The Power of Precision
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Advance your research with front-end
instruments designed to help you realize the full power of your mass
spectrometer. SCIEX has the broadest portfolio of ESI-MS front-ends
can facilitate various flow rates, sample requirements and
sensitivities. No one else offers the entire range
flow, microflow, nanoflow LC-MS and even ultra-low flow
ExionLC 2.0 series
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Differential mobility spectrometry (DMS) and
ion mobility spectrometry are analytical techniques used to separate
ions based on their gas phase mobility. Multiple types of ion
devices exist, such as drift tubes, traveling wave, and high-field
asymmetric waveform devices. Learn how you can separate yourself
Differential Ion Mobility.
The latest ion sources from SCIEX enable
enhanced sensitivity and robustness with greater desolvation range
across all MS platforms, from Triple Quad to QTRAP and QTOF.
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vMethod applications are pre-configured and verified LC-MS/MS
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details for applicable MS/MS library databases for key applications.
and personal care products (PPCPs)
and protein bioanalysis
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at your fingertips, you can easily create methods and process
and non-targeted screening data on your complex samples, faster and
easier than ever before.
All in one
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iChemistry Solutions are the world's only reagents and
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kit for amino acid analysis of hydrolysates
kit for amino acid analysis of physiological fluids
protein digestion solution
Biologics analysis kit for
protein assay - human induction kit
CZE rapid charge variant analysis kit
glycan analysis and labeling for the PA 800 plus
standards kit for pesticide analysis
auEChERS extraction and dispersive kit
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From substantiating new discoveries through
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in the clinic, thousands of scientists worldwide depend upon mass
innovation from SCIEX to advance their work in the fields of
research, omics and diagnostics.
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quality of your food testing data is vital to your business. SCIEX
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data that you can genuinely count upon. With a portfolio of
applications, your lab can quickly and easily react to diverse
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results in an industry that is never constant? By accurately
even the smallest compound angles you can deliver evidence that
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data across a multitude of compounds and biomarkers, from the known
the new and novel.
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Transform the capacity and capability of your biologics pipeline
complete end-to-end solutions that make your lab more productive,
more successful. With a longstanding track record in pharma
development and manufacturing, our unparalleled application
with best-in-class hardware, software and support all integrate to
revolutionize your lab.
Native Mode Analysis
Nucleic Acid and Plasmid Analysis
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The SCIEX Now Learning Hub offers the most diverse and flexible learning options available, with best-inclass content that helps you to get the most out of your instrument and take your lab to the next level. Available personalized learning paths based on the latest memory science ensure better knowledge retention, and automated onboarding and enrollment means you’ll get up and running faster.
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Whether you are involved in biopharma discovery, early development or late development, you need fast and dependable peptide mapping analysis techniques that you can count on.
In early development candidate selection, determining the appropriate critical quality attributes (CQAs) is paramount and depends on extremely complex data processing and analysis. In late development, throughput is your top priority so you can quickly process and analyze high sample volumes. Although the requirements of peptide mapping analyses change during the development pipeline, the need to store, access and share large data sets is consistent throughout.
With SCIEX mass spec solutions, you can now benefit from 100% sequence coverage in a single injection and see low-level post-translation modifications (PTMs) faster than ever before.
SCIEX combines cutting-edge mass spectrometry technology into an integrated solution designed specifically to address the challenges of peptide mapping at all stages of the therapeutic development pipeline.
New depths of peptide mapping analysis with the ZenoTOF 7600 system
Electron activated dissociation (EAD) with fast data-dependent acquisition (DDA) enables alternative fragmentation for routine, in-depth analysis of next-generation protein therapeutics and standard monoclonal antibodies (mAbs).
Comprehensive sequence analysis with CESI-MS
Experience the orthogonal separation technique of CESI-MS, which provides 100% sequence coverage with a single injection from a single protease digestion.
