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- iMethod Application Pesticide LC-MS/MS Library Version 1.1 for Cliquid Software
The Power of Precision
For research use only. Not for use in diagnostic procedures.
Get the all-inclusive pesticides MS/MS spectral library.
The SCIEX iMethod™ Pesticide LC-MS/MS Library Version 1.1 includes MS/MS spectra in positive and negative ion mode (where appropriate) at three collision energies for over 640 relevant pesticides. Collision energy spread (CES) as well as the corresponding MRM catalogue were provided, with up to six transitions per compound. Incorporate this library into your current methods or use with the iMethod™ Application for Pesticides Screening.
For system requirements and example results, read the flyer: iMethod™ Pesticide LC-MS/MS Library Version 1.0 for Cliquid® Software
The SCIEX iMethod™ Pesticide LC-MS/MS Library Version 1.1 contains information on 636 common pesticides and their metabolites that are required to be monitored in vegetables or other food products. The multiple reaction monitoring (MRM) catalogue contains up to three transitions per compound. Each compound in the library has individual spectra acquired using three distinct collision energies (20 eV, 35 eV, 50 eV), as well as a single spectra representing the sum of all three collision energies. If compounds ionize in both polarities, spectra for both are also included, bringing the total number of spectra per compound to eight.
Use stand-alone to create custom screening and/or quantification methods
The MRM catalogue can be used to build methods without the need to re-infuse standards and optimize MRM transitions for a given compound. Screening and quantitation methods can be created for use with an MRM-triggered enhanced product ion (EPI) workflow and a QTRAP® System; additionally, traditional quantitation can be completed using the response ratio for two or more transitions for compound confirmation. The latter approach can be performed on either an API Triple Quad™ System or a QTRAP® Series instrument. Users simply select the compounds of interest as well as the number of transitions to be monitored from the MRM catalogue. Once selected, the Cliquid® Software automatically creates the acquisition and processing methods.
Reduce development time
|Activity||Using an iMethod™ Application||Traditional Method Development|
|Complete Test Protocol Documentation||Included||Weeks–Months|
|Sample Prep Techniques||Included, with examples and references||Weeks–Months|
|Optimized MS/MS Acquisition Parameters||Included||Weeks–Months|
|LC Instrument Parameters with Retention Times||Included||Days–Weeks|
|Integration (Quantitation) Parameters||Included||Days|
|LC-MS/MS Library Spectra||May be included. Stand-alone libraries are also available.||Weeks–Months|
|Staff Training – Software||Simple Cliquid® Software interface, no additional training||Traditional MS Software and review procedures – Days|
|Method Validation||Weeks. Validation templates and support available||Weeks–Months|
|Complete Test Development and Deployment||Weeks||6–12 months|