For research use only. Not for use in diagnostic procedures.
The TripleTOF 5600+ System is an innovation in LC-MS/MS performance that uniquely integrates comprehensive, qualitative exploration, rapid profiling, and high-resolution quantitation workflows on a single platform. It combines high-sensitivity detection, high resolution with the fast acquisition speeds, and stable mass accuracy over days of acquisition.
Expanding upon the capabilities of TripleTOF Technology, the 5600+ System provides broader applicability in pharmaceutical development and a new paradigm in proteomics research.
Featuring:
MS/MSALL with SWATH® Acquisition – enabling comprehensive MS/MS quantitation in proteomics
Tools for 21 CFR 11 Compliance – in Analyst® TF 1.6 and MultiQuant™ Software, bringing the power of accurate mass to regulated bioanalysis
Optional SelexION™ Technology – for an additional dimension of separation
High resolution at unparalleled speed with 10 msec accumulation time
EasyMass™ Accuracy – without constant recalibration, over 50 hours of continuous LC-MS operation provides stable mass accuracy.
SmartSpeed™ 100Hz Acquisition – delivering high resolution for high-speed chromatography with up to 100 spectra in a second – even in Information-Dependent Acquisition (IDA) mode
Sensitive, high-resolution system – low limits of quantitation (LOQ) for a high-resolution system and equivalent to high-performance triple quadrupoles
The TripleTOF 5600+ System is the next generation in quadrupole TOF technology. Combining the best-in-class front end of the Triple Quad 5500 System with the Accelerator TOF Analyzer, this instrument adds high resolution at the speed and sensitivity needed to give %CVs and limits of quantitation (LOQ) equivalent to those of high-end triple quadrupoles.
Now for the first time, pharmaceutical, academic, and analytical testing scientists can integrate comprehensive, qualitative exploration, rapid profiling, and high-resolution quantitation of low-abundance analytes in very complex matrices – all on a single platform.
Feature
Benefit
MS/MSALL with SWATH® Acquisition
Quantitative MS/MS data that rivals triple quadrupole sensitivity and precision for every component in complex samples. And... a complete digital archive of all precursor and product ions in a sample, for unlimited retrospective interrogation without the need to re-acquire data.
21 CFR 11 Compliance Module
Software tools that support digital record-keeping and electronic signatures, enabling the use of TripleTOF® Technology in a regulated environment.
Highest sensitivity with QJet Ion Guide and Accelerator TOF Analyzer
Low-abundance analytes easily discovered, identified, and quantified
SmartSpeed 100Hz Acquisition
The fastest, high-resolution system that generates more high-quality information from every sample, even when using fast chromatography
EasyMass Accuracy
Achieves high mass-accuracy without continuous recalibration, making it the easiest-to-use system for routine accurate mass.
One-touch productivity software
Increases productivity by facilitating powerful workflows to create information out of data
High resolution at up to 100 spectra per second
Definitive identification at high speed even when using fast chromatography
Magnetic levitation (MagLev) turbo pumps
New level of reliability for reduced cost of ownership and virtually silent running for a better lab environment.
Explore Workflow
Explore complex samples in greater depth: Select up to 50 precursors per second – and generate high resolution and high mass-accuracy MS/MS data using powerful IDA (Information-Dependent Acquisition) algorithms and high-resolution, accurate-mass MS and MS/MS.
Profile Workflow
Profile samples for quant and qual in a single run: Quantify virtually every compound in the sample with high-resolution MS quantification and fast chromatography; confirm compound identity with high-resolution, accurate-mass MS/MS; and then mine the data for the information you need.
Quantify Workflow
Quantify analytes with high-resolution MRM transitions for highest specificity and confidence: Obtain high resolution at high and low masses in the same spectrum for high-resolution, MRM-like quantification. The LOQ's and dynamic range are equivalent to high-performance triple quadrupoles. Cycle times are as low as 10 msec and generate superior peak definition, even with fast LC separations. Quantification requires little optimization, and you can choose multiple fragments per precursor from the acquired full-scan MS/MS data.
최적화된 이온 생성, 초점 조정, 반사 및 검출 기능을 갖춘 TripleTOF 5600+ 시스템을 통해 복잡한 시료를 더 심층적으로 분석할 수 있습니다.
IonDrive Turbo V Source
전설적인 Turbo V 소스의 새로운 설계로, 강화된 기체 유량 동적 특성과 최적화된 히터 구성을 통해 이온 생성이 증가하여 고속 유량에서 안정성, 재현성 및 내구성이 향상됩니다.
QJet® Ion Guide
QJet Ion 가이드의 내구성이 우수한 설계로, 포획 반경이 넓어져 이온이 소스에서 사중극자 광학 장치로 효율적으로 전달됩니다.
고주파 LINAC® 충돌 셀
구동 고주파 충돌 셀은 이온이 TOF에 유입되기 전에 이온을 포커싱하여 보다 우수한 이온 전달, 높은 듀티 사이클 및 향상된 분해능을 제공합니다.
Accelerator TOF™ Analyzer
TOF(Time-Of-Flight) 분석기는 2단계 미러와 15 kV 가속을 사용하여 분해능과 효율성을 향상시킵니다. 정량 분석과 같은 Triple Quadrupole에 필요한 속도와 감도뿐만 아니라 정성 분석 응용 분야를 위한 고분해능과 질량 정확도를 얻을 수 있습니다.
검출 시스템
TDC 프로세싱 기술을 활용한 4채널 MCP 검출기는 고이온 전류에서 내구성과 수명을 향상시키는 동시에 105 이상의 선형 다이내믹 레인지를 제공합니다.
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