Knowledge Base Article

How can I change an audit map's settings in Analyst® software?

To check a project and see how an audit map is applied or to change the settings for an audit map for a particular project in Analyst® software, navigate to the Audit Trail Manager. Select the Audit Trail Manager option under the View menu and the Audit Trail Manager window will open.

Creating a batch template in Analyst® software

When submitting a batch in Analyst® software, it's convenient to use a template that be opened and modified to submit future batches without having to reenter sample, internal standard or known concentration information. To do create a batch template, open Analyst® software, activate a hardware profile, and then select Build Acquisition Batch in the vertical Navigation Bar.

How to import a batch template into Analyst software

Batch templates allow users to save time by applying information from a previous batch to a current batch of samples for queue submission in Analyst® software. Users will need to update any sample information that has changed prior to submitting the new sample information to the queue.

How does increasing column temperature affect LC methods?

Increasing the column temperature can affect liquid chromatography (LC) parameters positively by decreasing column pressure, reducing retention times, and lowering the overall analysis time. Fluctuation in column temperature can result in unstable retention times and peak shapes.

What is matrix effect and how is it quantified?

The loss of analyte signal due to presence of matrix in sample is called matrix effect in analytical chemistry. Here the quantitation of matrix effect is also explained.

Recommendations for lower and upper temperatures for an Exion 2.0 method in Analyst® software

When working with an acquisition method that uses an Exion 2.0 LC system in Analyst® software, the lower and upper temperature settings should be set slightly higher or slightly lower, respectively, than the safety limits to prevent column oven errors.

Can a different user log into Analyst® software set to integrated or single user mode?

No, opening the Analyst® software as a different user when the security configuration is set to integrated mode or single user mode is not supported.

The Metabolomics Workflow in OneOmics™ Suite 3.4 Offers a New NIST Library Search

The OneOmics™ suite 3.4 offers a new feature in its metabolomics workflow where the NIST library can be selected as a library option in the Merge workflow.

Upgrading the Biologics Explorer software

General steps for the upgrade process for the Biologics Explorer (BE) software are described in the release notes. Versions of SCIEX OS software 3.1.5 and greater, have an embedded BE software tile. For those versions of SCIEX OS software containing the BE tile, the SCIEX OS software must first be closed, and all SCIEX OS services stopped before proceeding with the BE software upgrade.

Will my old workflow templates or data be lost when upgrading Biologics Explorer software?

The Biologics Explorer software will automatically save all workflow templates and data from previously installed versions.

Enabling ChemSpider funtionality in SCIEX OS software

To enable the ChemSpider feature within SCIEX OS software, the ChemSpider add-on license must be added to the SCIEX OS software program files and the Formula Finder feature must be enabled in the processing method.

How Do I Work with LC Devices Not Directly Controlled by SCIEX OS Software?

To synchronize signals between a SCIEX mass spectrometer, the SCIEX OS software and LC devices that are not directly controlled by the SCIEX OS software, contact closure can be used.

DIP Switch Positions when Connecting Agilent LC Systems to SCIEX Mass Spectrometers

When connecting Agilent LC Systems to a SCIEX mass spectrometer, the dual-in line packet (DIP) switches on the Agilent LC systems should be in the down (off) position, except for switches 7 and 8 which must be in the up position for the pump and detector.

How To Install the DIA-NN Software 1.8.1 To Process SCIEX WIFF Files?

To process SCIEX data files (.wiff) with the DIA-NN software, the DIA-NN software must be installed using the downloaded executable file. In addition to installing DIA-NN software, the ProteoWizard software must be installed and the dll files in the ProteoWizard installer folder named Clearcore and SCIEX must be transferred to the DIA-NN installer folder.

What Is a DIA-NN Library-Free Search in a Data-Independent Acquisition (DIA) Proteomics Workflow on ZenoTOF 7600 System?

A library-free search, or direct-DIA (data-independent acquisition), is a proteomics strategy to identify unknown proteins and peptides by generating a theoretical spectral library from a FASTA file and then searching the DIA data against this spectral library using the DIA-NN software.

Which Molecule Profiler Software Version Can Process EAD Fragmentation Data?

The Molecular Profiler software 1.3 is embedded in the SCIEX OS software version 3.1.6 and can assign structures by using fragments from both electron-activated dissociation (EAD) and collision-induced dissociation (CID) techniques.

How Do I Select a Compound Database in DiscoveryQuant™ Software?

