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CESI-MS/MS: Quantitation of Highly Polar Pesticides

Concerns about the health effects caused by biogenic and anthropogenic interferents, along with the large amounts of pesticides that are used each year, are driving the need to better quantitate residues of highly polar pesticides.

Unfortunately, analysis with LC-MS/MS can suffer from matrix suppression, poor retention time stability, and limited by the lack of polar counterpart to the reversed phase multi-residue screens capable of testing for hundreds of compounds.

In this webinar, you will see how CESI-MS/MS has been highly effective for the analysis of charged pesticides including glyphosate, AMPA, glufosinate, fosetyl-Al, phosphonic and phosphoric acids, ethephon, paraquat, diquat, mepiquat, and chlormequat in tree nut matrices, all within a single run (vs 3 runs on different columns with LC-MS/MS).

Key Learning Objectives:

  • Discover how CESI-MS/MS has been highly effective for the analysis of charged pesticides all within a single run (vs 3 runs on different columns with LC-MS/MS)
  • Learn how the ultra-low flow rates associated with CESI greatly reduce matrix suppression to achieve high linear response over 2+ orders of magnitude

Who Should Attend:

  • Lab scientists or managers working on difficult LC-based separations
  • Those interested in polar pesticide analysis utilizing an orthogonal technique to LC/MS

Presenter

RUO-MKT-11-8784

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