The SCIEX clinical diagnostic portfolio is For In Vitro Diagnostic Use. Rx Only. Product(s) not available in all countries. For information on availability, please contact your local sales representative or refer to https://sciex.com/diagnostics. All other products are For Research Use Only. Not for use in Diagnostic Procedures.
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Built specifically for biologics characterization, the X500B QTOF System will help you boost your analytical capacity, simplify workflows and accelerate throughput in a matter of days. This high resolution Quadrupole Time-of-Flight (QTOF) system combines robust and reliable instrumentation with powerful and intuitive software to get you to characterization answers faster and easier, in a true benchtop platform. And with tools to enable a complete Multiple Attribute Methodology (MAM) Workflow, to allow you to define, track and quantify product quality attributes as well as specified contaminants, or find new unspecified impurities in a single software solution.
The powerful data processing and high impact visualization in BioPharmaView™ Software empowers analytical scientists, enabling them to process data into high quality answers on their biotherapeutics.
Rapidly turn your biologics characterization data into answers with the BioPharmaView™ Software.
Explore the new features of the BioPharmaView Software, including disulfide bond localization and automated DAR calculations.
Develop and implement a multiple attribute methodology (MAM) workflow with the new capabilities of BioPharmaView™ Software 3.0 to accelerate your biologic development.
Designed especially for robustness and reliability, the X500B QTOF system gives you reproducible biologics results with maximum system uptime. From the front end all the way through the TOF path, see how the X500B System is built for reliability.
The true benchtop stature of the X500B QTOF system occupies less of your valuable lab space than any other high resolution mass spectrometry system on the market today.
See what gives this benchtop system the performance edge.
A compact true benchtop system, with an ambidextrous dress panel to easily fit in your available space
Renowned, SCIEX Turbo V™ Ionization Source for maximum robustness
The all-new SCIEX OS user interface is incredibly easy to learn and maintain
BioPharmaView™ Software delivers data visualization and automated calculations for intact, subunit, and peptide level analyses
Automated on-board calibration and dual-spray source gives worry free acquisition
Easy Qjet™ Ion Guide access for straightforward maintenance
Heated TOF path eliminates environmental temperature impact
The X500B QTOF System was designed from the ground up to accelerate every day biologics characterization workflows.
The X500B QTOF is a Complete Solution for Biologics Characterization. The X500B provides a complete solution, designed to elevate your biologics characterization to a whole new level of productivity.
A perfect match for the X500B QTOF system, delivering reliability and repeatability.
Standard Biologics Characterization Executive Brief
Intact Mass Analysis Solution Guide
Peptide Mapping Solution Guide
Biotherapeutic Comparability Solution Guide
X500B Method Flyers
Intact Analysis of Antibody Drug Conjugates
Glycosylated and Deglycosylated Subunit Analysis of Antibody Drug Conjugates
Comparative Peptide Mapping Between Two Manufacturers of Trastuzumab Using the X500B QTOF System
Routine Workflow for Comparability Assessment of Protein Biopharmaceuticals
Comparative Multi-Supplier Lot Analysis of Trastuzumab Using Subunit Analysis on the X500B QTOF System
SCIEX OS Introduction Videos
MAM Workflow Executive Brief
MAM Overview Brochure
BPV 3.0 Software Bulletin
1. Novel N-optic TOF design gives optimal mass accuracy and resolution, even for large biotherapeutics such as mAbs and antibody drug conjugates
2. Renowned Turbo V™ source provides efficient ion production while limiting contamination for maximized robustness and uptime
3. Purpose built for biologics characterization and engineered with ease-of-use and simplicity in mind to accelerate and streamline biotherapeutic analysis
4. Perform intact mass, subunit analysis, and peptide mapping characterization on this single, true benchtop system
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