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Overcoming the Challenges of Quantifying Highly Polar Amines

Environmental and Agricultural Applications of CESI-MS

Highly polar natural products and environmental toxicants, such as amines are subject to N-nitrosation, a structural modification that is not chromatographically distinct, at least with conventional approaches, and often is spectrometrically masked, such as during electron-impact ionization.

In this webinar, Dr. Spencer Walse illustrates how CESI-MS/MS has revolutionized the spectrometric quantification of amines, formerly prone to matrix suppression and chromatographic complications associated with reversed phase and ion exchange techniques.

Key Learning Objectives:

  • Understand the challenges of quantifying amines
  • Learn how to successfully quantify highly polar natural products and environmental toxicants
  • Discover how orthogonal separation technologies like CESI can help you see what you’ve been missing from other chromatographic techniques

Who Should Attend:

  • Lab scientists or managers working on difficult LC-based separations
  • Those interested in food, pesticide, and environmental analysis utilizing an orthogonal technique to LC/MS



Watch On-Demand