Unlock the future with multiple biotherapeutic assays on one platform

PA 800 Plus system

The quality assessment of your biopharmaceuticals deserves the best. Using capillary electrophoresis (CE) on the PA800 Plus system lets you challenge the status quo and break through analytical boundaries.

Ultra-high quality separation day in and day out with intuitive kit-based applications for capillary capillary electrophoresis sodium dodecyl sulfate (CE-SDS), capillary gel electrophoresis (CGE), capillary isoelectric focusing (cIEF) and capillary zone electrophoresis (CZE) will help you understand your biotherapeutics and vaccines better to advance them with confidence. 

The PA 800 Plus system can help you with:

  • Monoclonal antibodies (mAbs) and mAb variants
    • Charge heterogeneity (cIEF)
    • Purity of mAbs and mAb variants (CE-SDS)
    • N-linked gylcan analysis
  • In vitro transcribed RNA (IVT RNA)
    • Purity and integrity of mRNA and other IVT RNA (CGE)
    • Purity and size of critical starting material (CGE)
  • Viral vectors
    • Capsid protein purity and ratios (CE-SDS)
    • Virus genome integrity (CGE)
    • Empty-full capsid ratio (CGE and CE-SDS)
    • Purity of critical starting material (CGE)
    • Residual host cell DNA (CGE)
  • Gene editing
    • Purity of guide RNA (CGE)
    • Purity and integrity of Cas9 mRNA (CGE)

Status: Available    Require more information? Learn more

Key features

Data quality

Achieve highest resolution with unmatched reproducibility using QC-trusted technology, including precise capillary temperature control.



Gain valuable insights into quality attributes of your biopharmaceuticals with intuitive kit-based assays including CE-SDSCGE, cIEF, and CZE.



Rest assured when sensitivity needs change. Switch between UV and laser-induced-fluorescence (LIF) detection within minutes.


Portability matters

Confidently transfer methods from lab to lab or between CE systems from SCIEX.


Compatibility and QC

Meet data management needs with compatibility with the Empower Chromatography Data System (CDS) from Waters and the Thermo Scientific™ Chromeleon™ Chromatography Data System (CDS) as well as Windows10. Rely on technology trusted by US Pharmacopeia, such as the USP General Chapter 129.

Precision analytics for oligonucleotide, cell and gene therapy

As the technologies for manufacturing and analysis of gene therapy products continue to evolve, it’s important to keep up to date on growing industry trends and analytical advancements. This compendium can help advance your gene therapies and oligonucleotide therapeutics to the next level with the latest tools and methods.

Download your copy of the compendium

Related applications

Glycan analysis

Manage development timelines with scalable N-linked glycan analysis solutions that rapidly identify therapeutic antibody glycosylation profiles.

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Charge heterogeneity analysis

Take back your time with simple and transferrable methods to analyze mAb charge variants for identity and stability with high resolution.

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Cell line analysis

Gain the advantage of knowledge up front, with rapid, sensitive and accurate CE-based cell line analysis strategies.

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mRNA analysis

Achieve integrity, purity and encapsulation information of IVT RNAs and obtain insights into poly-A tail length and distribution with the highest data quality.

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Plasmid DNA

Gain confidence in critical starting material from development to QC with trusted CGE technology to support the production of mAbs, mRNAs, viral vectors and more. 

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Cell and gene therapy

Take charge of the purity and integrity of viral vectors while leveraging outstanding data quality. Overcome secondary structures and maximize your gene editing success. 

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