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Posted June 25, 2018 in Blogs by Tom Knapman (0) Comments
"Bottoms Up" Proteomics Ahhhh beer. It's a ubiquitous drink found in over 90% of all countries around the world. Since the dawn of civilization, man has celebrated with beer where it can make even ... involved in the paper was my group whose focus is using proteomics to study post-translational modifications of proteins, Claudia Vickers whose interests lie in synthetic biology, and Glen Fox who does ... . We are working a lot with beer producers. For example, we have a collaboration with one craft brewer looking to use proteomics approaches to drive development of their production techniques
Posted May 2, 2016 in Blogs by Community Manager (0) Comments
Bottom-Up Proteomics: A Discussion with Christie Hunter Biocompare recently featured an article on Bottom-Up Proteomics . I had a chance to follow up with Christie Hunter and expand on some of the questions featured in the article: Read the Full Article > 1. What sample preparation tools for bottom-up proteomics researchers does SCIEX offer? A main focus of ours has been on industrializing bottom-up proteomics, from a sample preparation through to obtaining meaningful biological answers. We want to provide full, robust solutions to researchers so they can focus on doing
Posted November 7, 2016 in Blogs by Babu Purkayastha (0) Comments
The History of Isotopic Labels for Quantitative Proteomics Proteomics has become a vital tool for biological scientists performing research on the healthy and diseased states of living things ... is dynamic and quantities of proteins can change from one state to the next. Therefore, in order to be of the highest utility, proteomics experiments need to both identify and quantify proteins so that comparative studies can be done, such as between healthy cells and tumor cells, or the comparison of different treatment regimens. Proteomics has evolved significantly over the last 20 years
Posted April 18, 2016 in Blogs by Ken Hamill (0) Comments
Taking on Precision Medicine with Industrialized Proteomics White House, EU, UK, and Australia Make Major Investments What if we could deliver the right treatment at the right time, to the right person to better, more effectively treat complex disease? This is the promise of precision medicine, to be able to approach complex disease treatment and prevention by taking into account individual ... will need powerful tools and application support to perform the Omics research that creates the scientific foundation of precision medicine. SCIEX industrialized proteomics solutions, using
Posted May 4, 2016 in Blogs by Christie Hunter (1) Comments
Industrialize Your Quantitative Proteomics with Microflow Analysis High Throughput, Robust, Sample Analysis with Microflow SWATH® Acquisition Part 1 of a 3-Part Blog Series Many groups around the world are now using SWATH Acquisition on TripleTOF Systems for both quantitative proteomics experiments and biomarker research. The SWATH acquisition technique on a TripleTOF® 6600 system provides state-of-the-art quantitative proteomics analysis with unrivaled proteome coverage . With this workflow, researchers can routinely quantify 1000s of proteins per run
Posted May 13, 2016 in Blogs by Christie Hunter (0) Comments
Industrialize Your Quantitative Proteomics with the OneOmics Project Cloud Computing for SWATH ® Acquisition using the OneOmics™ Project Part 2 of a 3-Part Blog Series For many labs, the days are long gone when it was acceptable to run only a few samples a week for your quantitative proteomics projects. The pressure for faster turn-around times, to support larger cohort studies ... quantitative proteomics workflow. As shown in the figure below, once the SWATH data files are automatically uploaded, peptide and protein data is extracted and scored, metadata assigned, and data quality can
Posted June 21, 2017 in Blogs by Community Manager (0) Comments
Pushing Limits—A Powerful Proteomics Collaboration between SCIEX and Francis Crick Institute Recent Interview from the Analytical Scientist : When the effort of three collaborate to drive one ... metabolism and gene expression along with proteomics lab experts Kathryn Lilley (Cambridge Centre for Proteomics), and SCIEX came together. An interview featured in the Analytical Scientist with Mark ... more about this ambitious proteomics project, and what a successful collaboration looks like > Read the full article > RUO-MKT-18-5986-A
Posted May 24, 2016 in Blogs by Christie Hunter (0) Comments
Industrialize Your Quantitative Proteomics Using a More Simplified Sample Prep Robust, Reproducible, Sample Preparation Part 3 of a 3-Part Blog Series In part 1 and part 2 of this blog series we discussed how you can increase your efficiency for high throughput quantitative proteomics by industrializing your sample analysis and data processing. Microflow SWATH® Acquisition ... pipelines for targeted proteomic analysis to do population-scale proteomics by watching her webinar 2 : Proteome Centric Precision Medicine - Embracing Pathological Diversity . The Biomek
Posted October 23, 2019 in Blogs by Community Manager (0) Comments
A rising star in food allergen research: proteomics of shellfish allergens It’s important to know what you’re eating, especially if you suffer from a food allergy. About 220 million people worldwide live with a food allergy. 1 These numbers, along with the complexity and severity of conditions, continue to rise. In America, there are about 32 million food allergy ... , complementary proteomics approach to detect allergenic proteins. This approach could be the first step toward the development of a routine food testing assay. Colgrave and Broadbent’s study focused
Posted April 15, 2019 in General Question(s) by Breanna Duffy (3) Comments
Standard flow IDA proteomics using TripleTOF 5600 We have a TripleTOF 5600 coupled to a standard flow LC and electrospray. I was wondering what the capability of this instrument is to run untargeted proteomics using an IDA method. Most of the literature uses nanoflow chromatography and nanospray, but we do not have that equipment. Yes you can absolutely use your high flow TripleTOF system for untargeted proteomics! Here is a link to the SWATH performance kit protocol that you can use as a starting point for your acquisition method. The parameters that you will want
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