QTRAP® 4500 LC-MS/MS System

The LC-MS/MS workhorse, intelligently re-engineered

Known as the LC-MS/MS workhorse, this is the intelligently re-engineered design of the 4000 QTRAP Platform, and sets a new benchmark for robust quantitation and library searching.

The system is ideal for laboratories requiring ultimate robustness, ruggedness, and reliability for high-throughput screening of many compounds in many samples every day.

QTRAP 4500 LC-MS/MS System
Key features

Mass range

Triple quadrupole: 5 – 2,000 Da. linear ion trap: 50 - 2,000 Da

Flexible ionization options

Options include electrospray ionization (ESI) and heated nebulizer ionization probes.

Polarity switching

50 msec in MRM and Scheduled MRM™ modes

Detector type

AcQuRate™ Pulse Counting CEM

Features

Turbo V™ Ion Source, pulse counting detector

Scan types

Q1 MS, Q3 MS, product ion, precursor ion, neutral loss or gain, MRM, EMS, EPI, ER, MS3, MRM3, TripleTrap™ Scanning

Ionization sources

Turbo V; TurboIonSpray; Atmospheric-pressure chemical ionization (APCI); DuoSpray®, Phytronix LDTD, Advion LESA Clarity, Digital PicoView, NanoSource

Cutting Edge and Reliable Technology

The best of both

Maximize uptime with a system that can handle even the most difficult matrices with ease. Includes legendary Turbo V technology, patented QJet on Guide design, and the ultimate pulse counting detector.

Turbo V Source

This legendary source provides high-sensitivity analysis over a wide range of flow rates with quick-change APCI and TurboIonSpray® probes.

QJet® Ion Guide

The patented design yields excellent ion containment and operates at high pressure, providing better collisional focusing to enhance ion transmission for ultimate sensitivity.

AcQuRate Pulse Counting Detector

The detector technology works in combination with a pulse overlap correction algorithm, enabling more accurate and precise ion detection over a wide dynamic range.

Resources

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4500 Series of Instruments Site Planning Guide (ZH)

4500 Series of Instruments Site Planning Guide (ES)

4500 Series of Instruments Site Planning Guide (JA)

Quantification of Dopamine, Epinephrine, Norepinephrine in Human Plasma by SCIEX Liquid Chromatography-Tandem Mass Spectrometry

SCIEX LC-MS-MS Application Technology on Origin Identification of Dairy Products based on Alpha-lactalbumin and Beta-lactoglobulin

Determination of Six Antiepileptic Drugs in Serum by SCIEX Triple Quad System (ZH)

Quick Determination of 105 Doping in Animal derived Food by QTRAP System

Rapid Determination of 41 Primary Aromatic Amines in Water

Determination of Aflatoxins B and G in Grain

A Rapid Screening and Quantitative LC-MS-MS Method of 189 Veterinary Drug Residues in Animal Food by Triple QuadTM 3500

LC-MS-MS Method for Determination of 523 Pesticide Residues in Traditional Chinese Medicine

Determination of Nitro-PAH in River Water

The Solution of Analysis 13 Nitrosamines in Drinking Water by LC-MS-MS

Determination of Six Antipsychotic Drugs in Serum by SCIEX Liquid Chromatography-Tandem Mass Spectrometry

Establish a rapid and efficient method for the determination of nitrosamines in cosmetics and personal care products

Determination of Chloramphenicol Thiamphenicol and Florfenicol Residues in Fish

Determination of Tetracycline Antibiotic Residues in Animal-derived Food

QuEChERS LC-MS-MS Solutions for Detecting Carbamate Pesticides in Soils

Quantification of 74 Prohibited Hormones in Cosmetics Using LC-MS-MS System

Application of LC-MS/MS in Chinese Pharmacopoeia

Determination of Liposoluble Vitamins in Micro Blood Samples by SCIEX Liquid Chromatography Tandem Mass Spectrometry

Quantitative Analysis of Fentanyl and Analogues in Human Whole Blood

Identification of clonidine hydrochloride metabolites in pig feces using QTRAP mass spectrometry and LightSight software

Determination of Sulfonamide Residues in Chicken

Determination of Malachite Green and Crystal Violet Residues in Fish

The Application Solution for Determination of Minoxidil and Other 6 Kinds of Components in Cosmetics by LC-MS-MS Method

Determination of Linezolid and Fluconazole in Plasma by SCIEX Liquid Chromatography-Tandem Mass Spectrometry (ZH)

Determination of Beta-agonist Residues in Meat

Rapid Screening and Quantification of 223 Illegal Drug Residue in Feed Using LC-MS/MS (ZH)