To select a compound database in DiscoveryQuant™ software, select the Data menu, and then select Database Selection. The Compound Database Selection dialog will open, and the database options are indicated in this window.

What Are the Minimum Cycles Needed To Obtain Quality Optimizations in DiscoveryQuant™ Software?

When setting up an optimization experiment in DiscoveryQuant™ software, the minimum number of cycles needed to obtain quality optimizations is two.

How Are Entries Added to the Compound Database in DiscoveryQuant™ Software?

To add entries to the compound database in DiscoveryQuant™ software, the Edit Compound Workspace must be opened.

What Is the Username and Password for the Empty Compound Database in DiscoveryQuant™ Software?

To open the empty compound database - CompoundDB3.mdb - for DiscoveryQuant™ software, a username and password are required. The username is Admin and the password is !DQO2.

How Is the Analyst Response Factor Column Generated in SCIEX OS Software?

In the SCIEX OS Analytics workspace, Response Factor is not one of the standard columns that users can select from the results table, but it can be created and added to the results table by adding a custom column. 

Why Can't I Print My Audit Trail Record from Analyst® Software?

For Windows 10 operating systems, if the user who logs on to the Analyst® software in mixed mode is different than the user who logged on to the computer, then the audit trail record printing function will not be available.

How Can I Customize the Project Information in DiscoveryQuant™ Software?

To customize the project information in DiscoveryQuant™ software, open the Setup Optimization workspace.

Do Analyst® Software and Analyst Administrator Console (AAC) Support Cross-Domain Logins?

No, the Analyst® software and the Analyst Administrator Console (AAC) do not support cross-domain logins. The computer where Analyst software is installed, the AAC computer, and the network users should be on the same network domain.

Can I Create an API Instrument Project in a Shared Drive for Network Acquisition with Analyst® Software?

No, when using Analyst® software for network acquisition, users should not create a project with the name API Instrument in the network root directory. Doing so causes the instrument audit trail events to be recorded in the API Instrument project on the network instead of in the local API Instrument project.

Getting Started with OneOmics™ Suite 3.4

This article describes the required registration, browser setup, software setup, and first steps for uploading data to the Data Store in the web-based and cloud-powered OneOmics™ suite.

Can I Install SCIEX OS and Analyst® Software on the Same Computer for Data Acquisition?

Analyst® software and SCIEX OS software can be installed on the same PC, but SCIEX does not support workflows that use both the Analyst and SCIEX OS software to acquire data from the same mass spectrometer.

Can the Installation Repair Tool in SCIEX OS Software Be Used for a Central Administrator Console (CAC) Software Install?

No, the Installation Repair Tool in SCIEX OS software can not be used to assess the installation of the Central Administrator Console (CAC) software.

What Are the New Visualization Features in the OneOmics Suite for DIA-NN Software Output Files?

The DIA Results app, a new software feature in the cloud-based OneOmics suite for processing DIA-NN software output (TSV file), helps visualize proteomics data so that protein quantification results can be interpreted in the Analytics and Browser sections.

What Is the Maximum Length of Characters for the Path to the Installation Folder for SCIEX OS Software?

Please ensure that the path to the installation folder for SCIEX OS software is 118 characters or less. If it is longer, the installation of SCIEX OS software will not proceed.

Setting Up the LC Pressure Trace Monitoring for an Acquisition Method in Analyst® Software

Setting up the LC pump pressure trace and column oven temperature trace monitoring supported by Analyst® software 1.7.3 is explained here. The resulting pressure traces can be stored in the data file for each sample. 

Two New Tiles in the OneOmics™ Suite Support Data Processing with DIA-NN Software

The two new software tiles in the OneOmics™ suite are the Ion Library app and the DIA Results app. These apps are used to process data-independent acquisition (DIA) data acquired by the ZenoTOF 7600 system, along with the DIA-NN software module that is embedded in the OneOmics suite.

How Do I Start the Installation Confirmation Tool in SCIEX OS Software?

SCIEX OS 3.1 software has an installation confirmation tool that ensures that the software has been installed correctly. The confirmation tool can be started by tapping or clicking Search on the taskbar and then typing "SCIEX OS Installation Confirmation Tool" in the search box.

What File Format Can Be Used for RNA Data Sets in the OneOmics™ Suite 3.4?

To import RNA data sets into the OneOmics™ suite, the RNA data sets need to be in the Cuffdiff output file format from CuffLinks.

