This collection of articles penned by some of the thought leaders in Bioanalysis addresses several challenges faced by Bioanalytical scientists in today's complicated world of large molecule Bioanalysis. From using nominal mass spectrometers to achieve ultimate sensitivity, to using accurate mass for quantitative and qualitative studies; from developing knowledge of using orthogonal selectivity tools for Bioanalysis to maximizing the use of software in data processing and analysis, this compendium offers you the ability to address your challenges in Bioanalysis.