DNA 20 kb Plasmid and Linear Kit Application Guide
Instructions for sample preparation using the DNA 20 kb Plasmid and Linear Kit, with instructions for data acquisition and data analysis on the BioPhase 8800 system. Includes instructions for data acquisition with the BioPhase 8800 Driver for Empower™
One-platform strategy for comprehensive characterization of the bispecific antibody, emicizumab, using the BioPhase 8800 system
Significantly shorten the timeline for assay development while achieving comprehensive characterization of size and charge variants of bispecfic monoclonal antibodies (mAbs) using a multi-capillary platform.
Monoclonal antibody CE-SDS purity analysis with the SCIEX low pH SDS sample buffer on the BioPhase 8800 system
Greatly reduce sample processing and analysis time, and achieve excellent CE-SDS repeatability and intermediate precision results based on the IgG profiling of three different biosimilars for drozitumab, infliximab, and adalimumab using the BioPhase 8800 system.
Lightning capillary electrophoresis sodium dodecyl sulfate (CE-SDS) workflow for high-throughput analysis of biotherapeutics
Explore a highly robust CE-SDS workflow with excellent intermediate precision, accuracy and no carryover or loss of separation efficiency that is 1.5 times faster than the SCIEX original CE-SDS workflow.
A new approach for high-resolution full and empty AAV capsid analysis utilizing a high-throughput method for comprehensive AAV evaluation on a single CE platform
Discover how to save time and cost while reducing laboratory footprint when analyzing multiple AAV critical quality attributes using a single, mutli-capillary platform.
Characterization of lentiviral vector quality attributes using capillary electrophoresis (CE) platform technology
Mitigate the technical difficulties in characterizing lentiviral vectors for the assessment of multiple quality attributes through a CE platform-based approach.
A design of experiment (DoE) approach to facilitate capillary isoelectric focusing method development for Hemlibra
Significantly reduce the method development time from weeks to 1 day using a multifactorial DoE approach to facilitate high-speed cIEF method optimization for the bispecfic humanized monoclonal antibody, Hemlibra.
High-throughput, highly reproducible RNA analysis on the BioPhase 8800 system using the Empower Chromatography Data System (CDS)
Discover how to perform high-throughput and highly reproducible RNA analyses in a compliant environment using the BioPhase 8800 driver for Empower software and the RNA 9000 Purity & Integrity kit.
Separation of circular RNA from the linear precursor by multi-capillary electrophoresis
Achieve rapid separation of circular RNA species using a high resolution mRNA analysis kit and a high-throughput electrophoresis system.
mRNA-LNP nucleic acid assessment from distinct formulations by multi-capillary gel electrophoresis
Learn how you can easily achieve robust characterization for in vitro transcribed mRNA utilized for mRNA-LNP synthesis using the BioPhase 8800 system and RNA 9000 Purity & Integrity kit
BioPhase 8800 system consumables and reagents catalog
Fast Glycan Labeling and Analysis kit application guide
Instructions for sample preparation using the Fast Glycan Labeling and Analysis kit and for data acquisition and analysis using BioPhase software on the BioPhase 8800 system.
BioPhase CE-SDS Protein Analysis kit
Get instructions for sample preparation and data analysis when using the BioPhase CE-SDS Protein Analysis kit.
RNA 9000 Purity & Integrity kit
Get instructions for sample preparation and data analysis when using the RNA 9000 Purity & Integrity kit on the BioPhase 8800 system.
BioPhase Capillary Isoelectric Focusing (cIEF) kit
Get instructions for sample preparation and data analysis when using the BioPhase Capillary Isoelectric Focusing (cIEF) kit
High-resolution characterization of both sgRNA and Cas9 mRNA in a single analysis for CRISPR/Cas9 applications
Discover an efficient and time-saving workflow to assess various critical quality attributes (CQAs) for potential mRNA vaccines and CRISPR reagents using the BioPhase 8800 system and the RNA 9000 Purity & Integrity kit.
Genome integrity analysis of adeno-associated viruses (AAVs)
Evaluate the genome integrity and purity of AAVs irrespective of their serotype in a high-throughput format using the RNA 9000 Purity & Integrity kit with the BioPhase 8800 system. Discover the benefits of high sensitivity and excellent inter-capillary reproducibility.
High-throughput multi-capillary SDS gel electrophoresis of proteins
The BioPhase 8800 system utilizes a multi-capillary format to provide high-throughput sodium dodecyl sulfate capillary gel electrophoresis (SDS-CGE) of proteins, enabling characterization to be performed on multiple samples in parallel and shortening development time.
Acceleration of method optimization for AAV capsid purity analysis using multi-capillary electrophoresis platform
The ability to perform eight separations in parallel on the BioPhase 8800 system allows for faster processing of samples and overall increased throughput to accelerate method development for adeno-associated viruses (AAVs).
BioPhase 8800 System 21 CFR Part 11 compliance
The BioPhase 8800 system software has the design and features to meet the 21 CFR Part 11 compliance and regulatory requirements for operation.
Rapid and reproducible parallel processing of charge heterogeneity analysis of protein therapeutics by multi-capillary isoelectric focusing
The BioPhase 8800 system offers a solution to the limited throughput that current single-capillary cIEF systems provide. The new multi-capillary system enables parallel isoelectric focusing analysis for up to 8 samples at a time, allowing for rapid charge heterogeneity analysis of protein therapeutics.
Amplification-free analysis of lentiviral vector genome integrity on BioPhase 8800 system
Accelerate analysis time and potentially speed up lentiviral vector (LV)-related product development processes for gene therapy with high-throughput genome integrity analysis of multiple LVs simultaneously on the BioPhase 8800 system.
CE-SDS analysis of Etanercept using BioPhase 8800 system
Accelerate method development for protein analysis with the multi-capillary separation on the BioPhase 8800 system by simultaneously analyzing multiple Etanercept samples prepared under different conditions and assessing the consistency of deglycosylation reactions in other lots.
Reproducibility study of a high-throughput released N-glycan workflow
This technical note demonstrates the robustness and consistency of the high-throughput analysis of APTS-labeled N-linked glycans by capillary electrophoresis (CE) with laser-induced fluorescence (LIF) detection. The inter- and intracapillary reproducibility validation using the BioPhase Fast Glycan Labeling and Analysis kit yielded 576 data points from 2 instruments, 2 cartridges and 3 chemistry kits.
Released N-linked glycan analysis employing automated sample preparation on a Biomek i5 liquid handler
This technical note presents a streamlined N-linked glycan analysis that employs an automated sample preparation with the magnetic bead-mediated glycan workflow followed by capillary electrophoresis (CE). The inter- and intra-capillary reproducibility results demonstrate the robustness of the assay with automated sample preparation.
High-throughput released N-glycan identification using CE and a customizable glycan library
This technical note demonstrates the procedures for a highthroughput N-linked glycan identification using the new BioPhase Fast Glycan Labeling and Analysis kit with the BioPhase 8800 system. This kit allows customers to achieve large-scale N-glycan profiling with streamlined sample preparation. The user-friendly BioPhase 8800 software empowers customers to customize molecule-specific glycan libraries, which can be employed in a platform separation method.
Application guide
Protein purity
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