AB Sciex is doing business as SCIEX. © 2010-2019 AB Sciex. The trademarks mentioned herein are the property of the AB Sciex Pte. Ltd. or their respective owners. AB SCIEX™ is being used under license. Beckman Coulter® is being used under license. Product(s) may not be available in all countries. For information on availability, please contact your local representative. For research use only. Not for use in diagnostic procedures.
Merge triple quadrupole and linear ion trap capabilities with multi-component IonDrive™ Technology to produce the world's most sensitive and selective triple quadrupole.

QTRAP 6500+ System

Merge triple quadrupole and linear ion trap capabilities with multi-component IonDrive™ Technology to produce the world's most sensitive and selective triple quadrupole.

QTRAP 6500+ System

QTRAP 6500 System ion source

QTRAP 6500 System ion source

Merge triple quadrupole and linear ion trap capabilities with multi-component IonDrive™ Technology to produce the world's most sensitive and selective triple quadrupole.
Merge triple quadrupole and linear ion trap capabilities with multi-component IonDrive™ Technology to produce the world's most sensitive and selective triple quadrupole.
QTRAP 6500 System ion source

QTRAP® 6500+ System

QTRAP® 6500+ LC-MS/MS System

High-Throughput Mass Spec

This system is the fastest and most sensitive QTRAP. It provides the best LOQs to enable the detection and quantification of the widest scope of chemical compounds in the most challenging matrices. Improved polarity switching and MRM3 speeds allow faster chromatography and better throughput. The built in QTRAP functionality enables quantitative MRMs and qualitative QTRAP scans in the same injection to maximize throughput.

The system is ideal for laboratories performing demanding applications requiring ultimate sensitivity for ultra-low level quantitation of both small and large molecules.

Status: Available

More Ions with IonDrive Technology

Key Features

Mass Range Dual switchable mass range: up to 1250 Da or up to 2000 Da
Features IonDrive QJet, HED Detector
Detector Type IonDrive High Energy Detector+
Scan Types Q1 MS, Q3 MS, Product Ion, Precursor Ion, Neutral Loss or Gain, MRM, EMS, EPI, ER, MS3, MRM3, TripleTrap™ Scanning
Ionization Sources/Options IonDrive Turbo V; OptiFlow™ Turbo V; TurboIonSpray®; Atmospheric-pressure chemical ionization (APCI); DuoSpray™, and NanoSpray® III, Phytronix LDTD, Advion LESA Clarity, Digital PicoView, NanoSource, SelexION®+