Rapid Screening of Phenyl-sulfonate Ester Genotoxic Impurities by pMRM-IDA-EPI

Determination of 23 Phthalate Esters in Drinking Water By LC-MS-MS

Determination of Quinolone Residues in Animal-derived Food

Determination of Animal Species Origin from Blood Products by LC-MS-MS

Determination of Genotoxic Impurities Methyl Methanesulfonate and Ethyl Methanesulfonate on SCIEX Triple QuadTM 4500 system

Determination of 23 Phthalate Esters in Cosmetics By LC-MS-MS

SCIEX QTRAP Mass Spectrometry for Rapid Detection of 90 Illegal Additives such as Sildenafil and Sildenafil Analogs in Health Care Products

Determination of roxarsone in animal feeds using solid-phase extraction coupled with high performance liquid chromatography-tandem mass spectrometry

Determination of Bongkrekic Acid in Rice Noodles and Tremella on SCIEX Triple QuadTM 4500 System

Determination of Malachite Green and Crystal Violet Residues in Fish

The Application of Multiple Heart-Cutting 2D-LC- X500B in the Analysis of Drug Impurities in Proinsulin (ZH)

Determination of trace angiotensin II in plasma with SCIEX Triple Quad 4500 LC-MS/MS system (ZH)

Determination of 13 Bile Acids in Serum by SCIEX Liquid Chromatography-Tandem Mass Spectrometry

Determination of 8 Polar Pesticides and metabolites in Plasma and Urine Without Derivatization (ZH)

Characterization and Identification of flavonoids in Traditional Chinese Medicine Artemisia rupestris L by SCIEX QTRAP 4500

Simultaneous Determination of Aldosterone and Angiotensin I from Human Plasma Using LC-MS/MS (ZH)

Rapid Determination of Hexabromocyclododecane and Tetrabromobisphenol A in Water

The Application of Analysis 13 Haloamides in Drinking Water by LC-MS-MS

Determination of Genotoxic Impurities N-nitroso-N-methyl-4-aminobutyric acid on SCIEX Triple QuadTM 4500 system

Identification of Carbamate Pesticide Metabolites in Soil with LightSight Software Combined with QTRAP System

The solution for amantadine, rimantadine and ribavirin residues in animal-derived foods by LC-MS /MS

Determination of Aflatoxins B&G in Grain

Quantitative Analysis of Nine Haloacetic Acids in Water Environment by X500R QTOF System (ZH)

LC-MS-MS Method for Rapid Determination of 30 Forbidden Pesticides In Traditional Chinese Medicine

The Application Solution for Determination of Fluconazole and other 8 Kinds of Components in Cosmetics by LC-MS-MS Method

Determination of Tetracycline Antibiotic Residues in Animal-derived Food

Analysis of Six Organotin Compounds in Food package Material by LC-MS-MS

Determination of NMDA in Ranitidine Hydrochloride by LC-MS-MS

The application of 2D-LC-QTRAP in the analysis of drug impurities CN

A Rapid Screening and Quantification Method of Forbidden and Restricted Pesticides in Traditional Chinese Medicine by LC-MS-MS

Simultaneous Determination of 14 Paralytic Shellfish Toxins in Seafood using LC-MS-MS

Determination of Nitrofuran Metabolites in Animal-derived Food

Analysis 106 Compounds in Cell Supernatant by Using LC-MS-MS

Determination of Phenoxy Carboxylic Acids Herbicide in Water by LC-MS-MS

Determination of Caspofungin Posaconazole Voriconazole N-Oxide and Voriconazole in Plasma by SCIEX Liquid Chromatography-Tandem Mass Spectrometry

Identification and Quantitation of Fentanyl and Analogues in One Injection by SCIEX QTRAP

A Rapid Quantitative Method of LC-MS /MS for Dichlorvos in Sea Cucumbers (ZH)

The power of SCIEX Triple Quad liquid chromatography tandem mass spectrometry to detect polycystic ovarian syndrome related androgen (ZH)

Improving Sensitivity for Trace Pesticides Residues Quantification in Drinking Water using Trap-Elute MicroLC-MS with Large Volume Sample Loading

Determination of Monohydroxylated PAH in River Water

Determination of Chloramphenicol Thiamphenicol and Florfenicol Residues in Fish

Determination of seven Antineoplastic and antibacterial drugs in Serum by SCIEX LC-MS/MS

Simultaneous Determination of 7 Kinds of Local Anesthetics in Cosmetics by High Performance Liquid Chromatography-Mass Spectrometry (ZH)

SCIEX LC-MS-MS Application Technology on Quantitation of Lactoferrin in Dairy Products

Detection of 24 Perfluoroalkyl Substances in Surface water by Triple Quad TM 4500

