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Fast and practical high resolution separation and quantitation of charged and polar analytes.
The P/ACE Series is an automated, programmable capillary electrophoresis system designed to perform fast separations from complex samples. Separations occur in a capillary which is housed in an interchangeable cartridge with circulating liquid coolant for efficient temperature control. This finely regulated temperature control allows the use of high ionic strength buffers and large-bore capillaries necessary for analyzing difficult samples. With CE, methods are faster to develop, easier to validate, and less expensive to run. Note that different detectors are available to optimize performance for your application.
For every researcher there is an ideal analytical technology—one that helps you achieve your goals. Let us demonstrate how we can help you, request sample analysis now.
B52521 P/ACE™ MDQ Plus, Sample Temperature Control with UV/Vis Detection, Optional DAD & Optional LIF
The system includes a selectable-wavelength high sensitivity modular UV/Vis detector (includes 200, 214, 230 and 254 nm filters to optimize analyte specificity), UV source optics, temperature-controlled sample storage module and 32 Karat™ Software configured on a desktop controller. Installation Qualification, Operation Qualification 1 (OQ1) and documentation to aid in software validation is also included.
A robust sample injection design for demanding analytical requirements
Automated Sample Handling - The P/ACE MDQ Plus system offers fully automated methods and extended sample-handling capability for walkaway operation.
Quick-Change Electrodes - System electrodes and vial cap openers simplify user interaction, are designed to assure high strength and rigidity and are easily removed for maintenance.
Universal Vial and Cap Design - Prevents the capillary and electrode from physically interacting with the caps, creates a better seal, ultimately allowing for a robust, clean sample interface.
Sample Interface - Provides a robust pressure seal ensuring accurate and reproducible data.
Built-in auto-sampler, pressure & vacuum, and sample & temperature control
Capillary Temperature Control - Efficient CE separations rely on precise capillary temperature regulation to manage Joule heating within capillary. Proper temperature control plays important role in repeatability of analysis.
Sample Temperature Control - Settable temperature between 4 - 60°C helps maintain sample stability or perform functional assays.
Multiple Modes of Sample Introduction and Separation - The P/ACE MDQ Plus provides electrokinetic, pressure and vacuum introduction of samples. Introduction from either end of the capillary allows both ultrafast and high-resolution analyses.
Variable Pressure and Vacuum - The internal fluidic system operates with all common rinsing protocols, regulating these with a pressure-handling capability of -5 to 100 p.s.i.
Our capillary electrophoresis (CE) technology is used in numerous applications including academic research, industry, small molecule drug development and quality control.
Forensics / Drug Screening - While the highly polar nature of basic pharmaceuticals makes Liquid Chromatography complex, CE has the ability to excel at such separations. The robust nature of this tool and the ruggedness of this particular approach are appropriate for screening protocols used in forensic toxicology.
Image: Highly resolved separation of 20 basic drugs using low pH, where the capillary surface is essentially neutral and the amine functional groups on the solutes are maximally ionized.
Food and Beverage Manufacturing - The MDQ Plus, provides in-depth analysis of food compounds including anions, cations, organic acid content, and protein integrity, to better manage product process consistency, taste, quality, storage conditions, safety, adulteration and authentication.
Image: Analysis of white wine, revealing quantifiable compounds that effect the taste and feel.
Petrochemicals - Analysis of anion and cation content gives you a better understanding of the chemical makeup of petroleum and related products. For example highly purified terephthalic acid (PTA) and its esters are major components in the production of plastics and fibers like polyethylene glycol and polyester. The purity of PTA has a direct effect on the quality and color of the end products.
Image: With the P/ACE MDQ Plus, sensitive, reproducible, high resolution separations are achieved quickly, characterizing PTA and its major impurities.
Biofuels - The P/ACE MDQ plus already excels in ion analysis and is a natural fit for biofuel production. The fermentation of lignocellulosic biomass to ethanol is an attractive route to fuels that supplements the fossil fuels.ncorporating, ion analysis, protein purity assays, isoelectric focusing and sugar analysis by capillary electrophoresis is invaluable in monitoring the fermentation and purification processes used in ethanol production.
Image: CE Analysis of lignocellulosic biomass derived organic acids.
Water Quality and Environmental - With ever-increasing water demands, quick and efficient identification of impurities, analytes or other contaminating molecules within a water sample is a key step in managing the safety of our water supply. Water is also a vital component in industrial production of semiconductors, metal plating, and is used in large volumes in nuclear power plants and pulp and per mills. The P/ACE MDQ Plus identifies analytes that lead to corrosion as well as contaminants that contribute to downstream environmental pollution.
Image: Separation performance of the P/ACE MDQ Plus in under 5 min demonstrating use in identifying Inorganic Anions in water.
