Liquid chromatography has traditionally been paired with mass spectrometry (LC-MS) to enable the separation of molecules on the basis of their biophysical properties, prior to entry into the mass spectrometer. While this approach is useful, there are many types of molecules and molecular features that simply do not separate well with liquid chromatography.

The charge-based separation of capillary electrophoresis with electrospray ionization mass spectrometry (CESI-MS) helps address this need by serving as an orthogonal and highly complementary partner to LC-MS. Learn how this technology is being used in a variety of application areas, such as proteomics and metabolomics studies, food analysis and pesticide testing. Discover how the high sensitivity, ultra-high resolving power, low injection volume requirements and alternative separation principles all make CESI-MS a tool that is transforming the way modern laboratories conduct their research.

Download the compendium to:

  • Achieve higher throughput, lower detection levels and the analysis of samples that contain a wide dynamic range of analyte concentrations
  • Enable increased coverage from as little as 5 μL of starting material for precious or toxic samples
  • Explore the dual functionality and flexibility of CESI-MS that provides a virtually unlimited range of separation strategies for assay optimization
  • Hear from thought leaders Dr. Neil Kelleher (Northwestern University) and Dr. Rawi Ramautar (Leiden Academic Center for Drug Research) on how they have utilized CESI-MS to enhance their research