The exact cause of Parkinson disease remains unknown, but research has shown that mutations in the gene encoding LRRK2 is one of the most common causes of the disease. Jack Steed, Senior Technical Specialist at SCIEX, looks at this technical note which demonstrates a very robust and sensitive method for the quantitation of the protein LRRK2 in human CSF using the SCIEX 7500 triple quadrupole mass spectrometry coupled to the M5 MicroLC system.
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Jack joined SCIEX in 2019 as a technical specialist, his main responsibilities include the creation and proliferation of technical marketing content such as application notes and presentations as well as having a strong focus on the pharma market and small molecule analysis. Prior to joining SCIEX, Jack was employed by a CRO working mainly in small molecule method development and validation, with an emphasis on LC and LC-MS analysis.