The LC-MS/MS workhorse, intelligently re-engineered

QTRAP 4500 system

Known as the LC-MS/MS workhorse, this is the intelligently re-engineered design of the 4000 QTRAP platform, and sets a new benchmark for robust quantitation and library searching.

The system is ideal for laboratories requiring ultimate robustness, ruggedness, and reliability for high-throughput screening of many compounds in many samples every day.

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Key Features

Mass range

Triple quadrupole: 5 – 2,000 Da. linear ion trap: 50 - 2,000 Da

Flexible ionization options

Options include electrospray ionization (ESI) and heated nebulizer ionization probes.

Polarity switching

50 msec in MRM and Scheduled MRM modes

Detector type

AcQuRate pulse counting CEM

Features

Turbo V ion source, pulse counting detector

Scan types

Q1 MS, Q3 MS, product ion, precursor ion, neutral loss or gain, MRM, EMS, EPI, ER, MS3, MRM3, TripleTrap scanning

Ionization sources

Turbo V ion source housing with TurboIonSpray probe or APCI probe (max temp: 750ºC)

ESI flow rate range: 5 μL/min to 3 mL/min

APCI flow rate range: 200 µL/min to 3 mL/min

Cutting edge and reliable technology

The best of both

Maximize uptime with a system that can handle even the most difficult matrices with ease. Includes legendary Turbo V ion source, QJet ion guide design, and the ultimate pulse counting detector.

Turbo V ion source

This legendary source provides high-sensitivity analysis over a wide range of flow rates with quick-change APCI and TurboIonSpray probes.

QJet ion guide

The innovative design yields excellent ion containment and operates at high pressure, providing better collisional focusing to enhance ion transmission for ultimate sensitivity.

AcQuRate pulse counting detector

The detector technology works in combination with a pulse overlap correction algorithm, enabling more accurate and precise ion detection over a wide dynamic range.

List of Published Articles on Quantitative Methods of Clinical Diagnostics/Lab-Developed Tests (LDTs) with SCIEX LC-MS/MS System

Microsoft Word - 3_Identification of the metabolites of tetrachloronamide by QTRAP® 4500 Complex Mass Spectrometry System_legal comments.docx

Comprehensive Quantitation and Identification of Pesticides in Food Samples Using the New Eksigent ekspert ultraLC 100 and the New AB SCIEX QTRAP 4500 System

AB SCIEX LC-MS/MS Analysis of Emerging Food Contaminants - Quantitation and Identification Acrylamide in Starch-Rich Food

High Throughput Automated Sample Preparation and Analysis Workflow for Comprehensive Forensic Toxicology Screening using LC/MS/MS

Análisis Rápido de Nitrosaminas Genotóxicas por HPLC-MS/MS

Solución total QTRAP en Espectrometría de Masas en la detección de aditivos en 68 productos para la Salud comunmente usados en China

Quantification of Dopamine, Epinephrine, Norepinephrine in Human Plasma by SCIEX Liquid Chromatography-Tandem Mass Spectrometry

SCIEX LC-MS-MS Application Technology on Origin Identification of Dairy Products based on Alpha-lactalbumin and Beta-lactoglobulin

Rapid Determination of 5-(4’-(azidomethyl)-[1,1’-biphenyl-2yl]-1H-tetrazole Impurity in Sartan drugs by SCIEX Triple QuadTM 4500 System

Determination of ten common additives in plastic packaging materials by LC-MSMS

Application of SCIEX 3500 triple quadrupole liquid chromatography mass spectrometry platform for the detection of 30 prohibited pesticides and their metabolites in Chinese herbal medicines and decoction pieces

Determination of Genotoxic Impurities Methyl Methanesulfonate and Ethyl Methanesulfonate on SCIEX Triple QuadTM 4500 system

Simultaneous Determination of 331 pesticides and metabolites Residues in foods of plant origin by High Performance Liquid Chromatography-Mass Spectrometry

Simultaneous Determination of 4 Kinds of Bisphenol A analogs in Drinking water by High Performance Liquid Chromatography-Mass Spectrometry

SCIEX QTRAP Mass Spectrometry for Rapid Detection of 90 Illegal Additives such as Sildenafil and Sildenafil Analogs in Health Care Products

Determination of roxarsone in animal feeds using solid-phase extraction coupled with high performance liquid chromatography-tandem mass spectrometry

A Solution for the Determination of Perfluorinated Compounds(PFCs) in Drinking Water by Direct Injection with Triple QuadTM 3500

A Solution for the Determination of Organic Contaminants in Drinking Water, Ground Water and Surface Water by Direct Injection with SCIEX Triple QuadT 3500 System

SCIEX Tandem Mass Spectrometry Method for Quantification of Chondroitin Sulfate and Dermatan Sulfate by Methanolysis Derivatization

Quantification of Arginine, Homoarginine, Asymmetrical Dimethylarginine and Symmetric Dimethylarginine in Human Serum by SCIEX Liquid Chromatography-Tandem Mass Spectrometry

Protein G 富集联合 LC-MS/MS 同时测定人血清中三种抗体类生物药

Protein G富集联合LC-MS/MS同时测定人血清中八种抗体类生物药

Simultaneous Determination of Linezolid, Voriconazole, Imatinib, Dasatinib, Nilotinib, Dabigatran Etexilate and Rivaroxaban in Plasma by SCIEX LC-MS/MS

Characterization and Identification of flavonoids in Traditional Chinese Medicine Artemisia rupestris L by SCIEX QTRAP 4500

Simultaneous Determination of Aldosterone and Angiotensin I from Human Plasma Using LC-MS/MS (ZH)

Rapid Determination of Hexabromocyclododecane and Tetrabromobisphenol A in Water

Simultaneous Determination of 4 Kinds of Chemical Medicines Illegally Added in Slimming Food by High Performance Liquid Chromatography-Mass Spectrometry

Simultaneous Determination of 8 Kinds of Chemical Medicines Illegally Added in Traditional Chinese Medicines and Health Care Products by High Performance Liquid Chromatography-Mass Spectrometry

The Application Solution for Determination of Fluconazole and other 8 Kinds of Components in Cosmetics by LC-MS-MS Method

A Rapid Screening and Quantification Method of Forbidden and Restricted Pesticides in Traditional Chinese Medicine by LC-MS-MS

Determination of Caspofungin Posaconazole Voriconazole N-Oxide and Voriconazole in Plasma by SCIEX Liquid Chromatography-Tandem Mass Spectrometry

Identification and Quantitation of Fentanyl and Analogues in One Injection by SCIEX QTRAP

A Rapid Quantitative Method of LC-MS /MS for Dichlorvos in Sea Cucumbers (ZH)

The power of SCIEX Triple Quad liquid chromatography tandem mass spectrometry to detect polycystic ovarian syndrome related androgen (ZH)

Improving Sensitivity for Trace Pesticides Residues Quantification in Drinking Water using Trap-Elute MicroLC-MS with Large Volume Sample Loading

Simultaneous Determination of 7 Kinds of Local Anesthetics in Cosmetics by High Performance Liquid Chromatography-Mass Spectrometry (ZH)

Software

Name	File Size	Release Date	Release Notes	Download
MasterView 1.1 Software	560MB	12.01.14	Release Notes	Download
PeakView 2.0 Software	569 MB	01.01.14	Release Notes	Download
PeakView 2.1 Software	537 MB	01.01.14	Release Notes	Download
MasterView 1.0 Software	1.5 GB	12.01.13	Release Notes	Download
MRM3 Optimization for Analyst 1.5.1 Software	1.6 MB	12.01.13	Release Notes	Download
Analyst 1.6.2 Software	445 MB	06.01.13	Release Notes	Download
Analyst 1.6.1 Software	423 MB	03.01.12	Release Notes	Download
Analyst 1.5.1 Software	316 MB	06.01.10	Release Notes	Download

All software downloads

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