Your trusted partner in biomarker quantitation. With SCIEX, you get innovative solutions backed by a legacy of accuracy and precision.
Whether high or low abundance, from trace levels to trusted data, count on SCIEX for the accuracy your biomarker quantitation demands.
Navigate biomarker quantitation with confidence, exploring the potential of trusted LC-MS/MS solutions designed to simplify and accelerate your workflow. From lab-tested methods to innovative hardware and software, move drug candidates through the pipeline with efficiency and reliability, so you can confidently characterize and quantify, including low-abundant ions, faster than ever before.
Easy-to-use, integrated software streamlines the process, while dependable expert support ensures you can refine workflows and advance promising candidates without hesitation.
Workflow
Our systems provide in-depth coverage that enables you to characterize and confidently quantify biomarkers, even low abundant ions. With different technology options for specific needs, SCIEX can help you get the answers you need.
Reproducibility, reliability and carryover performance to match your quantitative workflows. Dependability you can count on, from injection to injection and batch after batch.
Setting a new standard for instrument resilience and robustness, the SCIEX 7500+ system gives you the confidence to face evolving analytical challenges. Tackle tight timelines with exceptional sensitivity and with the power to control your instrument downtime.
Unleash the analytical power of the next-generation software platform for data acquisition and processing.
Keep your instruments performing at their peak, with multiple options for response time, repair coverage and maintenance.
Featured resources
Technical note
High sensitivity quantitation of acylcarnitines using the SCIEX 7500 system
Learn how to achieve high sensitivity and reproducibility with a simple sample preparation method and a fast LC gradient with 8 carnitine and acylcarnitine biomarkers monitored in rat plasma.
Technical note
Sensitive bioanalysis of galactosyl sphingosine (GalSPH) and glucosyl sphingosine (GluSPH) in cerebral spinal fluid
Sensitivity for 2 glycosphingolipids (GluSPH and GalSPH) was evaluated in cerebral spinal fluid using the SCIEX 7500 system. An assay was developed using HILIC chromatography along with positive MRM analysis and electrospray ionization. Calibration curves were generated on the SCIEX 7500 system and the QTRAP 6500+ system to assess the sensitivity difference.
Technical note
Identification and quantitation of lipid biomarkers using accurate mass spectrometry
We demonstrate a combination of qualitative and quantitative workflows to identify and quantify lipid biomarkers in a mouse brain matrix.
Suited for:
Reproducibility, reliability and carryover performance to match your quantitative workflows. Dependability you can count on, from injection to injection and batch after batch.
A high-resolution mass spectrometry solution that combines powerful MS/MS sensitivity, fragmentation technology and a step-change in data independent acquisition.
Unleash the analytical power of the next-generation software platform for data acquisition and processing.
Keep your instruments performing at their peak, with multiple options for response time, repair coverage and maintenance.
Workflow
Discover better analytical solutions that meet your needs for in-depth coverage with robust and sensitive performance. Confidently characterize and quantify large-molecule biomarkers—including low-abundant ions—faster than ever before with easy-to-use, integrated software. All of our solutions are complemented by dependable access to an expert support team eager to help you improve your workflows and move promising candidates forward.
Suited for:
Reproducibility, reliability and carryover performance to match your quantitative workflows. Dependability you can count on, from injection to injection and batch after batch.
A high-resolution mass spectrometry solution that combines powerful MS/MS sensitivity, fragmentation technology and a step-change in data independent acquisition.
Unleash the analytical power of the next-generation software platform for data acquisition and processing.
Keep your instruments performing at their peak, with multiple options for response time, repair coverage and maintenance.
Reproducibility, reliability and carryover performance to match your quantitative workflows. Dependability you can count on, from injection to injection and batch after batch.
Setting a new standard for instrument resilience and robustness, the SCIEX 7500+ system gives you the confidence to face evolving analytical challenges. Tackle tight timelines with exceptional sensitivity and with the power to control your instrument downtime.
Unleash the analytical power of the next-generation software platform for data acquisition and processing.
Keep your instruments performing at their peak, with multiple options for response time, repair coverage and maintenance.
Technical note
High sensitivity quantitation of acylcarnitines using the SCIEX 7500 system
Learn how to enable high sensitivity and reproducibility with a simple sample preparation method and a fast LC gradient with 8 carnitine and acylcarnitine biomarkers monitored in rat plasma.
Technical note
Sensitive bioanalysis of galactosyl sphingosine (GalSPH) and glucosyl sphingosine (GluSPH) in cerebral spinal fluid
Sensitivity for 2 glycosphingolipids (GluSPH and GalSPH) was evaluated in cerebral spinal fluid using the SCIEX 7500 system. An assay was developed using HILIC chromatography along with positive MRM analysis and electros
Technical note
Identification and quantitation of lipid biomarkers using accurate mass spectrometry
We demonstrate a combination of qualitative and quantitative workflows to identify and quantify lipid biomarkers in a mouse brain matrix.
Technical note
Sensitive multiplexed quantitation of protein biomarkers for early drug discovery and development
Dive into a new solution for highly sensitive quantitation of surfactant proteins in human plasma at a signature peptide level with low-ng/mL lower limits of quantitation.
Technical note
Sensitive quantitation of an antibody-drug conjugate (ADC) using LC-MRMHR in human serum
This technical note demonstrates a sensitive method for quantitation of trastuzumab deruxtecan (TDx) in human serum using high-resolution accurate mass spectrometry. A lower limit of quantitation (LLOQ) of 0.05 µg/mL (1 ng on column) was achieved in extracted human serum samples.
Confidently discover, quantify and translate previously inaccessible and challenging biomarkers with solutions designed to facilitate in-depth, comprehensive analysis.
Advance the development of your next therapeutic drug with easy-to-operate, integrated analytical systems that can provide new insights into ADME-Tox and DMPK. Rapidly and comprehensively characterize drug candidates with robust and sensitive solutions for identification, monitoring and quantitation.