Differential mobility spectrometry (DMS) and ion mobility spectrometry are analytical techniques used to separate ions based on their gas phase mobility. Multiple types of ion mobility devices exist, such as drift tubes, traveling wave, and high-field asymmetric waveform devices. The SelexION technology is a small planar device that separates ions in the mobility region based on their respective size, shape, charge state, and chemical interaction, prior to entering the mass spectrometer. SelexION provides an additional dimension of selectivity which increases analytical separation power, even if compounds have identical molecular weights and chromatographic retention times. Used in pharmaceutical, academic, and food and environment testing labs across the globe, SelexION DMS technology brings the power of ion mobility to even routine users.
The SelexION® Technology is an effective differential ion mobility separation tool for improving data quality in the quantitation and characterization of challenging samples requiring advanced analytical selectivity.