Simultaneous quantitative analysis of metronidazole and chloramphenicol in chicken by SCIEX LC MS-MS

Simultaneous determination of five cytarabine metabolites and analogs with SelexION Ion mobility Mass Spectrum (ZH)

Detection of Methylmalonic Aciduria by Ion Chromatography Tandem Mass Spectrometry (ZH)

Determination of Quinolone Residues in Animal-derived Food

Instrument Front-End Cleaning Procedure For Customers

Identification of Degradation Products of Simvastatin

Microsoft Word - 3_Identification of the metabolites of tetrachloronamide by QTRAP® 4500 Complex Mass Spectrometry System_legal comments.docx

Searching QTRAP MSMS Data with Libraries in SCIEX OS-Q

Fast and Simultaneous Analysis of Ethanol Metabolites and Barbiturates in Human Urine

Highly sensitive LC-MS/MS method for the quantification of pesticides in tea matrix using the QTRAP 4500 LC-MS/MS System

Powerful Qual/Quant Scan Modes of QTRAP® System Technology

Fast Screening Method for 86 Forensic Analytes in Human Urine

Method Development for Fake Lamb Meat Detection using SCIEX QTRAP 4500 system (CH)

Comprehensive Quantitation and Identification of Pesticides in Food Samples Using the New Eksigent ekspert ultraLC 100 and the New AB SCIEX QTRAP 4500 System

Analysis of PFAS in drinking water with EPA Method 537.1 and the SCIEX QTRAP® 4500 System

SCIEX QTRAP 4500 LC-MS/MS System Compendium of food testing applications

Quantitation of Aflatoxin M1 in Milk using SCIEX QTRAP® 4500 LC-MS/MS System

Cannabis for Per Se Law Testing in Whole Blood using theSCIEX Triple Quad QTRAP 4500 LC-MS/MS System

MassSpectator - Food Safety Edition

Nitrosamine Disinfection Byproducts in Drinking Water, LC-MS

Identification and Quantification of Designer Drugs in Urine by LC-MS/MS

Microsoft Word - Loratadine tech note 29Sep2017.docx

AB SCIEX LC-MS/MS Analysis of Emerging Food Contaminants - Quantitation and Identification Acrylamide in Starch-Rich Food

Resolution of Ether- and Diacyl-Linked Phospholipids by DMS

Higher Confidence in Identification with QTRAP_AB SCIEX.docx

Extending Metabolome Coverage-untargeted Metabolomic Workflows

CYP4500 Protein Assay - Human Induction Kit Extended Panel

Simple and Robust LC-MS/MS Method of Phosphatidylethanol (PEth) in Whole Blood Using Luna® Omega Polar C18 Column

Quantification of Major Metabolites of K2 in Human Urine

Amlodapine Bioanalysis v10.docx

AB SCIEX Rapid Quantitation and Identification of Carbendazim in Orange Juice using LC-MS/MS

High Throughput Automated Sample Preparation and Analysis Workflow for Comprehensive Forensic Toxicology Screening using LC/MS/MS

Análisis Rápido de Nitrosaminas Genotóxicas por HPLC-MS/MS

Solución total QTRAP en Espectrometría de Masas en la detección de aditivos en 68 productos para la Salud comunmente usados en China

Quantitative Analysis of Fentanyl and Analogues in Whole Blood - QTRAP 4500 System

Microsoft Word - FINAL CF1836_RUO-MKT-02-2173-A_Automation Ethanol Metabolites in Urine.docx

Dont miss Synthetic Drug Present in Sample

Identification and Quantitation of Poisonous Alkaloids in Blood by SCIEX QTRAP

Determination of Nitrofuran Metabolites in Animal-derived Food

Aflatoxins in Milk

Mometasone

Nitrosamines Flyer (PT)

SCIEX vision Journal Issue 4

Its a Triple Quadrupole and so much more

Quantify NDMA using the SCIEX QTRAP 4500 LC-MS/MS System

Compruebe y maximice la calidad de sus productos agriculturales

Nitrosamines impurity analysis using SCIEX QTRAP® 4500 LC-MS/MS System

Determination of Beta-agonist Residues in Meat

List of Published Articles of Therapeutic Drug Monitorings (TDM) with SCIEX LC-MS/MS System (Volume 2)

List of Published Articles on Quantitative Methods of Clinical Diagnostics/Lab-Developed Tests (LDTs) with SCIEX LC-MS/MS System

Catalogue of Literatures on target lipidomics using Triple Quad QTRAP mass spectrometry (Volume 1)

Catalogue of Literatures on Metabolomics using SCIEX mass spectrometry (Volume 1)

