Join us at MSACL 2019

Palm Springs Renaissance Hotel and Convention Center, Palm Springs, CA
March 31 - April 4, 2019


Visit SCIEX at booth 22/23 during MSACL 2019 in Palm Springs. Come learn about our fastest and most sensitive mass spectrometers. Join the conversation with mass spec experts at our booth and corporate workshop.

SCIEX Workshop at MSACL

Date Location Title
Wednesday, April 3, 8:00 – 8:45 AM Room 2 - Catalina Use of MS Workflows to Support HIV Clinical Trials: A Focus on Prevention

Abstract

Use of MS Workflows to Support HIV Clinical Trials: A Focus on Prevention

Antiretroviral drugs have long been used for treatment and management of HIV. Currently, a fixed dose, once-daily, oral formulation of two nucleoside reverse transcriptase inhibitors (tenofovir (TFV) disoproxil fumarate and emtricitabine) is US FDA-approved to prevent HIV acquisition in high-risk populations. The pharmacology of these compounds has been evaluated using liquid-chromatographic-mass spectrometric (LC-MS) approaches. This presentation will focus on workflows associated with the validation and implementation of bioanalytical assays to understand TFV pharmacology in assessing drug adherence, as well as in the interrogation of antiretroviral drugs as alternative drug delivery systems for HIV prevention.

Presenter

Mark Marzinke, PhD, DABCC

Director, Pre-analytical Chemistry and General Chemistry, The Johns Hopkins Hospital Dr. Mark Marzinke is an assistant professor of pathology and medicine at the Johns Hopkins University School of Medicine.

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