QTRAP® 4500 LC-MS/MS System

The LC-MS/MS workhorse, intelligently re-engineered

Known as the LC-MS/MS workhorse, this is the intelligently re-engineered design of the 4000 QTRAP Platform, and sets a new benchmark for robust quantitation and library searching.

The system is ideal for laboratories requiring ultimate robustness, ruggedness, and reliability for high-throughput screening of many compounds in many samples every day.

QTRAP 4500 LC-MS/MS System
Key features

Mass range

Triple quadrupole: 5 – 2,000 Da. linear ion trap: 50 - 2,000 Da

Flexible ionization options

Options include electrospray ionization (ESI) and heated nebulizer ionization probes.

Polarity switching

50 msec in MRM and Scheduled MRM™ modes

Detector type

AcQuRate™ Pulse Counting CEM

Features

Turbo V™ Ion Source, pulse counting detector

Scan types

Q1 MS, Q3 MS, product ion, precursor ion, neutral loss or gain, MRM, EMS, EPI, ER, MS3, MRM3, TripleTrap™ Scanning

Ionization sources

Turbo V; TurboIonSpray; Atmospheric-pressure chemical ionization (APCI); DuoSpray®, Phytronix LDTD, Advion LESA Clarity, Digital PicoView, NanoSource

Cutting Edge and Reliable Technology

The best of both

Maximize uptime with a system that can handle even the most difficult matrices with ease. Includes legendary Turbo V ion source, QJet ion guide design, and the ultimate pulse counting detector.

Turbo V Source

This legendary source provides high-sensitivity analysis over a wide range of flow rates with quick-change APCI and TurboIonSpray® probes.

QJet® Ion Guide

The innovative design yields excellent ion containment and operates at high pressure, providing better collisional focusing to enhance ion transmission for ultimate sensitivity.

AcQuRate Pulse Counting Detector

The detector technology works in combination with a pulse overlap correction algorithm, enabling more accurate and precise ion detection over a wide dynamic range.

Resources

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TIAFT_2016_XiangHe_Adrian Taylor PS4500_P150 [Compatibility Mode]

PowerPoint Presentation

Identification of Degradation Products of Simvastatin

Fast and simultaneous analysis of ethanol metabolites and barbiturates using the QTRAP® 4500 LC-MS/MS system

MRM3 Quantitation - Highest Selectivity in Complex Matrices

Microsoft Word - 3_Identification of the metabolites of tetrachloronamide by QTRAP® 4500 Complex Mass Spectrometry System_legal comments.docx

Searching QTRAP MSMS Data with Libraries in SCIEX OS-Q

Fast and Simultaneous Analysis of Ethanol Metabolites and Barbiturates in Human Urine

Highly sensitive LC-MS/MS method for the quantification of pesticides in tea matrix using the QTRAP 4500 LC-MS/MS System

High Selectivity Quantification of Protein Isoforms using MRM3 Workflow

Powerful Qual/Quant Scan Modes of QTRAP® System Technology

Analysis of Genotoxic Nitrosamines in Losartan and Ranitidine Active Pharmaceutical Ingredients

Rapid and Sensitive Analysis of a 93-Compound Forensic Panel in Urine using the QTRAP/Triple Quad 4500 LC-MS/MS System

Fast Screening Method for 86 Forensic Analytes in Human Urine

Method Development for Fake Lamb Meat Detection using SCIEX QTRAP 4500 system (CH)

Comprehensive Quantitation and Identification of Pesticides in Food Samples Using the New Eksigent ekspert ultraLC 100 and the New AB SCIEX QTRAP 4500 System

Analysis of PFAS in drinking water with EPA Method 537.1 and the SCIEX QTRAP® 4500 System

Flexible NanoSpray® III Source, for nanoflow and CESI applications

SCIEX QTRAP 4500 LC-MS/MS System Compendium of food testing applications

Quantitation of Aflatoxin M1 in Milk using SCIEX QTRAP® 4500 LC-MS/MS System

Cannabis for Per Se Law Testing in Whole Blood using theSCIEX Triple Quad QTRAP 4500 LC-MS/MS System

