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OptiFlow Turbo V ion source
A revolution in low flow separations to maintain the perfect balance of robustness and sensitivity
- Based on the trusted Turbo V source design and with finger-tight fittings for tool-free setup
- New probes ensure consistent droplet formation for high-quality spray and optimized for multiple flow ranges:
- Micro: 1 - 10, 10 - 50, 50 - 200 µL/min
- Nano: 100 – 1000 nL/min
- Switch between nanoflow and microflow in minutes
CONTACT SUPPORT
Switching to high sensitivity low flow analyses couldn’t be easier
The robustness and simplicity you’ve come to expect from traditional analytical flow can now be experienced in your high sensitivity microflow and nanoflow analyses.
We have made this possible with standard size finger-tight fittings, and a new single-click source interface – allowing you to effortlessly connect your LC, column and mass spec. The OptiFlow source is equipped with intelligent probe recognition technology to preset system source settings and probe position, providing optimal spray and eliminating all manual adjustments.
Innovations that power your performance
Engineered with enhanced gas flow dynamics and IonDrive heaters for increased ion production and robustness, the OptiFlow source helps ensure consistency in results across multiple systems and multiple users. Extensive experiments were performed for nanoflow and microflow to find optimal probe positions, protrusions and typical gas and temperature settings.
Flexible flowrate range
Micro: 1 - 10, 10 - 50, 50 - 200 µL/min Nano: 100 – 1000 nL/min
Optimized without manual adjustments
Intelligent probe recognition technology presets system source settings to an optimal range for best spray conditions, and eliminate all manual adjustments on the source
No tool connections
Engineered with finger-tight standard size fittings to ensure a simple tool-free setup, every time
Integrated column heater
New column heater design with an expanded heating range up to 90˚C provides retention time consistency across runs
Fast switching
Change between nanoflow and microflow in minutes
Robust low flow analysis on high performance MS platforms
The OptiFlow source offers an easy-to-use, low flow ionization source to provide robust and high-performance ionization on select SCIEX Triple Quad and QTRAP instruments.
NanoLC 400
Most flexible low flow LC system, with microfluidic flow control for reproducibility across a wide flow rate range. Plug-and-play flow modules to switch between nanoflow (100 nL/min – 1 µL/min) and microflow (1-10, or 5-50 µL/min)
M5 MicroLC
Optimized MicroLC system for high-throughput workflows from 1-200 µL/min, and for use with limited sample volumes. The OptiFlow ion source is also compatible with M3 MicroLC and MicroLC 200 systems
6500+ series
Compatible with our fastest and most sensitive 6500+/6500 QTRAP and Triple Quad series instruments.
Triple Quad 5500+
Compatible with the high performance 5500+/5500 QTRAP and Triple Quad series MS instruments.
TripleTOF 6600+
Compatible with QTOF high resolution mass spec TripleTOF 6600+ instrument.
Phenomenex columns
- Variety of solid supports
- Trap and columns
- 300 µm & 500 µm i.d. in 5, 10, or 15 cm lengths
- Finger tight 1/16th fittings
- Range of chemistries optimized for specific applications
| Learning center | |
|---|---|
| Technical note: Single source solution for low flow chromatography - OptiFlow Turbo V source – Always working in the sweet spot of sensitivity and robustness | Download |
| Technical note: Improving sensitivity for Trastuzumab Emtansine quantification using trap-elute microLC-MS with large volume sample loading | Download |
| Technical note: Universal solution for monoclonal antibody quantification in biological fluids using trap-elute microLC-MS method | Download |
| Technical note: Sub-picogram level quantitation of desmopressin in small volumes of human plasma using a trap-elute microLC-MS system | Download |
| Video: OptiFlow interface on the TripleTOF 6600 system | Watch Now |
| Technical note: OptiFlow interface for TripleTOF | Download |
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