A New Chiral MS Technology That Will Change Your Lab
September 10, 2015
Chiral separation of drug enantiomers is essential in order to differentiate the most active pharmacological agent from the less active one. In the case of forensic analysis, the presence of the active enantiomer in the specimen must also be unequivocally confirmed. This avoids potential legal arguments and simplifies challenges to the analytical findings.
This presentation highlights and demonstrates the advantages of CESI-MS chiral analysis using as an example the separation of enantiomers of methamphetamine and its metabolite amphetamine. Chiral separation and quantification resulted in excellent resolution and quantitative data.
Key Learning Points
Understand the need for chiral separation coupled with MS in drug screening
Learn how CESI-MS provides high sensitivity MS detection in drug screening samples with minimal ion suppression
Discover how chiral separation may be coupled with CESI-MS to provide ultra-high resolution and sensitivity drug screens
September 10, 2015 8:00 AM PT 11:00 AM ET 3:00 PM BT
John C. Hudson SCIEX Retired Royal Canadian Mounted Police Toxicologist 33yrs Forensic experience University of Regina, Regina, Canada