Keystone software: your SCIEX data in a single, vendor-neutral format that is secure, open and sharable

You depend on the data generated from mass spectrometers and other analytical instrumentation to meet the needs of your lab. The amount of data can be enormous and depending on the manufacturer of the instrument, the file formats are often unique and proprietary to each one. This complexity creates data management challenges to the enterprise including:

  • Data display - How can analytical results be displayed to the data consumers in the organization when different vendor-specific applications are required for each file-type?
  • Legacy software management - Will your organization require a stable of aging software from each instrument vendor to maintain the ability to review stored data in the future?
  • Future data access risk - Do you run the risk of being ‘locked out’ of your data in the future, because your data is in a proprietary binary file and not human-readable?

Organizations are now adopting an open, vendor-neutral file format called AnIML to address these challenges. The AnIML file format is an analytical data standard developed by ASTM International that can be used to store data from different analytical instruments in an open XML-based format. SCIEX has adopted this open standard to help you increase the utility of your SCIEX mass spectrometry data.

AnIML can provide a number of benefits to your organization:

  • A common data format for many analytic techniques (MS, NMR, UV, etc.) – one format for multiple data types
  • Requires a single viewing application to display data from many different instrument vendors – reduce or eliminate the dependency on vendor-specific software
  • Human-readable, open XML-based format – ensure access to results, even years into the future
  • Digital signatures for data integrity and security

SCIEX Keystone software allows companies to include SCIEX Analyst software data in their AnIML informatics workflows. 

Keystone Converter software allows you to convert the following SCIEX data into the AnIML format: 

  • Analyst software nominal mass data files (wiff): includes sample information, method information, technique information, spectra and chromatograms.  
  • Results table (.rdb): includes the results table, all chromatograms and the audit trail for that results table.  
  • Analyst software audit trail (.ata, .atd): includes all the audit records contained in the original files.

Keystone Viewer software offers an easy-to-use application for the display of AnIML files generated by Keystone or other sources of AnIML data. 

With Keystone software, your archived SCIEX data is secure, easily shareable, retrievable and available for future data review without the need for proprietary software.

Data archiving

Many labs provide access to legacy data via PDF documents. This approach can be limiting as the PDF no longer provides the real data, only a picture of the data. AnIML files generated by the Keystone Converter Software provide access to real data, stored in XML.

Software consolidation

Analytical data generated via different analytical techniques and various instrument vendors require an ever-growing list of applications and operating system software to ensure legacy data can be opened and interrogated. The open XML-based AnIML format allows easy access to all of this data via the Keystone Viewer Software or some other XML-based viewer.

LIMS integration

Many organizations use a LIMS system to provide access to analytical results. It can be challenging to integrate expensive proprietary-data viewing tools into an interface to display data across the organization. AnIML files from different vendors would require a single file viewer interface within the LIMS to accomplish this task.

Conversion workflow

  1. Once you have generated your nominal mass data, launch Keystone Converter Software*
  2. Select 1 or more files for conversion from a local drive or network location. Accepted formats** are .wiff, .rdb or audit trail files. 
  3. Initiate the conversion.
  4. Conversion of the files is begins and progress is displayed.
  5. The process is complete and files are stored in a directory of your choosing

Keystone Converter can also convert wiff files via the command line!


*Also requires Analyst 1.7.2 software to run in the background
**Keystone Converter does not work with Analyst TF or 7500 wiff data.

Viewer workflow

  1. Once your SCIEX nominal mass wiff files have been converted to AnIML format, they can be viewed using Keystone Viewer software.
  2. Launch Keystone Viewer and navigate to locate AnIML file(s) to open in the Viewer.
  3. Data within your AnIML file can be viewed in a variety of different ways:

The Experimental Workflow pane graphically connects samples with associated MS data

Multiple files can be selected for a tiled view

Multiple files can be selected and displayed in the overlay view

Results table information can also be displayed