Quantitative bioanalysis

Unlock reliable and sensitive quantitative biological data with LC-MS solutions that work as hard as you do.

Overview

Make your bioanalysis effortless when quantifying small and large molecule therapeutic candidates, including cyclic peptides and glucagon-like peptide-1 (GLP-1).

At SCIEX, we are committed to developing LC-MS/MS solutions that streamline and accelerate your bioanalytical assays. Our state-of-the-art hardware and software facilitate rapid quantitation, even for low-abundant ions, ensuring the efficient progression of drug candidates through the pipeline.

Featuring cyclic peptides

Workflow

Gather the precise and reliable data you need to confidently navigate the complexities of cyclic peptide analysis, to advance your next therapeutic.

  • Sub ng/mL level of quantitation even in complex biological matrices.
  • Low plasma consumption.
  • Compliance-ready software to reduce the burden in a regulated environment.

Cyclic peptides

ExionLC AE system

Reproducibility, reliability and carryover performance to match your quantitative workflows. Dependability you can count on, from injection to injection and batch after batch.

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ZenoTOF 7600 system

A high-resolution mass spectrometry solution that combines powerful MS/MS sensitivity, fragmentation technology and a step-change in data independent acquisition.

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SCIEX OS software

Unleash the analytical power of the next-generation software platform for data acquisition and processing.

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Service

Keep your instruments performing at their peak, with multiple options for response time, repair coverage and maintenance.

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Featuring GLP-1

Workflow

Breeze through your GLP-1 based analysis in biological matrices with highly sensitive and specific LC-MS systems.

Achieve accurate quantitation even at low concentrations, providing valuable insights into pharmacokinetics and pharmacodynamics.

  • Accelerate quantitative GLP-1 assays with high-sensitivity LC-MS/MS solutions that deliver reliable data.
  • Confidently detect low-level species with robust, high-sensitivity LC-MS/MS analyses.
  • Be audit-ready with streamlined, compliance-ready software.
ExionLC AE system

Reproducibility, reliability and carryover performance to match your quantitative workflows. Dependability you can count on, from injection to injection and batch after batch.

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SCIEX 7500+ Triple Quad system – QTRAP ready

Setting a new standard for instrument resilience and robustness, the SCIEX 7500+ system gives you the confidence to face evolving analytical challenges. Tackle tight timelines with exceptional sensitivity and with the power to control your instrument downtime.

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SCIEX OS software

Unleash the analytical power of the next-generation software platform for data acquisition and processing.

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Service

Keep your instruments performing at their peak, with multiple options for response time, repair coverage and maintenance.

Learn more

Small molecule quantitative bioanalysis

Workflow

Gain deep insights into your drug candidate's pharmacokinetics, pharmacodynamics, and overall efficacy with powerful LC-MS solutions from SCIEX.

Your scientists will be able to obtain accurate and reproducible results, advancing drug candidates and ensuring the safety and effectiveness of new therapies.

  • Ideal quantitative performance, with %CV <10% in matrices.
  • The support you need, from the experts you trust.
  • Compliance-ready software to reduce the burden in a regulated environment.

Routine small molecule quantitation

ExionLC AE system

Reproducibility, reliability and carryover performance to match your quantitative workflows. Dependability you can count on, from injection to injection and batch after batch.

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SCIEX Triple Quad 6500+ system

Delivering the perfect balance of speed, performance, and sensitivity for your most challenges analytes.

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SCIEX OS software

Unleash the analytical power of the next-generation software platform for data acquisition and processing.

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Service

Keep your instruments performing at their peak, with multiple options for response time, repair coverage and maintenance.

Learn more

Absolute sensitivity for small molecule quantitation

ExionLC AE system

Reproducibility, reliability and carryover performance to match your quantitative workflows. Dependability you can count on, from injection to injection and batch after batch.

Learn more
SCIEX 7500+ Triple Quad system – QTRAP ready

Setting a new standard for instrument resilience and robustness, the SCIEX 7500+ system gives you the confidence to face evolving analytical challenges. Tackle tight timelines with exceptional sensitivity and with the power to control your instrument downtime.

Learn more
SCIEX OS software

Unleash the analytical power of the next-generation software platform for data acquisition and processing.

Learn more
Service

Keep your instruments performing at their peak, with multiple options for response time, repair coverage and maintenance.

Learn more

Large molecule quantitative bioanalysis

Workflow

Easily and confidently analyze large molecules such as proteins, peptides, and monoclonal antibodies to understand their pharmacokinetics, pharmacodynamics, and therapeutic efficacy, even in complex matrices.

Empower your scientists to quantify these compounds providing detailed insights into their behavior and interactions within the body.

  • An alternative technique to traditional ligand binding assays.
  • Linearity across a wide concentration range.
  • Data management and compliance-readiness (21 CFR Part 11) features using SCIEX OS software.

Routine large molecule quantitation

ExionLC AE system

Reproducibility, reliability and carryover performance to match your quantitative workflows. Dependability you can count on, from injection to injection and batch after batch.

Learn more
ZenoTOF 7600 system

A high-resolution mass spectrometry solution that combines powerful MS/MS sensitivity, fragmentation technology and a step-change in data independent acquisition.

Learn more
SCIEX OS software

Unleash the analytical power of the next-generation software platform for data acquisition and processing.

Learn more
Service

Keep your instruments performing at their peak, with multiple options for response time, repair coverage and maintenance.

Learn more

Absolute sensitivity for large molecule quantitation

ExionLC AE system

Reproducibility, reliability and carryover performance to match your quantitative workflows. Dependability you can count on, from injection to injection and batch after batch.

Learn more
SCIEX 7500+ Triple Quad system – QTRAP ready

Setting a new standard for instrument resilience and robustness, the SCIEX 7500+ system gives you the confidence to face evolving analytical challenges. Tackle tight timelines with exceptional sensitivity and with the power to control your instrument downtime.

Learn more
SCIEX OS software

Unleash the analytical power of the next-generation software platform for data acquisition and processing.

Learn more
Service

Keep your instruments performing at their peak, with multiple options for response time, repair coverage and maintenance.

Learn more

All resources

Associated applications

Biomarker quantitation

Explore the potential of trusted LC-MS/MS solutions designed to simplify and accelerate biomarker quantitation. Bring drug candidates through the development pipeline more efficiently and confidently with accurate results obtained using innovative hardware and software, lab-tested methods and expert support.

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ADME-Tox and DMPK

Advance the development of your next therapeutic drug with easy-to-operate, integrated analytical systems that can provide new insights into ADME-Tox and DMPK. Rapidly and comprehensively characterize drug candidates with robust and sensitive solutions for identification, monitoring and quantitation.

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Metabolite identification

Advance your drug discoveries with reliable metabolite data that save time and money. Our range of solutions supports routine monitoring and complex identification to give your team confidence during synthetic therapeutic development.

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Targeted protein degraders and PROTACs

Easily advance your targeted protein degraders and proteolysis targeting chimeras (PROTACs) with reliable and sensitive analytical data. Give your team the confidence to develop synthetic therapeutics with the support of the SCIEX technical team.

Learn more