Height: 29.2 in (74.2 cm)
Door Open: 38.8 in (98.6 cm)
Width: 25 in (63.5 cm)
Depth: 28.4 in (72.1 cm)
188 lbs (85.3 kg) (includes UV/Vis Detector)
Voltage: 100 - 240 V; 50/60 Hz
Voltage Range: 1 to 30 kV programmable at 0.1 kV increments
3 to 300 μA programmable at 0.1 μA increments
Pressure Delivery Range:
-5 to +100 psi
Sample Temperature Control:
4 - 60°C
Capillary Temperature Control:
15 - 60°C
2 x 96-well plates
2 x 48 universal vials
2 x 48 0.3 ml vials or microfuge tubes
2 x 36 universal vials
200, 214, 254, 280 nm standard filter
190 - 600 nm (custom filter option
Diode Array (optional)
190 - 600 nm programmable
0.5 - 32 Hz scan collection frequency programmable
Laser Induced Fluorescence (LIF) (optional)
300 - 700 nm excitation range
350 - 750 nm emission range
0 - 1000 RFU
Source Lasers with 3 mW Power Output:
488 nm solid-state laser (included in A66528)
635 nm diode laser (optional)
Anion Analysis Kit: A53537
Cation Analysis Kit: A53540
Methods Development Kit: 501310
LIFLUOR dsDNA 1000 Enhance: 477409
dsDNA 1000 Kit: 477410
ssDNA 100R Kit: 477480
Capillary Test Kit: 338437
Supplies and Accessories
Universal Vials: A62251
200 μL Microvials (pkg of 100): 144709
Universal Vial Caps: A62250
Electrode Replacement Kit: A47775
Vial Cap Opener: A95348
Buffer Vial Tray (36 vials): A58254
Buffer Vial Tray (48 vials): A58255
Cartridge Assembly, 30 cm Capillary: A11147
Blank Cartridge Assembly Kit: 144738
Cartridge Rebuilding Kit: 144645
Cartridge Tubing Kit: 144689
Capillary Coolant (450 mL): 359976
|CE Installation Qualification Guide||05/01/2017|
|Estimation of (R)-Isomer and Other Impurities of Zolmitriptan API by CZE||01/01/2017|
|Separations Part Number Catalog||08/01/2016|
|CE-SELEX: Rapid Aptamer Selection Using Capillary Electrophoresis||07/22/2016|
|Installing the LIF Aperture and Probe Guide/Stabilizer||04/01/2016|
|P/ACE MDQ Plus Brochure||02/01/2016|
|ssDNA 100-R Kit Care and Use Instructions||06/01/2015|
|P/ACE MDQ Plus Methods Development Guide||05/12/2015|
|P/ACE MDQ Plus System Maintenance Guide||05/12/2015|
|P/ACE MDQ Plus System Overview Guide||05/12/2015|
|P/ACE MDQ Plus System Administration Guide||05/12/2015|
|P/ACE MDQ Cation Analysis Kit - Instruction Guide||05/12/2015|
|P/ACE MDQ Plus Site Planning Guide||05/12/2015|
|User Guide: P/ACETM MDQ User's Guide 32 KaratTM 8.0||04/01/2015|
|P/ACE MDQ Pre-Installation Guide 32 Karat Software||04/01/2015|
|P/ACE MDQ Plus Safety Guide||12/01/2014|
|CE-SELEX: Capillary Electrophoresis Selection of Aptamers||08/21/2014|
|dsDNA 1000 Method for 32 Karat||07/01/2014|
|ssDNA 100R Gel-Filling Separation Method for 32 Karat||07/01/2014|
|ssDNA-100R Separation Method for 32 Karat||07/01/2014|
|Cartridge Removal, Rebuild and Reinstallation||05/09/2014|
|Changing a Detector||05/09/2014|
|Chiral Analysis for Capillary Electrophoresis||05/01/2014|
|Capillary Electrophoresis Anion and Cation Analysis Kits||01/01/2014|
|Methods Development Strategy for Enantimoer Analysis using the PACE MDQ Chiral System||01/01/2014|
|Advancements in Forensic Toxicology: CZE Replaces GC/NPD as the Screen of Choice for Basic Drugs||01/01/2014|
|Anion and Cation Analysis||05/01/2012|
|P/ACE MDQ Installation and Maintenance Manual 32 KaratTM 8.0||03/01/2012|
|Capillary Electrophoresis with Laser-Induced Fluorescence Detection for Quality Analysis of Plasmid DNA||05/10/2010|
|Chiral Methods Development Kit User's Guide||03/01/2010|
|P/ACE MDQ Basic Training Workbook 32 Karat 8.0||11/01/2009|
|PACE MDQ Installation and Maintenance Guide||08/03/2001|
|A Fast and Accurate Method for the Analysis of Organic Acids and Anions in Fermentation Broth|
|Rapid Enantiomeric Separation of 101 Basic Drugs and Metabolites: A Generic Strategy Using Highly Sulfated Cyclodextrins|
|Rapid Enantiomeric Separation of Basic Drugs and Metabolites: A Universal Strategy for Ultra-Fast Method Development|
|Measuring the Capillary|
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