For research use only. Not for use in diagnostic procedures.
Simplifying the processing of biotherapeutic data for characterization and comparability can dramatically improve productivity. BioPharmaView software accelerates characterization and comparability studies and simplifies reporting, so you can make better decisions, faster.
Gain a comprehensive view by analyzing intact protein or protease digested forms in reduced or non-reduced states from both LC-MS and CESI-MS workflows performed on the TripleTOF® or X500B QTOF accurate mass systems. Now with the ability to process data-independent SWATH® Acquisition analyses. BioPharmaView Software enables you to quickly identify differences from site-to-site and from lot-to-lot, even with large datasets. The software's automated calculation of key attributes like DAR, PTM ratio and disulfide bond location helps you rapidly turn your data into answers.
Built for Speed and Accuracy — Biologics and Biosimilar Analysis
Accelerate your biologics and biosimilar characterization and comparability analyses with BioPharmaView™ Software. The software is powered by revolutionary data processing for core characterization workflows, such as intact mass, subunit and peptide mapping, and delivers exceptional assessment capabilities and data visualization in a high-throughput batch format.
Now with processing capabilities to enable a complete Multiple Attribute Methodology (MAM) workflow in a single software system. Define, track, and quantify product quality attributes (PQAs) as well as monitor known product impurities, and find new impurities with a streamlined solution.
Boost your biotherapeutic characterization analyses with automated data processing tools that allow you to:
Assess intact mass, subunit, and peptide mapping data quickly
Easily identify product differences from site-to-site and lot-to-lot
Perform a streamlined workflow for MAM to assess PQAs
Directly monitor known product impurities or host cell protein contaminants
Detect and flag new, unspecified impurities found in a sample
The software is designed from the ground up with both experts and non-experts in mind, so you can focus on delivering results quickly. The BioPharmaView Software is complete with tools to accelerate your time to results:
Process in-depth biologic characterization data at the intact, subunit, or peptide level
Perform a streamlined workflow for MAM to monitor PQAs and detect potential product impurities
Spend more time understanding your data and less time processing samples. With BioPharmaView Software you can:
Crunch numbers easily with batch processing functions and automated ratio calculations for both post-translational modifications as well as drug-to-antibody (DAR) analysis
Customize calculations and comparison tables for a holistic view of your attribute data
Develop and implement a Multiple Attribute Methodology (MAM) workflow with the new capabilities of BioPharmaView Software. This streamlined methodology can be used to replace, or complement, several conventional process development methods in a single simplified analysis.
BioPharmaView Software makes moving to a powerful high-resolution, accurate mass LC-MS based MAM assay easier with the all-in-one software to:
Define, track, and quantify product quality attributes (PQAs)
Monitor known potential impurities or host cell protein contaminants
Perform unspecified impurity testing with new peak detection algorithms
Intact analysis of antibody-drug conjugates (ADCs) can be challenging because of the size and complexity of the molecules. With BioPharmaView Software there’s no need to worry about your ADCs as the software:
Automates drug-antibody ratio (DAR) calculation and visualization
Presents a simplified—yet highly accurate view of protein deconvolution
You can now compare ADCs easily as you can see drug load and DAR across multiple samples. You can always be clear on just what you’ve got—and how much.
Proprietary SWATH® Acquisition for peptide mapping provides comprehensive data collection and eliminates the need for IDA criteria set-up and traditional method development.
Acquire high-resolution MS/MS for all precursor ions including all low abundance peptides and post-translational modifications (PTMs) with SWATH Acquisition. You can be confident that you’re truly collecting comprehensive and unbiased data and haven’t missed information dependent on peptide map workflows.
A standard, generic SWATH method can also be used in almost every biotherapeutic peptide mapping analysis further simplifying your workflow setup and reducing your time to results.
Using SWATH Acquisition, BioPharmaView Software processing, you can detect low-level modifications and confirm them in high-resolution MS/MS spectra within a single run. The image above illustrates how SWATH and BioPharmaView Software works together on the X500B QTOF system.