Don't compromise - obtain high-quality data, at speed.
Redefine your high-throughput analysis
Combining high data quality and high-throughput analysis
When the quantity of samples is your challenge, breakthrough with the Echo® MS+ system. The Echo® MS+ system gives you high-quality data, analytical flexibility and high sample throughput so you can make informed decisions, today. With sampling rates of up to 1 sample per second, results can be generated on the same day. The Echo® MS+ system is a complete solution that removes bottlenecks in high-throughput analytical workflows, from sample preparation to data reporting.
Choose the right Echo® MS+ system for your laboratory
The Echo® MS+ system is available in two configurations:
offering you the flexibility to meet the needs of your laboratory.
How AEMS takes your analysis to the new level
The Echo® MS+ system uses Acoustic Ejection Mass Spectrometry (AEMS). Samples are placed into compatible microtiter plates that are held in the Echo® MS+ system autosampler. Here, sound energy is applied to the bottom of each well individually. The sound energy causes reproducible droplets to be ejected from the well for capture in a carrier solvent of the OPI for dilution and transfer to the mass spectrometer source. From this point, the diluted sample is ionized using conventional electrospray ionization, making it ready for detection.
Redefining high-throughput mass spectrometry
Deliver high-quality data, minimize sample handling and eliminate carry over with contactless acoustic ejection sampling. Retain the precise, information-rich data needed to make informed decisions about your samples.
Achieve unparalleled standards of quantitation and qualification, at speed. The Echo® MS+ system provides consistency and precision in challenging matrices. Its high specificity enables confidence in results, and both decreases the need for re-runs and saves on reagent costs when compared to other technologies.
Conquer throughput barriers and decrease overall turnaround time with sampling speeds of up to 1 sample per second. Screen substrate and product simultaneously and reduce the number of analytical steps in your process.
The Echo® MS+ system in your lab
Redefining high-throughput quan/qual workflows
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The Echo® MS+ system is compatible with either the SCIEX Triple Quad 6500+ system or the ZenoTOF 7600 system for trusted mass spectrometry performance.
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Sample ejection allows for rapid sampling and reduced carryover.
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The system is compatible with robotic automation systems—automating steps such as sample preparation, plate preparation, plate loading/unloading, and plate submission for analysis.
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The port wash allows for cleaning the electrode assembly between sample plates, increasing the number of ejections that generate high quality data before you need to manually replace consumables.
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The new features of SCIEX OS software allow:
- Enhanced solvent and additive options for analytical flexibility
- Data acquisition modes to enable robust quantitative and qualitative capability
- The ability to analyze samples directly from a DMSO matrix
Echo® MS+ system walkthrough
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Method setup is both simple and fast. With data acquisition taking as little as 1 sample per second, you can quickly test many options for ideal settings.
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The MS method is similar to standard MS systems, with parameters such as mass range or MRM transition needing to be defined. SCIEX OS software users will be familiar with this step.
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Acquire and process your data in SCIEX OS software, simplifying your workflows and empowering swift, well-informed decision-making.
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Featured resources
Selecting the right analytical technology to support drug discovery is a key decision. This infographic compares different analytical technologies in this space.
Discover an efficient method development approach for the analysis of small molecules and intact proteins by mass spectrometry, in biologically relevant buffers.
Learn about how the Echo® MS+ system can be used to screen 9 sample concentrations in 16 different buffers in approximately 11 minutes.
Read about how the Echo® MS+ system can rapidly quantify both arginine and citrulline in a single analysis with minimal sample preparation.
Learn more about system settings to optimize method robustness for optimum long-term performance.
Learn how to accelerate your drug discovery with innovative mass spectrometry solution.
Related topics
A high-resolution mass spectrometry solution that combines powerful MS/MS sensitivity, fragmentation technology and a step-change in data independent acquisition.
Delivering a balance of speed, performance, and sensitivity for your most challenging analytes.
Screen thousands of candidates for desirable drug properties and process data with confidence, faster. Get the information you need to make go/no-go decisions quickly in the drug discovery phase of your work.