Learn about new applications to advance your forensic workflows! Meet us at booth #504 to check out the latest LC-MS/MS based tools.
Sharpen your scientific skills with our Lunch & Learns. We will be joining forces with Phenomenex to show you the latest techniques in forensic science. Save your spot now by signing up.
Speaker:
Prof. Alberto Salomone, University of Turin, Italy
Hair analysis is an effective tool when used properly and can provide useful information in forensic toxicology. In this presentation, several examples will be discussed. The first and foremost is related to NPS use, of which there are several unexplored or undiscovered aspects. In particular, the issue of NPS prevalence is still controversial. On one side, the information produced from drug seizures, law enforcement activities and intoxication cases is suggestive of an extensive NPS diffusion. However, only a few studies based on hair analysis have confirmed that NPS are actually used by a large portion of people who use drugs. Likely, the main issue for testing laboratories is still the high number of existing substances and the continuous introduction of new molecules into the black market. From this perspective, sophisticated mass spectrometry-based hair testing allows labs to gain objective biological drug-prevalence information and patterns of NPS consumption in selected countries or populations. New insights into drug use can be achieved from hair analysis, possibly triangulating the results with other sources of information, such as wastewater analysis or epidemiology studies based on surveys. When the screened population and the target analytes are extended, the resulting picture becomes more definite and understandable. This approach can be applied in several scenarios to point out the unaware use of NPS, or to investigate the adulteration of low-THC cannabis with synthetic cannabinoids. Further examples of hair analysis applicability will be shown, in particular, the detection of alcohol use biomarkers, the investigation of doping cases and the interpretation of DFSA crimes.
Speakers:
Casey Burrows, Senior Application Scientist, SCIEX
Pierre Negri, Global Market Development & Marketing Manager, Forensics, SCIEX
We will discuss techniques for leveraging improved sensitivity and selectivity to conquer several challenging forensic workflows. You will learn how to routinely detect ultra-low levels of analytes extracted from challenging biological matrices. Additionally, we will explore how novel and richer fragmentation can lead to improved structural information, allowing for improved characterization and identification of novel psychoactive substances (NPS).
Wednesday November 2, 2022 | 12:00 p.m. – 2:00 p.m.
P-3 | Expanding NPS screening capabilities in the forensic toxicology laboratory
P-8 | Leveraging sensitivity improvements for low-level detection of drugs, metabolites, and endogenous hormones in complex biological matrices
P-10 | Rapid and reliable quantification of six antipsychotic drugs in serum
P-19 | Highly sensitive MS/MS detection for confident identification of potent novel synthetic opioids and their metabolites
P-26 | Enhancing high-resolution mass spectrometry performance for NPS analysis with improved sensitivity and characterization
P-31 | Quantitative analysis of designer benzodiazepines in human urine by LC-MS/MS
P-33 | Determination of novel psychoactive substances (NPS) and synthetic opioids in meconium
Co-presented by: