Proteomics research

More meaningful answers to your proteomics research, more quickly

 

In the study of proteomics, until now, the sheer complexity of the proteome, with its variability and dynamic range, has dictated the need for specialized methods and compromises between discovery and quantification. Too often, lengthy research projects have resulted in long protein identification lists with ambiguous biological significance.

SCIEX delivers innovative tools that help proteomics researchers quickly find meaningful answers with confidence. With the launch of the ZenoTOF 7600 system, and its revolutionary Zeno trap and electron-activated dissociation (EAD), researchers can now routinely identify, quantify and characterize critical low-abundance proteins and their post-translational modifications, and unlock a new level of biological insight.

The power of the Zeno trap and EAD for data-dependent acquisition (DDA) approaches, as well as SWATH acquisition for data-independent acquisition (DIA) approaches, in high-quality quantitative MS/MS data, which leads to more insightful results in protein identification, labeled quantification and label-free quantification. The increased full-scan sensitivity and access to more diverse fragmentation mechanisms is also advantageous for the characterization of proteins, while the sensitivity of the SCIEX 7500 system for targeted MRM-based approaches means very low-abundance proteins can be readily quantified.

Discovery proteomics

Rapid, confident identification and quantification Generate and test hypotheses related to disease state or biological function. Key proteins are identified and quantified using labeled and label free strategies with DDA or DIA workflows.

Next-generation proteomics (NGP): Protein profiling and characterization

A deeper understanding of structure and function Discover both common and uncommon modifications with the precision to pinpoint the site of modification through EAD fragmentation.

Targeted proteomics

Confident quantification of larger sample cohorts Verification and validation of protein biomarkers require precise, targeted quantification across large numbers of samples to enable translation into clinical research.

SCIEX solutions for proteomics research

High-resolution accurate mass ZenoTOF 7600 system

Qualitative flexibility combined with quantitative power: A crucial step change in MS/MS technology, the ZenoTOF 7600 system unlocks new, precise perspectives on the proteome.​

OneOmics suite: Cloud-base mass spectrometry software

One cloud, countless opportunities. Drive big data to meaningful results with cloud computing. Streamline the analysis of your multi-omics data sets with the power of the OneOmics suite.

SCIEX OS mass spectrometer software for the modern laboratory

POWER UP: Streamline your targeted proteomics workflows with the usability, efficiency and integrity of SCIEX OS software.

Targeted proteomics with Triple Quad 7500 system - QTRAP Ready

GO BEYOND with the SCIEX 7500 system offers the high sensitivity and wide linear dynamic range you need for large-scale targeted peptide quantification.​

What our customers have to say

Dr. Birgit Schilling, PhD

Associate Professor, Director of the Mass Spectrometry Core, Buck Institute for Research on Aging, San Francisco, California, USA

Jennifer Van Eyk, PhD

Co-Director, Precision Health Cedars-Sinai, Los Angeles, California, USA

Tony Whetton

Director, Stoller Biomarker Discovery Centre, University of Manchester, UK

Talk Precision Medicine

Listen to thought leaders in the field share their ideas and knowledge about the power of precise science to advance human wellness and enhance our understanding of disease.

 

 

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