Creating an Ion Library for DIA-NN Software Using the Ion Library Generator in OneOmics™ Suite 3.3

This article describes how to create an ion library for DIA-NN in the OneOmics™ suite 3.3 using the Ion Library Generator.

What Are the New Features in the ProteinPilot™ Software Found in the OneOmics™ Suite 3.3?

This article describes the new software features recently implemented in ProteinPilot™ software 5.0.3 in the OneOmics™ suite version 3.3. The version of ProteinPilot software found in the OneOmics suite has nearly the same features as the desktop version of ProteinPilot software.

Microsoft Office 365 Cannot Be Activated on SCIEX Acquisition PCs

Because of the version of Microsoft Windows that is installed, Microsoft Office 365 may not be able to be activated on certain SCIEX acquisition PCs.

How To Install Templates in Biologics Explorer Software

This article describes how to install the template packages in Biologics Explorer software.

Can the SCIEX OS Software Central Administrator Console (CAC) Run on a Citrix Server?

The SCIEX OS Software Central Administrator Console (CAC) should run on a Citrix Server, but this configuration has not been tested and is not officially supported.

How Many Client Workstations with SCIEX OS Software Does the Central Administrator Console (CAC) Software Support?

The Central Admin Console (CAC) software can support 100 client workstations with the SCIEX OS software installed.

Fatal Error in MultiQuant™ Software: The File or Directory Is Corrupted and Unreadable

While opening a file or creating a results table in MultiQuant™ software, users may receive the error message "The file directory is corrupted and unreadable." Running the Windows file explorer drive check can resolve this issue.

How Can I Get a Biologics Explorer Trial License?

To obtain a Biologics Explorer (BE) 1.x trial license, send an email to biologics.explorer.orders@sciex.com with a request for a 30-day trial.

Analyst® Software Error: Please Enter Positive Numeric Value Only

While attempting to select manual tune mode, users of Analyst® software may see the error message "Please enter positive numeric value only." This error results from commas instead of periods being used as decimal points in non-English based operating systems.

Can Results Tables Created in MultiQuant™ Software Be Opened in SCIEX OS Software?

It is not possible to open a results table (.qsession file) that was generated in MultiQuant™ software in SCIEX OS software.

Transferring Acquisition Methods Between Analyst® Software and Analyst MD Software

Is it possible to move an acquisition method that was created in Analyst® software to Analyst MD software?

How Do I Convert Acquisition Methods Created in Analyst® Software for Use in SCIEX OS Software?

Users can convert existing acquisition methods created in Analyst® software for use in SCIEX OS software by using the Convert File option in the Open menu in the MS Method tile. Only the MS portion of the method will be converted; there is no conversion function for the LC portion of the method.

How Do I Find the Build Number for Analyst® Software Version 1.7.3?

With Analyst® software version 1.7.3, the build number no longer appears in the About Box due to a new requirement that the displayed information in Analyst 1.7.3 had to be in sync with the MD version of the software. Users can check the version (build) number by navigating to the Programs and Features section of the control panel by using the Details view to see the version for each installed software.

Unable to Install MultiQuant™ Software 3.0.3 on Windows 10 Version 20H2

MultiQuant™ software 3.0.3 is not compatible with and cannot be installed on Windows 10 version 20H2. In order to install MultiQuant software 3.0.3, Windows 10 must be downgraded to an earlier version.

Can Analyst® and SCIEX OS Software be Installed on Separate Computers and then Used Alternately for Acquisition?

Switching between Analyst® and SCIEX OS software for acquisition, either on the same or different computers, is not a supported workflow.

Can Both Analyst® Software and SCIEX OS Software be Used for Acquisition on the Same PC?

No, Analyst® and SCIEX OS software cannot be used for acquisition on the same computer. Analyst software will be removed from an acquisition PC if it is upgraded to use SCIEX OS software for acquiring data.

Are Validation Services Available To Install and Test the SCIEX OS Software in My Lab?

Yes, the SCIEX validation services team has helpful and cost-effective services for SCIEX OS software validation.

Can Audit Maps Be Easily Transferred from Analyst® Software to SCIEX OS Software?

No, audit maps cannot be directly transferred from Analyst® to SCIEX OS software.

Are There Differences in LIMS Column Headers between Analyst® and SCIEX OS Software?

As users switch from Analyst® to SCIEX OS software, there may be concerns about column header or formatting differences between the two software versions when importing or exporting information using a LIMS. Although similar, there are format and column differences between the SCIEX OS and Analyst software systems, and SCIEX can provide examples for both formats.

