In June 2022, the US EPA announced new drinking water health advisory levels (HALs) for 4 per- and polyfluoroalkyl substances (PFAS). In particular, these new HALs required a detection limit of 4 parts per quadrillion (ppq) for perfluorooctanoic acid (PFOA).

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  • How SCIEX and Eurofins became the first to market to achieve 4 ppq detection levels
  • The advantages of a positive-pressure, HEPA-filtered clean room
  • Why a modified SPE method requiring only a 25x concentration step eliminated the need for sample blow down and reconstitution
  • How the SCIEX 7500 system was able to detect single-digit pg/L levels
  • Ways to minimize contamination for challenging methods