Clarion Congress Hotel Prague, Prague, Czech Republic
November 5 – November 8, 2019
Join the conversation with our food experts and learn about the latest developments in mass spectrometry:
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Zbynek Dzuman Ph.D. University of Chemistry and Technology Dpt. of Food Analysis and Nutrition
Challenges and implementation of LC-MS method for multiple plant alkaloids analysis
Various groups of toxic plant alkaloids may enter human food chain. For control of the substances, reliable methods are needed. In this study, effective method for the detection of 56 pyrrolizidine, tropane and quinolizidine alkaloids utilizing ultra-high performance liquid chromatography and tandem mass spectrometry (QTRAP 6500+ System, SCIEX) has been developed.
Dr. Michael Sulyok, Institute of Bioanalytics and Agro-Metabolomics Department of Agrobiotechnology (IFA-Tulln) University of Natural Resources and Life Sciences, Vienna
Validation of LC-MS/MS based methods for the simultaneous quantification of several hundreds of analytes: Do we need new guidelines?
In the recent years, LC-MS based methods covering hundreds of analytes have been successfully developed in the field of mycotoxins, veterinary drugs and pesticides. However, the analytical burden involved in validation of such methods is huge, even if a "user-friendly" guideline like SANTE 11813/2017 is used. Based on the results we obtained on the validation of 550 mycotoxins and other secondary metabolites, this presentation aims to discuss the usefulness of current guidelines for multi-target analysis. In particular, we think that both absolute and relative matrix effects seem to be insufficiently addressed, whereas investigations close to the levels of LOD/LOQ (thus requiring manual checks / interventions as considers peak integration) may be significantly reduced.
How to register for SCIEX Workshop:
If you are registered for RAFA
If you are not registered for RAFA yet