Is the SelexION® Device Compatible for Acquisition with SCIEX OS Software?

No, the SelexION® device is not yet supported in SCIEX OS software.

Do I Need To Revalidate My Software Workflow after Upgrading from Analyst® to SCIEX OS Software?

Yes, the software workflow will need to be revalidated after upgrading from Analyst® to SCIEX OS software. SCIEX OS software is a completely different software platform than Analyst software, and because even minor changes require revalidation, the switch from Analyst to SCIEX OS software will also require a revalidation.

Does the SCIEX 7500 System with SCIEX OS Software Work with StatusScope® Remote Monitoring Service?

Yes, the SCIEX 7500 System with SCIEX OS Software is compatible with StatusScope® remote monitoring service version 2.0.

Locating the Computer ID(s) on a PC with a Windows Operating System

The computer ID, also known as the physical or MAC address, is a number used when activating a software license on Sciex.com and contains a series of 12 characters followed by a space and then another 12 characters. This article explains a few different ways to generate the computer ID on a Windows 10 system. (These same steps apply to a Windows 7 system as well.)

How to Save Application and System Event Logs in Windows 10

The Windows event logs often contain crucial data about the performance of SCIEX software. Follow these steps in Analyst® software to save your system and application event logs so that they can be analyzed by the SCIEX support team.

What is the Maximum Sampling Speed of the Echo® MS System?

There are two modes for the Echo® MS system, normal and fast. The normal mode maximum sampling speed is 1 sample/s. In fast mode, the maximum sampling speed is 3 samples/s.

Setting Up Email Notifications and Emailed Reports in Cliquid® Software

To set up email notifications in Cliquid® software, launch the software and select the User Profile option. To start email notifications and the option to have reports emailed, the user's email address will need to be entered in the user profile.

What Sample Plate Formats Are Supported on the Echo® MS System?

The Echo® MS System is only compatible with specialized, acoustically clear microplates that were specifically designed to ensure the optimal and repeatable performance of droplet ejection. These specialized plates are available in both 384- and 1536-well formats.

Can a Method Built in MPX™ Software Be Converted to a Method Used with SCIEX OS Software?

No, methods built in MPX™ software cannot be converted for use in SCIEX OS software. Files built in MPX software are not supported in SCIEX OS software.

Is It Possible To Convert an Acquisition Method Built in Analyst® Software to a MS Method for SCIEX OS Software?

A MS acquisition method built in Analyst® software cannot be opened directly in SCIEX OS software 2.2, but it can be converted to a usable MS method in SCIEX OS software using the Convert file feature in the MS Method workspace.

Changing the Comparison Sample Assignment in Analytics in SCIEX OS Software

When reviewing a results table in the Analytics workspace of SCIEX OS software, users can change the comparison sample assignment from the one that was originally included in the processing method by selecting the option, Use the selected sample as the comparison sample.

What Are the Specifications for Installing SCIEX OS Software 2.2 on an Acquisition PC?

To install SCIEX OS software version 2.2 on an acquisition workstation, the PC needs to meet specific requirements. The following PCs are supported: 1) SCIEX workstation or workstation+ and 2) SCIEX Alpha workstation 2020.

Is the Database for DiscoveryQuant™ Software Limited to 1 GB?

Yes, the size of the Microsoft Access database file is limited to 2 GB. However, the reliability of the database degrades before reaching the 2 GB limit, so it is suggested that DiscoveryQuant™ software users create a new database before the database exceeds 1 GB.

Can a Processing Method Built in ChemoView™ Software Be Converted for Use in SCIEX OS Software?

No, a processing method built in ChemoView™ software cannot be converted for use in SCIEX OS software. Files built in ChemoView software are not supported in SCIEX OS software.

Can a Method Built in Cliquid® Software Be Converted to a Method for SCIEX OS Software?

No, methods built in Cliquid® software cannot be converted for use in SCIEX OS software. Cliquid software method files are not supported in SCIEX OS software.

Is Watson LIMS Software 7.6.1 SP1 Compatible with Analyst® Software 1.7.2 on Windows 10?

Yes, Watson LIMS software 7.6.1 SP1 is compatible with Analyst® software 1.7.2 on Windows 10. Please run as administer when installing both the Watson and the Analyst software to ensure LIMS integration between the two.

