High-throughput mass spectrometry

Screen thousands of candidates for desirable drug properties and process data with confidence faster than ever before. Get the information you need to make go/no-go decisions as quickly as possible in the drug discovery phase of your work.

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Overview

Easily collect the data you need for quick decision-making in high-throughput drug discovery. Our label-free solutions help ensure optimum data reliability and high quality with minimal sample handling to save your team time and money. Enable a smooth and efficient transition to state-of-the-art mass spectrometry solutions with access to an expert-level support team.

Workflow

High-throughput screening for small and large molecules

When the quantity of samples is your challenge, breakthrough with the Echo MS+ system. The Echo MS+ system gives you high-quality data, analytical flexibility, and high sample throughput to make the right decisions today. With ejection rates of up to 1 sample/second, you can have results on the same day they are submitted to your lab. The Echo MS+ system is a complete solution that removes bottlenecks in high-throughput analytical workflows, from sample preparation to data reporting.

  • Quantify the target analytes with accuracy and speed
  • Easily report results with an automated end-to-end workflow
  • Measure molecular masses for large and small drug candidates
  • Minimize sample consumption with ejection volumes of 2.5 nL

High-throughput screening for small and large molecules

Solution

Workflow

Target discovery and lead identification

Enable your team to combine speed with exceptional reproducibility using integrated LC-MS/MS solutions. Confidently increase the efficiency and productivity of target discovery and lead optimization with reliable and accurate data. Our easy-to-learn and easy-to-use solutions are designed to ensure robust quality, and they have the added benefit of access to our extensive and expert support team.

  • Simplify analytical workflows with an all-in-one software solution
  • Easily obtain detailed data with intuitive data-independent acquisition (DIA)
  • Increase sensitivity, speed and robustness using microflow chromatography 

Target discovery and lead identification

Solution

Suited for:
  • Realize superior quantitative performance with high sensitivity
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Featured resources

Robustness of the SCIEX 7500 system for small molecule analysis in tissue

Discover a new solution for analytical reproducibility via observational data from the determination of 2 standard pharmaceuticals in a rat liver tissue extract injected over 4,000 times.

Target discovery and lead identification

Solution

Suited for:
  • Quantitative and qualitative methods that offer analytical flexibility
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Featured resources

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The SCIEX Triple Quad LC-MS/MS 6500 and the QTRAP 6500 LC-MS/MS systems for targeted quantitation

Read about a method that offers sensitivity and selectivity while maintaining robustness and throughput.

High sensitivity quantification of triptorelin deca peptide using the QTRAP 6500 system

Triptorelin, a ten amino acid synthetic peptide, is a gonadotropin-releasing hormone agonist (GnRH agonist). A high sensitivity, robust LC-MS/MS detection strategy on the QTRAP 6500 system is shown for monitoring triptorelin in rat and human plasma at low pg/mL levels during drug development.

All resources

Filter:
Robustness of the SCIEX 7500 system for small molecule analysis in tissue

Discover a new solution for analytical reproducibility via observational data from the determination of 2 standard pharmaceuticals in a rat liver tissue extract injected over 4,000 times.

The SCIEX Triple Quad LC-MS/MS 6500 and the QTRAP 6500 LC-MS/MS systems for targeted quantitation

Read about a method that offers sensitivity and selectivity while maintaining robustness and throughput.

High sensitivity quantification of triptorelin deca peptide using the QTRAP 6500 system

Triptorelin, a ten amino acid synthetic peptide, is a gonadotropin-releasing hormone agonist (GnRH agonist). A high sensitivity, robust LC-MS/MS detection strategy on the QTRAP 6500 system is shown for monitoring triptorelin in rat and human plasma at low pg/mL levels during drug development.

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