Proteome-wide Profiling of Drug Dose-Response in Prostate Cancer Cell Lines by Microflow SWATH® Acquisition
Studying the mechanisms of drug resistance by performing proteome wide perturbation experiments after drug exposure would valuable, however is not done due to lack of fast robust methods for measuring global protein changes. Here microflow SWATH acquisition is used to determine drug-dose response curves on two prostate cancer cell lines. (18:43 min)min