MassSpectator - Food Safety Edition

Nitrosamine Disinfection Byproducts in Drinking Water, LC-MS

Identification and Quantification of Designer Drugs in Urine by LC-MS/MS

Microsoft Word - Loratadine tech note 29Sep2017.docx

AB SCIEX LC-MS/MS Analysis of Emerging Food Contaminants - Quantitation and Identification Acrylamide in Starch-Rich Food

Resolution of Ether- and Diacyl-Linked Phospholipids by DMS

Higher Confidence in Identification with QTRAP_AB SCIEX.docx

Extending Metabolome Coverage-untargeted Metabolomic Workflows

Allerges_vMethod_TechNote_newTemplate_vApril27-2016-v4_sp

CYP4500 Protein Assay - Human Induction Kit Extended Panel

Simple and Robust LC-MS/MS Method of Phosphatidylethanol (PEth) in Whole Blood Using Luna® Omega Polar C18 Column

Quantification of Major Metabolites of K2 in Human Urine

Amlodapine Bioanalysis v10.docx

AB SCIEX Rapid Quantitation and Identification of Carbendazim in Orange Juice using LC-MS/MS

High Throughput Automated Sample Preparation and Analysis Workflow for Comprehensive Forensic Toxicology Screening using LC/MS/MS

Análisis Rápido de Nitrosaminas Genotóxicas por HPLC-MS/MS

Solución total QTRAP en Espectrometría de Masas en la detección de aditivos en 68 productos para la Salud comunmente usados en China

Microsoft Word - FINAL CF1836_RUO-MKT-02-2173-A_Automation Ethanol Metabolites in Urine.docx

Dont miss Synthetic Drug Present in Sample

Identification and Quantitation of Poisonous Alkaloids in Blood by SCIEX QTRAP

Determination of 6 Catecholamines in Human Plasma Samples by SCIEX Liquid Chromatography-Tandem Mass Spectrometry

Determination of Nitrofuran Metabolites in Animal-derived Food

Quantification of Dopamine, Epinephrine, Norepinephrine in Human Plasma by SCIEX Liquid Chromatography-Tandem Mass Spectrometry

SCIEX LC-MS-MS Application Technology on Origin Identification of Dairy Products based on Alpha-lactalbumin and Beta-lactoglobulin

Determination of Six Antiepileptic Drugs in Serum by SCIEX Triple Quad System (ZH)

Quick Determination of 105 Doping in Animal derived Food by QTRAP System

Rapid Determination of 41 Primary Aromatic Amines in Water

Determination of Aflatoxins B and G in Grain

A Rapid Screening and Quantitative LC-MS-MS Method of 189 Veterinary Drug Residues in Animal Food by Triple QuadTM 3500

LC-MS-MS Method for Determination of 523 Pesticide Residues in Traditional Chinese Medicine

Determination of Nitro-PAH in River Water

The Solution of Analysis 13 Nitrosamines in Drinking Water by LC-MS-MS

Determination of Six Antipsychotic Drugs in Serum by SCIEX Liquid Chromatography-Tandem Mass Spectrometry

Determination of Plant Hormones in Plants by Liquid Chromatography Tandem Mass Spectrometry

Establish a rapid and efficient method for the determination of nitrosamines in cosmetics and personal care products

Determination of Chloramphenicol Thiamphenicol and Florfenicol Residues in Fish

Determination of Tetracycline Antibiotic Residues in Animal-derived Food

QuEChERS LC-MS-MS Solutions for Detecting Carbamate Pesticides in Soils

Quantification of 74 Prohibited Hormones in Cosmetics Using LC-MS-MS System

Application of LC-MS/MS in Chinese Pharmacopoeia

Determination of Liposoluble Vitamins in Micro Blood Samples by SCIEX Liquid Chromatography Tandem Mass Spectrometry

Quantitative Analysis of Fentanyl and Analogues in Human Whole Blood

Identification of clonidine hydrochloride metabolites in pig feces using QTRAP mass spectrometry and LightSight software

Determination of Sulfonamide Residues in Chicken

Determination of Malachite Green and Crystal Violet Residues in Fish

The Application Solution for Determination of Minoxidil and Other 6 Kinds of Components in Cosmetics by LC-MS-MS Method

Determination of Linezolid and Fluconazole in Plasma by SCIEX Liquid Chromatography-Tandem Mass Spectrometry (ZH)

