Advance your drug discoveries with reliable metabolite data that save time and money. Our range of solutions supports routine monitoring and complex identification.
Advance your drug discoveries with reliable metabolite data that save time and money. Our range of solutions supports routine monitoring and complex identification.
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Ease the burden of managing metabolite identification
As a leader responsible for metabolite identification in your organization, what keeps you awake at night and how can SCIEX help?
Video
Improving end-to-end metabolite identification with LC-MS/MS
Learn about the SCIEX end-to-end solution for metabolite identification, from method development to analysis. We explore the potential for electron activated dissociation (EAD) fragmentation to allow better-informed decision making.
Technical note
Rapid soft spot analysis using a routine biotransformation solution
See an approach to rapidly identify top metabolites in a routine manner
Confidently complete your metabolite identification studies through your development process with dependable instruments run on intuitive, compliant-ready software.
Our LC-MS systems offer fit-for-purpose sensitive and robust performance.
Workflow
Imagine the advantage of unambiguous metabolite identification using liquid chromatography-mass spectrometry (LC-MS) reducing the need for additional safety testing during drug discovery. Quickly and easily generate the information you need using routine assays that are robust and efficient, enabling confident decision-making while also saving time and money.
Suited for:
Reproducibility, reliability and carryover performance to match your quantitative workflows. Dependability you can count on, from injection to injection and batch after batch.
A uniquely engineered and versatile QTOF build to handle the demands of any high throughput laboratory.
Unleash the analytical power of the next-generation software platform for data acquisition and processing.
Keep your instruments performing at their peak, with multiple options for response time, repair coverage and maintenance.
Suited for:
Reproducibility, reliability and carryover performance to match your quantitative workflows. Dependability you can count on, from injection to injection and batch after batch.
A high-resolution mass spectrometry solution that combines powerful MS/MS sensitivity, fragmentation technology and a step-change in data independent acquisition.
Unleash the analytical power of the next-generation software platform for data acquisition and processing.
Keep your instruments performing at their peak, with multiple options for response time, repair coverage and maintenance.
Featured resources
Technical note
Confident identification of phase 1 metabolites using electron-activated dissociation (EAD)
See how complementary MS/MS spectra provided by electron activated dissociation (EAD) fragmentation enabled the identification of phase 1 metabolites to support drug metabolism studies.
Technical note
Confident characterization and identification of glucuronide metabolites using diagnostic fragments from electron activated dissociation (EAD)
Read about a streamlined method for the characterization and identification of conjugated structures during drug metabolism studies.
Technical note
Characterization and identification of therapeutic peptide catabolites
Read about rapid characterization and identification of therapeutic peptide catabolites from rat liver s9 fractions using the ZenoTOF 7600 system
Workflow
Complete metabolite assignments from biotransformation of siRNA, antisense and other oligonucleotides using reliable and trustworthy high-resolution mass spectrometry solutions that ensure fragmentation optimization. Identify oligonucleotide-derived metabolites with confidence, despite large isobaric overlaps and high structural similarities. Use custom software modifications that meet your specific analytical needs.
Suited for:
Reproducibility, reliability and carryover performance to match your quantitative workflows. Dependability you can count on, from injection to injection and batch after batch.
A high-resolution mass spectrometry solution that combines powerful MS/MS sensitivity, fragmentation technology and a step-change in data independent acquisition.
Determine impurities and biotransformations for a wide variety of modalities.
Keep your instruments performing at their peak, with multiple options for response time, repair coverage and maintenance.
Reproducibility, reliability and carryover performance to match your quantitative workflows. Dependability you can count on, from injection to injection and batch after batch.
A purpose-built QTOF system, designed specifically to accelerate everyday biologics characterization.
Determine impurities and biotransformations for a wide variety of modalities.
Keep your instruments performing at their peak, with multiple options for response time, repair coverage and maintenance.
Technical note
Rapid soft spot analysis using a routine biotransformation solution
See an approach to rapidly identify top metabolites in a routine manner
Technical note
Confident identification of phase 1 metabolites using electron-activated dissociation (EAD)
See how complementary MS/MS spectra provided by electron activated dissociation (EAD) fragmentation enabled the identification of phase 1 metabolites to support drug metabolism studies.
Technical note
Confident characterization and identification of glucuronide metabolites using diagnostic fragments from electron activated dissociation (EAD)
Read about a streamlined method for the characterization and identification of conjugated structures during drug metabolism studies.
Technical note
Characterization and identification of therapeutic peptide catabolites
Read about rapid characterization and identification of therapeutic peptide catabolites from rat liver s9 fractions using the ZenoTOF 7600 system
Technical note
Metabolite ID and relative quantification of oligonucleotides in plasma
Learn about a method developed for the identification, relative quantitation and structural confirmation of oligonucleotide metabolites in plasma, with sequence coverage at levels down to 1%.
Technical note
Identification and relative quantification of oligonucleotide metabolites from extracted rat plasma
Read about the identification, relative quantitation and structural confirmation of nine oligonucleotide metabolites spiked in a rat plasma extract.
Brochure
Ease the burden of managing metabolite identification
As a leader responsible for metabolite identification in your organization, what keeps you awake at night and how can SCIEX help?
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