List of Published Articles of Therapeutic Drug Monitorings (TDM) with SCIEX LC-MS/MS System (Volume 3)

List of Published Articles with SCIEX LC-MS-MS System-Clinical-Volume 4

Determination of Sulfonamide Residues in Chicken

Folder for The Flyers of Food Safety Monitoring Holistic Solution

List of Published Articles with SCIEX LC-MS-MS System-Clinical-Volume 3

List of Published Articles with SCIEX LC-MS-MS System-Clinical-Volume 2

List of Published Articles of Therapeutic Drug Monitorings (TDM) with SCIEX LC-MS/MS System (Volume 4)

Catalogue of Literatures on untarget lipidomics using SCIEX high resolution mass spectrometry (Volume 1)

Catalogue of Literatures on Traditional Chinese Medicine (Volume 1)

List of Published Articles of Therapeutic Drug Monitorings (TDM) with SCIEX LC-MS/MS System (Volume 1)

Quantitation on the SCIEX QTRAP 4500 LC-MS/MS System with the ExionLC AD System

Flexible NanoSpray® III Source, for nanoflow and CESI applications

MRM3 Quantitation - Highest Selectivity in Complex Matrices

High Selectivity Quantification of Protein Isoforms using MRM3 Workflow

Allerges_vMethod_TechNote_newTemplate_vApril27-2016-v4_sp

Rapid Determination of Nitrosamines of Genotoxic Impurities in Metformin by Triple QuadTM 4500 System

Analysis of Genotoxic Nitrosamines in Losartan and Ranitidine Active Pharmaceutical Ingredients

The LC-MS/MS Workhorse SCIEX 4500 Series Mass Spectrometers

Challenges of screening and identifying NPS in the forensic laboratory

Application of SCIEX 3500 triple quadrupole liquid chromatography mass spectrometry platform for the detection of 30 prohibited pesticides and their metabolites in Chinese herbal medicines and decoction pieces

Novel Psychoactive Substances - Infographic

Detecting and identifying NPS: a brief history

The growing problem of NPS

Overcoming NPS screening challenges in the forensic laboratory

Detecting novel psychoactive substances - the workflow

SCIEX中国药典新规定的完整解决方案

基于SCIEX三重四极杆质谱系统对食品接触材料中丙烯酰胺迁移量的测定

Rapid and Sensitive Analysis of a 93-Compound Forensic Panel in Urine

PowerPoint Presentation

Approaches to drug screening using Triple Quadrupole, QTRAP and QTOF technologies

Harnessing the power of mass spectrometry for early novel psychoactive substances (NPS) detection

QTRAP®质谱系统在化合物筛查中的工作流程

LC-MS/MS 技术平台

快速测定土壤和沉积物中38种初级芳香胺化合物

Food-Fraud-Authenticity

Fast and simultaneous analysis of ethanol metabolites and barbiturates using the QTRAP® 4500 LC-MS/MS system

Rapid and Sensitive Analysis of a 93-Compound Forensic Panel in Urine using the QTRAP/Triple Quad 4500 LC-MS/MS System

Forensic Compendium

Techniques and solutions for forensic drug screening: an interview with Timothy Fassette

The age of novel psychoactive substances

Method establishment of medium and long chain acyl-coenzyme A in biological samples

Determination of Five Antibiotics and their Metabolites in Serum by SCIEX LC-MS/MS

SCIEX Tandem Mass Spectrometry Method for Quantification of Chondroitin Sulfate and Dermatan Sulfate by Methanolysis Derivatization

The Determination of Zearalenone in Traditional Chinese Medicines using LC-MS/MS

LC-MS/MS法快速测定动物源食品中205种兽药的完整解决方案

Streamlining forensic laboratory informatics for NPS screening and quantification

应用LC-MS/MS快速分析化妆品中10种α-羟基酸

白酒类饮料中9种甜菊糖苷的液质快速检测方法

Software

Software        
Name File Size Release Date Release Notes Download
MasterView 1.1 Software 560MB

12.01.14

Release Notes

Download
PeakView 2.0 Software 569 MB

01.01.14

Release Notes Download
PeakView 2.1 Software 537 MB

01.01.14

Release Notes Download
MasterView 1.0 Software

1.5 GB

12.01.13

Release Notes Download
MRM3 Optimization for Analyst 1.5.1 Software 1.6 MB

12.01.13

Release Notes Download
Analyst 1.6.2 Software 445 MB

06.01.13

Release Notes Download
Analyst 1.6.1 Software 423 MB

03.01.12

Release Notes Download
Analyst 1.5.1 Software 316 MB

06.01.10

Release Notes Download

All software downloads