Antibody-Drug Conjugate Structural Characterization – Part 1: Analysis of Conjugation Site DAR

In this webinar, we will show how CESI-MS can generate 100% sequence coverage of ADCs from a single 200 fmol injection. We will describe how we can identify the drug-loaded-peptides and other modification sites from the same data set and how MS/MS data helps to unambiguously characterize these drug-loaded-peptides. (37:45 min)