Downloads & Resources

RUO-MKT-18-2501-C

Resources
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Title Date
High-Throughput Targeted Lipidomics Analysis of Dihydroceramide Desaturase-1 (DES1) Knockout Mice 08/28/2019
Potency Analysis in Hemp and Cannabis Products 07/25/2019
Direct Sample Analysis Using TEIS Combined with Mass Spectrometry 06/29/2019
Cannabis Testing Solutions and Resources 06/19/2019
Quantitative LC-MS Solution for Targeted Analysis of Cell Culture Media 06/12/2019
AN-Hydrophilic Marine Biotoxins in Seafood 06/12/2019
Single Source Solution for Low Flow Chromatography 06/07/2019
Analysis of the Canadian Cannabis Pesticides List Using Both ESI and APCI Techniques 06/06/2019
Microflow Chromatography-Bridging the Sensitivity Gap for Quantitation of a Pyrrolobenzodiazepine Dimer 05/02/2019
User Guide: NanoSpray Ion Source Operator Guide (EN) 04/17/2019
Sub-Picogram Level Quantitation of Desmopressin in Small Volumes of Human Plasma Using a Trap-Elute MicroLC-MS System 04/17/2019
IonDrive Turbo V Ion Source Operator Guide (EN) 04/01/2019
IonDrive Turbo V Ion Source Operator Guide (FR) 04/01/2019
IonDrive Turbo V Ion Source Operator Guide (DE) 04/01/2019
IonDrive Turbo V Ion Source Operator Guide (IT) 04/01/2019
IonDrive Turbo V Ion Source Operator Guide (ES) 04/01/2019
IonDrive Turbo V Ion Source Operator Guide (JA) 04/01/2019
IonDrive Turbo V Ion Source Operator Guide (ZH) 04/01/2019
6500 and 6500+ Series of Instruments Qualified Maintenance Person Guide (EN) 03/01/2019
Ion Source Tests, Specifications, and Data Log (EN) 03/01/2019
6500 and 6500+ Series of Instruments Qualified Maintenance Person Guide (DE) 03/01/2019
6500 and 6500+ Series of Instruments Qualified Maintenance Person Guide (FR) 03/01/2019
6500 and 6500+ Series of Instruments Qualified Maintenance Person Guide (IT) 03/01/2019
6500 and 6500+ Series of Instruments Qualified Maintenance Person Guide (ES) 03/01/2019
6500 and 6500+ Series of Instruments Qualified Maintenance Person Guide (JA) 03/01/2019
6500 and 6500+ Series of Instruments Qualified Maintenance Person Guide (ZH) 03/01/2019
OptiFlow Turbo V Ion Source Operator Guide (EN) 03/01/2019
OptiFlow Turbo V Ion Source Operator Guide (DE) 03/01/2019
OptiFlow Turbo V Ion Source Operator Guide (ES) 03/01/2019
OptiFlow Turbo V Ion Source Operator Guide (FR) 03/01/2019
OptiFlow Turbo V Ion Source Operator Guide (IT) 03/01/2019
OptiFlow Turbo V Ion Source Operator Guide (JA) 03/01/2019
OptiFlow Turbo V Ion Source Operator Guide (ZH) 03/01/2019
Ion Source Tests, Specifications, and Data Log (ZH) 03/01/2019
Ion Source Tests, Specifications, and Data Log (IT) 03/01/2019
Ion Source Tests, Specifications, and Data Log (DE) 03/01/2019
Ion Source Tests, Specifications, and Data Log (JA) 03/01/2019
Ion Source Tests, Specifications, and Data Log (FR) 03/01/2019
Ion Source Tests, Specifications, and Data Log (ES) 03/01/2019
Achieving the California Pesticide Regulations in Cannabis Using Optimized APCI and ESI Techniques 02/20/2019
Parts and Equipment Guide for Ion Sources and Mass Spectrometers (EN) 02/01/2019
Parts and Equipment Guide for Ion Sources and Mass Spectrometers (DE) 02/01/2019
Parts and Equipment Guide for Ion Sources and Mass Spectrometers (ES) 02/01/2019
Parts and Equipment Guide for Ion Sources and Mass Spectrometers (FR) 02/01/2019
Parts and Equipment Guide for Ion Sources and Mass Spectrometers (IT) 02/01/2019
Parts and Equipment Guide for Ion Sources and Mass Spectrometers (JA) 02/01/2019
SCIEX 6500+ Series Mass Spectrometers - KR 01/22/2019
Analysis of the Massachusetts Cannabis Pesticides List Using the SCIEX QTRAP 6500+ System 01/22/2019
Extending the Lower Limits of Quantification of a Therapeutic Oligonucleotide Through Microflow LC-MSMS 01/22/2019
SelexION/SelexION+ Technology User Guide for SCIEX Triple Quad and QTRAP Systems (ZH) 01/15/2019
Top 5 Pesticide Challenges in Cannabis 01/03/2019
Achieve Broad Lipid Quantitation using a High-Throughput Targeted Lipidomics Method 01/03/2019
Meeting California Cannabis Testing Requirements Using SCIEX LC-MSMS 12/26/2018
SelexION/SelexION+ Technology Site Planning Guide for SCIEX Triple Quad and QTRAP Systems (ZH) 12/19/2018
Environmental Compendium Volume 3 12/10/2018
Separation of Bile Acid Isomers with Differential Mobility Spectrometry 12/03/2018
Turbo V Ion Source Operator Guide (IT) 12/01/2018
Turbo V Ion Source Operator Guide (DE) 12/01/2018
Turbo V Ion Source Operator Guide (FR) 12/01/2018
Turbo V Ion Source Operator Guide (ES) 12/01/2018
Turbo V Ion Source Operator Guide (EN) 12/01/2018
Turbo V Ion Source Operator Guide (RU) 12/01/2018
Turbo V Ion Source Operator Guide (ZH) 12/01/2018
Turbo V Ion Source Operator Guide (PL) 12/01/2018
Brochure KR: Triple Quad and QTRAP 6500+ 11/28/2018
Powerful Scan Modes of QTRAP System Technology 11/27/2018
HILIC Based LC-MS-MS for High Throughput Targeted Lipidomics 11/26/2018
Resolution of Ether and Diacyl-Linked Phospholipids by Differential ION Mobility Spectrometry (DMS) 11/19/2018
Quantification of the Therapeutic Peptide Exenatide in Human Plasma 11/08/2018
Quantitative and Qualitative Metabolomics for the Investigation of Intracellular Metabolism 10/22/2018
