As regulatory expectations around per- and polyfluoroalkyl substances (PFAS) continue to evolve, pharmaceutical laboratories are under increasing pressure to detect and quantify PFAS at ultra-trace levels across complex sample matrices.
Join this live webinar to explore analytical approaches for sensitive, selective, and reproducible PFAS analysis in pharmaceutical applications.
Drawing on representative workflows and quantitative performance data, this session will highlight strategies for PFAS monitoring in active pharmaceutical ingredients (APIs) and pharmaceutical packaging materials using the SCIEX 7500+ system.
Attendees will gain insight into method development considerations, contamination control strategies, chromatographic separation approaches, and quantitative performance for broad PFAS panels in pharmaceutical workflows.
What you will learn
- Key analytical challenges associated with PFAS monitoring in pharmaceutical workflows, including contamination control and complex sample matrices
- Approaches for sensitive and selective PFAS quantitation in APIs and pharmaceutical packaging materials using LC-MS/MS
- Chromatographic and workflow strategies to improve PFAS separation, reproducibility, and quantitative confidence
- Quantitative performance results, including LOQs as low as 0.005 ng/mL, broad linear dynamic range, and recovery performance across multi-compound PFAS panels
Speaker
Dr. Cathy Lane
Joined SCIEX in 2006 as a Support Specialist and in 2021 took up the role of EMEAI Applications Lead for Pharma & Peptide Quant.
She has more than 20 years’ experience in the development of LC/MS methods across multiple application areas, and specializes in workflows for peptide quantification.
She obtained her PhD in mass spectrometry-based proteomics from the University of London School of Pharmacy in 2004