Collaboration on Novel iCIEF-MS Platform speeds up critical decisions and streamlines approaches in biopharma environment
April 08, 2020
Framingham, MA and Newark, CA — SCIEX, a global leader in life science analytical technologies, and Intabio, a developer of innovative instrumentation systems for biotherapeutic precision analysis and quality assessment, announced a collaboration to couple Intabio's Blaze™ system with SCIEX high resolution accurate mass (HRAM) systems. This collaboration is geared to accelerate and transform biotherapeutic development and biomanufacturing.
The integration between Blaze and SCIEX HRAM systems provides imaged capillary isoelectric focusing with mass spectrometry (iCIEF-MS) in order to simultaneously characterize and identify intact protein charge variants. The successful integration of iCIEF-MS workflows will streamline current laborious and time-consuming approaches in the biopharma environment to identify, monitor and characterize critical quality attributes in intact protein samples for the development and manufacture of next-gen therapeutics..
“By coupling iCIEF separations directly to leading high resolution MS systems, the Blaze system eliminates a serious laboratory bottleneck for drug developers,” said Lena Wu, Ph.D., Intabio CEO and co-founder. “Blaze integration with SCIEX flagship MS platforms will enable biopharma to accelerate critical decisions and ultimately reduce development timelines.”
The commercial release of the Blaze™ system is scheduled for Q4 of 2020 and the integrated iCIEF-MS workflow will be available on SCIEX TripleTOF® 6600+ Systems.
“This work demonstrates our continued commitment to collaborate with key innovators to develop practical solutions for our biopharmaceutical customers,” said Mani Krishnan, Vice President of Global Biopharma and Capillary Electrophoresis at SCIEX. “Providing analytical workflows around iCIEF-MS will assist in solving some of the key challenges faced by the industry.”
About SCIEX
SCIEX helps to improve the world we live in by enabling scientists and laboratory analysts to find answers to the complex analytical challenges they face. The company's global leadership and world-class service and support in the capillary electrophoresis and liquid chromatography-mass spectrometry industry have made it a trusted partner to thousands of the scientists and lab analysts worldwide who are focused on basic research, drug discovery and development, food and environmental testing, forensics and clinical research.
With over 40 years of proven innovation, SCIEX excels by listening to and understanding the ever-evolving needs of its customers to develop reliable, sensitive and intuitive solutions that continue to redefine what is achievable in routine and complex analysis. For more information, please visit sciex.com
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About Intabio
Intabio, Inc. is a Silicon Valley-based company developing analytical solutions to transform biotherapeutic development and manufacturing with products that provide early product quality characterization and profound efficiency gains across all stages of biopharmaceutical development and manufacturing. Intabio's first product, the Blaze system, is a microchip-based instrument system that will provide rapid detection and identification of subtle protein modifications - modifications that can undermine the stability and efficacy of biotherapeutic drugs such as monoclonal antibodies and recombinant proteins.
For more information, visit www.intabio.com.
Contact Information
Lulu VanZandt
Program Manager, Brand, Public Relations and Social Media, SCIEX
lulu.vanzandt@sciex.com
+1 (508) 383-7163
M: +1 (508) 782-9484
Wally Ausserer, Ph.D.
Strategic Advisor, Intabio
wally.ausserer@intabio.com
M: +1 (916) 335-8002
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