Charge variant analysis in as little as 5 minutes
Fast and simple charge heterogeneity
CZE Rapid charge variant analysis kit
Rapid charge variant analysis
Simplify analysis and maximize lab time, with fast, powerful separations based on sample mobility.
Resolve a native state molecule’s charge variants with more resolution than icIEF or ion exchange chromatography.
Quantify charge variants with a buffer that serves as both a separation matrix and dynamic coating with a bare fused silica capillary.
Compatible products
PA 800 Plus system
From development throughout QC, this established system delivers high-quality data with kit-based workflows.
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CZE rapid charge variant analysis kit
This pre-assembled bare-fused silica 8-capillary cartridge (8 × 30 cm, P/N 5080121; 8 × 50 cm, P/N 5080123) is compatible with the DNA 20 kb Plasmid and Linear kit and the BioPhase 8800 system.
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Pre-assembled capillary cartridge
Pre-built bare-fused silica capillary cartridge with a total capillary length of 30.2 cm and an inner diameter of 50 µm. Detection window is laser etched and capillary ends are precision cut ensuring the highest level of repeatability in your assay.
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Related applications
Cell line analysis
Set the pace with confidence. Cell line monitoring and analysis solutions verify the identity, purity and stability of lead candidates with high throughput strategies that are ready for automation
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Charge heterogeneity analysis
Pursue the end goal with confidence. Achieve the full picture and accelerate decisions with comprehensive characterization of biopharmaceutical charge variants.
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Resources
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Technical note
Native state charge variant analysis of commercialized monoclonal antibodies in minutes
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Technical note
Rapid charge heterogeneity analysis of new therapeutic protein modalities
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Technical note
Subunit charge variant characterization in the native state
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Brochure
Consumables and reagents catalog
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Technical note
A Rapid, high-resolution lot release assay for co-formulated mAbs with CZE
Discover a novel workflow for high-speed lot release assay using capillary zone electrophoresis on the PA800 Plus system. This kit-based workflow provides quantitative results with simple sample preparation.