Peptide analysis becomes routine with the X500B QTOF system
Simplify and accelerate peptide mapping workflows with the powerful and intuitive X500B QTOF system, which eliminates complex method development by using a generic data-independent SWATH acquisition method for the analysis of all detectable peptides in a sample.
Answers at the speed of light
Eliminate time-consuming manual data analysis, interpretation and reporting with revolutionary BioPharmaView software. Process large batches, annotate the peptide sequence and report detailed quantification information—it's automated and accurate.
CESI-MS has exceptional separation efficiency for peptides (especially very short, very long or highly charged peptides) and glycopeptide mapping of mAbs. It can differentiate between Asp and isoAsp deamidation and other PTMs, with the exceptional ability to provide 100% coverage from a single enzyme digestion in a single analysis.
The powerful X500B QTOF system combined with the intuitive SCIEX OS software point-and-click icon-based interface has revolutionized routine peptide analysis. Dramatically reducing the complexity of setting up LC-MS methods and batches, the system makes standardized peptide mapping analyses accessible to scientists of any skill level, without the involvement of mass spec experts. The use of SWATH acquisition, an unbiased data-independent acquisition strategy, requires no up-front method development and can provide comprehensive sample coverage for all detectable peptides in a single injection.
Now you can get faster answers to your peptide mapping questions with the powerful data processing capabilities of BioPharmaView software. Combined with the accurate mass data from the X500B QTOF or TripleTOF systems, it is a rapid and intuitive package for analyzing your peptide mapping data.
For biopharma development labs that need to do standardized peptide mapping analyses, the X500B QTOF system offers an easy-to-use platform that is accessible to all user levels.
Discover the power of Zeno trap with EAD fragmentation technology in this accurate mass system.
The ExionLC AD system delivers high accuracy, reliability and repeatability across thousands of injections, with maximum uptime.
Experience high-speed accurate mass analysis with a compact and streamlined QTOF system and the renowned Turbo V ion source.
Intuitive point-and-click acquisition software makes it easier than ever to set up and run your methods.
Reach decisions on the most important critical quality attributes for biopharmaceuticals faster and more confidently.
Get up and running quickly with access to our online training programs designed specifically for biotherapeutic characterization.
Comprehensive peptide mapping of biopharmaceuticals utilizing electron activated dissociation (EAD)
Differentiation of aspartic and isoaspartic acid using electron activated dissociation (EAD)
Differentiation of leucine and isoleucine using electron activated dissociation (EAD)
A new electron activated dissociation (EAD) approach for comprehensive glycopeptide analysis of therapeutic proteins
Confirmation of disulfide linkages in adalimumab using electron activated dissociation (EAD)
Evaluation of biotherapeutic sequence coverage using electron activated dissociation (EAD)
Simple solutions to complex workflows: innovation for biotherapeutic peptide mapping
Enabling the use of mass spectrometry throughout biopharmaceutical development
For labs that need to perform in-depth biotherapeutic characterization, the increased sensitivity provided by the CESI 8000 Plus for CE separation and the enhanced dynamic range of the TripleTOF 6600 system can help you get the advanced answers you need.
Enable in-depth characterization of digested biologic products, especially short peptides, long hydrophobic peptides, drug-linked peptides, glycopeptides and deamidated peptides.
Experience maximal sensitivity and a broad linear quantification range for large molecules with a system that is ideal for in-depth characterization and detection of low-level peptide species.
Rapid characterization of biologics using CESI and TripleTOF systems
Multilevel characterization of biotherapeutics using CESI-MS: from intact protein to peptide mapping.
Intact proteoform characterization using CESI-MS
CESI-MS for multilevel characterization of protein therapeutics
Fast, efficient, disulfide bond mapping using BioPharmaView software
Automated high throughput trypsin digests for highly reproducible peptide map analysis
BioPharmaView software 2.0: innovation for biotherapeutic characterization and comparability
The destination for all your support needs