Database Assisted Capillary Electrophoresis for Analytical Glycomics

Facing the challenge of the immense structural diversity of carbohydrates, comprising positional and/or linkage isomers, CE is today a priceless tool for their analysis due to its hydrodynamic volume differences based separation principle. Sequential exoglycosidase digestion and analytical/preparative chromatography are providing valuable complementary or even orthogonal information, thus expanding the scope of CE. (Video 69:11 min)