Comprehensive Cannabis Analysis: High linear dynamic range potency, terpenes, pesticides and aflatoxins from one extract using one column and one solvent system
Increased legalization of Cannabis for medical and adult use substantiates the need for standardized robust and reproducible methods for quantitation of pesticide residues, aflatoxins, relevant psychotropic cannabinoids, and terpene profiles in Cannabis products. The SCIEX vMethod system along with the highly sensitive Triple Quad/QTRAP® 6500+ system, can meet the demanding maximum residual levels (MRLs) for a suite of pesticides and aflatoxins in Cannabis flower matrix using a simple solvent extract with no cleanup. Cannabis flower demonstrated the most severe matrix-induced ion suppression on our target analytes and, therefore, the performance of this method in flower represents performance in the most difficult matrix. A 16-minute gradient maximizes separation of endogenous isobaric interferences.
Key Learning Points:
Leveraging instrument sensitivity to simplify extraction protocols
Using Atmospheric Pressure Chemical Ionization (APCI) to analyze additional compound classes across a wider concentration range
Employing a simple algorithm to extend the linear dynamic range of your analysis
Presenter: Robert Di Lorenzo
Application Support Scientist, SCIEX
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