SCIEX Triple Quad™ 3500系统快速检测 (S)-3-氨基-1, 2-丙二醇 原料药中的 (S)-1-氨基-3-氯-2-丙醇盐酸盐杂质

The Determination of Zearalenone in Traditional Chinese Medicines using LC-MS/MS

Determination of Three Free Polyamines in Biological Samples by Using Dansyl Chloride Derivatization

Determination of Aristolochic Acid I in Longdan Xiegan Pills on SCIEX Triple QuadTM 3500 system

SCIEX Triple Quad™ 4500系统快速检测利福平和利福喷丁中两 种亚硝胺类杂质

Rapid Determination of Three Genotoxic Impurities in Linezolid by SCIEX Triple QuadTM 4500 System

Rapid Determination of 5-(4’-(azidomethyl)-[1,1’-biphenyl-2yl]-1H-tetrazole Impurity in Sartan drugs by SCIEX Triple QuadTM 4500 System

Determination of ten common additives in plastic packaging materials by LC-MSMS

Application of SCIEX 3500 triple quadrupole liquid chromatography mass spectrometry platform for the detection of 30 prohibited pesticides and their metabolites in Chinese herbal medicines and decoction pieces

Determination of 8 metabolites on main pathways of Dopamine(DA) biosynthesis and metabolism by SCIEX Triple Quad®

Determination of 1-methyl-4-aminopiperazine in Rifampicin by SCIEX Triple Quad™ 3500 LC-MS/MS system

SCIEX 液相色谱串联质谱法对水稻中220种代谢物进行靶标代 谢组学分析

SCIEX 液相色谱串联质谱法对小麦苗中183种代谢物进行靶标 代谢组学分析

Development of a High Coverage metabolomics method of Ipomoea batatas (L.) Lam by SCIEX QTRAP® System

Determination of Beta-agonist Residues in Meat

Rapid Screening and Quantification of 223 Illegal Drug Residue in Feed Using LC-MS/MS (ZH)

Rapid Screening of Phenyl-sulfonate Ester Genotoxic Impurities by pMRM-IDA-EPI

Determination of 23 Phthalate Esters in Drinking Water By LC-MS-MS

Determination of Quinolone Residues in Animal-derived Food

Determination of Animal Species Origin from Blood Products by LC-MS-MS

Determination of Five Antibiotics and their Metabolites in Serum by SCIEX LC-MS/MS

Determination of Genotoxic Impurities Methyl Methanesulfonate and Ethyl Methanesulfonate on SCIEX Triple QuadTM 4500 system

Determination of 23 Phthalate Esters in Cosmetics By LC-MS-MS

Simultaneous Determination of 331 pesticides and metabolites Residues in foods of plant origin by High Performance Liquid Chromatography-Mass Spectrometry

Simultaneous Determination of Isothiazolinone fungicides in Cigarette accessories by LC-MS /MS

SCIEX QTRAP®质谱对食品中63种添加剂的检测方案

SCIEX QTRAP®质谱对保健食品中西布曲明等33种降脂减肥类非法添加药物的检测方案

Simultaneous Determination of three kind of Chloramphenicols by LC-MS /MS

LC-MS/MS Method for Quantification of Iminoctadine tris(albesilate) in Fruits

Simultaneous Determination of 4 Kinds of Bisphenol A analogs in Drinking water by High Performance Liquid Chromatography-Mass Spectrometry

Simultaneous 23 sensitized carcinogenic stains by LC-MS /MS

Simultaneous Determination of Perchlorate and Chlorate in drinking water by LC-MS /MS

Simultaneous Determination of Perchlorate and Chlorate by LC-MS /MS

SCIEX QTRAP Mass Spectrometry for Rapid Detection of 90 Illegal Additives such as Sildenafil and Sildenafil Analogs in Health Care Products

Determination of roxarsone in animal feeds using solid-phase extraction coupled with high performance liquid chromatography-tandem mass spectrometry

Determination of Bongkrekic Acid in Rice Noodles and Tremella on SCIEX Triple QuadTM 4500 System

Determination of Malachite Green and Crystal Violet Residues in Fish

Online SPE- SCIEX Triple Quad™ 4500系统对污水中12种毒品及代谢物的定性与定量分析

The Application of Multiple Heart-Cutting 2D-LC- X500B in the Analysis of Drug Impurities in Proinsulin (ZH)