Ultra-Sensitive Quantification of Trastuzumab Emtansine in Mouse Plasma using Trap-Elute MicroLC-MS Method 08/10/2018
Universal Solution for Monoclonal Antibody Quantification of Biological Fluids Using Trap Elute MicroLC-MS Method 08/10/2018
Quantitation of Dicamba and Acid Herbicides in Agricultural Field Samples on SCIEX QTRAP 6500plus System 07/02/2018
Parts and Equipment Guide for Ion Sources and Mass Spectrometers (ZH) 02/01/2018
SCIEX QTRAP 6500+ and SCIEX Triple QUAD 6500+ Declaration of Conformance 12/22/2017
6500+ Series of Instruments Site Planning Guide (North America/EMEA only) 12/20/2017
6500 and 6500+ Series of Instruments Site Planning Guide (FR) 12/20/2017
6500 and 6500+ Series of Instruments Site Planning Guide (IT) 12/20/2017
6500 and 6500+ Series of Instruments Site Planning Guide (ES) 12/20/2017
6500 and 6500+ Series of Instruments System User Guide (ES) 12/20/2017
6500 and 6500+ Series of Instruments System User Guide (FR) 12/20/2017
6500 and 6500+ Series of Instruments System User Guide (IT) 12/20/2017
DuoSpray Ion Source for Triple Quadrupole and QTRAP Systems Operator Guide (IT) 12/20/2017
6500 and 6500+ Series of Instruments System User Guide (DE) 12/01/2017
Metabolomics Differentiates Classified Cancer Patients 11/16/2017
DuoSpray Ion Source for Triple Quadrupole and QTRAP Systems Operator Guide (DE) 10/10/2017
DuoSpray Ion Source for Triple Quadrupole and QTRAP Systems Operator Guide 10/01/2017
6500+ Series of Instruments Site Planning Guide (DE) 10/01/2017
Determination of Limaprost in Human Plasma 09/13/2017
Improved sensitivity for LC-MS quantitation of biologics in plasma using Trap-and-Elute MicroLC-MS 06/22/2017
Clinical applications of direct coupling of Bio-compatible SPME devices to MS via Open-Port Probe sampling interface 06/22/2017
Open-Port Probe Sampling Interface for the Direct Coupling of Solid-Phase Microextraction to Atmospheric Pressure Ionization Mass Spectrometry 06/21/2017
Robust and High Throughtput Lipid Profiling of Dry Blood Spot Samples using Automated FIA MS-MS(all) Technique 06/20/2017
QTRAP Compendium (JP) 01/10/2017
Sensitive and Accurate Quantitation of the Antibody-Drug Conjugate Ado-Trastuzumab Emtansine in Rat Plasma 01/10/2017
Quantification of 11-nor-9-Carboxy-THC and Panel of 22 Drugs in Hair using a Hybrid Triple Quadrupole Linear Ion Trap Mass Spectrometer 10/27/2016
QTRAP Compendium 10/16/2016
LC-MS/MS Analysis of Emerging Food Contaminants Detection of Glyphosate in Food Samples using QuPPe-LC-DMS-MS/MS 09/01/2016
LC-MS/MS Analysis of Emerging Food Contaminants - Trace Level Detection of Glyphosate in Water and Beer Samples 09/01/2016
Bioanalysis of β-Lactamase Inhibitors on the SCIEX QTRAP 6500+ System 09/01/2016
Measurement of a Panel of Steroids by LC-MS MS, Employing Rapid Polarity Switching Poster 08/25/2016
Target and non-target water testing: claim and reality 07/27/2016
Screening for fungal and bacterial toxins using QTRAP® technology 07/12/2016
Automated glyphosate testing in water and food samples 07/07/2016
LC-MS/MS Quantitation of Underivatized Glyphosate and Other Polar Pesticides 06/01/2016
Hair Testing using Mass Spectrometry for Forensic Applications 05/24/2016
LC-MS/MS analysis of marker compounds for sensory quality and authenticity of fruit juices 05/16/2016
Qq-TOF-technology: breakthrough in clinical toxicological analytics 05/12/2016
Qualitative and quantitative analysis of pesticides in food samples using the X500R QTOF System 05/11/2016
LC-MS/MS Determination of Vitamin D Profiles in serum after Derivatization with Amplifex Reagent 05/11/2016
User Guide: 3500, 4500, and 6500+ Systems Electromagnetic Environment Information 04/20/2016
Quantification of Peptides with Poor MS/MS Fragmentation using Novel Jet Injector SelexION® + MIM Workflow 01/31/2016
Introducing the SCIEX Triple Quad and QTRAP 6500+ LC-MS/MS System with optional SelexION Technology 10/01/2015
LC-MS/MS Analysis of Emerging Food Contaminants (6500+) 10/01/2015
LC-MS/MS Analysis of Emerging Food Contaminants (Perfluoroalkyl Acids) 10/01/2015
User Guide: PhotoSpray Ion Source Operator Guide 09/16/2015
6500 and 6500+ Series of Instruments System User Guide 09/11/2015
User Guide: DuoSpray Ion Source for Triple Quadrupole and QTRAP Systems Operator Guide (IT) 08/31/2015
User Guide: DuoSpray Ion Source for Triple Quadrupole and QTRAP Systems Operator Guide (FR) 08/31/2015
User Guide: DuoSpray Ion Source for Triple Quadrupole and QTRAP Systems Operator Guide (ES) 08/31/2015
User Guide: PhotoSpray Ion Source Operator Guide (DE) 08/31/2015
User Guide: PhotoSpray Ion Source Operator Guide (IT) 08/31/2015
User Guide: PhotoSpray Ion Source Operator Guide (FR) 08/31/2015
User Guide: PhotoSpray Ion Source Operator Guide (ES) 08/31/2015
6500+ Brochure (Triple Quad and QTRAP) 08/03/2015
User Guide: 6500 and 6500+ Series of Instruments Site Planning Guide 06/30/2015
Unlocking the Benefits of MicroLC with SCIEX and Eksigent Technology 06/17/2014
Instrument Front-End Cleaning Procedure Manual 10/01/2013
MassSpectator - Food Safety Edition
Software
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1. Mass Range

