The Power of Precision
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Advance your research with front-end
instruments designed to help you realize the full power of your mass
spectrometer. SCIEX has the broadest portfolio of ESI-MS front-ends
can facilitate various flow rates, sample requirements and
sensitivities. No one else offers the entire range
flow, microflow, nanoflow LC-MS and even ultra-low flow
ExionLC 2.0 series
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Differential mobility spectrometry (DMS) and
ion mobility spectrometry are analytical techniques used to separate
ions based on their gas phase mobility. Multiple types of ion
devices exist, such as drift tubes, traveling wave, and high-field
asymmetric waveform devices. Learn how you can separate yourself
Differential Ion Mobility.
The latest ion sources from SCIEX enable
enhanced sensitivity and robustness with greater desolvation range
across all MS platforms, from Triple Quad to QTRAP and QTOF.
Turbo V ion
OptiFlow Turbo V ion
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vMethod applications are pre-configured and verified LC-MS/MS
that reduce the need for method development – significantly cutting
time, effort and money to deploy a new assay. Every vMethod provides
method conditions, recommended sample prep, LC and MS conditions,
details for applicable MS/MS library databases for key applications.
and personal care products (PPCPs)
and protein bioanalysis
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Analyst TF software
Biologics explorer software
Molecule profiler software
High resolution and QTRAP
libraries can dramatically enhance the quality of your analysis,
you much improved confidence in your data. With a comprehensive
at your fingertips, you can easily create methods and process
and non-targeted screening data on your complex samples, faster and
easier than ever before.
All in one
HR-MS/MS library with NIST 2017
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Boost the performance of your mass
spectrometer and improve sensitivity, productivity, and data
iChemistry Solutions are the world's only reagents and
that are custom designed with your success in mind.
RNA 9000 Purity & Integrity kit
kit for amino acid analysis of hydrolysates
kit for amino acid analysis of physiological fluids
protein digestion solution
Biologics analysis kit for
protein assay - human induction kit
CZE rapid charge variant analysis kit
glycan analysis and labeling for the PA 800 plus
standards kit for pesticide analysis
auEChERS extraction and dispersive kit
Ampliflex keto reagent
Cleavable ICAT reagent
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QTOF – Quadrupole
Time of Flight
QTRAP® – Triple Quad Linear
SWATH® – Data Independent
SelexION® – Differential
MicroLC – Microflow
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From substantiating new discoveries through
to end-to-end validated workflows for high-throughput biomarker
in the clinic, thousands of scientists worldwide depend upon mass
innovation from SCIEX to advance their work in the fields of
research, omics and diagnostics.
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How do you protect your reputation and meet today’s global food
standards? Whether you are a commercial lab or a food manufacturer,
quality of your food testing data is vital to your business. SCIEX
solutions help you meet maximum residue limits (MRLs) with
data that you can genuinely count upon. With a portfolio of
applications, your lab can quickly and easily react to diverse
Authenticity & Profiling Analysis
& Food Contact Substance Analysis
Food and Beverage Testing
How do you ensure the integrity of your
results in an industry that is never constant? By accurately
even the smallest compound angles you can deliver evidence that
SCIEX forensic analysis solutions deliver fast, highly accurate
data across a multitude of compounds and biomarkers, from the known
the new and novel.
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and SNP Analysis
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Transform the capacity and capability of your biologics pipeline
complete end-to-end solutions that make your lab more productive,
more successful. With a longstanding track record in pharma
development and manufacturing, our unparalleled application
with best-in-class hardware, software and support all integrate to
revolutionize your lab.
Native Mode Analysis
Nucleic Acid and Plasmid Analysis
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Mass Spec Operators
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The SCIEX Now Learning Hub offers the most diverse and flexible learning options available, with best-inclass content that helps you to get the most out of your instrument and take your lab to the next level. Available personalized learning paths based on the latest memory science ensure better knowledge retention, and automated onboarding and enrollment means you’ll get up and running faster.
SCIEX Now Learning Hub offers the most diverse and
flexible learning options available, with best-in-class content that
helps you to get the most out of your instrument and take your lab
the next level. Available personalized learning paths based on the
latest memory science ensure better knowledge retention, and
onboarding and enrollment means you’ll get up and running faster.
SCIEX Learning Manager provides you with the infrastructure to assign, monitor and report on your staff's
competency through a single digital platform. Effectively manage the training process for new hires, ensure
continuous staff development and access information with a single log-in to your SCIEX account.
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extensive list of training offerings. Choose from over 100
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efficient way possible. Extensive self-help resources like our deep
Knowledge Base, enable you to solve many problems on your own. SCIEX
is available 24/7 and your new SCIEX instruments are automatically
to your profile when you purchase.
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The integration of capillary electrophoresis (CE) with electrospray ionization (ESI) into a single dynamic process within the same device delivers high-efficiency electrophoretic and hydrodynamic separation at ultra-low flow rates to enhance sensitivity and quantitation while reducing ion suppression bias.
When interfaced with your mass spectrometer, CESI-MS expands the reach of your mass spectrometer by providing:
Increased Coverage from Limited Samples
CESI-MS enables multiple experiments to be generated from as little as 5 microlitres (μL) of starting material. Combining this capability with the multi-segment injection methodology, you can process ten experiments in the time it would normally take to process one, with less than 1 μL consumed.
The OptiMS cartridge assembly consists of a separation capillary terminating in the porous sprayer, a conductive liquid capillary, circulating liquid cooling, and sprayer housing. Conductive fluid is delivered automatically from a system vial that completes the CE circuit.
Located within a protective housing, the CESI 8000’s sprayer combines an intrinsically low-flow CE separation with electrospray ionization (ESI) within a single, simple device that has no liquid junction or dead volume.
The OptiMS Adapter Kit can be easily installed so you can begin acquiring CESI-MS data within minutes, utilizing our "plug-and-spray" workflow with the CESI OptiMS capillary cartridge.
CESI-MS is particularly valuable for precious samples such as: subcellular fractions, microdialysates, CSF, murine samples, CTCs, needle biopsies, FFPE archives, or highly toxic samples such as ADCs and venoms.
Electrophoretic separation combined with highly efficient ESI supports a variety of applications, from investigating the anionic and cationic metabolome, to the study of proteoforms, and multimeric protein complexes.
For deep characterization of proteoforms, charge states, and PTMs, CESI is the only front end technology that enables liquid phase high resolution separation of proteins, metal binding, and protein complexes.
Combining the high efficiency and ultra-low flow of CE with ESI greatly improves assay sensitivity while reducing ion suppression bias to see what you’ve been missing.
Discover why CESI is the method of choice for high-resolution separation of polar metabolites, peptides and proteins rich in particular post-translational modifications (such as glycosylation, citrullination, methylation, and phosphorylation).
Whether using the CESI 8000 Plus as a standalone instrument or connected to a mass spectrometer, the system allows you to see more than ever before.
Detecting Challenging Post Translational Modifications (PTMs) using CESI-MS
Intact Casein - A Model System for the Separation of Intact Phosphorylated Proteins by CESI-MS
Improving the Detection Limits for Highly Basic Neuropeptides Using CESI-MS
Expanding phosphorylation and post translational site mapping in proteomics using CESI-MS
A new approach to the analysis of anionic metabolites by CESI-MS with negative ion electrospray ionization
Watch opinion leaders, top scientists and industry innovators share how CESI-MS has helped them in their research in on-demand presentations from past symposiums.
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