Obtain fast, quantitative data for purity and integrity analysis of therapeutic proteins.
Obtain fast, quantitative data for purity and integrity analysis of therapeutic proteins.
Rapid determination of protein purity with capillary electrophoresis sodium dodecyl sulfate
CE-SDS is widely used throughout therapeutic drug development for lot release, stability testing, formulation-buffer screening, process development, cell line development and product characterization.
Maximize the way you work with validated kits and methods designed to optimize resolution and throughput.
The SDS-MW analysis kit is designed for use on the PA 800 Plus system and used for the separation and sizing of protein-SDS complexes.
Estimate molecular weight of an unknown protein
Quantify the amount of protein
Determine the purity of a protein product.
This kit uses a replaceable gel matrix formulated to provide an effective protein sieving range of approximately 10kDa to 225kDa.
Includes reagent volumes for analysis of 100 samples and components allowing for protein sizing.
As the drug development pipeline evolves, so do throughput needs. This kit is for use on the BioPhase 8800 system, designed to meet throughput demands by enabling 8 samples to be run in parallel, significantly increasing throughput and eliminating analytical bottlenecks.
Flexible workflows tailored for high-throughput CE-SDS analysis, for the BioPhase 8800 system optimize time to answer while ensuring excellent intermediate precision, accuracy, and separation efficiency.
This kit is designed for use on the PA 800 Plus and is used to assess the purity and heterogeneity of IgG molecules in both a reduced and non-reduced state, and will detect impurities as low as 0.1%.
This kit provides reagent volumes for analysis of 100 samples.
Established technology from development throughout QC delivering high data quality with kit-based workflows.
Pre-assembled bare-fused silica capillary cartridge compatible with the RNA 9000 Purity & Integrity kit and the PA 800 Plus system
Purpose-built for the biopharmaceutical scientists seeking high-quality data, enabling multiple samples to be run in parallel.
Pre-assembled bare-fused silica 8-capillary cartridge compatible with the RNA 9000 Purity & Integrity kit and the BioPhase 8800 system.
Set the pace with confidence. Cell line monitoring and analysis solutions verify the identity, purity and stability of lead candidates with high throughput strategies that are ready for automation.
Be clear on what you have and how much. Understand ADC drug loading profiles regardless of the inherent heterogeneity and high molecular weight of these molecules.
Optimize your processes with solutions that overcome the analytical challenges of viral vector-based drugs. Take control of full and empty ratios and protein and genome profiles. Break down the boundaries of protein and post-translational modification (PTM) characterization with dedicated high-resolution workflows offering unprecedented depth.
Take chimeric antigen receptor (CAR) T-cell therapy and other cell therapy programs to the next level with tailored analytical solutions that provide actionable answers. Evaluate lentiviral vectors and lipid nanoparticles for gene editing and understand proteome changes with a collaborative team of experts.
Technical note
Intermediate precision study of capillary electrophoresissodium dodecyl sulfate (CE-SDS) assay on the BioPhase 8800 system
Technical note
Lightning capillary electrophoresis sodium dodecyl sulfate (CE-SDS) workflow for high-throughput analysis of biotherapeutics
Technical note
Unleashing the Power of Speed: Accelerating time to answer with CE-SDS and Laser-Induced Fluorescence detection in under 12 Minutes
Technical note
Multi-capillary gel electrophoresis to increase throughput for the purity analysis of biotherapeutic proteins
Technical note
Efficient transfer of the high‐speed CE‐SDS method from the PA 800 Plus system to the BioPhase 8800 system
Technical note
Automation of CE-SDS sample preparation for PA 800 series IgG purity/ heterogeneity assays
Technical note
Assay of IgG purity and heterogeneity using high-resolution sodium dodecyl sulfate capillary gel eletrophoresis