Enabling and Disabling the Data File Checksum Feature in SCIEX OS Software

To enable or disable the data file checksum feature in SCIEX OS software, navigate to the Configuration workspace in SCIEX OS software. Under the Projects tab under Data File Security, select the checkbox for Enable checksum writing for wiff data creation.

Where Are the SCIEX OS Software Project Audit Trail Archives Stored?

The audit trail records for a SCIEX OS software project are stored in the Audit Data sub-folder for the project. The audit trail file name is ProjectAuditEvents.atds.

When Does SCIEX OS Sofware Start Archiving Audit Trail Records?

In SCIEX OS software, the audit trail will be archived when it reaches 20,000 records.

Should I Revalidate My Software?

Periodic reviews of validated systems must be performed to ensure that no changes have been made that affect the validated state of the system. If there is a change, then the software needs to be revalidated.

What Do SCIEX Validation Services Include?

SCIEX qualification services include testing and documentation that demonstrates that the instrument is operating correctly and includes objective evidence showing what was tested, the specification for each test, and the results.

Will Software Validation Ensure that Our Lab Is 21CFRpart11 Compliant?

The SCIEX software validation service ensures that Analyst® software is configured correctly, that the necessary procedures are documented, and that objective evidence of these activities is provided to ensure 21CFRpart11 compliance.

My Annual SCIEX License Suddenly Stopped Working Before It Expired, Why?

A new annual SCIEX subscription license stopped working suddenly despite having many months of use remaining.

Can SCIEX OS Software Be Installed on a PC with Windows 10 Hotfix2?

No, SCIEX OS software cannot be installed on a PC with Windows 10 hotfix2.

Why Does the SCIEX OS Software 2.1.6 Installer Disable the System Restore Task?

The SCIEX OS software 2.1.6 installer disables the System Restore task for better performance of the application.

Can I Do Any Data Processing in Keystone™ Viewer Software?

No, Keystone™ viewer software provides data viewing capabilities only.

What SCIEX Mass Spectrometer Data Files Work with Keystone Converter Software?

Keystone Converter Software can convert nominal mass (.wiff1) files, but it does not work with SCIEX OS software files or TripleTOF system files.

Will Keystone™ Viewer Software Open Any AnIML file, or Just ANIML files Converted by Keystone Converter Software?

Keystone™ viewer software displays an AnIML file, including those that were not created by Keystone converter software.

How Does the Size of a Converted AnIML File Compare to the Original Wiff File Size?

The converted AnIML file created using the Keystone™ converter software is 1.6 to 1.8 times bigger for data sets with multiple reaction monitoring (MRM) data. This is because the original .wiff.scan file is compressed, but then it is uncompressed as part of the conversion and storage process when creating the AnIML file.

Is There a "Batch-Convert" Function Available in Keystone™ Converter Software?

Yes, Keystone™ converter software offers a command line option to allow for the creation of automated processes for converting large pools of legacy data.

What Information Is in the AnIML File Created by the Keystone™ Converter Software?

AnIML, an open standard XML data format for storage and sharing of experimental data, is the file format that is created when a data file is converted by the Keystone™ converter software. This article details the information that is included in the converted AnIML file.

How Are Peptides Named in BPV Flex Software after in Silico Digestion?

The general rule for naming peptides in BPV Flex software is: the first peptide resulting from a proteolytic cleavage is named T1 for sequences displayed from the N-terminus to the C-terminus; moving toward the C-terminus, the second proteolytic cleaved peptide is named T2, and so forth.

How to Improve SCIEX OS Software Performance during Data Analysis

SCIEX OS software may perform slowly during data analysis due to the location of the data files being processed. Relocating data files from a temporary location (such as the Windows desktop) to a SCIEX OS or Analyst software project folder that is located in the root directory mapped in the Configuration module of SCIEX OS software may improve the software performance. 

How to Change the Font in a Report Template?

Use these instructions to change the font of the text appearing in a report.

Locating the Name of a Server or PC Using the Command Prompt Window

This article describes the DOS commands used to access the name of the server or PC.

Locating the Name of a Server or PC Using the Command Prompt Window

This article describes the DOS commands used to access the name of the server or PC.

Obtaining Intensity Information from an IDA-EPI MS/MS Spectra

To obtain the intensity information from an IDA-EPI MS/MS spectra, the ProteoWizard data conversion tool, MSConvert, can convert SCIEX data files (.wiff and .wiff.scan) to other formats using MSConvert besides mzML, such as MGF or txt formats. These non-mzML formats create larger files but provide the spectral data in simple mass/intensity text.

