Build an LC-MS/MS method with me
A 3-part educational webinar series
Approach developing methods with confidence
Boost your method development capabilities
Creating a reliable and successful method can be challenging at times, especially if you’re dealing with complex matrices. Finding the right balance can take time. Samples need to be properly prepared and figuring out the right parameters for speed and sensitivity involves trial-and-error, which can be time-consuming.
We want to help make method development a whole lot easier for you. In our Build an LC-MS/MS method with me webinar series, we will guide you through the steps to create a successful method. These 45-minute sessions are led by an application chemist who will focus on building a method that can be used for detecting illicit drugs in seafood using real data collected in our lab.
Source secrets and compound tricks
Featuring Diana Tran, Applications Manager, SCIEX
February 25, 2025 | 8:00 a.m. PT / 11:00 a.m. ET / 5:00 p.m. CET
In this session you will:
- Begin the method development journey with the conceptualization of an idea and where to find resources to initiate method building
- See a thorough walkthrough of compound optimization with real life examples
- Achieve the highest level of sensitivity possible via source optimization
- Get tips for troubleshooting unfamiliar compounds and recommendations on resolutions
The path to perfect peaks: Sample preparation and chromatography for complex matrices
Featuring Kendra Adams, PhD, Applications Scientist, SCIEX
March 11, 2025 | 8:00 a.m. PT / 11:00 a.m. ET / 5:00 p.m. CET
In this session you will:
- Master LC gradient building and how to obtain optimal peak symmetry using scan methods paired with LC methods
- Explore sample preparation of drugs of abuse in food matrices and understand suppression versus extraction recovery analytes
- Learn how to handle different matrices and matrix effects
- Refine an LC-MS/MS method in real samples for sensitivity, accuracy and precision
Constructing confidence in your mass spectrometry method
Featuring Simon Roberts, PhD, Staff Applications Scientist, SCIEX
March 25, 2025 | 8:00 a.m. PT / 11:00 a.m. ET / 5:00 p.m. CET
In this session you will:
- Understand commonly used terms for validation or verification and how to establish lower limits of quantitation of the method versus the instrument
- Differentiate precision versus accuracy and how to test for either
- Get final tips on method validation