Triple quadrupole: 5 – 2,000 Da
Linear ion trap: 50 - 2,000 Da

2. Flexible Ionization Options

Options include Electrospray (ESI) ionization and heated nebulizer ionization probes.

QTRAP 6500+ System
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2
3
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3. Selective, Robust and Powerful Ion Separation

Optional SelexION®

4. Detector Type

IonDrive™ High Energy detector

5. Polarity Switching

5 msec in MRM and Scheduled MRM modes

qtrap-6500plus-intro-icontop-4col

Three Areas of Enhancements for the 6500+ Series

The production of more ions with the newly designed IonDrive™ Turbo V source is just one of the updates you will see with the QTRAP 6500+. Also added is the ability to capture and transmit more ions with the unique IonDrive™ QJet guide and greater detection with the new IonDrive™ High Energy Detector+.

IonDrive™ Turbo V Source

IonDrive Turbo V Source

The new design of the legendary Turbo V™ source increases ion production by using enhanced gas flow dynamics and optimized heater configuration to improve reliability, reproducibility, and robustness.

Learn More
IonDrive™ QJet Guide

IonDrive QJet Guide

With its dual stage design, the IonDrive QJet Guide improves sensitivity and ion capture rate while focusing ions more efficiently than funnel approaches.

Learn More
IonDrive™ High Energy Detector+

IonDrive High Energy Detector+

Pulse counting fundamentals achieve ultra sensitivity at the lower end, while increasing linearity at high count rates. The result is the collection of more ions across a broader dynamic range.

Learn More
SelexION®+ DMS Technology

SelexION®+ DMS Technology

Ideal development suite for applications requiring the separation of isobaric species, isolation of challenging co-eluting contaminants, and reduction of high background noise.

Learn More
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AB Sciex is doing business as SCIEX. © 2010-2019 AB Sciex. The trademarks mentioned herein are the property of the AB Sciex Pte. Ltd. or their respective owners. AB SCIEX™ is being used under license. Beckman Coulter® is being used under license. Product(s) may not be available in all countries. For information on availability, please contact your local representative. For research use only. Not for use in diagnostic procedures.