What Is the Correct Format for the Client License Text for Software Using a Concurrent License?

To create and set up the license on the client PC for software using concurrent license server, the license text should be formatted as follows: SERVER [SERVERNAME.DOMAIN.COM or IP ADDRESS] ANY [PORT NUMBER] VENDOR ScxMSSW0 USE_SERVER

Checking for Administrator Rights on a Windows 10 PC before Installing Analyst®/SCIEX OS software

There are three simple steps to determine which Windows users are listed as administrators before installing SCIEX software.

How Do I Create a Dump File?

A SCIEX technical support agent may ask you to create and send a dump file to provide a snapshot of a SCIEX software application's processes, loaded modules and memory at a certain time point. This article explains how a dump file is created.

How To Generate a List of All Installed Programs and Windows Updates

To generate a list of all programs installed on a PC and a list of Windows updates, select the Programs and Features icon in the control panel. A list of all installed Windows updates can be created from the View Installed Updates screen.

Upgrading SCIEX Software Licenses

How to upgrade self-upgrade registered software licenses

General Guidance for Antivirus and Backup Software Used on Acquisition PCs

The antivirus or backup software on Analyst® software acquisition workstations should be configured in a manner that will disable real-time scanning and archiving of files in the Analyst Data folder.

What Parameters in ProteoWizard Are Needed when Converting .wiff2 Files to mzXML Files?

The parameter settings, including the PeakPicking value, that are used for converting .wiff2 files to mzXML or mzML files in ProteoWizard, are explained in more detail here.

Reporter 3.2: How To Report Calculated Concentrations of "<0" or "N/A"

If a MultiQuant™ or Analyst® software results table contains values of "<0" and "N/A" for some calculated concentration values, these text values must be converted to a numerical zero value first using an Excel query. These calculated concentration values cannot be filtered into a Reporter Template Suite 3.2 results template using an if statement that selects for calculated concentration values that are less than or equal to zero.

Does My Acquisition PC Have a Bad Ethernet Card?

This article summarizes some issues that might contribute to a bad network card.

What Is the Format of a LIMS Template?

A LIMS template is used to transfer data from a MultiQuant™ software results table to a LIMS system. The LIMS template is a comma delimited file with the fields to be output listed across the top of the report. Each field in the template should be separated by a comma.

Can Google Drive Be Used for Transferring or Storing Data Generated by SCIEX Software?

The use of Google Drive for data storage has not been tested with data sets generated on SCIEX software. Transferring and storing data using Google Drive has led to issues with data sets for some end-users because of a potential embedded encryption process in Google Drive.

Verifying if .NET Framework 3.5.1 Is Installed on a Windows 7 Operating System

To verify if .NET Framework 3.5.1 is installed on a PC running a Windows 7 operating system, the .NET Framework Verification Tool may need to be deownprogram in the link provided.

Changing the Number of Decimals Displayed in Analyst® Software Calibration and Metric Plots

This is a set of instructions for changing the number of decimals displayed in Analyst® software quantitation metric plots and calibration curves. The default number of decimals leaves the significance so low that you can not reproduce the results shown in the results table. A warning is given to let customers know that Regedit is a dangerous utility.

How To Move SCIEX Software License to a Different Computer

Description of the steps required to move an already activated SCIEX Software License from one computer to another.

How Do I Activate My SCIEX License Key?

To activate a SCIEX license key, log into www.sciex.com with your username and password. Navigate to https://sciex.com/support/activate-software and complete the required fields.

SCIEX Software Activation with Offline Workstation

How to activate Analyst, MultiQuant or SCIEX OS software with a computer which is not connected to the internet

SCIEX Software Activation with Online Workstation

How to activate Analyst, MultiQuant or SCIEX OS software with a computer which is connected to the Internet

Exporting ProteinPilot™ Software Data to PRIDE (PRoteomics IDEntifications)

Exporting ProteinPilot™ software data to the PRoteomics IDEntifications (PRIDE) database requires the .group files be converted to XML files. ProteomeXchange fully supports both MS/MS proteomics and SRM data submissions. Other types of proteomics data, including ProteinPilot data, is also possible using the partial submission mechanism.

How Can I Find the Computer ID on a Win 7 Operating System?

To locate the computer IDs (MAC or physical addresses) on a computer with a Windows 7 operating system, run the DOS command ipconfig/all, and a list of physical addresses be provided.