A Solution for the Determination of Perfluorinated Compounds(PFCs) in Drinking Water by Direct Injection with Triple QuadTM 3500

Analysis of 56 Perfluorinated and Polyfluorinated Compounds in Drinking Water by LC-MS/MS

快速测定土壤和沉积物中38种初级芳香胺化合物

A Solution for the Determination of Organic Contaminants in Drinking Water, Ground Water and Surface Water by Direct Injection with SCIEX Triple QuadT 3500 System

应用LC-MS/MS快速分析化妆品中10种α-羟基酸

Simultaneous Determination of Microcystins in Water by LC-MS MS

Determination of catecholamines and their metabolites in human urine using 3200MD LC-MS/MS

SCIEX Tandem Mass Spectrometry Method for Quantification of Chondroitin Sulfate and Dermatan Sulfate by Methanolysis Derivatization

Simultaneous Determination of Plasma Aldosterone, Renin Activity and Angiotensin II from Human Plasma Using LC-MS/MS

Quantification of Arginine, Homoarginine, Asymmetrical Dimethylarginine and Symmetric Dimethylarginine in Human Serum by SCIEX Liquid Chromatography-Tandem Mass Spectrometry

Simultaneous Determination of Linezolid, Voriconazole, Imatinib, Dasatinib, Nilotinib, Dabigatran Etexilate and Rivaroxaban in Plasma by SCIEX LC-MS/MS

Determination of trace angiotensin II in plasma with SCIEX Triple Quad 4500 LC-MS/MS system (ZH)

Determination of 13 Bile Acids in Serum by SCIEX Liquid Chromatography-Tandem Mass Spectrometry

Determination of 8 Polar Pesticides and metabolites in Plasma and Urine Without Derivatization (ZH)

Characterization and Identification of flavonoids in Traditional Chinese Medicine Artemisia rupestris L by SCIEX QTRAP 4500

Simultaneous Determination of Aldosterone and Angiotensin I from Human Plasma Using LC-MS/MS (ZH)

Rapid Determination of Hexabromocyclododecane and Tetrabromobisphenol A in Water

Simultaneous Determination of 4 Kinds of Chemical Medicines Illegally Added in Slimming Food by High Performance Liquid Chromatography-Mass Spectrometry

白酒类饮料中9种甜菊糖苷的液质快速检测方法

Quantitative Analysis of 12 Halogenated carboxylic acids in Tap Water by Triple QuadTM 3500

基于SCIEX三重四极杆质谱系统对食品接触材料中丙烯酰胺迁移量的测定

SCIEX QTRAP Mass Spectrometry for Rapid Detection of Seven Sweeteners in Liquor

Simultaneous Determination of 8 Kinds of Chemical Medicines Illegally Added in Traditional Chinese Medicines and Health Care Products by High Performance Liquid Chromatography-Mass Spectrometry

LC-MS/MS法快速测定动物源食品中205种兽药的完整解决方案

QTRAP®质谱系统在化合物筛查中的工作流程

Analysis Procymidone in Allium tuberosum Rottler ex Spreng by LC-MS/MS

The Application of Analysis 13 Haloamides in Drinking Water by LC-MS-MS

Determination of Genotoxic Impurities N-nitroso-N-methyl-4-aminobutyric acid on SCIEX Triple QuadTM 4500 system

Identification of Carbamate Pesticide Metabolites in Soil with LightSight Software Combined with QTRAP System

The solution for amantadine, rimantadine and ribavirin residues in animal-derived foods by LC-MS /MS

Determination of Aflatoxins B&G in Grain

Quantitative Analysis of Nine Haloacetic Acids in Water Environment by X500R QTOF System (ZH)

LC-MS-MS Method for Rapid Determination of 30 Forbidden Pesticides In Traditional Chinese Medicine

The Application Solution for Determination of Fluconazole and other 8 Kinds of Components in Cosmetics by LC-MS-MS Method

