Every day you’re challenged to deliver faster, reliable results to inform clinicians. Now the power of LC-MS/MS technology is available with the Topaz system from SCIEX, developed with the demanding clinical lab in mind. It is the first FDA-reviewed integrated LC-MS/MS IVD system, that is open by design and closed when you need it.
Our robust technology and intuitive software bring advanced LC-MS/MS into the hands of the clinical analyst for the very first time. With cutting-edge ClearCore™ MD Software, SCIEX has simplified method development and streamlined workflows to give you valuable enhancements that you won’t get with traditional LC-MS/MS systems. In conjunction with the first FDA-cleared Vitamin D Assay, the Topaz system empowers your lab to do more, save more and deliver more confident results to support clinicians.
The Analytical Scientist Innovation Award Winner
"This could be another important step in allowing MS to be used in the clinic."
The software is very intuitive. I think the software and the standardized reagents are the two really big breakthroughs for this instrument. Dr. James Ritchie, Emory University Professor, Pathology & Laboratory Medicine
The Topaz system offers the best of both worlds so you can realize all the benefits of LC-MS/MS technology, faster and easier than you imagined possible. An open configuration driven by innovative ClearCore MD Software greatly simplifies method development. A closed locked Vitamin D Assay will get your clinical lab up and running without delay.
For The New Clinical Mass Spec User
Everything at your fingertips
A clean, grid-style user interface minimizes clicks and simplifies navigation menus, so you can focus on the task at hand.
Direct 1-click access to all system modules
Simplified menus with consolidated options
Minimal clicks possible to complete task
All systems go
ClearCore MD Software places everything right in front of you with convenient status panels that minimize distractions from important tasks.
Instant view of sample and instrument status from anywhere in the software
Live acquisition panel for immediate viewing of live sample data
Visual indicator lights to notify users of system status
…and the software has come a long way, it’s much easier for a med-tech or clinical laboratory scientist to program the instrument and know exactly where they’re at in the programing. Dr. James Ritchie, Emory University Professor, Pathology & Laboratory Medicine
Power for the Experienced Clinical Mass Spec User
Method development simplified
ClearCore MD Software provides automated features, streamlined workflows and real-time monitoring to enhance method development.
LC and MS/MS method development modules
Automated MRM optimization
Streamlined LC development with live LC injection within the MS module
Control of key features is just a few clicks away…
Access to direct LC control from the status panel
Instrument optimization module with simple, stepwise workflow
Batch editor module with onboard customization and direct import options
Manage your lab
Integrity of data analysis, reporting and test methods are maintained with embedded features that control system access and ensure LIS connectivity.
Multi-level user access with predefined user access settings
LIS connectivity with simplified bidirectional interface for data import/export
Option to lock developed methods to restrict editing or for pre-validated assays
Recapture Revenue by Bringing Your Send Outs In-house
By adopting the Topaz system, medium to large-size hospitals can recapture revenue by bringing tests back in-house and improve turnaround time, improve your quality and improve reliability and service.
With the Topaz system LC-MS/MS tests that are sent out for a significant fee can be brought back in-house at a lower cost. Starting with Vitamin D, incremental savings are realized annually, expanding as additional assays are adopted on the platform. With increasing testing volume, the payback period is shortened and lab profits realized.
Master Challenging Assays with Gold Standard Technology
For many assays, LC-MS/MS is considered the gold standard, delivering the specificity and sensitivity that other technologies lack. This enables clinical labs to deliver more confident results to support clinicians. This is the case with our new Vitamin D 200M Assay Kit, which delivers greater accuracy than standard immunoassay methods. The CDC has established a Vitamin D Standardization-Certification Program (VDSCP) and the SCIEX Topaz Vitamin D 200M Assay Kit has successfully met the rigorous performance criteria. While individually quantitating D2 and D3 forms, running the Vitamin D 200M Assay Kit on the Topaz system automatically differentiates between D3 epimers, providing the specificity to deliver highly accurate diagnostic results in a single analysis.
Topaz System for Sensitivity, Reproducibility and Robustness for in vitro Diagnostic Testing
With technological innovation and dependability you expect from SCIEX, the Topaz system is a high performance, easy to use, reliable LC-MS/MS system designed for in vitro diagnostic testing laboratories. The LC system provides both 1D and 2D LC capability allowing the option of online sample clean up enabling laboratorians to develop tests for even the most demanding clinical applications. Integrated with a new innovative state of the art software will have you up and running faster than ever before.
Best in class reliability, while maintaining the highest standards of accuracy
Quantitative and qualitative sensitivity to detect low concentration analytes
Dynamic range to see low to high concentration levels
Scan speed to clearly resolve similar analytes
Robust performance, minimal maintenance needs and dedicated customers support ensure high instrument uptime.
Reproducibility of results for four example analytes in 1500 injections in human plasma shows the stability of the MS system for consistent measurement day after day.