Permanent License Gives an Error Message of Expired for DiscoveryQuant™ Software

After launching DiscoveryQuant™ software, an error message is received indicating the software has expired even though a permanent license is installed.

Upgrading Analyst® Software Requires that Cliquid® Software be Uninstalled

Upgrading Analyst® software on workstations where Cliquid® software is also installed requires that Analyst be uninstalled as well as Cliquid software. After reinstalling Analyst software, then Cliquid can be reinstalled.

Where Are Report Templates Located for MasterView™ Software?

Report templates for MasterView™ software are located under the following root directory: C:\Users\Public\Documents\AB SCIEX\MasterView\Templates

Where Are the Queries Used with MultiQuant™ Software Stored?

MultiQuant™ software queries are saved in the following folder: C:\ProgramData\AB SCIEX\MultiQuant\Queries.

SCIEX Trial License Key Not Received

The email address associated with your Sciex login must be verified when you request a trial license, otherwise you will not receive your trial license key by email.

Activating a SCIEX Software Trial on Workstations that do not have Internet Connection

Activating SCIEX software on a computer without internet access can be made simpler by following these steps

Convertingt MS data from .Wiff Format to a .Mgf File

To use different search engines/software, .wiff data must be converted to different format such as .mgf file before being able to submit the data for a search.

SCIEX Registered Software Webpage Lists All Recently Activated Licenses

The SCIEX Registered Software webpage (https://sciex.com/support/registered-software) lists all recently activated licenses.

Access to Path Is Denied Error when Installing License

When installing a Sciex software license, an error message appears that says the license was not sucessfully installed and the access to the path C:\Program Files\AB Sciex\.... is denied. This error message indicates that 1) the user doesn't have sufficient privileges to access the Program Files, or 2) the license file needs to be placed in correct location in the Program FIles manually.

Downloading Software from the SCIEX Website Requires the Most Current Browser

To successfully download a trial license or software from the SCIEX website, your browser needs to be up-to-date.

Where Can I Download SCIEX Software?

Full versions of many our software programs can be downloaded from the SCIEX website at https://sciex.com/software-support/software-downloads.

Selecting a New Tab in the Waters Method Editor Resolves LC Method Creation Error in Analyst® Software

An error results when selecting the ACQ-BSM tab when creating an LC method using the Acquity Method Editor accessed through Analyst® software. It can be resolved by selecting any other tab in the method editor screen.

How to Generate MRM Ratios in Analyst Software

This is a known issue in the ProteinPilot™ software 5.0.2 and was resolved with a patch.

Replacing a Trial License with a Permanent License

When opening a program, an error message may appear that indicates that the license has expired, even when a permanent license is thought to be installed. For these cases, the trial license may still be installed in program files and will need to be removed and replaced with the permanent license.

Will SCIEX Have a Windows 10 Compatible Analyst® and Mutiquant™ Software Version?

Analyst 1.7 software and Multiquant 3.0.3 software are now available, and both of these versions are Windows 10 compatible.

Importing *.xlsx Files to Build Batches in Analyst® Software

Importing *.xlsx files to build batches in Analyst® software requires Microsoft Office 32-bit to be installed, although its not recommended to use the 32-bit version of Office on a 64-bit Win 7 operating system. SCIEX recommends that the following file formats be used instead: .xls, .csv and .txt.

Acquity AAO Service Did Not Start

Steps are provided for editing the service properties of the AAO file to resolve the error "Cannot start service from the command line or a debugger." Editing the service properties will direct the AAO file to reopen in the event that it closes.

Where can I download MaxQuant software?

MaxQuant software is a quantitative proteomics software package designed for analyzing large-scale mass-spectrometric data sets. It supports all main labeling techniques like SILAC, di-methyl, TMT and iTRAQ, as well as label-free quantification.

Reasons for Data File Processing Failure with the Data Converter Version 1.3 Beta

What are the potential issues listed which can cause the SCIEX MS data converter version 1.3 beta to not work correctly?

How Is the Software Protection Service in Windows 7 Disabled?

The steps for disabling the Software Protection service in Windows 7 are provided here.

MultiQuant™ Software Would Not Launch after License Installation

MultiQuant™ software may not launch after installation, and a -1 license installation error may appear. To resolve this issue, the user needs to be logged into Windows as an administrator and have full access to the program files on the C: drive.

How Do I Obtain a Trial License for SCIEX Software?

