For research use only. Not for use in diagnostic procedures.
Simplifying the processing of biotherapeutic data for characterization and comparability can dramatically improve productivity. BioPharmaView software accelerates characterization and comparability studies and simplifies reporting, so you can make better decisions, faster.
Gain a comprehensive view by analyzing intact protein or protease digested forms in reduced or non-reduced states from both LC-MS and CESI-MS workflows performed on the TripleTOF® or X500B QTOF accurate mass systems. Now with the ability to process data-independent SWATH® Acquisition analyses. BioPharmaView Software enables you to quickly identify differences from site-to-site and from lot-to-lot, even with large datasets. The software's automated calculation of key attributes like DAR, PTM ratio and disulfide bond location helps you rapidly turn your data into answers.
Built for Speed — Biologics and Biosimilar Analysis
BioPharmaView™ Software was designed with one thing in mind — accelerate biologics and biosimilar characterization and comparability analyses. Powered by revolutionary data processing for core characterization workflows, the software delivers exceptional investigative capabilities and data visualization in a high-throughput batch format.
Add speed and performance to your biotherapeutic analyses with powerful automated data processing tools. Assess intact mass and peptide mapping data quickly, and easily identify product differences from site-to-site and lot-to-lot, even with large data sets.
The software is designed from the ground up with both experts and non-experts in mind, so you can focus on delivering results quickly. With BioPharmaView Software, you easily generate your biologics characterization results faster as the software simplifies comparability assessments.
Spend more time understanding your data and less time processing samples. Crunch numbers easily with batch processing functions and automated ratio calculations for both post-translational modifications as well as drug-to-antibody analysis.
Fast and accurate data processing for intact mass analysis is essential for comparing biologic product characteristics. BioPharmaView Software makes it easy with one click batch processing, protein form matching and automated ratio calculations for post-translational modifications, including glycosylation. The multi-pane view in the main window allows you to see the processed and raw data from multiple samples side by side so that you can be confident about your comparability conclusions.
Intact analysis of antibody-drug conjugates (ADCs) can be challenging because of the size and complexity of the molecules. There’s no need to worry about your ADCs with automated drug-antibody ratio (DAR) calculation and visualization, as well as a simplified—yet highly accurate—view of protein deconvolution in BioPharmaView Software. Comparing ADC products is much easier when you can see drug load and DAR across multiple samples, so you’ll be clear on just what you’ve got—and how much.
Go from peptide mapping data to answers in four easy steps with the BioPharmaView Software. Get a quick look at protein sequence coverage from your peptide mapping data, as well a comprehensive list of identified peptides that are directly linked to high-resolution TOF-MS and annotated MS/MS data so you can quickly confirm each peptide.
Proprietary SWATH® Acquisition for peptide mapping provides comprehensive data collection and eliminates the need for IDA criteria set-up and traditional method development. With SWATH Acquisition, high-resolution MS/MS are acquired for all precursor ions, providing truly comprehensive and unbiased data collection. The unbiased approach enables acquisition of high-resolution, accurate mass MS/MS spectra of all low abundance peptides and post-translational modifications (PTMs) that could be missed by information dependent peptide map workflows. Furthermore, a standard, generic SWATH method can be used for almost every biotherapeutic peptide mapping analysis, further simplifying your workflow setup and helping you get answers faster.
Using SWATH Acquisition, BioPharmaView Software processing, you can detect low-level modifications and confirm them in high-resolution MS/MS spectra within a single run. The image above illustrates how SWATH and BioPharmaView Software works together on the X500B QTOF system.
Let the software quickly and accurately map disulfide bond locations to simplify your data analysis. The built-in algorithms in BioPharmaView Software make quick work of defining the bond locations and presenting the high-resolution, annotated MS/MS spectra including multiple charge state identification for disulfide bond localization and confirmation.