Screen thousands of candidates for desirable drug properties and process data with confidence faster than ever before. Get the information you need to make go/no-go decisions as quickly as possible in the drug discovery phase of your work.
High-throughput mass spectrometry
Don't compromise - obtain high-quality, at speed
The Echo® MS+ system uses acoustic ejection mass spectrometry to deliver high-quality mass spectrometric detection at speed. Benefiting from:
- Sampling rate of up to 1 sample/second
- Minimize sample preparation
- Remove the potential for carryover with contactless sampling
- Remove the need for labelling reagents
Overview
Unlock fast, reliable data collection for high-throughput drug discovery, with minimal complexity. Our label-free solutions minimize sample handling, helping reduce sample preparation and maintain the highest data quality. With expert-level support at every step, transitioning to advanced mass spectrometry has never been smoother. Combine speed and reproducibility with integrated MS solutions designed for efficiency. From target discovery to lead optimization, get the reliable insights you need to move forward with confidence. And with intuitive, easy-to-learn tools backed by a trusted support team, that’s always on your side, you can focus on breakthroughs instead of troubleshooting.
High-throughput screening for small and large molecules
Workflow
Is the next life-changing drug one of the thousands waiting to be analyzed in your lab? Reduce the risk of missing it with high-quality data using the Echo® MS+ system.
Gather high-quality data while reducing reagent and sample costs with high sample throughput for critical go/no-go decisions during drug discovery. The Echo® MS+ system enables you to run thousands of samples and report results on the same day.
- Measure molecular masses for protein-ligand binding or intact protein species with AEMS technology for reliable, reproducible, and rapid results with low %CV.
- Identify and confirm the presence of target compounds in libraries with AEMS technology for accurate and reproducible results.
- Simplify analytical workflows with an all-in-one software solution.
- Service support goes beyond troubleshooting; SCIEX is your dedicated partner, ensuring reliable performance and expert guidance when you need it most.
High-throughput screening for small and large molecules
Suited for:
- High throughput screening for small molecules
- Biomolecule deconvolution
- High throughput experimentation
- Compound quality assessment
Echo® MS+ system with ZenoTOF 7600 system
Achieve the balance of unyielding data quality, speed, and cost for high-throughput screening workflows.
Learn more
SCIEX OS software
Unleash the analytical power of the next-generation software platform for data acquisition and processing.
Learn more
Service
Keep your instruments performing at their peak, with multiple options for response time, repair coverage and maintenance.
Learn more
High-throughput screening for biochemical assays and the highest levels of sensitivity
Suited for:
- HTS biochemical assays
- When a higher level of quantitative sensitivity and linear dynamic range is required
- Simplicity of general system operation
Echo® MS+ system with Triple Quad 6500+ system
Achieve the balance of unyielding data quality, speed, and cost for high-throughput screening workflows.
Learn more
SCIEX OS software
Unleash the analytical power of the next-generation software platform for data acquisition and processing.
Learn more
Service
Keep your instruments performing at their peak, with multiple options for response time, repair coverage and maintenance.
Learn more
Featured resources
-
Technical note
Optimal buffer concentration and compatibility for high-throughput intact protein analysis
Get to know about a rapid method for determining the optimal buffer conditions for the intact protein analysis of myoglobin - This can be applied to other analytes of interest.
-
Technical note
High-resolution, specific analysis of arginine and citrulline
Differentiate and quantify amino acids with minimal sample preparation using a high-throughput method.
-
Technical note
High-speed compound quality assessment
Rapidly identify 45 compounds using both polarities in less than 4 minutes.
-
Technical note
An automated, real-time measurement of the kinetic hydrolysis of a glucuronide
Quantify the analytes rapidly with Beckman Coulter® Life Sciences Biomek i7 automated liquid handler and the Echo® MS+ system with ZenoTOF 7600 system.
-
Technical note
Rapid and accurate quantitation of thyroglobulin biomarkers
Detect and quantify singly and doubly charged thyroglobulin peptides with the rapid Zeno MRMHR method.
-
Technical note
Rapid and accurate bioanalysis for drug screening
Learn about highly sensitive, highly specific, high-throughput quantitative solution for drug screening.
-
Technical note
Rapid insulin analysis before-and-after TCEP reduction
Achieve a high-throughput quantitative analysis of intact and reduced insulin. And read about how to get rapid analysis of insulin and its alpha and beta chains.
