for SANTE Guideline 12830 2020 – Residual Plot Available for SCIEX OS Software This article provides information on the custom calculations required for processing data according to the guidance found in SANTE Guideline 12830 2020 – Residual Plot. The guidance recommends that the suitability of the chosen calibration function is demonstrated with a residual plot. These calculations were created to provide a ready-made solution for the visual inspection of the residuals and can be combined with a specific report.
01/30/2024
SCIEX OS
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Canned Calculation for SANTE Guideline 12682_2019-D2 bis - Available for SCIEX OS Software This article provides information on the custom calculations required for processing data according to the guidance found in SANTE 12682_2019 – D2 bis. The guidance requires that analyte retention times in the extracted pesticide samples should fit to that from the calibration standards. These calculations were created to provide a ready-made solution for flagging problematic samples/components.
01/31/2024
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How to perform Positive charging test using Sciex OS® on Blueline instruments How to perform Positive charging test using Sciex OS® on Blueline instruments
01/31/2024
Mass Spectrometers
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Canned Calculation for SANTE Guideline 12682_2019 - C18 Available for SCIEX OS Software This article provides information on the custom calculations required for processing data according to the guidance found in SANTE 12682_2019 - C18. The guidance section deals with the requirements to perform calibration by interpolation.
02/28/2024
SCIEX OS
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Canned Calculation for SANTE Guideline 12682_2019 - C15 Available for SCIEX OS Software This article provides information on the custom calculations required for processing data according to the guidance found in SANTE 12682_2019 - C15. The guidance requires that without a bracketing calibration the determination system has been shown to be free from significant drift, e.g. by monitoring the response of an internal standard. These calculations were created to provide a ready-made solution for evaluating a possible drift in the internal standard response.
01/30/2024
SCIEX OS
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Create fast optimization acquisition methods for Q0D mapping in SCIEX OS software With the Q0D mapping calculation sheet you can easily create acquisition methods for the optimization of Q0D values on column with matrix.
01/31/2024
SCIEX OS
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How to perform Positive charging test using Sciex OS® on 7500 instruments How to perform Positive charging test using Sciex OS® on 7500 instruments
02/02/2024
Mass Spectrometers
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How Can I Transfer an Acquisition Method from Analyst® to SCIEX OS Software? To transfer or import an acquisition method (*.dam file) created in Analyst® software into SCIEX OS software, open the MS Method tile and then select Convert File. Only the MS experiment will be imported into SCIEX OS software. The LC method from Analyst software will need to be entered manually.
06/06/2023
SCIEX OS
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Analyst Software
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How do I install MarkerView™ software 1.4 using the SCIEX OS software installer? The MarkerView™ software 1.4 is available within SCIEX OS software as an optional integrated software components and is now installed using the SCIEX OS software installer (version 3.1 and higher) rather than using a stand-alone software installer specific to MarkerView software.
04/19/2024
Software
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How to calibrate MS3 in negative mode in Analyst® software In PPG calibration there isn’t a solution to calibrate MS3 in negative mode. Moreover, there isn’t a solution to verify MS3 in negative mode (like Reserpine for MS3 in positive mode). Agilent Tuning Mix must be used to calibrate MS3 in positive mode and then “MS3 calibration” must be copied from positive mode to negative mode.
04/18/2024
QTRAP Systems
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Analyst Software
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What information should I send if the service package won't generate in SCIEX OS software? If the service package will not generate in SCIEX OS software, users can collect and send the needed logs manually. The information needed by the support team is listed in this article.
04/19/2024
Software
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Hardware profile errors on X500 QTOF system resolved with driver upgrade After upgrading SCIEX OS software on an X500 QTOF system and creating a new hardware profile, users may see an error message: "Connection to the device failed. Confirm the device settings. Need to do auto configuration before doing test device." To resolve this error, the xTDC4 driver needs to be updated on the acquisition PC (as described in the SCIEX OS installation guide.)
04/19/2024
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