To download and obtain a licensed trial for a SCIEX companion software, navigate to https://sciex.com/products/software#tryfree and select the software that you would like to try.

Where Can I Find Out If My Software Upgrade Is Free or a Paid Upgrade?

To determine if your software upgrade is complimentary, check the SCIEX webpage, Software Product Lifecycle at https://sciex.com/software-support/software-support-policy.

Should I Install Windows Updates on My Acquisition Computer?

Windows updates should not install automatically on your acquisition workstation, but once you receive notification that there are new updates, these can be installed when Analyst® software is not acquiring data.

Installing and Activating a New License for a Computer not Connected to the Internet

If a software license needs to be installed on a computer that is not connected to the internet, look up the computer IDs for that computer, copy them, and then activate the license on an internet-connected workstation.

How Are Simple Queries Created in MultiQuant™ Software?

Simple queries can be created in MultiQuant™ software by selecting the Create Simple Query option in the Process menu. The formula can then be entered into the Create Query File screen.

How to Save Application and System event logs in Windows 7

The Windows event logs often contain crucial data about the performance of SCIEX software. Follow these steps to save your system and Application event logs so that they can be analysed by the SCIEX support team.

Where Can I Find More Information about Software IQ/OQ Testing Plans?

More information about software validation services can be found by emailing complianceservices@sciex.com.

How Can Concentrations above the ULOQ be Flagged in MultiQuant™ Software?

Concentrations above the ULOQ can be flagged in your MultiQuant™ software results table by setting up the Upper Limit of Calculated Concentration in the Quant method.

How Can I Recover My Software License after Replacing My Hard Drive?

If your computer hard drive dies and you need to recover your license files, please contact SCIEX technical support for assistance.

Can You Print a Quantitation Method in MultiQuant™ Software?

MultiQuant™ software does not have an option to print the quantiation method. However, the quantitation method can be copied or exported as text file into Excel and printed.

How Can the Data from Two Experiments Acquired within One Period Be Separated in Analyst Software?

Data from two or more experiments acquired within one period can be separated by opening a data file in Explore mode and double clicking the green arrow.

How Are the Correct Solenoid Valves for a Shimadzu Pump Added to an Analyst Hardware Profile?

The solenoid valves for Shimadzu pumps can be set up by editing the hardware profile and changing the pump configuration.

How Are Calibration and Integration Parameters Defined in MultiQuant™ Software?

The default integration parameters are defined in the User Integration Defaults or User Units & Calibration Defaults under the Edit menu in MultiQuant™ software. These settings should be established before creating a quantitation method.

MultiQuant™ MD Software Will Not Launch from Desktop

MultiQuant™ MD software will not launch if the Analyst® software security setting is set to Integrated or Mixed mode. To keep these security settings, launch MultiQuant from the Companion Software mode in the left-side vertical menu in Analyst. Otherwise, change the security settings to single-user mode to open MultiQuant MD from the desktop.

After Activating My Software License Key, the License File Was Not Emailed to Me

After the software license key was activated online at the SCIEX website, the license file was not emailed to the registered email address. This occurs when the email address is not entered correctly.

Trouble Importing Sample List into Lipidomics Workflow Manager Project

In order to import a sample list successfully into Lipidomics Workflow Manager 1.0.5, the following software must be also installed: Microsoft Office 2010 and Access 2007 Runtime.

Considerations when Installing or Upgrading to Sciex OS 1.2

When upgrading to Sciex OS 1.2 from version 1.0, the software for Sciex OS 1.0 must be uninstalled prior to installing Sciex OS 1.2. LibraryView Framework version 1.1 must be removed as well. Certain companion software must be removed as well, and installed again after Sciex OS 1.2 is installed.

Low Virtual Memory Warning

If you receive warnings that your virtual memory is low youll need to increase the minimum size of your paging file

How to find Computer ID for Windows XP

Description of how to use the Command Prompt of Windows XP to find the Computer ID used when licensing Sciex software.

How to print from XIC Manager in PeakView

Description of the methods which can be employed to print from XIC Manager.

Does the Mascot.dll script work with Analyst 1.6 on a win 7 PC

Defines the issues and workarounds required to use the script.

ConfigUpdater.exe will not update instrument firmware.

Issues with Windows Firewall preventing ConfigUpdater from updating instrument firmware via Ethernet connection.

How to check Operating System Locale on Windows 7

SCIEX software is (unless stated otherwise in release notes) only supported on systems with a Locale of en-US United States. The process to accurately check your system locale is described below.