-
Flyer
Analytical solution for drug discovery assays
Selecting the right analytical technology to support drug discovery is a key decision. This infographic compares different analytical technologies in this space.
Target discovery and lead identification
Workflow
Enable your team to combine speed with exceptional reproducibility using integrated LC-MS/MS solutions. Confidently increase the efficiency and productivity of target discovery and lead optimization with reliable and accurate data. Our easy-to-learn and easy-to-use solutions are designed to ensure robust quality, and they have the added benefit of access to our extensive and expert support team.
- Simplify analytical workflows with an all-in-one software solution
- Easily obtain detailed data with intuitive data-independent acquisition (DIA)
- Increase sensitivity, speed and robustness using microflow chromatography
Target discovery and lead identification
Suited for:
- Realize superior quantitative performance with high sensitivity
ExionLC AE system
Reproducibility, reliability and carryover performance to match your quantitative workflows. Dependability you can count on, from injection to injection and batch after batch.
Learn more
SCIEX 7500+ Triple Quad system – QTRAP ready
Setting a new standard for instrument resilience and robustness, the SCIEX 7500+ system gives you the confidence to face evolving analytical challenges. Tackle tight timelines with exceptional sensitivity and with the power to control your instrument downtime.
Learn more
SCIEX OS software
Unleash the analytical power of the next-generation software platform for data acquisition and processing.
Learn more
Service
Keep your instruments performing at their peak, with multiple options for response time, repair coverage and maintenance.
Learn more
Target discovery and lead identification
Suited for:
- Quantitative and qualitative methods that offer analytical flexibility
ExionLC AE system
Reproducibility, reliability and carryover performance to match your quantitative workflows. Dependability you can count on, from injection to injection and batch after batch.
Learn more
SCIEX Triple Quad 6500+ system
Delivering the perfect balance of speed, performance, and sensitivity for your most challenges analytes.
Learn more
SCIEX OS software
Unleash the analytical power of the next-generation software platform for data acquisition and processing.
Learn more
Service
Keep your instruments performing at their peak, with multiple options for response time, repair coverage and maintenance.
Learn more
All resources
-
Technical note
Optimal buffer concentration and compatibility for high-throughput intact protein analysis
Get to know about a rapid method for determining the optimal buffer conditions for the intact protein analysis of myoglobin - This can be applied to other analytes of interest.
-
Technical note
High-resolution, specific analysis of arginine and citrulline
Differentiate and quantify amino acids with minimal sample preparation using a high-throughput method.
-
Technical note
High-speed compound quality assessment
Rapidly identify 45 compounds using both polarities in less than 4 minutes.
-
Technical note
An automated, real-time measurement of the kinetic hydrolysis of a glucuronide
Quantify the analytes rapidly with Beckman Coulter® Life Sciences Biomek i7 automated liquid handler and the Echo® MS+ system with ZenoTOF 7600 system.
-
Technical note
Rapid and accurate quantitation of thyroglobulin biomarkers
Detect and quantify singly and doubly charged thyroglobulin peptides with the rapid Zeno MRMHR method.
-
Technical note
Rapid and accurate bioanalysis for drug screening
Learn about highly sensitive, highly specific, high-throughput quantitative solution for drug screening.
-
Technical note
Rapid insulin analysis before-and-after TCEP reduction
Detect and quantify singly and doubly charged thyroglobulin peptides with the rapid Zeno MRMHR method.
-
Technical note
Robustness of the SCIEX 7500 system for small molecule analysis in tissue
Discover a new solution for analytical reproducibility via observational data from the determination of 2 standard pharmaceuticals in a rat liver tissue extract injected over 4,000 times.
-
Technical note
The SCIEX Triple Quad LC-MS/MS 6500 and the QTRAP 6500 LC-MS/MS systems for targeted quantitation
Read about a method that offers sensitivity and selectivity while maintaining robustness and throughput.
-
Flyer
Analytical solution for drug discovery assays
Selecting the right analytical technology to support drug discovery is a key decision. This infographic compares different analytical technologies in this space.
Associated applications
ADME-Tox and DMPK
Advance the development of your next therapeutic drug with easy-to-operate, integrated analytical systems that can provide new insights into ADME-Tox and DMPK. Rapidly and comprehensively characterize drug candidates with robust and sensitive solutions for identification, monitoring and quantitation.
Learn more
Metabolite identification
Advance your drug discoveries with reliable metabolite data that save time and money. Our range of solutions supports routine monitoring and complex identification.
Learn more