Determination of Tetracycline Antibiotic Residues in Animal-derived Food

Analysis of Six Organotin Compounds in Food package Material by LC-MS-MS

Determination of NMDA in Ranitidine Hydrochloride by LC-MS-MS

The application of 2D-LC-QTRAP in the analysis of drug impurities CN

A Rapid Screening and Quantification Method of Forbidden and Restricted Pesticides in Traditional Chinese Medicine by LC-MS-MS

Simultaneous Determination of 14 Paralytic Shellfish Toxins in Seafood using LC-MS-MS

Determination of Nitrofuran Metabolites in Animal-derived Food

Analysis 106 Compounds in Cell Supernatant by Using LC-MS-MS

Determination of Phenoxy Carboxylic Acids Herbicide in Water by LC-MS-MS

Determination of Caspofungin Posaconazole Voriconazole N-Oxide and Voriconazole in Plasma by SCIEX Liquid Chromatography-Tandem Mass Spectrometry

Identification and Quantitation of Fentanyl and Analogues in One Injection by SCIEX QTRAP

A Rapid Quantitative Method of LC-MS /MS for Dichlorvos in Sea Cucumbers (ZH)

The power of SCIEX Triple Quad liquid chromatography tandem mass spectrometry to detect polycystic ovarian syndrome related androgen (ZH)

Improving Sensitivity for Trace Pesticides Residues Quantification in Drinking Water using Trap-Elute MicroLC-MS with Large Volume Sample Loading

Determination of Monohydroxylated PAH in River Water

Determination of Chloramphenicol Thiamphenicol and Florfenicol Residues in Fish

Determination of seven Antineoplastic and antibacterial drugs in Serum by SCIEX LC-MS/MS

Simultaneous Determination of 7 Kinds of Local Anesthetics in Cosmetics by High Performance Liquid Chromatography-Mass Spectrometry (ZH)

SCIEX LC-MS-MS Application Technology on Quantitation of Lactoferrin in Dairy Products

Simultaneous quantitative analysis of metronidazole and chloramphenicol in chicken by SCIEX LC MS-MS

Simultaneous determination of five cytarabine metabolites and analogs with SelexION Ion mobility Mass Spectrum (ZH)

Detection of Methylmalonic Aciduria by Ion Chromatography Tandem Mass Spectrometry (ZH)

Determination of Quinolone Residues in Animal-derived Food

Method establishment of medium and long chain acyl-coenzyme A in biological samples

Techniques and solutions for forensic drug screening: an interview with Timothy Fassette

Forensic Compendium

The growing problem of NPS

Challenges of screening and identifying NPS in the forensic laboratory

Harnessing the power of mass spectrometry for early novel psychoactive substances (NPS) detection

Detecting novel psychoactive substances - the workflow

Overcoming NPS screening challenges in the forensic laboratory

Approaches to drug screening using Triple Quadrupole, QTRAP and QTOF technologies

Detecting and identifying NPS: a brief history

Streamlining forensic laboratory informatics for NPS screening and quantification

Novel Psychoactive Substances - Infographic

The age of novel psychoactive substances

Compruebe y maximice la calidad de sus productos agriculturales

The LC-MS/MS Workhorse SCIEX 4500 Series Mass Spectrometers

Nitrosamines impurity analysis using SCIEX QTRAP® 4500 LC-MS/MS System

Determination of Beta-agonist Residues in Meat

List of Published Articles of Therapeutic Drug Monitorings (TDM) with SCIEX LC-MS/MS System (Volume 2)

List of Published Articles on Quantitative Methods of Clinical Diagnostics/Lab-Developed Tests (LDTs) with SCIEX LC-MS/MS System

Catalogue of Literatures on target lipidomics using Triple Quad QTRAP mass spectrometry (Volume 1)

Catalogue of Literatures on Metabolomics using SCIEX mass spectrometry (Volume 1)

List of Published Articles of Therapeutic Drug Monitorings (TDM) with SCIEX LC-MS/MS System (Volume 3)

SCIEX中国药典新规定的完整解决方案

List of Published Articles with SCIEX LC-MS-MS System-Clinical-Volume 4

Determination of Sulfonamide Residues in Chicken

LC-MS/MS 技术平台

Folder for The Flyers of Food Safety Monitoring Holistic Solution

List of Published Articles with SCIEX LC-MS-MS System-Clinical-Volume 3

List of Published Articles with SCIEX LC-MS-MS System-Clinical-Volume 2

List of Published Articles of Therapeutic Drug Monitorings (TDM) with SCIEX LC-MS/MS System (Volume 4)

