Include PTM localisation scoring in ProteinPilot


Include some type of scoring in ProteinPilot (OK I'll say it - something like "Ascore"...) to discriminate the various possible PTM sites for each spectral match. Apparently SWATH data is actually a rich source of frequently sampled MS/MS spectral peaks, which could open the door to a superior way of discriminating the possibilities for PTM location - see recent paper below: https://www.biorxiv.org/content/early/2018/11/07/464545 So this might also be a route to explore, in addition to analysing typical IDA data.


0 Comments Jan 13, 2019 36 Views Product: ProteinPilot Software