Catalogue of Literatures on untarget lipidomics using SCIEX high resolution mass spectrometry (Volume 1)

Catalogue of Literatures on Traditional Chinese Medicine (Volume 1)

List of Published Articles of Therapeutic Drug Monitorings (TDM) with SCIEX LC-MS/MS System (Volume 1)

Quantitation on the SCIEX QTRAP 4500 LC-MS/MS System with the ExionLC AD System

Food-Fraud-Authenticity

Aflatoxins in Milk

4500 Series of Instruments System User Guide (DE)

4500 Series of Instruments System User Guide (EN)

4500 Series of Instruments System User Guide (ZH)

Instrument Front-End Cleaning Procedure For Customers

4500 Series of Instruments System User Guide (KR)

4500 Series of Instruments System User Guide (IT)

4500 Series of Instruments System User Guide (ES)

4500 Series of Instruments System User Guide (FR)

4500 Series of Instruments System User Guide (PT)

4500 Series of Instruments System User Guide (JA)

Mometasone

Nitrosamines Flyer (PT)

SCIEX vision Journal Issue 4

Its a Triple Quadrupole and so much more

Quantify NDMA using the SCIEX QTRAP 4500 LC-MS/MS System

Ion Source Tests, Specifications, and Data Log For SCIEX Triple Quad Systems (PT)

Ion Source Tests, Specifications, and Data Log For SCIEX Triple Quad Systems (FR)

Ion Source Tests, Specifications, and Data Log For SCIEX Triple Quad Systems (KR)

Ion Source Tests, Specifications, and Data Log For SCIEX Triple Quad Systems (ZH)

Ion Source Tests, Specifications, and Data Log For SCIEX Triple Quad Systems (EN)

Ion Source Tests, Specifications, and Data Log For SCIEX Triple Quad Systems (DE)

Ion Source Tests, Specifications, and Data Log For SCIEX Triple Quad Systems (IT)

Ion Source Tests, Specifications, and Data Log For SCIEX Triple Quad Systems (JA)

Ion Source Tests, Specifications, and Data Log For SCIEX Triple Quad Systems (ES)

利用SCIEX 液相色谱串联质谱法对细胞中的能量代谢物进行靶向分析

SCIEX VISION 2021 - Vishwottam Kandikere Interview - Syngene

LC-MS/MS快速检测面粉中恩镰孢菌素及白僵菌素

SCIEX LC-MS/MS系统检测厄贝沙坦药物中4’-(叠氮甲基)-[1,1’-联苯]-2-氰基杂质(AZBC)

LC-MS/MS快速检测食品中展青霉素

厄贝沙坦制剂中叠氮类基因毒性杂质5-[(4’-(叠氮甲基)[1,1’-联苯]-2-基] -2H-四氮唑(MB-X)的定量分析检测

如何排查和解决残留和污染问题

基于SCIEX LC-MS/MS系统对血浆中多粘菌素E1和E2检测

LC-MS/MS快速检测畜禽类兽药残留

LC-MS/MS快速检测水产类农兽药残留

LC-MS/MS快速检测牛奶中兽药残留

丹磺酰氯衍生化法检测生物样品中3种游离态多胺(腐胺,精胺和亚精胺)

基于SCIEX三重四极杆质谱系统对生活饮用水中丙烯酰胺残留量的测定

基于SCIEX QTRAP®系统对毒蘑菇中6种蘑菇毒素的检测方案

动物源性食品中五氯酚残留量的LC-MS/MS定量分析检测

LC-MS/MS快速检测生活饮用水中农药残留

LC-MS/MS快速检测蜂蜜及蜂蜜产品类兽药残留

茄科蔬菜中龙葵毒素类化合物的LC-MS/MS定量分析检测

LC-MS/MS快速检测动物尿液兽药残留

基于SCIEX LC MS/MS系统衍生法对人体血浆及粪便样本9种短链脂肪酸检测

SCIEX LC-MS/MS系统快速定量饮用水中4种氯酚类化合物

Syllabus for eLearning path

SCIEX LC-MS/MS系统快速定量测定饮用水中5种微囊藻毒素

Software